BE845942A - Aminoglycosides et leur preparation - Google Patents

Aminoglycosides et leur preparation

Info

Publication number
BE845942A
BE845942A BE170428A BE170428A BE845942A BE 845942 A BE845942 A BE 845942A BE 170428 A BE170428 A BE 170428A BE 170428 A BE170428 A BE 170428A BE 845942 A BE845942 A BE 845942A
Authority
BE
Belgium
Prior art keywords
aminoglycosides
preparation
Prior art date
Application number
BE170428A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE845942A publication Critical patent/BE845942A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE170428A 1975-09-08 1976-09-08 Aminoglycosides et leur preparation BE845942A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/611,349 US3996205A (en) 1975-09-08 1975-09-08 Aminoglycoside antibiotics and intermediates

Publications (1)

Publication Number Publication Date
BE845942A true BE845942A (fr) 1977-03-08

Family

ID=24448676

Family Applications (1)

Application Number Title Priority Date Filing Date
BE170428A BE845942A (fr) 1975-09-08 1976-09-08 Aminoglycosides et leur preparation

Country Status (14)

Country Link
US (1) US3996205A (nl)
JP (1) JPS5233649A (nl)
AU (1) AU506262B2 (nl)
BE (1) BE845942A (nl)
CA (1) CA1067899A (nl)
CH (1) CH626896A5 (nl)
DE (1) DE2638794A1 (nl)
FR (2) FR2322608A1 (nl)
GB (1) GB1530643A (nl)
HU (1) HU177271B (nl)
NL (1) NL7609874A (nl)
PL (1) PL111474B1 (nl)
SU (1) SU700066A3 (nl)
ZA (1) ZA764726B (nl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182855A (en) * 1977-05-05 1980-01-08 The Upjohn Company Nitrosugar
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
EP2007783B1 (en) * 2006-04-03 2018-07-11 Technion Research & Development Foundation Ltd. Novel aminoglycosides and uses thereof in the treatment of genetic disorders
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
US10786520B2 (en) 2015-09-02 2020-09-29 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
IL295474A (en) 2015-09-02 2022-10-01 Eloxx Pharmaceuticals Ltd Aminoglycosides for the treatment of genetic diseases
US11306115B2 (en) 2015-09-02 2022-04-19 Eloxx Pharmaceuticals Ltd. Aminoglycoside derivatives and uses thereof in treating genetic disorders
CN110637024B (zh) 2017-03-15 2023-10-24 Eloxx制药有限公司 假三糖氨基糖苷及其中间体的大规模制备
WO2020105054A1 (en) 2018-11-22 2020-05-28 Technion Research & Development Foundation Limited Modified aminoglycoside compounds and uses thereof in disabling bacterial ribosome

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH84A (fr) * 1889-01-10 Fontainemelon Horlogerie Perfectionnement apporté dans la construction des mécanismes de remontoir des montres de tous calibres
JPS507595B1 (nl) * 1970-07-29 1975-03-27
US3792037A (en) * 1971-11-04 1974-02-12 Bristol Myers Co Process for preparing ambutyrosin
CA992535A (en) * 1972-03-08 1976-07-06 Bristol-Myers Squibb Company Antibiotic derivatives
US3897412A (en) * 1972-05-04 1975-07-29 Bristol Myers Co Paromomycin antibiotic derivatives
US3860574A (en) * 1972-12-06 1975-01-14 Bristol Myers Co Derivatives of neomycin b and neomycin c
US3886139A (en) * 1973-02-23 1975-05-27 Bristol Myers Co Derivatives of kanamycin
US3893997A (en) * 1974-07-01 1975-07-08 Smithkline Corp Pseudodisaccharide intermediates

Also Published As

Publication number Publication date
ZA764726B (en) 1977-07-27
FR2322608A1 (fr) 1977-04-01
US3996205A (en) 1976-12-07
CA1067899A (en) 1979-12-11
FR2355852A1 (fr) 1978-01-20
PL192253A1 (pl) 1979-02-26
NL7609874A (nl) 1977-03-10
FR2322608B1 (nl) 1979-09-07
FR2355852B1 (nl) 1980-04-04
PL111474B1 (en) 1980-08-30
DE2638794A1 (de) 1977-03-10
HU177271B (en) 1981-08-28
CH626896A5 (nl) 1981-12-15
GB1530643A (en) 1978-11-01
AU506262B2 (en) 1979-12-20
SU700066A3 (ru) 1979-11-25
JPS5233649A (en) 1977-03-14
AU1662676A (en) 1978-02-09

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: THE UPJOHN CY

Effective date: 19840908