NL6712584A - - Google Patents
Info
- Publication number
- NL6712584A NL6712584A NL6712584A NL6712584A NL6712584A NL 6712584 A NL6712584 A NL 6712584A NL 6712584 A NL6712584 A NL 6712584A NL 6712584 A NL6712584 A NL 6712584A NL 6712584 A NL6712584 A NL 6712584A
- Authority
- NL
- Netherlands
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/48—Y being a hydrogen or a carbon atom
- C07C275/50—Y being a hydrogen or an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/10—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58393766A | 1966-10-03 | 1966-10-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL6712584A true NL6712584A (sv) | 1968-04-04 |
| NL149484B NL149484B (nl) | 1976-05-17 |
Family
ID=24335223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL676712584A NL149484B (nl) | 1966-10-03 | 1967-09-14 | Werkwijze voor de bereiding van 1-(4-halogeenfenyl)1-(3-trifluormethylfenoxy)azijnzuuresters met hypocholesterolemische werking, alsmede van therapeutisch actieve preparaten, die deze esters bevatten en de aldus verkregen gevormde preparaten. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3517050A (sv) |
| AT (2) | AT279590B (sv) |
| BE (1) | BE704574A (sv) |
| BR (1) | BR6793319D0 (sv) |
| CH (1) | CH512422A (sv) |
| CS (1) | CS170496B2 (sv) |
| CY (1) | CY650A (sv) |
| DE (1) | DE1643460A1 (sv) |
| DK (1) | DK120955B (sv) |
| ES (1) | ES345582A1 (sv) |
| FI (1) | FI48064C (sv) |
| FR (2) | FR1573841A (sv) |
| GB (1) | GB1182007A (sv) |
| GR (1) | GR34667B (sv) |
| MY (1) | MY7300079A (sv) |
| NL (1) | NL149484B (sv) |
| NO (1) | NO121787B (sv) |
| SE (1) | SE332182B (sv) |
| YU (1) | YU32921B (sv) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3923855A (en) * | 1972-07-13 | 1975-12-02 | Merck & Co Inc | 2-sulfonyloxyethyl 3-trifluoromethylphenoxy-4{40 -chlorophenyl acetate |
| US4110351A (en) * | 1973-04-02 | 1978-08-29 | Richardson-Merrell Inc. | Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts |
| DK115374A (sv) | 1974-03-04 | 1975-11-03 | Byk Gulden Lomberg Chem Fab | |
| IL48707A0 (en) * | 1974-12-30 | 1976-02-29 | Synthelabo | Novel phenylacetic acid derivatives,their preparation and pharmaceutical compositions containing them |
| FR2424247A2 (fr) * | 1978-04-27 | 1979-11-23 | Science Union & Cie | Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention |
| US4250191A (en) * | 1978-11-30 | 1981-02-10 | Edwards K David | Preventing renal failure |
| US7576131B2 (en) * | 1999-06-04 | 2009-08-18 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| US6624194B1 (en) * | 1999-06-04 | 2003-09-23 | Metabolex, Inc. | Use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| US6262118B1 (en) * | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
| AU2002251978B2 (en) * | 2001-02-09 | 2007-07-19 | Merck & Co., Inc. | 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders |
| CA2529774C (en) * | 2003-06-20 | 2014-05-27 | Metabolex, Inc. | Resolution of .alpha.-(phenoxy)phenylacetic acid derivatives |
| US7199259B2 (en) * | 2003-06-20 | 2007-04-03 | Metabolex, Inc. | Resolution of α-(phenoxy)phenylacetic acid derivatives |
| CN100525757C (zh) * | 2003-06-20 | 2009-08-12 | 麦它波莱克斯股份有限公司 | α-(苯氧基)苯乙酸衍生物的拆分 |
| KR20070011312A (ko) | 2004-02-18 | 2007-01-24 | 메타볼렉스, 인코포레이티드 | 항당뇨병제로서 알파-(트리플루오로메틸-치환된 아릴옥시,아릴아미노, 아릴티오 또는아릴메틸)-트리플루오로메틸-치환된 페닐아세트산 및 이의유도체 |
| JP2008500357A (ja) * | 2004-05-25 | 2008-01-10 | メタボレックス インコーポレーティッド | Ｐｐａｒのモジュレーターとしての置換されたトリアゾールおよびこれらの調製方法 |
| WO2005115384A2 (en) * | 2004-05-25 | 2005-12-08 | Metabolex, Inc. | Bicyclic, substituted triazoles as modulators of ppar and methods of their preparation |
