NL7300838A - - Google Patents

Info

Publication number
NL7300838A
NL7300838A NL7300838A NL7300838A NL7300838A NL 7300838 A NL7300838 A NL 7300838A NL 7300838 A NL7300838 A NL 7300838A NL 7300838 A NL7300838 A NL 7300838A NL 7300838 A NL7300838 A NL 7300838A
Authority
NL
Netherlands
Application number
NL7300838A
Other versions
NL180749B (nl
NL180749C (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7300838A publication Critical patent/NL7300838A/xx
Publication of NL180749B publication Critical patent/NL180749B/xx
Application granted granted Critical
Publication of NL180749C publication Critical patent/NL180749C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7300838A 1972-01-20 1973-01-19 Werkwijze ter bereiding van een farmaceutisch preparaat met antihistaminewerking en werking op het cardiovasculaire systeem, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte piperidinederivaten. NL180749C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB272072A GB1404003A (en) 1972-01-20 1972-01-20 N-substituted-4-amidopiperidines tetrahydropyridines and pyridines

Publications (3)

Publication Number Publication Date
NL7300838A true NL7300838A (cs) 1973-07-24
NL180749B NL180749B (nl) 1986-11-17
NL180749C NL180749C (nl) 1987-04-16

Family

ID=9744619

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7300838A NL180749C (nl) 1972-01-20 1973-01-19 Werkwijze ter bereiding van een farmaceutisch preparaat met antihistaminewerking en werking op het cardiovasculaire systeem, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte piperidinederivaten.

Country Status (8)

Country Link
JP (1) JPS59507B2 (cs)
BE (1) BE794333A (cs)
CA (1) CA984843A (cs)
CH (2) CH590840A5 (cs)
DE (1) DE2302717A1 (cs)
FR (1) FR2181678B1 (cs)
GB (1) GB1404003A (cs)
NL (1) NL180749C (cs)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1542137A (en) * 1976-03-12 1979-03-14 Wyeth John & Brother Ltd Process for preparing 3(piperidinoalkyl)indoles
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
GB1582239A (en) 1976-12-11 1981-01-07 Wyeth John & Brother Ltd Piperidin-4-yl ureas and thioureas
JPS54160371A (en) * 1978-06-02 1979-12-19 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agents comprising it
US4246268A (en) * 1979-02-09 1981-01-20 Richardson-Merrell Inc. Neuroleptic-4-(naphthylmethyl)piperidine derivatives
US4329348A (en) 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4242347A (en) 1979-06-18 1980-12-30 Ciba-Geigy Corporation Hypotensive indolylalkylpiperidyl guanidines and isoureas
EP0025111B1 (en) * 1979-08-10 1984-07-25 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
US4432984A (en) * 1980-03-27 1984-02-21 Emile Bouchara Anti-hypertensive benzodioxan derivatives
US4410528A (en) * 1980-05-16 1983-10-18 Kyowa Hakko Kogyo Co., Ltd. Hypotensive piperidine derivatives
DE3025385A1 (de) * 1980-07-04 1982-01-28 Boehringer Mannheim Gmbh, 6800 Mannheim Neue tricyclische arylether, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
US4359468A (en) * 1981-02-25 1982-11-16 Boehringer Ingelheim Ltd. Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones
DE60125335T2 (de) 2000-03-06 2007-07-12 Acadia Pharmaceuticals Inc., San Diego Azacyclische verbindungen zur verwendung in der behandlung von mit serotonin verwandten krankheiten
JP4535728B2 (ja) 2001-12-28 2010-09-01 アカディア ファーマシューティカルズ,インコーポレーテッド モノアミン受容体調節因子としてのスピロアザ環式化合物
US7253186B2 (en) 2002-06-24 2007-08-07 Carl-Magnus Andersson N-substituted piperidine derivatives as serotonin receptor agents
NZ537522A (en) 2002-06-24 2006-07-28 Acadia Pharm Inc N-substituted piperidine derivatives as serotonin receptor agents
US7538222B2 (en) 2002-06-24 2009-05-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
CN1816524B (zh) 2003-01-16 2012-06-27 阿卡蒂亚药品公司 用于神经退行性疾病的治疗的选择性五羟色胺2a/2c受体反向激动剂
US7820695B2 (en) 2004-05-21 2010-10-26 Acadia Pharmaceuticals, Inc. Selective serotonin receptor inverse agonists as therapeutics for disease
US20050261278A1 (en) 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US7790899B2 (en) 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
CA2580129A1 (en) 2004-09-27 2006-04-06 Acadia Pharmaceuticals Inc. Salts of n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and their preparation
AU2008228833B9 (en) 2007-03-19 2013-10-24 Acadia Pharmaceuticals Inc. Combinations of 5-HT2A inverse agonists and antagonists with antipsychotics
SI3325444T1 (sl) 2015-07-20 2021-11-30 Acadia Pharmaceuticals Inc. Postopki za pripravo N-(4-fluorobenzil)-N-(1-metilpiperidin-4-il)-N'- (4-(2-metilpropiloksi)fenilmetil)karbamida in njegove tartratne soli in polimorfne oblike C
WO2017165635A1 (en) 2016-03-25 2017-09-28 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome p450 modulators
US10953000B2 (en) 2016-03-25 2021-03-23 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome P450 modulators
US11464768B2 (en) 2016-12-20 2022-10-11 Acadia Pharmaceuticals Inc. Pimavanserin alone or in combination for use in the treatment of Alzheimer's disease psychosis
US11135211B2 (en) 2017-04-28 2021-10-05 Acadia Pharmaceuticals Inc. Pimavanserin for treating impulse control disorder
WO2019046167A1 (en) 2017-08-30 2019-03-07 Acadia Pharmaceuticals Inc. PIMAVANSERIN FORMULATIONS

Also Published As

Publication number Publication date
CA984843A (en) 1976-03-02
CH595347A5 (cs) 1978-02-15
BE794333A (fr) 1973-07-19
GB1404003A (en) 1975-08-28
CH590840A5 (cs) 1977-08-31
JPS59507B2 (ja) 1984-01-07
NL180749B (nl) 1986-11-17
FR2181678B1 (cs) 1976-09-03
JPS4880569A (cs) 1973-10-29
DE2302717A1 (de) 1973-07-26
FR2181678A1 (cs) 1973-12-07
NL180749C (nl) 1987-04-16

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Legal Events

Date Code Title Description
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee