NL2013091B1 - Body worn measurement device. - Google Patents

Body worn measurement device. Download PDF

Info

Publication number
NL2013091B1
NL2013091B1 NL2013091A NL2013091A NL2013091B1 NL 2013091 B1 NL2013091 B1 NL 2013091B1 NL 2013091 A NL2013091 A NL 2013091A NL 2013091 A NL2013091 A NL 2013091A NL 2013091 B1 NL2013091 B1 NL 2013091B1
Authority
NL
Netherlands
Prior art keywords
light
signal
user
amplitude
received
Prior art date
Application number
NL2013091A
Other languages
Dutch (nl)
Inventor
Franciscus Schilthuizen Stephanus
Original Assignee
Scint B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scint B V filed Critical Scint B V
Priority to NL2013091A priority Critical patent/NL2013091B1/en
Priority to US15/322,924 priority patent/US20170172476A1/en
Priority to EP15736679.0A priority patent/EP3160337B1/en
Priority to PCT/NL2015/050468 priority patent/WO2016003269A1/en
Application granted granted Critical
Publication of NL2013091B1 publication Critical patent/NL2013091B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Physiology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Method and device for measuring a signal representative of a physiological parameter of a user. A body worn device includes a securing band and at least one sensor for measuring the signal. The sensor is arranged on the securing band of the device such that when worn, the at least one sensor abuts against the body of the user. A value of the signal is measured using the sensor. An amplitude envelope control band is defined having an envelope upper amplitude value and an envelope lower amplitude value. The amplitude of the measured value is controlled to be within the amplitude envelope control band by controlling a force pressing the at least one sensor in a direction substantially perpendicular to the body of the user.

Description

Title: Body worn measurement device
TECHNICAL FIELD
The invention relates to a measurement device worn on the body and a method for performing a measurement using such device.
BACKGROUND
Body worn devices for measuring a (signal representative of a) physiological parameter of a user are known in the art. Unfortunately, such devices may be unreliable, and sometimes measure a value of the physiological parameter that does not correspond to the actual value of that parameter of the user. These problems can be exacerbated while attempting to measure a physiological parameter of a user during exercise and/or during movements of the skin, body and arms in general. The effect of the exercises, skin, body fluids and body and body part movements on the measurements is for many know devices today that these are not reliable and are largely influenced by (motion) artefacts.
SUMMARY OF THE INVENTION
It is an object of the invention to provide a more reliable device and method for measuring a signal representative of a physiological parameter of a user.
Thereto, according to the invention a method for measuring a signal representative of a physiological parameter of a user is provided comprising the steps of: providing a device worn on a body of the user, wherein the device includes, a securing band, at least one sensor for, preferably non-invasively, measuring the signal representative of the physiological parameter; wherein the at least one sensor is arranged on the securing band of the device such that when worn, the at least one sensor abuts against the body of the user. The method includes performing a measurement session including; measuring a value of the signal using the at least one sensor; defining an amplitude envelope control band having an envelope upper amplitude value and an envelope lower amplitude value, and controlling the amplitude of the measured value to be within the amplitude envelope control band by actively controlling and adjusting a force pressing the at least one sensor in a direction substantially perpendicular to skin or the body of the user.
Further, according to the invention a body worn device for measuring a signal representative of a physiological parameter value is provided. The device comprises a securing band or strap, a control unit, a processing unit, an actuator, and at least one sensor for measuring the signal representative of the physiological parameter value. The at least one sensor is arranged on the securing band of the body worn device such that when worn the at least one sensor abuts against the body of a user. The actuator is arranged for exerting a force on the at least one sensor in a direction substantially perpendicular to the body of the user. The processing unit is arranged for determining an amplitude envelope of the measured signal value. The processing unit has defined therein an amplitude envelope control band having an envelope upper amplitude value and an envelope lower amplitude value. The control unit is arranged for controlling the force exerted by the actuator such that the measured signal value is, e.g. will be and stays, within the amplitude envelope control band.
According to an aspect of the invention a method for measuring a health status of a user is provided comprising the steps of: providing a device worn on a wrist of the user, wherein the device includes, a securing band or strap, at least one light source having a light emitting surface and at least one fight receiver having a fight receiving surface. The at least one fight source and the at least one fight receiver are arranged on the securing band of the device such that when worn, the at least one fight emitting surface and the at least one light receiving surface substantially abut against the palmar side of the wrist of the user, e.g. over one or both of the main arteries (radial and ulnar artery) within the wrist, or on a higher position on the forearm or upper arm or on the finger. The method includes performing a measurement session including; emitting light in a wavelength range by the at least one light source for a predetermined amount of time; producing a received light signal by the at least one light receiver corresponding to a received intensity of fight received at the at least one fight receiver; defining an amplitude envelope control band having an envelope upper amplitude value and an envelope lower amplitude value, and controlling the amplitude of the received light signal to be within the amplitude envelope control band by controlling a force pressing the at least one fight emitting surface and/or at least one fight receiving surface in a direction substantially perpendicular to the palmar side of the user’s wrist. The controlling can include maintaining the amplitude of the received fight signal within the amplitude envelope control band.
The amplitude envelope control band defines a desired amplitude range for the received fight signal taking into account the expected health status of the user and/or any motion artefacts due to the movement of the body and limbs of the user and/or the movement of device on the skin and/or the flow of blood in the arteries and other blood vessels due to the physical movement and position of limbs. If the amplitude of the received fight signal is outside of, or close to the edge of, the amplitude envelope control band, the amplitude of the received fight signal is controlled to be within the amplitude envelope control band by controlling the force pressing the at least one fight emitting surface and/or at least one fight receiving surface in a direction substantially perpendicular to the palmar side of the user’s wrist. In this way the radiative flux into the palmar side of the wrist and/or the radiative flux out of the palmar side of the wrist is controlled.
It will be appreciated that controlling the amplitude of the received light signal to be within the amphtude envelope control band imphes making a best effort at maintaining the amphtude of the received light signal in the amphtude envelope. It is conceivable that the amphtude of the received hght signal departs from the amphtude envelope control band while performing the method. For instance a temporary overshoot is known in control mechanisms. Controlling the force pressing the at least one hght emitting surface and/or at least one hght receiving surface brings the amphtude of the received hght signal back within the amphtude envelope control band.
Controlhng the received hght signal to be within the amphtude envelope control band results in better and more rehable measurements derived from the received hght signal.