| JP2008533206A (ja) | 2005-03-21 | 2008-08-21 | メタボレックス インコーポレーティッド | 代謝、炎症、および心血管障害の処置における浮腫を回避するための方法 |
| US7714131B2 (en) * | 2005-09-23 | 2010-05-11 | Metabolex, Inc. | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof |
| US7432394B2 (en) * | 2005-09-23 | 2008-10-07 | Metabolex, Inc. | Resolution of α-(phenoxy) phenylacetic acid derivatives with naphthyl-alkylamines |
| WO2009121940A1 (en) * | 2008-04-03 | 2009-10-08 | Janssen Pharmaceutica Nv | Process for the preparation of (-)-(4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester |
| US9023856B2 (en) | 2011-11-04 | 2015-05-05 | Cymabay Therapeutics, Inc. | Methods for treating hyperuricemia in patients with gout using halofenate or halogenic acid and a second urate-lowering agent |
| US9060987B2 (en) | 2011-11-04 | 2015-06-23 | Cymabay Therapeutics, Inc. | Methods for treating gout flares |
| WO2013167996A1 (en) * | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of metabolic syndrome |
| CN105143172B (zh) * | 2013-01-18 | 2016-12-14 | 西玛贝医药公司 | 用于降脂酰胺制备的dcc介导的偶联 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES251290A1 (es) * | 1958-08-21 | 1960-04-01 | Parke Davis & Co | Un procedimiento para la producciën de alcohilaminas arilsustituidas |
-
1966
- 1966-10-03 US US583937A patent/US3517050A/en not_active Expired - Lifetime
-
1967
- 1967-09-14 NL NL676712584A patent/NL149484B/xx unknown
- 1967-09-20 CS CS6703A patent/CS170496B2/cs unknown
- 1967-09-20 NO NO169792A patent/NO121787B/no unknown
- 1967-09-21 YU YU1851/67A patent/YU32921B/xx unknown
- 1967-09-22 GR GR670134667A patent/GR34667B/el unknown
- 1967-09-22 FI FI672535A patent/FI48064C/sv active
- 1967-09-26 DK DK477867AA patent/DK120955B/da unknown
- 1967-09-26 BR BR193319/67A patent/BR6793319D0/pt unknown
- 1967-09-27 SE SE13273/67A patent/SE332182B/xx unknown
- 1967-09-27 GB GB44020/67A patent/GB1182007A/en not_active Expired
- 1967-09-29 ES ES345582A patent/ES345582A1/es not_active Expired
- 1967-09-29 AT AT888067A patent/AT279590B/de not_active IP Right Cessation
- 1967-10-02 BE BE704574D patent/BE704574A/xx unknown
- 1967-10-02 DE DE19671643460 patent/DE1643460A1/de not_active Withdrawn
- 1967-10-02 FR FR1573841D patent/FR1573841A/fr not_active Expired
- 1967-10-02 CH CH1369767A patent/CH512422A/de not_active IP Right Cessation
- 1967-10-03 AT AT03550/69A patent/AT282617B/de not_active IP Right Cessation
- 1967-12-29 FR FR134252A patent/FR8372M/fr not_active Expired
-
1972
- 1972-07-12 CY CY65072A patent/CY650A/xx unknown
-
1973
- 1973-12-31 MY MY197379A patent/MY7300079A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE332182B (sv) | 1971-02-01 |
| AT282617B (de) | 1970-07-10 |
| US3517050A (en) | 1970-06-23 |
| CY650A (en) | 1972-07-12 |
| GR34667B (el) | 1968-06-05 |
| ES345582A1 (es) | 1970-02-01 |
| BE704574A (sv) | 1968-04-02 |
| FI48064B (sv) | 1974-02-28 |
| AT279590B (de) | 1970-03-10 |
| DE1643460A1 (de) | 1971-01-28 |
| DK120955B (da) | 1971-08-09 |
| YU32921B (en) | 1975-12-31 |
| NL149484B (nl) | 1976-05-17 |
| NO121787B (sv) | 1971-04-13 |
| BR6793319D0 (pt) | 1973-05-24 |
| CH512422A (de) | 1971-09-15 |
| YU185167A (en) | 1975-06-30 |
| FI48064C (sv) | 1974-06-10 |
| MY7300079A (en) | 1973-12-31 |
| FR8372M (sv) | 1971-02-22 |
| GB1182007A (en) | 1970-02-25 |
| FR1573841A (sv) | 1969-07-11 |
| CS170496B2 (sv) | 1976-08-27 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| VJC | Lapsed due to non-payment of the due maintenance fee for the patent or patent application | ||
| NL80 | Information provided on patent owner name for an already discontinued patent |
Owner name: MERCK |