NL7307100A - 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride - Google Patents
1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchlorideInfo
- Publication number
- NL7307100A NL7307100A NL7307100A NL7307100A NL7307100A NL 7307100 A NL7307100 A NL 7307100A NL 7307100 A NL7307100 A NL 7307100A NL 7307100 A NL7307100 A NL 7307100A NL 7307100 A NL7307100 A NL 7307100A
- Authority
- NL
- Netherlands
- Prior art keywords
- dimethoxy
- acetic acid
- benzyloxybenzoyl
- dimethylpyrogallol
- sulphurylchloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
Abstract
Cpds. of formula (I) are new: (where R = -CH(Cl)COOR" when R' = benzyl; or -CH2Cl when R' = H; R" = alkyl). (I) are intermediates in the preparation of pharmaceutically-active compounds. A soln. of 72 ml. sulphuryl chloride in 250 ml. acetic acid is added over 1 hour to a soln. of 272 g. methyl alpha-(3,5-dimethoxy-4-benzyloxybenzoyl)acetate in 510 ml. acetic acid. After stirring for 1/4 hour, 340 ml. conc. HCl are added and refluxed for 1 hour. Working up gives 164 g. of omega-chloro-3,5-dimethoxy-4-hydroxyacetophenone, m.pt. 148-150 degrees C.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7307100A NL7307100A (en) | 1973-05-22 | 1973-05-22 | 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride |
JP4705574A JPS5014653A (en) | 1973-05-22 | 1974-04-24 | |
FI128674A FI128674A (en) | 1973-05-22 | 1974-04-25 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7307100A NL7307100A (en) | 1973-05-22 | 1973-05-22 | 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7307100A true NL7307100A (en) | 1974-11-26 |
Family
ID=19818913
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7307100A NL7307100A (en) | 1973-05-22 | 1973-05-22 | 1,3-dimethylpyrogallol derivs pharmaceutical inters - prepd. from (3,5-dimethoxy-benzyloxybenzoyl)acetic acid methyl ester and sulphurylchloride |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS5014653A (en) |
FI (1) | FI128674A (en) |
NL (1) | NL7307100A (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59189200A (en) * | 1983-04-11 | 1984-10-26 | 株式会社日本触媒 | Method of cleaning substance surface |
CN100344616C (en) | 2001-06-12 | 2007-10-24 | 维尔斯达医疗公司 | Compounds for the treatment of metabolic disorders |
-
1973
- 1973-05-22 NL NL7307100A patent/NL7307100A/en not_active Application Discontinuation
-
1974
- 1974-04-24 JP JP4705574A patent/JPS5014653A/ja active Pending
- 1974-04-25 FI FI128674A patent/FI128674A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
JPS5014653A (en) | 1975-02-15 |
FI128674A (en) | 1974-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BV | The patent application has lapsed |