Additionally, it will be appreciated that a health status can include a general fitness, heart rate measurement and derivates thereof such as heart rate variability value which is directly related to levels of stress, heart rate recovery rate value which is related to a general fitness or physical health condition, the oxygen saturation rate within the blood which can be measured by using two hght sources with different wavelengths, the respiration rate on basis of the periodic fluctuation of the heart rate signal, the CO2 saturation rate in venous blood, arteries and in other blood vessels, the blood pressure and/or a compliance to an exercise schedule of a user.
Additionally it will be appreciated that the controlhng mechanism can also be combined with another type of sensor, such as an electrically conductive patches, to measure ECG, EEG or EMG signals. An embodiment of the invention can be a band around the upper arm with two integrated ECG electrodes which can pressed on the skin more when the derived electro potential signal is too weak or too much distorted by skin and body movements. This can also be in the shape of an ECG-chest strap or ECG-shirt.
Optionally, the controlling includes decreasing the force when the amplitude of the received light signal exceeds the envelope upper amplitude value and increasing the force when the amplitude of the received light signal is below the envelope lower amplitude value. It has been found that when the amplitude of the received light signal exceeds the envelope upper amplitude value, the radiative flux into and/or out of the palmar side of the wrist should be decreased. This can be achieved by decreasing the force pressing on the at least one light emitting surface and/or the at least one light receiving surface. Similarly, it has been found that when the amplitude of the received light signal is below the envelope lower amplitude value, the radiative flux into and/or out of the palmar side of the wrist should be increased. This can be achieved by increasing the force pressing on the at least one light emitting surface and/or the at least one light receiving surface.
Optionally, the method further includes controlling the amplitude of the received light signal to be within the amplitude envelope control band by controlling an emitted intensity of light emitted by the at least one light source. It is conceivable that in order to better control the amplitude of the received light signal to be within the amplitude envelope control band, that in additional to the pressing force, the emitted intensity of light emitted by the at least one light source is controlled. The emitted intensity of light emitted by the at least one light source can be measured as radiant emittance or radiant excitance measured as power per unit area radiated by a surface.
Optionally, the method includes determining the amplitude envelope control band by measuring the received light signal during a predetermined period, and determining the envelope upper amplitude value and envelope lower amplitude value on the basis of the measured received light signal during the predetermined period. It is also possible that the amplitude envelope control band is predetermined, or selected from a series of predetermined amplitude control bands.
Optionally, the step of determining the amplitude envelope control band is performed at the start of the measurement session. In this way the amplitude envelope control band corresponds to the conditions present at the beginning of the measurement session.
Optionally, the step of determining the amplitude envelope control band is repeated at a plurality of moments during the measurement session so as to set a new amplitude envelope control band during the measurement session. In this way the amplitude control band is set to correspond to changing conditions during the measurement session. Optionally, the step of determining the amplitude envelope control band is performed continuously during the measurement session.
Optionally, the method further includes determining a relationship between the pressing force and the received light intensity depending on the anatomy, skin type, position of arteries etc. This relationship may be used in the step or steps of controlling the amplitude of the received light signal to be within the amplitude envelope control band. The relationship may be used as a transfer function for determining a required amount of change in the pressing force to achieve a desired amount of change in the amphtude of the received light signal.
Optionally, the method further includes applying a step in the force pressing the at least one light emitting surface and/or at least one light receiving surface in a direction substantially perpendicular to the palmar side of the user’s wrist and determining a step response of the received light intensity. The determined step response may be used in the step of controlling the amplitude of the received light signal to be within the amplitude envelope control band.
Optionally, the method further includes determining whether the controlling mechanism should be activated based upon the received light signal, based upon the received light signal and one or more additional sensor signals (pressure sensor and/or accelerometer sensors and/or additional light signals from a different wavelength received by the hght receiver etc.) or based on a received hght signal from an addition hght source with a wavelength which is not able to penetrate the skin deeply and which will show more clearly movement of hght source and hght receiver on the skin (e.g. blue and/or green LED-hght).
Optionally, the method further includes determining the amount of pressing of the controlling mechanism based upon the received hght signal, based upon the received hght signal and one or more additional sensor signals (pressure sensor, accelerometer sensors, additional hght signals from a different wavelength received by the hght receiver etc.) or based on a received hght signal from an addition hght source with a wavelength which is not able to penetrate the skin deeply and which will show more clearly movement of hght source and hght receiver on the skin (e.g. blue and/or green LED-hght).
OptionaUy, the method further includes determining whether the controlling mechanism should be activated, and optionally with what displacement and force, based upon the detection of motion artefacts. This detection of motion artefacts can e.g. include the detection of variation of the received amplitude envelope picked up by a hght receiving surface part. The detection of motion artefacts can also be performed using the above mentioned additional sensors, such as an optical hght receiving sensor, receiving hght of hght emitter surface with a wavelength which doesn’t penetrate the skin easily reflected on the skin, a pressure sensor detecting the contact pressure (and/or force) between the hght emitting and receiving surfaces and the skin, or an accelerometer or combinations of some or all of these additional or already present sensors.
OptionaUy, the method further includes determining the user’s heart rate and/or related parameters such as heart rate variability (‘HRV”) and heart rate recovery rate (“HRR”) and oxygen saturation (“Sp02”), possibly the C02 concentration or saturation rate and the respiration rate on the basis of the received light signal based on time and/or frequency domain analysis, and optionally on the basis of a value of a control signal of the control unit for controlling the force and/or emitted intensity. The high frequency component of the received light signal may also be used.
Optionally, the method further includes performing a first measurement session wherein the light emitted by the at least one light source is in a first wavelength range and performing a second measurement session wherein the light emitted by the at least one light source is in a second wavelength range. Using light in a first wavelength range followed by light in a second wavelength range allows for additional health indicators to be determined.
Optionally, the step of performing a measurement session further includes a step of calculating a perfusion index value on the basis of the received light signals of two fight sources or two fight wavelengths or frequencies of e.g. 600-660 nm and 880-940 nm. Optionally, the method further includes determining the user’s saturation of peripheral oxygen level, Sp02, on the basis of a ratio of the perfusion index value calculated in the first measurement session and the perfusion index value calculated in the second measurement session, and optionally on the basis of a value of a control signal of the control unit for controlling the force and/or emitted intensity. Here the oxygen saturation of the user’s blood and changes in the blood volume in the skin are monitored. The changing absorbance at each of the wavelengths is measured allowing the absorbance due to the pulsing of the blood to be determined. The wrist worn device can act as a plethysmograph, and a photoplethysmogram may be produced and displayed.
