NL279830A - - Google Patents

Info

Publication number
NL279830A
NL279830A NL279830DA NL279830A NL 279830 A NL279830 A NL 279830A NL 279830D A NL279830D A NL 279830DA NL 279830 A NL279830 A NL 279830A
Authority
NL
Netherlands
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of NL279830A publication Critical patent/NL279830A/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/46Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL279830D 1961-06-20 NL279830A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US118243A US3405122A (en) 1961-06-20 1961-06-20 Novel 3h-1, 4-benzodiazepin-2-(1h)-ones
US130757A US3100770A (en) 1961-06-20 1961-08-11 5-pyridyl-1,4-benzodiazepine compounds
US326340A US3398159A (en) 1961-06-20 1963-11-27 Aminophenyl heterocyclic ketones
US326341A US3407211A (en) 1961-06-20 1963-11-27 Acylaminophenyl heterocyclic ketones
US326338A US3400128A (en) 1961-06-20 1963-11-27 Heterocyclic intermediates

Publications (1)

Publication Number Publication Date
NL279830A true NL279830A (es)

Family

ID=27537521

Family Applications (4)

Application Number Title Priority Date Filing Date
NL131733D NL131733C (es) 1961-06-20
NL279830D NL279830A (es) 1961-06-20
NL122319D NL122319C (es) 1961-06-20
NL6700180A NL6700180A (es) 1961-06-20 1967-01-05

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL131733D NL131733C (es) 1961-06-20

Family Applications After (2)

Application Number Title Priority Date Filing Date
NL122319D NL122319C (es) 1961-06-20
NL6700180A NL6700180A (es) 1961-06-20 1967-01-05

Country Status (7)

