NL7603692A - 21-Ester deriv of hydrocortisone, cortison, prednisone prednisolone - from steroid and ((1-benzyl-1H-indazol-3-yl)-oxy)acetyl chloride has anti-inflammatory props - Google Patents

21-Ester deriv of hydrocortisone, cortison, prednisone prednisolone - from steroid and ((1-benzyl-1H-indazol-3-yl)-oxy)acetyl chloride has anti-inflammatory props

Info

Publication number
NL7603692A
NL7603692A NL7603692A NL7603692A NL7603692A NL 7603692 A NL7603692 A NL 7603692A NL 7603692 A NL7603692 A NL 7603692A NL 7603692 A NL7603692 A NL 7603692A NL 7603692 A NL7603692 A NL 7603692A
Authority
NL
Netherlands
Prior art keywords
indazol
benzyl
oxy
inflammatory
cortison
Prior art date
Application number
NL7603692A
Other languages
Dutch (nl)
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Priority to NL7603692A priority Critical patent/NL7603692A/en
Publication of NL7603692A publication Critical patent/NL7603692A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

The ester (I) of (1-benzyl-1H-indazol-3-yl)-oxy acetic acid and the primary 21-OH gp. of hydrocortinsone, cortisone, prednisone and prednisolone is new. (where R1 i a single or double bond, and R2 = OH or O). Cpds. (I) exhibit a wide spectrum of anti-inflammatory activity. They can be used topically in the field of dermatology and systemically for rheumatic andallergic conditions.
NL7603692A 1976-04-08 1976-04-08 21-Ester deriv of hydrocortisone, cortison, prednisone prednisolone - from steroid and ((1-benzyl-1H-indazol-3-yl)-oxy)acetyl chloride has anti-inflammatory props NL7603692A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL7603692A NL7603692A (en) 1976-04-08 1976-04-08 21-Ester deriv of hydrocortisone, cortison, prednisone prednisolone - from steroid and ((1-benzyl-1H-indazol-3-yl)-oxy)acetyl chloride has anti-inflammatory props

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7603692A NL7603692A (en) 1976-04-08 1976-04-08 21-Ester deriv of hydrocortisone, cortison, prednisone prednisolone - from steroid and ((1-benzyl-1H-indazol-3-yl)-oxy)acetyl chloride has anti-inflammatory props

Publications (1)

Publication Number Publication Date
NL7603692A true NL7603692A (en) 1977-10-11

Family

ID=19825977

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7603692A NL7603692A (en) 1976-04-08 1976-04-08 21-Ester deriv of hydrocortisone, cortison, prednisone prednisolone - from steroid and ((1-benzyl-1H-indazol-3-yl)-oxy)acetyl chloride has anti-inflammatory props

Country Status (1)

Country Link
NL (1) NL7603692A (en)

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Legal Events

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