The perfusion index valve can be calculated on the basis of a ratio of a high frequency component and a low frequency component of the received light signals.
Optionally, the actuator includes one of a spool and magnet, for example a solenoid or a voice coil, an inflatable body, a piezoelectric actuator, a linear motor, a gear, a conductive polymer or textile structure able to alter it’s dimensions in radial, length and/or width directions when a current is applied or a combination of one or more of these elements.
Optionally, the actuator includes two or more spools and magnets per set of light source and light receiver, for example a solenoid or a voice coil, an inflatable body, a piezoelectric actuator, a linear motor, a gear, a conductive polymer or textile structure able to alter it’s dimensions in radial, length and/or width directions when a current is applied, which make it possible to control the pressing force in two or three orthogonal directions and not only perpendicular to the wrist.
When the controlling mechanism per set of light sources and light receiver consist of a spool and magnet the magnetic fields of these element should be controlled and directed in such a way that the magnets will not be attracted to each other and that the controller doesn’t influence the received light signal. This can e.g. be done e.g. via the use of metal alloys with a high magnetic permeability. Elements of these metals can cover top and bottom of the spool, which has the magnet inside or cover also the outside cylindrical part of the spool.
Another option to overcome this attraction of magnets is to put the magnet in a housing, which has a rigid top and bottom part, which the magnet can’t pass. On top of the magnet a cylindrical, rigid part (e.g. with a diameter smaller than the magnet) can be positioned which slides up and down inside the electrical spool together with magnet during actuation and performs the actual pressing on the skin.
Optionally, the actuator includes a cylindrical magnet with an inner hole in which a spool moves up and down. By this the dimensions of the actuator can be minimized while maintaining of the force to be exerted. Hence, the magnets of each set will not be attracted to each other, while the magnet itself can be mounted and fixed in a polymer casing and is not the moving part. The smaller diameter of this embodiment will enable an array of fight emitting and fight receiving surfaces to be actuated, with reduced power consumption, close to each other in a desired spot at the inner side of the wrist or the arm.
Optionally, the actuator includes a ring or raised areas above the housing of the hollow cylindrical spool and inner magnet or cylindrical hollow magnet and inner spool, which allows the fight emitter and fight receiver surfaces which are initially pressed into the inner, lower area of this ring or raised area after putting on the band/strap of the wrist worn device, to be pushed even further into the skin if necessary or to be released slightly in pressing force to the skin depending on the movement direction of the actuator to achieve the desired signal quality. This ring or raised area, which can have a ring shape which gradually increases from the ground (side of band) to the upper level (contact side with skin) and which can be manufactured of a rigid or slightly deformable material (e.g. rubber or polymer foam, can have a 3-dimensional spacer fabric, deformable by design), can be covered by the inner textile part of the band/strap, which has a small hole in the center area above the ring, to allow the fight emitting and fight receiving surfaces to be pushed slight above or through this hole to enable direct skin contact which is beneficial for an effective fight coupling.
The fight emitting and fight receiving surfaces are preferably positioned close to each other or mounted as bare-die chips on a small flexible or rigid printed circuit board to minimize the required controlling force of the actuator and by this the actuator dimensions and the use of electric power.
The light emitting surfaces are preferably arranged around one or two light receiving surfaces in a position close to each other to maximize the light coupling and light receiving and to minimize the required controlling force of the actuator and by this the actuator dimensions.
The light emitting and light receiving surfaces are preferably covered or moulded into a spherical or half cylindrical shaped polymer material which should be transparent above the light emitting and light receiving surfaces and can be, if necessary for the application, partly less transparent via the use of a coloured pigment additive or completely or partly non-transparent, e.g., grey or black, in the areas between the light emitter and light receiver.
Optionally the actuator can also be used to position and press the light emitting and light receiving surface via an actuator movement more tightly or more loosely in the skin to achieve an optimum signal and to maintain this position during the measurement session.
Optionally, the at least one light source includes a plurality of light sources and at least one light receiver includes a plurality of light receivers, e.g. arranged around (part of) the circumference of the arm or wrist, perpendicular to the arm and/or parallel to the arm and/or in other directions.
The controlling of the signal can also be achieved via the use of a set with at least three or more light emitting surfaces per light receiving surface/sensor, positioned and pressed into the skin area directly above the arteries in the wrist, e.g. the radial artery on the thumb side and the ulnar artery on the smallest fingers side or on another spot of the forearm.
Providing a plurality of light sources and a plurality of light receivers allows for different possibilities of emitting light. Furthermore, with a plurality of receivers the received light signal can be produced in different ways.
Optionally, the step of producing the received light signal at the at least one light receiver includes averaging the received light signals produced at a subset of the plurality of light receivers. Through averaging a more reliable received light signal can be produced.
Optionally, the step of producing the received light signal at the at least one light receiver includes selecting an optimum received light signal produced at one of the light receivers. In this way a received light signal is produced at more than one of the hght receivers, and the optimum received hght signal is selected. The optimum received hght signal may e.g. be the received hght signal having the largest amphtude and/or level. OptionaUy, the optimum received hght signal is selected on the basis of a signal to noise ratio. The optimum received hght signal may e.g. have the largest signal to noise ratio, meaning a distinguishing AC (heart rate pulsation) part above the DC part of the received hght.
OptionaUy, the step of producing the received hght signal at the at least one hght receiver includes selecting the best and second best received signal produced at two of the hght receivers. Additionally, the best and second best received signal may be combined for example by averaging. Herein the best signals may be the signals having the highest level, amphtude and/or signal to noise ratio.
OptionaUy, the method further includes detecting a movement of the user, and or the device on the skin on the basis of the received hght signals, and optionaUy on the basis of a value of a control signal of the control unit for controlling the force and/or emitted intensity. Detecting a movement of the user and or device on the skin can be used to determine the amount or level of artefacts influencing the received signal, to determine if a user is foUowing a prescribed exercise regime, and/or to determine if a user is moving enough to achieve a given health status.
OptionaUy, the step of determining the amphtude envelope of the received hght signal includes filtering the received hght signal, or the square of the received light signal, with at least one of a low pass filter having a cut-off frequency at least less than a highest expected heart rate, preferably substantially equal to 4 Hz, and a bandpass filter having a pass-band defined by the lowest expected heart rate and a highest expected heart rate, preferably substantially equal to 0.7 Hz and 4 Hz.
In this way artefacts arising in the received light signal that correspond to a heart rate outside of the range from the lowest expected heart rate to the highest expected heart rate can removed. The lowest expected heart rate and highest expected heart rate may be predefined. Alternatively, the lowest expected heart rate and the highest expected heart rate may be variable, and may be determined on the basis of the user’s detected movement, a time of day, the user’s age, and/or the user’s sex. The expected heart rate may also be deduced from previous measurements of the user’s heart rate by the device.
Optionally, the step of determining the relationship between the pressing force and the received light intensity is determined for a range of forces exerted on the at least one light source and at least one fight receiver. In this way the step of maintaining the received fight signal in the amplitude envelope control band is facilitated. Optionally, the relationship is stored, for example in a look-up table.
Optionally, the method further comprises a step of selecting the at least one light source from the plurality of light sources and selecting the at least one light receiver from the plurality of light receivers, wherein the step of selecting comprises; for each light source of the plurality of fight sources emitting fight in a wavelength range for a predetermined amount of time; producing at each fight receiver a received fight signal corresponding to the fight received at that fight receiver individually from each fight source; separating each received fight signal into a high frequency component and a low frequency component; calculating for each received fight signal a perfusion index value on the basis of a ratio of the high frequency component and the low frequency component, and selecting a light source and light receiver combination having the highest perfusion index value as the at least one light source and the at least one light receiver.
It has been shown that selecting the light source and light receiver combination having the highest perfusion index value provides an improved received light signal. Different filtering possibilities exist for separating each received light signal into a high frequency component and a low frequency component. The cut-off values frequencies may be based on the lowest expected heart rate and/or the highest expected heart rate.
Optionally, the method includes selecting a subset of light sources of the plurality of light sources and a subset of light receivers of the plurality of light receivers having the highest perfusion index values as the at least one light source and the at least one light receiver. In this way methods of producing the received light signal on the basis of more than one light source and light receiver combination can also be performed.
Optionally, the step of selecting is performed for a first wavelength range and a second wavelength range, and optionally for a third and optionally fourth wavelength range. It is conceivable that different fight source and light receiver combinations are ideal for the first wavelength range and the second wavelength range. It can be advantageous to determine the fight source and fight receiver combination for each range independently.
Optionally, the method further comprises a step of displaying on a display associated with the wrist worn device an instruction instructing and advising the user to perform a predetermined exercise; performing a measurement session while the user performs the predetermined exercise; and storing a result of the measurement session, wherein the result preferably includes the user’s heart rate and/or saturation of peripheral oxygen level and/or ability to recover the user’s heart rate at a normal, nonexercising level, for example heart rate recovery.
In this way, an indication of the user’s health can be determined while performing a predetermined exercise. The display may be included in the wrist worn device. Additionally, or alternatively, the display may be included in an external device, such as a smart phone device, that is wired or wirelessly communicatively connected with the wrist worn device.
Optionally, the method further comprises, measuring the general fitness of the user on the basis of the measurement session and/or previous measurement sessions; displaying an indication of the general fitness and/or health of the user. In this way, the user and/or a health advisor can quickly determine an indication of the user’s general fitness.
Preferably a graphical representation of a person having a general fitness corresponding to the general fitness of the user is displayed. For example if it is determined that the general fitness of the user is poor, the displayed graphical representation of the person may have his hands on his knees and be breathe heavily. On the other hand if the general fitness of the user is good, the displayed graphical representation of the person may be performing jumping jacks, or be jogging in place. Or on the other hand if the oxygen saturation value and or heart rate recovery rate of the user is good, the displayed graphical presentation of the person may be moving faster than if the oxygen saturation value and or heart rate recovery rate of the user is less good, giving an indication of a lower general fitness or deteriorating health condition.
Optionally, the graphical representation moves and is coloured corresponding to the general fitness of the user and/or compliance to the exercise schedule. For example, if the general fitness of the user and exercise compliance is determined to be poor, the displayed graphical representation may be coloured red and or moving slowly in the display. Similarly, if the general fitness of the user and or exercise compliance is determined to be improving, the displayed graphical representation may be coloured orange green and or moving a bit faster in the display than the displayed graphical presentation in red.
Similarly, if the general fitness of the user and/or exercise compliance is determined to be good, the displayed graphical representation may be coloured green and/or moving faster in the display.
Optionally, the graphical representation moves and or is coloured and shaped corresponding to the Body Mass Index of the user and/or compliance to the exercise schedule.
Further, according to the invention a wrist worn device is provided comprising a securing band, a control unit, a processing unit, at least one light source having a light emitting surface and at least one light receiver having a fight receiving surface, an actuator arranged below each fight emitting surface (e.g. below each fight source), and each fight receiving surface (e.g. below each fight receiver), or below each combination of fight emitting and fight receiving surface. The at least one fight source and the at least one fight receiver are arranged on the securing band of the wrist worn device such that when worn the at least one fight emitting surface and the at least one fight receiving surface substantially abut against the palmar side of the wrist of a user. The actuator is arranged for exerting a force on the at least one fight emitting surface and/or at least one fight receiving surface in a direction substantially perpendicular to the palmar side of the user’s wrist. The at least one fight source is arranged for emitting fight in a wavelength range. The at least one fight receiver is arranged for producing a received fight signal corresponding to a received intensity of the fight received at the at least one fight receiving surface. The processing unit is arranged for determining an amplitude envelope of the received fight signal. The processing unit has defined therein an amplitude envelope control band having an envelope upper amplitude value and an envelope lower amplitude value. The control unit is arranged for controlling the force exerted by the actuator such that the received light signal is controlled to be within the amplitude envelope control band.
It has been found that by trying to maintain the received light signal within the amplitude envelope control band an improved received light signal is provided. This signal can be used as the basis for performing measurement and determining a health status of the user.
Optionally, the control unit is arranged for decreasing the force when the amplitude of the received light signal exceeds the envelope upper amplitude value and for increasing the force when the amplitude of the received light signal is below the envelope lower amplitude value. Optionally, the control unit is further arranged for controlling an emitted intensity of light emitted by the at least one light source such that the amplitude of the received light signal is maintained within the amplitude envelope control band.
