CH595347A5 - - Google Patents
Info
- Publication number
- CH595347A5 CH595347A5 CH1392476A CH1392476A CH595347A5 CH 595347 A5 CH595347 A5 CH 595347A5 CH 1392476 A CH1392476 A CH 1392476A CH 1392476 A CH1392476 A CH 1392476A CH 595347 A5 CH595347 A5 CH 595347A5
- Authority
- CH
- Switzerland
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB272072A GB1404003A (en) | 1972-01-20 | 1972-01-20 | N-substituted-4-amidopiperidines tetrahydropyridines and pyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH595347A5 true CH595347A5 (cs) | 1978-02-15 |
Family
ID=9744619
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH82873A CH590840A5 (cs) | 1972-01-20 | 1973-01-19 | |
| CH1392476A CH595347A5 (cs) | 1972-01-20 | 1973-01-19 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH82873A CH590840A5 (cs) | 1972-01-20 | 1973-01-19 |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS59507B2 (cs) |
| BE (1) | BE794333A (cs) |
| CA (1) | CA984843A (cs) |
| CH (2) | CH590840A5 (cs) |
| DE (1) | DE2302717A1 (cs) |
| FR (1) | FR2181678B1 (cs) |
| GB (1) | GB1404003A (cs) |
| NL (1) | NL180749C (cs) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1542137A (en) * | 1976-03-12 | 1979-03-14 | Wyeth John & Brother Ltd | Process for preparing 3(piperidinoalkyl)indoles |
| US4146630A (en) * | 1976-11-12 | 1979-03-27 | Boehringer Mannheim Gmbh | Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers |
| GB1582239A (en) | 1976-12-11 | 1981-01-07 | Wyeth John & Brother Ltd | Piperidin-4-yl ureas and thioureas |
| JPS54160371A (en) * | 1978-06-02 | 1979-12-19 | Kyowa Hakko Kogyo Co Ltd | Novel piperidine derivative and hypotensive agents comprising it |
| US4246268A (en) * | 1979-02-09 | 1981-01-20 | Richardson-Merrell Inc. | Neuroleptic-4-(naphthylmethyl)piperidine derivatives |
| US4329348A (en) | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| US4242347A (en) | 1979-06-18 | 1980-12-30 | Ciba-Geigy Corporation | Hypotensive indolylalkylpiperidyl guanidines and isoureas |
| EP0025111B1 (en) * | 1979-08-10 | 1984-07-25 | Sandoz Ag | 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them |
| US4432984A (en) * | 1980-03-27 | 1984-02-21 | Emile Bouchara | Anti-hypertensive benzodioxan derivatives |
| US4410528A (en) * | 1980-05-16 | 1983-10-18 | Kyowa Hakko Kogyo Co., Ltd. | Hypotensive piperidine derivatives |
| DE3025385A1 (de) * | 1980-07-04 | 1982-01-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue tricyclische arylether, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| DE3200304A1 (de) * | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
| US4359468A (en) * | 1981-02-25 | 1982-11-16 | Boehringer Ingelheim Ltd. | Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones |
| DE60125335T2 (de) | 2000-03-06 | 2007-07-12 | Acadia Pharmaceuticals Inc., San Diego | Azacyclische verbindungen zur verwendung in der behandlung von mit serotonin verwandten krankheiten |
| JP4535728B2 (ja) | 2001-12-28 | 2010-09-01 | アカディア ファーマシューティカルズ，インコーポレーテッド | モノアミン受容体調節因子としてのスピロアザ環式化合物 |
| US7253186B2 (en) | 2002-06-24 | 2007-08-07 | Carl-Magnus Andersson | N-substituted piperidine derivatives as serotonin receptor agents |
| NZ537522A (en) | 2002-06-24 | 2006-07-28 | Acadia Pharm Inc | N-substituted piperidine derivatives as serotonin receptor agents |
| US7538222B2 (en) | 2002-06-24 | 2009-05-26 | Acadia Pharmaceuticals, Inc. | N-substituted piperidine derivatives as serotonin receptor agents |
| CN1816524B (zh) | 2003-01-16 | 2012-06-27 | 阿卡蒂亚药品公司 | 用于神经退行性疾病的治疗的选择性五羟色胺2a/2c受体反向激动剂 |
| US7820695B2 (en) | 2004-05-21 | 2010-10-26 | Acadia Pharmaceuticals, Inc. | Selective serotonin receptor inverse agonists as therapeutics for disease |
| US20050261278A1 (en) | 2004-05-21 | 2005-11-24 | Weiner David M | Selective serotonin receptor inverse agonists as therapeutics for disease |
| US7790899B2 (en) | 2004-09-27 | 2010-09-07 | Acadia Pharmaceuticals, Inc. | Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms |
| CA2580129A1 (en) | 2004-09-27 | 2006-04-06 | Acadia Pharmaceuticals Inc. | Salts of n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and their preparation |
| AU2008228833B9 (en) | 2007-03-19 | 2013-10-24 | Acadia Pharmaceuticals Inc. | Combinations of 5-HT2A inverse agonists and antagonists with antipsychotics |
| SI3325444T1 (sl) | 2015-07-20 | 2021-11-30 | Acadia Pharmaceuticals Inc. | Postopki za pripravo N-(4-fluorobenzil)-N-(1-metilpiperidin-4-il)-N'- (4-(2-metilpropiloksi)fenilmetil)karbamida in njegove tartratne soli in polimorfne oblike C |
| WO2017165635A1 (en) | 2016-03-25 | 2017-09-28 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome p450 modulators |
| US10953000B2 (en) | 2016-03-25 | 2021-03-23 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome P450 modulators |
| US11464768B2 (en) | 2016-12-20 | 2022-10-11 | Acadia Pharmaceuticals Inc. | Pimavanserin alone or in combination for use in the treatment of Alzheimer's disease psychosis |
| US11135211B2 (en) | 2017-04-28 | 2021-10-05 | Acadia Pharmaceuticals Inc. | Pimavanserin for treating impulse control disorder |
| WO2019046167A1 (en) | 2017-08-30 | 2019-03-07 | Acadia Pharmaceuticals Inc. | PIMAVANSERIN FORMULATIONS |
-
0
- BE BE794333D patent/BE794333A/xx not_active IP Right Cessation
-
1972
- 1972-01-20 GB GB272072A patent/GB1404003A/en not_active Expired
-
1973
- 1973-01-09 CA CA160,793A patent/CA984843A/en not_active Expired
- 1973-01-19 FR FR7302013A patent/FR2181678B1/fr not_active Expired
- 1973-01-19 DE DE19732302717 patent/DE2302717A1/de not_active Ceased
- 1973-01-19 JP JP845573A patent/JPS59507B2/ja not_active Expired
- 1973-01-19 NL NL7300838A patent/NL180749C/xx not_active IP Right Cessation
- 1973-01-19 CH CH82873A patent/CH590840A5/xx not_active IP Right Cessation
- 1973-01-19 CH CH1392476A patent/CH595347A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA984843A (en) | 1976-03-02 |
| BE794333A (fr) | 1973-07-19 |
| GB1404003A (en) | 1975-08-28 |
| CH590840A5 (cs) | 1977-08-31 |
| JPS59507B2 (ja) | 1984-01-07 |
| NL180749B (nl) | 1986-11-17 |
| FR2181678B1 (cs) | 1976-09-03 |
| JPS4880569A (cs) | 1973-10-29 |
| DE2302717A1 (de) | 1973-07-26 |
| FR2181678A1 (cs) | 1973-12-07 |
| NL7300838A (cs) | 1973-07-24 |
| NL180749C (nl) | 1987-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |