NL6716753A - - Google Patents

Info

Publication number
NL6716753A
NL6716753A NL6716753A NL6716753A NL6716753A NL 6716753 A NL6716753 A NL 6716753A NL 6716753 A NL6716753 A NL 6716753A NL 6716753 A NL6716753 A NL 6716753A NL 6716753 A NL6716753 A NL 6716753A
Authority
NL
Netherlands
Application number
NL6716753A
Other versions
NL142677B (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL6716753A publication Critical patent/NL6716753A/xx
Publication of NL142677B publication Critical patent/NL142677B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
NL676716753A 1966-12-09 1967-12-08 Werkwijze voor de bereiding van een preparaat met tranquilliserende werking, gevormd preparaat en werkwijze voor de bereiding van een verbinding met tranquilliserende werking, resp. de niet-giftige zuuradditiezouten daarvan, geschikt voor gebruik daarbij. NL142677B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO001000 1966-12-09

Publications (2)

Publication Number Publication Date
NL6716753A true NL6716753A (de) 1968-06-10
NL142677B NL142677B (nl) 1974-07-15

Family

ID=10996660

Family Applications (1)

Application Number Title Priority Date Filing Date
NL676716753A NL142677B (nl) 1966-12-09 1967-12-08 Werkwijze voor de bereiding van een preparaat met tranquilliserende werking, gevormd preparaat en werkwijze voor de bereiding van een verbinding met tranquilliserende werking, resp. de niet-giftige zuuradditiezouten daarvan, geschikt voor gebruik daarbij.

Country Status (9)

Country Link
US (1) US3736315A (de)
AT (3) AT279617B (de)
BE (1) BE707730A (de)
CH (1) CH519507A (de)
DE (1) DE1670642C3 (de)
DK (2) DK118660B (de)
FR (1) FR6852M (de)
NL (1) NL142677B (de)
SE (1) SE324154B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30014E (en) * 1966-12-09 1979-05-29 Egyesult Gyogyazer-es Tapozergyar 1-(3,4-Dimethoxy-phenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines
HU195788B (en) * 1986-05-21 1988-07-28 Gyogyszerkutato Intezet Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them
HUP9701284A3 (en) * 1997-07-24 2005-11-28 Egyt Gyogyszervegyeszeti Gyar Use of 2,3-benzodiazepine derivatives for producing pharmaceutical compositions for treating and prophylacting illnesses and conditions connected with the endogene opioide system
ATE269705T1 (de) * 1998-10-27 2004-07-15 Vela Pharmaceuticals Inc Verwendung von optisch reinem (r)-tofizopam zur behandlung und pravention von angststörungen
US6080736A (en) * 1999-10-27 2000-06-27 Janus Pharmaceuticals, Inc. Methods and compositions for treating and preventing anxiety and anxiety disorders using optically pure (R) tofisopam
FR2824065A1 (fr) * 2001-04-26 2002-10-31 Neuro3D Composes inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations
US6649607B2 (en) * 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US20040152695A1 (en) * 2002-12-03 2004-08-05 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine and uses thereof
CA2508542A1 (en) * 2002-12-03 2004-06-17 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5h-2,3-benzodiazepine and uses thereof
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
CA2525273C (en) * 2003-05-16 2012-04-17 Vela Pharmaceuticals, Inc. Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (r) 2,3-benzodiazepine
US20070021412A1 (en) * 2003-05-16 2007-01-25 Vela Pharmaceuticals, Inc. Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (S) 2,3-benzodiazepine
US20050288277A1 (en) * 2004-06-25 2005-12-29 Kucharik Robert F Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (S)-2,3-benzodiazepine
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines
FR2870539B1 (fr) * 2004-05-19 2006-08-04 Greenpharma Sa Sa Nouvelles methodes et medicaments
US7541355B2 (en) * 2005-05-23 2009-06-02 Vela Acquisition Corporation Conversion process for 2,3-benzodiazepine enantiomers
CN107915688A (zh) * 2016-10-09 2018-04-17 北京阜康仁生物制药科技有限公司 一种托非索泮的合成工艺改进方法

Also Published As

Publication number Publication date
AT279618B (de) 1970-03-10
CH519507A (de) 1972-02-29
AT279617B (de) 1970-03-10
FR6852M (de) 1969-04-08
AT278797B (de) 1970-02-10
DK118660B (da) 1970-09-21
DE1670642B2 (de) 1978-09-07
DE1670642C3 (de) 1979-05-03
NL142677B (nl) 1974-07-15
SE324154B (de) 1970-05-25
DK125650B (da) 1973-03-19
US3736315A (en) 1973-05-29
BE707730A (de) 1968-04-16
DE1670642A1 (de) 1971-03-18

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Legal Events

Date Code Title Description
NL80 Information provided on patent owner name for an already discontinued patent

Owner name: E G Y T

V4 Discontinued because of reaching the maximum lifetime of a patent