Optionally, the wrist worn device further including a wireless communication unit arranged for communicating with a communications device, such as a smart phone, with display. In this way, the wrist worn device can take advantage of the smart phone’s processing power, display capabilities, and user interface, e.g. via combined use with a smart phone application (app).
Optionally, the securing band is provided with woven, knitted and/or embroidered electrical connection threads connecting the at least one light source and at least one light receiver with the control unit. The securing band can be adjusted more easily to the dimensions and wrist circumferences differences of various users. Retaining the electrical connection threads in the securing band allows the control unit to be placed remotely from the at least one light emitting surface and at least one light receiving surface and allows the actuator to move without large forces the element containing the light emitting surface and light receiving surface, or the element containing the light source and receiver, and the electrical wires relatively more to the centre of the wrist or further away from the centre of the wrist. This is advantageous as the at least one light receiving surface substantially abut against the palmar side of the wrist of a user.
Optionally, the at least one light source includes an optical fiber for guiding light towards the skin of the user and/or the at least one light receiver includes an optical fiber for guiding light from the skin of the user. Advantageously, the at least one light source and/or the at least one light receiver may be remote from the skin of the user on palmar side of the wrist.
Optionally, the optical fiber is woven in, knitted in and/or embroidered on the securing band. Optionally, the optical fiber of is included in the securing band such that the ends of the fibers are mechanically touching the skin of the user. In this way the band holds the end of the fibers in position for guiding light towards and/or away from the skin of the user.
Optionally, at least a section of the optical fiber that is positioned to mechanically touch the skin of the user has been treated to allow light to couple out and/or in.
Optionally, the wrist worn device includes a plurality of actuators and a plurality of fight sources and a plurality of fight receivers wherein each actuator is arranged for exerting a force on one fight emitting surface and/or fight source and/or one fight receiver and/or fight receiving surface, wherein the control unit is arranged for actuating each actuator independently. Optionally, the wrist worn device includes a plurality of actuators and a plurality of fight sources having a plurality of fight emitting surfaces and a plurality of fight receivers having a plurality of fight receiving surfaces wherein each actuator is arranged for exerting a force on one fight emitting surface and/or one fight receiving surface, wherein the control unit is arranged for actuating each actuator independently.
Optionally, the wrist worn device includes one or more fight sources and fight receivers which can be pressed on the skin more tightly via a passive spring system which is compressed slightly when the band with the light sources and light receivers on the inside is fastened to the skin. This system can be made into a controllable actuator when it’s coupled to a mechanism, which tightens the band more or less based upon received light and possibly other sensor signals.
Actuating each actuator independently allows a force pressing each light emitting surface and each light receiving surface to also be controlled independently. Furthermore, independent control may be advantageous when one a single light source and light receiver is selected, or when a subset of light sources and light receivers are selected. This also applies to hght emitting surfaces and light receiving surfaces. Additionally, due to the wrist of a user and the securing band the hght emitting surfaces and light receiving surfaces of the device may not evenly contact the user’s skin. This may be corrected for by using independently controlled actuators.
Optionally, the hght emitting surface of the at least one hght source and/or the light receiving surface of the at least one hght receiver is covered with a transparent soft polymer cover and surrounded with an elastic frame, of hght blocking non transparent polymer material.
In this way the hght emitted from the hght emitting surface is directed substantially towards the skin of the user. Stray hght emitted from the hght emitting surface is prevented from interfering with other emitting surfaces and from entering the hght receiving surface without travehng through the user. Therefore, crosstalk between hght sources and hght receivers is reduced substantially. Also ambient hght can be blocked by this method, combined with the mechanical force apphed by the fastened securing band.
OptionaUy, the cover is spherically or cyhndrical shaped and is arranged to be pressed inwardly of the palmar part of the wrist by adjusting the securing band and/or the actuator. A spherically shaped or cyhndrical shaped cover or housing of the hght emitting and hght receiving surfaces improves the coupling of light emitted from the light emitting surface into the user, and improves the capture of light traveling out of the user and into the light receiving surface.
Optionally, the processing unit is arranged to detect whether the device is properly worn, or even worn at all, at the wrist on the basis of the received light signal. When the device is worn properly, an expected received light signal can be determined. On the basis of this signal, it can be determined if the received light signal corresponds to a properly worn device.
Optionally, the wrist worn device further includes an accelerometer arranged for detecting the amount of movement of the wrist of the user and/or the device on the wrist of the user. This may provide an indication of the amount of everyday movement of the user. Additionally, or alternatively, this may provide an indication of a user’s compliance to an exercise program or schedule. Furthermore, the output signal of the accelerometer may be provided to the processing unit and/or the control unit for taking the amount of movement of the wrist of the user into account when determining the amplitude envelope control band and/or controlling the force.
Optionally, the processing unit is arranged for determining the blood composition of the user (haemoglobin, haematocrit value) for medical purposes such as blood deficiencies after chemo treatment and/or radiation therapy, blood loss after birth or accidents, infections with tropical diseases such as Denque, dehydration etc.
Further, according to the invention a system including a wrist worn device according to the invention including a wired or wireless communication unit and a communications device such as a display on the wrist worn device and/or on a further device, such as a smart phone, with a display connected to the system.
It will be appreciated that features described with regard to one of the method according to the invention, the wrist worn device according to the invention and the system according to the invention are considered to be disclosed for the remaining categories.
BRIEF DESCRIPTION OF THE DRAWINGS
The invention will now be further elucidated by means of non-limiting examples referring to the drawings, in which
Fig. 1 shows a schematic top view of a wrist worn device according to the invention;
Fig. 2 shows a schematic side view of a wrist worn device according to the invention;
Fig. 3 a shows an example of a measurement of a received light signal while the actuator is active;
Fig. 3b shows an example of a measurement of a received light signal while the actuator is deactivated;
Fig. 4 shows a schematic representation of a system according to the invention including a wrist worn device and a communications device;
Fig. 5 shows the system according to the invention displaying an indication of the general fitness and/or health of a user; and
Fig. 6 shows the system according to the invention displaying an indication of the general fitness and/or health of a user;
DETAILED DESCRIPTION
Fig. 1 shows a schematic top view of a wrist worn device 1 according to the invention, and Fig. 2 shows a schematic side view in the direction of arrows II of Fig. 1. The wrist worn device includes a securing band 2, a control unit 4, a processing unit 6, and an actuator 8. In this example, the device 1 includes three fight sources each having a fight emitting surface 12. In this example, the device 1 also includes three fight receivers having a light receiving surface 16. The light emitting surfaces 12 and the light receiving surfaces 16 are arranged on the securing band 2 of the wrist worn device 1 such that when worn the at least one light emitting surface 12 and the at least one light receiving surface 16 substantially abut against the palmar side of the wrist of a user. Additionally in this embodiment the light emitting surfaces 12 and the light receiving surfaces 16 are separated by a non-transparent light blocker 13, which can extend to the upper surface where there will be contact with the skin. Furthermore, in this example the light emitting surfaces 12 and the light receiving surfaces 16 are received in an elastic frame 10 and 14, respectively, of light blocking material. Finally a spherically shaped transparent polymer cover 26 is provided.
