NL7505267A - Thieno-and thio-pyrano-benzopyran CNS active derivs - used as anti-anxiety agents and tranquillizers - Google Patents

Thieno-and thio-pyrano-benzopyran CNS active derivs - used as anti-anxiety agents and tranquillizers

Info

Publication number
NL7505267A
NL7505267A NL7505267A NL7505267A NL7505267A NL 7505267 A NL7505267 A NL 7505267A NL 7505267 A NL7505267 A NL 7505267A NL 7505267 A NL7505267 A NL 7505267A NL 7505267 A NL7505267 A NL 7505267A
Authority
NL
Netherlands
Prior art keywords
alkyl
benzopyran
thieno
tranquillizers
derivs
Prior art date
Application number
NL7505267A
Other languages
Dutch (nl)
Original Assignee
Little Inc A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Little Inc A filed Critical Little Inc A
Priority to NL7505267A priority Critical patent/NL7505267A/en
Publication of NL7505267A publication Critical patent/NL7505267A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Benzopyrans of formula (I) are new cpds. (m and n = 0-3, m + n = 2-3, R1 i 1-6C alkyl, R2 = alkyl or 3-8C cycloalkyl-1-6C alkyl, R3 = H, 1-6C alkyl, 1-6C alkanoyl, carbamyl, N-16C alkyl-carbamyl, N,N-di(1-6C alkyl)carbamyl, phosphonyl, hemisuccinate, phosphate, -(CH2)xNR4R5 or -CO(CH2)xNR4R5, x = 1-6, R4 and R5 = 1-6C alkyl). Specif. claimed are 1,2-dihydro-4,4-di-methyl-9-hydroxy-7-(3-methyl-2-octyl)- H-thieno 2,3c 1 benzopyran or 1,3-dihydro-4,4-dimethyl-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno- 3,4-c 1 benzopyran. Cpds. (I) are useful as anti-anxiety agents at doses of 0.01-20 mg/kg/day. (I) have anti-depressant and tranquillizing activity.
NL7505267A 1975-05-06 1975-05-06 Thieno-and thio-pyrano-benzopyran CNS active derivs - used as anti-anxiety agents and tranquillizers NL7505267A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL7505267A NL7505267A (en) 1975-05-06 1975-05-06 Thieno-and thio-pyrano-benzopyran CNS active derivs - used as anti-anxiety agents and tranquillizers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7505267A NL7505267A (en) 1975-05-06 1975-05-06 Thieno-and thio-pyrano-benzopyran CNS active derivs - used as anti-anxiety agents and tranquillizers

Publications (1)

Publication Number Publication Date
NL7505267A true NL7505267A (en) 1976-11-09

Family

ID=19823695

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7505267A NL7505267A (en) 1975-05-06 1975-05-06 Thieno-and thio-pyrano-benzopyran CNS active derivs - used as anti-anxiety agents and tranquillizers

Country Status (1)

Country Link
NL (1) NL7505267A (en)

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