Country Link
US (5) US3405122A (es)
CH (4) CH445501A (es)
DE (1) DE1445862A1 (es)
FR (1) FR1978M (es)
GB (1) GB948888A (es)
NL (4) NL6700180A (es)
SE (4) SE301811B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3261828A (en) * 1962-10-04 1966-07-19 Hoffmann La Roche 3h-1,4-benzodiazepine-2,5(1h,4h)-dione compounds
US3184448A (en) * 1962-10-16 1965-05-18 American Home Prod Benzodiazepinium compounds
US3336296A (en) * 1962-10-26 1967-08-15 American Home Prod Preparation of 5-substituted-2h-1, 4-benzodiazepin-2-one-4-oxides
US3192199A (en) * 1963-03-01 1965-06-29 Freeman H Mcmillan Process for the production of 1-cycloalkyl derivatives of 1, 4-benzodiazepine
US3321467A (en) * 1963-11-27 1967-05-23 Hoffmann La Roche 3-halo-1, 4-benzodiazepin-2-ones
US3182067A (en) * 1964-04-09 1965-05-04 Hoffmann La Roche Benzodiazepine compounds
NL131731C (es) * 1965-12-09
US3678043A (en) * 1966-03-14 1972-07-18 American Home Prod 2,3-dihydro-2-oxo-1h-1,4-benzodiazepine-3-carboxylic acid esters and related compounds
US3429874A (en) * 1966-12-22 1969-02-25 Schering Corp 1-polyhalogenoalkyl-2-oxo-1,3-dihydro-2h-1,4-benzodiazepines
US3506403A (en) * 1967-12-19 1970-04-14 Hoffmann La Roche Colorimetric method for determining iron in fluids
US3506404A (en) * 1967-12-19 1970-04-14 Hoffmann La Roche Colorimetric method for determining iron in blood
US3551427A (en) * 1969-05-09 1970-12-29 Sandoz Ag 4-thienyl-2-(1h)-quinazolones
US3856802A (en) * 1971-05-10 1974-12-24 Upjohn Co 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES
US4089953A (en) * 1973-06-20 1978-05-16 Ddsa Pharmaceuticals 1,5-Benzodiazocines
DE3124013A1 (de) * 1981-06-19 1982-12-30 Kali-Chemie Pharma Gmbh, 3000 Hannover 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IE903879A1 (en) * 1989-10-30 1991-05-08 Hoffmann La Roche Use of a benzodiazepine and a phenylpyrrylketone derivative
US5036101A (en) * 1989-10-30 1991-07-30 Hoffmann-La Roche Inc. Method for treating retroviral infections with aryl-(2-pyrryl) ketone compound
US5164376A (en) * 1989-10-30 1992-11-17 Hoffmann-Laroche Inc. Method for treating retroviral infections with aryl-(2-pyrryl) keytone compound
US5041438A (en) * 1989-10-30 1991-08-20 Hoffmann-La Roche Inc. Method for treating retroviral infections with benzodiazepine compounds
US5141735A (en) * 1990-06-18 1992-08-25 Hoffman-La Roche, Inc. Substituted amino-benzodiazepines having anitviral activity
EP0491218A1 (en) * 1990-12-17 1992-06-24 F. Hoffmann-La Roche Ag Benzodiazepinones
JPH06501502A (ja) * 1992-02-26 1994-02-17 エフ・ホフマン−ラ ロシユ アーゲー ベンゾジアゼピノン類
SI9300288A (sl) 1992-06-16 1993-12-31 Hoffmann La Roche Benzodiazepini
US5641773A (en) * 1993-11-30 1997-06-24 Dana-Farber Cancer Institute Methods for treating viral infections
WO2002098865A2 (fr) * 2001-06-07 2002-12-12 Neuro3D Inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations de ces inhibiteurs
DE10161767A1 (de) * 2001-12-15 2003-06-26 Merck Patent Gmbh 2-Guanidino-4-heterocyclyl-chinazoline
EP2685985B1 (en) 2011-03-17 2016-08-31 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Methods for treating leukemia and disorders mediated by cbf and runx1 proteins
WO2018093797A1 (en) 2016-11-15 2018-05-24 The Schepens Eye Research Institute, Inc. Compositions and methods for the treatment of aberrant angiogenesis
US11583497B2 (en) 2017-11-14 2023-02-21 The Schepens Eye Research Institute, Inc. Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery
CA3082643A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition
CN107903244B (zh) * 2017-11-29 2019-06-14 武汉珈创生物技术股份有限公司 具有抗肿瘤活性的2-胺基取代苯并二氮卓化合物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2928837A (en) * 1960-03-15 Chj-chj
US2998421A (en) * 1961-08-29 Guanroevo compounds and method of
US2997479A (en) * 1955-07-01 1961-08-22 Endo Lab 1, 1-diphenyl-1-hydroxy-4-(pyrrolidyl)-butanone-2
US2962503A (en) * 1956-11-21 1960-11-29 American Cyanamid Co Nitropyrroles
US2944056A (en) * 1957-05-22 1960-07-05 Sumitomo Chemical Co Method of producing quinazoline derivatives
CH370076A (de) * 1959-01-09 1963-06-30 Cilag Chemie Aktiengesellschaf Verfahren zur Herstellung neuer jodierter Säureamide
US2993905A (en) * 1959-04-24 1961-07-25 Us Vitamin Pharm Corp Nu-dialkylaminoalkyl, nu-pyridylethyl anilines
US2999091A (en) * 1959-10-23 1961-09-05 Abbott Lab 3,9-diazabicyclo[4.2.1]nonane derivatives
US3336295A (en) * 1960-12-02 1967-08-15 Hoffmann La Roche Hydroxy or alkoxy substituted 5-phenyl-3h-1, 4-benzodiazepin-2(1h)-ones

Also Published As

Publication number Publication date
US3400128A (en) 1968-09-03
NL122319C (es)
FR1978M (fr) 1963-08-19
US3100770A (en) 1963-08-13
SE301811B (es) 1968-06-24
GB948888A (en) 1964-02-05
NL131733C (es)
NL6700180A (es) 1967-03-28
US3407211A (en) 1968-10-22
SE343060B (es) 1972-02-28
SE317682B (es) 1969-11-24
US3405122A (en) 1968-10-08
CH445502A (de) 1967-10-31
CH445501A (de) 1967-10-31
SE303752B (es) 1968-09-09
CH450438A (de) 1968-01-31
DE1445862A1 (de) 1969-01-30
US3398159A (en) 1968-08-20
CH425808A (de) 1966-12-15

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