In this example, the actuator 8 includes a spool 18 and a magnet 20. The spool 18 in received in a polymer or non-magnetic housing 22. The polymer housing 22 includes an actuating surface or connector 24. The actuator 8 is arranged for exerting a force on the light emitting surfaces in a direction A substantially perpendicular to the palmar side of the user’s wrist. The user’s wrist is not shown, however it will be clear that the surface of cover 26 of the wrist worn device 1 abuts substantially parallel to the user’s wrist.
The securing band or strap can include one or more sections of stretchable textile materials and or polymer materials enabling a tight securing and delivering an initial pressing force for the actuators and light emitting and hght receiving surfaces. The entire circumference of the securing band or strap can also be made of such material.
The securing band or strap can include a stretchable foam material which is permeable to water vapour, sweat and gasses, allowing ventilation of the skin. Such foam material can on the side abutting the arm or wrist be covered with a textile material allowing absorption and uptake of sweat, regulating the microclimate and preventing allergic reactions. The entire circumference of the securing band or strap can also be made of such foam material. The foam material can on the arm or wrist side be covered with a fine textile material allowing absorption and uptake of sweat, regulating the microchmate and allergic reactions.
The light receivers 16 are arranged for producing a received fight signal corresponding to a received intensity of the fight received at the at least one light receiving surface 16. The processing unit 6 is arranged for determining an amplitude envelope of the received light signal. The processing unit 6 has defined therein an amplitude envelope control band having an envelope upper amplitude value and an envelope lower amplitude value. The control unit 4 is arranged for controlling the force exerted by the actuator 8 such that the received light signal is controlled to be within the amplitude envelope control band. Preferably, the received light signal is maintained within the amplitude envelope control band. In this example this occurs by the control unit 4 controlling the current flow through spool, or coil, 18, which in turn creates a magnetic field and displaces the actuating surface 24 relative to the magnet 20. The displacement of the actuating surface 24 results in an increase or decrease in the pressing force parallel to direction A and, when worn, substantially perpendicular to the user’s wrist.
During a measurement session the amplitude of the received fight signal is kept within the amplitude envelope control band. Measurements derived from a received fight signal where the amplitude of the received fight signal has been kept within the amplitude envelope control band during a measurement session are more reliable. In this example, a user’s heart rate and heart rate variability are determined on the basis of the received fight signal. Figure 3a shows an example of a measurement of the received fight signal as a function of time while the actuator 8 is active to control the signal to be within the amplitude envelope control band. The heart beats are clearly visible in Fig. 3a. Figure 3b shows an example of a measurement of the received light signal as a function of time while the actuator 8 is deactivated. The difference with Fig. 3a is big, and all individual heartbeats cannot be identified in the measured signal in Fig. 3b, which is disturbed largely by the motion artefacts (movement of fight emitters and receivers on skin, movement of limbs, flow of blood).
Additionally, in this example the three fight emitting sources are each capable of emitting fight in a first wavelength range and a second wavelength range. In this example, each fight source comprises a first LED capable of emitting fight in a first wavelength range of 600-660 nm and a second LED capable of emitting fight in a second wavelength range of 880-940 nm, or in wavelengths, which are capable of detection of other gases, solids or liquids in the blood (e.g. 700-900 nm for CO2)
By performing a first measurement session wherein the fight emitted by the three fight sources in the first wavelength range and performing a second measurement session wherein the fight emitted by the three fight sources is in the second wavelength range additional health indicators such as the user’s saturation of peripheral oxygen level, Sp02, can be determined. This is determined on the basis of a ratio of the perfusion index value calculated in the first measurement session and the perfusion index value calculated in the second measurement session.
In this example, prior to performing a measurement session a selection step is performed. In the selection step a fight source and fight receiver combination is selected. For each fight source of the three fight sources, fight is emitted in a wavelength range for a predetermined amount of time. A received fight signal is produced at each of the fight receivers. The processing unit 6 separates each received fight signal into a high frequency component and a low frequency component using filters with cut-off frequency values that are based on the lowest expected heart rate and the highest expected heart rate. A perfusion index value is calculated for each received fight signal by the processing unit 6 on the basis of a ratio of the high frequency component and the low frequency component. The steps are repeated for each light source, and the light source and light receiver combination having the highest perfusion index value is selected. It is possible that after this selection the non-selected light sources are switched off to reduce power consumption. A system 100 including a wrist worn device 1 and a communications device 50 is shown in Fig. 4. The communications device 50 includes a display, e.g. a touch screen display, 52, which gives information, feedback and instructions to the user and which software application can also be used to define, start and install measurement sessions. In this example, the display 52 is associated with the wrist worn device. Additionally both the communications device 50 and the wrist worn device 1 include a communication unit, not pictured, through which the devices are able to communicate with each other. In this example the communications and controlling device 50 can for instance be a smart phone device with a touch screen display.
With the system 100, a user can monitor his general fitness. In addition, a user and/or a health advisor can monitor a user’s compliance to a selected exercise schedule. For example, in Fig. 5, an exercise instruction 54 appears on the display 52 of the communications device 50. For example, the instruction 54 instructs the user to perform e.g. twenty knee bendings (so called squats). During the exercise a measurement session is performed. Preferably, a measurement session is performed prior to starting the exercise and, e.g. at predefined intervals, after the exercise is completed. It is possible that the wrist worn device 1 concludes that the exercise is completed on the basis of at least one of an amount of movement determined on the basis of the received light signal, an amount of movement determined by an accelerometer of the wrist worn device, and a measured elapsed time interval.
