NL7209299A - Delta-4-3-oxo-11-beta-halo steroids - with hormonal activity - Google Patents
Delta-4-3-oxo-11-beta-halo steroids - with hormonal activityInfo
- Publication number
- NL7209299A NL7209299A NL7209299A NL7209299A NL7209299A NL 7209299 A NL7209299 A NL 7209299A NL 7209299 A NL7209299 A NL 7209299A NL 7209299 A NL7209299 A NL 7209299A NL 7209299 A NL7209299 A NL 7209299A
- Authority
- NL
- Netherlands
- Prior art keywords
- oxo
- delta
- beta
- alkyl
- hormonal activity
- Prior art date
Links
Abstract
Cpds are of formula (I) (where R1 is 1-3C alkyl; R2 is O or (alpha-Q); P is H or 1-4C alkyl, alkenyl or alkynyl; Q is free, esterified or etherified OH; R3 is H or Me; R4 is F, Cl or Br) and are prepd. by reacting the corresp. 11 alpha-hydroxy cpd., in which the keto gps. are opt. protected, with a halogenating agent, pref. of formula (II). R5R6N-CR7R8-CR9R10R11 (where R5 and R6 are alkyl, aryl or aralkyl, or NR5R6 is a heterocycle; R7 and R10 are halogen; R8 is F, Cl or Br and R9 is H, or R8 + R9 form a C-C bond; R11 is F, Cl, Br or CF3). Cpds. (I) have a wide range of hormonal activities.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7209299A NL7209299A (en) | 1972-07-01 | 1972-07-01 | Delta-4-3-oxo-11-beta-halo steroids - with hormonal activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7209299A NL7209299A (en) | 1972-07-01 | 1972-07-01 | Delta-4-3-oxo-11-beta-halo steroids - with hormonal activity |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7209299A true NL7209299A (en) | 1974-01-03 |
Family
ID=19816456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7209299A NL7209299A (en) | 1972-07-01 | 1972-07-01 | Delta-4-3-oxo-11-beta-halo steroids - with hormonal activity |
Country Status (1)
Country | Link |
---|---|
NL (1) | NL7209299A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0092173A1 (en) * | 1982-04-16 | 1983-10-26 | Schering Aktiengesellschaft | 11-Beta-chlorosteroids, process for their preparation and pharmaceutical compositions containing them |
EP0092174A1 (en) * | 1982-04-16 | 1983-10-26 | Schering Aktiengesellschaft | 11-Beta-chloro-delta-15-steroids, process for their preparation and pharmaceutical compositions containing them |
-
1972
- 1972-07-01 NL NL7209299A patent/NL7209299A/en unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0092173A1 (en) * | 1982-04-16 | 1983-10-26 | Schering Aktiengesellschaft | 11-Beta-chlorosteroids, process for their preparation and pharmaceutical compositions containing them |
EP0092174A1 (en) * | 1982-04-16 | 1983-10-26 | Schering Aktiengesellschaft | 11-Beta-chloro-delta-15-steroids, process for their preparation and pharmaceutical compositions containing them |
US4464365A (en) * | 1982-04-16 | 1984-08-07 | Schering Aktiengesellschaft | 11β-Chloro-Δ15 -steroids, a process for their preparation and pharmaceutical preparations containing them |
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