In this case during each measurement session the user’s heart rate, heart rate variability, and Sp02 is measured. On the basis of these measurements recorded during different measurement sessions, an indication of a user’s general fitness and/or indication of the user’s health is determined.
On the display 52 of communications device 50 associated with the wrist worn device 1, an indication 56 of the general fitness of the user is displayed. The indication 56 may relate to the general fitness just measured during the exercise. Additionally, or alternatively, the indication 56 may relate to a general fitness measured on the basis of the measurement session and one or more previous measurement sessions, for example measurement sessions taken over the previous week or month.
In this example, the indication 56 is a graphical representation of a person having a general fitness corresponding to the general fitness of the user. In Fig. 5, the measured general fitness of the user is poor. Therefore a graphical representation 56 of a person having a poor general fitness is shown. In this example, the graphical representation 56 is of an overweight person. Additionally, in the case that the graphical representation 56 of the person is animated, the animation can represent the general fitness of the user, e.g. graphical representation 56 of the person can be animated to be breathing heavily.
In Fig. 6, the measured general fitness of the user is good. Therefore a graphical representation 56 of a person having a good general fitness is shown. The graphical representation 56 is a of healthy person of normal build. Additionally, in the case that the graphical representation 56 of the person is animated, the graphical representation 56 of the person can e.g. be moving fast or running in place.
The indication 56 of a general fitness of the user can also be measured on the basis of measurement session initiated in response to an amount of movement being detected by the accelerometers provided, not pictured, in the wrist worn device. The amount of movement and the measured health status are recorded in the wrist worn device 1 and/or the communications device 50. In this way a measure of compliance to an exercise schedule is measured. For example, the schedule might require that the user performs 30 minutes of exercise a day at or above the users target heart rate. In the case of Fig. 6, the user has achieved a 90 % compliance. In the example of Fig. 6 this is displayed as a text 58, including an encouraging comment, on display 52 of the communications device 50 or a changing colour of the graphical presentation of a person or higher moving speed of the graphical presentation of a person.
In the foregoing specification, the invention has been described with reference to specific examples of embodiments of the invention. It will, however, be evident that various modifications and changes may be made therein without departing from the broader spirit and scope of the invention as set forth in the appended claims. For the purpose of clarity and a concise description features are described herein as part of the same or separate embodiments, however, alternative embodiments having combinations of all or some of the features described in these separate embodiments are also envisaged.
However, other modifications, variations, and alternatives are also possible. The specifications, drawings and examples are, accordingly, to be regarded in an illustrative rather than in a restrictive sense.
For the purpose of clarity and a concise description features are described herein as part of the same or separate embodiments, however, it will be appreciated that the scope of the invention may include embodiments having combinations of all or some of the features described.
In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The word ‘comprising’ does not exclude the presence of other features or steps than those listed in a claim.
Furthermore, the words ‘a’ and ‘an’ shall not be construed as limited to ‘only one’, but instead are used to mean ‘at least one’, and do not exclude a plurality. The mere fact that certain measures are recited in mutually different claims does not indicate that a combination of these measures cannot be used to advantage.

Claims (44)

1. Werkwijze voor het meten van een signaal dat representatief is voor een fysiologische parameter van een gebruiker omvattende de stappen: het verschaffen van een op een lichaam van de gebruiker gedragen inrichting, waarbij de inrichting een bevestigingsband, ten minste een sensor voor het meten van het signaal dat representatief is voor de fysiologische parameter omvat; waarbij de ten minste ene sensor is geplaatst op de bevestigingsband van de inrichting zodanig dat wanneer gedragen de ten minste ene sensor aanligt tegen het lichaam van de gebruiker; en het uitvoeren van een meetsessie omvattende: het meten van een waarde van het signaal gebruikmakend van de ten minste ene sensor; het definiëren van een amplituderegelband met een enveloppe-boven-amplitudewaarde en een enveloppe-onder-amplitudewaarde, en het regelen van de amplitude van de gemeten waarde om binnen de amplituder e gelb an d te liggen door het regelen van een kracht die de ten minste ene sensor in een richting in hoofdzaak loodrecht op het lichaam van de gebruiker drukt.A method for measuring a signal representative of a physiological parameter of a user comprising the steps of: providing a device supported on a body of the user, the device comprising a mounting tape, at least one sensor for measuring comprises the signal representative of the physiological parameter; wherein the at least one sensor is placed on the mounting strap of the device such that when worn the at least one sensor abuts the body of the user; and performing a measurement session comprising: measuring a value of the signal using the at least one sensor; defining an amplitude control band with an envelope-above-amplitude value and an envelope-below-amplitude value, and controlling the amplitude of the measured value to lie within the amplitude and controlling a force that is at least one sensor in a direction substantially perpendicular to the body of the user. 2. Werkwijze volgens conclusie 1, waarbij het regelen omvat het verminderen van de kracht wanneer de amplitude van het ontvangen signaal de enveloppe-boven-amplitudewaarde overschrijdt en het vergroten van de kracht wanneer de amplitude van het ontvangen signaal onder de enveloppe-onder-amplitudewaarde is.The method of claim 1, wherein the controlling comprises reducing the force when the amplitude of the received signal exceeds the envelope-upper-amplitude value and increasing the force when the amplitude of the received signal below the envelope-below-amplitude value is. 3. Werkwijze volgens conclusie 1 of 2, waarbij de sensor een lichtbron omvat met een lichtuitzendvlak en ten minste een lichtontvanger met een lichtontvangvlak; waarbij de ten minste ene lichtbron en de ten minste ene lichtontvanger zijn geplaatst op de bevestigingsband van de inrichting, zodanig dat wanneer gedragen het ten minste ene lichtuitzendvlak en het ten minste ene lichtontvangvlak in hoofdzaak aanliggen tegen de paknaire zijde van de pols van de gebruiker; en waarbij de stap van het meten van het signaal omvat: het uitzenden van licht in een golfiengtebereik door de ten minste ene lichtbron voor een vooraf bepaalde hoeveelheid tijd; het produceren van een ontvangen lichtsignaal door de ten minste ene lichtontvanger corresponderend met een ontvangen lichtintensiteit ontvangen aan de ten minste ene lichtontvanger; en waarbij de stap van het regelen omvat het regelen van de amplitude van het ontvangen lichtsignaal om binnen de amplitude-enveloppe-regelband te zijn door het regelen van een kracht die het ten minste ene lichtuitzendvlak en/of het ten minste ene lichtontvangvlak in een richting in hoofdzaak loodrecht op de palmaire zijde van de gebruikers pols drukt.The method of claim 1 or 2, wherein the sensor comprises a light source with a light emitting surface and at least one light receiver with a light receiving surface; wherein the at least one light source and the at least one light receiver are placed on the mounting strap of the device such that when worn, the at least one light emitting surface and the at least one light receiving surface substantially abut the wearer's side of the user's wrist; and wherein the step of measuring the signal comprises: emitting light in a wave length range from the at least one light source for a predetermined amount of time; producing a received light signal by the at least one light receiver corresponding to a received light intensity received at the at least one light receiver; and wherein the step of controlling comprises controlling the amplitude of the received light signal to be within the amplitude envelope control band by controlling a force that directs the at least one light emitting surface and / or the at least one light receiving surface in one direction substantially perpendicular to the palmar side of the user's wrist. 4. Werkwijze volgens conclusie 3, voorts omvattende het regelen van de amplitude van het ontvangen lichtsignaal om binnen de amplitude-enveloppe-regelband te zijn door het regelen van een uitgezonden intensiteit van licht uitgezonden door de ten minste ene lichtbron.The method of claim 3, further comprising controlling the amplitude of the received light signal to be within the amplitude envelope control band by controlling a transmitted intensity of light emitted from the at least one light source. 5. Werkwijze volgens een der voorgaande conclusies, omvattende het bepalen van de amplitude-enveloppe-regelband door het meten van het signaal gedurende een vooraf bepaalde periode, en het bepalen van de enveloppe-boven-amplitudewaarde en de enveloppe-onder-amplitudewaarde op basis van de gemeten waarde gedurende de vooraf bepaalde periode.A method according to any one of the preceding claims, comprising determining the amplitude envelope control band by measuring the signal for a predetermined period, and determining the envelope-above-amplitude value and the envelope-below-amplitude value based on of the measured value during the predetermined period. 6. Werkwijze volgens conclusie 5, waarbij de stap van het bepalen van de amplitude-enveloppe-regelband wordt uitgevoerd aan het begin van de meetsessie.The method of claim 5, wherein the step of determining the amplitude envelope control band is performed at the beginning of the measurement session. 7. Werkwijze volgens conclusie 5 of 6, waarbij de stap van het bepalen van de amplitude-enveloppe-regelband wordt herhaald op momenten gedurende de meetsessie om een nieuwe amplitude-enveloppe-regelband in te stellen gedurende de meetsessie.The method of claim 5 or 6, wherein the step of determining the amplitude envelope control band is repeated at times during the measurement session to set a new amplitude envelope control band during the measurement session. 8. Werkwijze volgens conclusie 5, 6 of 7, waarbij de stap van het bepalen van de amplitude-enveloppe-regelband continu wordt uitgevoerd gedurende de meetsessie.A method according to claim 5, 6 or 7, wherein the step of determining the amplitude envelope control band is performed continuously during the measurement session. 9. Werkwijze volgens een der voorgaande conclusies, voorts omvattende het bepalen van een relatie tussen de aandrukkracht en de gemeten waarde.A method according to any one of the preceding claims, further comprising determining a relationship between the pressure force and the measured value. 10. Werkwijze volgens conclusie 9, omvattende het aanbrengen van een stap in de kracht die de ten minste ene sensor in de richting in hoofdzaak loodrecht op de gebruiker’s lichaam drukt en een staprespons bepalen van het gemeten signaal.The method of claim 9, including applying a step in the force that presses the at least one sensor in the direction substantially perpendicular to the user's body and determining a step response of the measured signal. 11. Werkwijze volgens een der voorgaande conclusies voor zover afhankelijk van conclusie 3, voorts omvattende het bepalen van de gebruiker’s hartritme op basis van het ontvangen lichtsignaal op basis van tijd- en/of frequentiedomein analyse, en optioneel op basis van een waarde van een regelsignaal van de regeleenheid voor het regelen van de kracht e/of uitgezonden intensiteit.A method according to any one of the preceding claims insofar as dependent on claim 3, further comprising determining the user's heart rhythm based on the received light signal based on time and / or frequency domain analysis, and optionally based on a value of a control signal of the control unit for controlling the force and / or transmitted intensity. 12. Werkwijze volgens een der voorgaande conclusies voor zover afhankelijk van conclusie 3, voorts omvattende het uitvoeren van een eerste meetsessie waarbij het door de ten minste ene lichtbron uitgezonden licht in een eerste golflengtebereik is en het uitvoeren van een tweede meetsessie waarbij het door de ten minste ene lichtbron uitgezonden licht in een tweede golflengtebereik is.A method according to any one of the preceding claims insofar as dependent on claim 3, further comprising performing a first measurement session wherein the light emitted from the at least one light source is in a first wavelength range and performing a second measurement session wherein the at least one least one light source is light emitted in a second wavelength range. 13. Werkwijze volgens conclusie 12, waarbij de stap van het uitvoeren van een meetsessie voorts een stap omvat van het berekenen van een perfusieindexwaarde op basis van het ontvangen lichtsignaal; en waarbij de werkwijze voorts omvat het bepalen van de gebruiker’s zuurstofsaturatiewaarde op basis van een ratio van de perfusieindexwaarde berekend in de eerste meetsessie en de perfusieindexwaarde berekend in de tweede meetsessie, en optioneel op basis van een waarde van een regelsignaal van de regeleenheid voor het regelen van de kracht en/of uitgezonden lichtintensiteit.The method of claim 12, wherein the step of performing a measurement session further comprises a step of calculating a perfusion index value based on the received light signal; and wherein the method further comprises determining the user's oxygen saturation value based on a ratio of the perfusion index value calculated in the first measurement session and the perfusion index value calculated in the second measurement session, and optionally based on a value of a control signal from the control unit for controlling of the power and / or transmitted light intensity. 14. Werkwijze volgens een der voorgaande conclusies, waarbij de actuator een omvat van een spoel en magneet, een opblaasbaar lichaam, een piëzoelektrische actuator, en lineaire motor, een overbrenging, een geleidende polymeer of textielstructuur ingericht om zijn dimensies in radiale, lengte-en/of breedterichting te veranderen wanneer een stroom wordt aangebracht.A method according to any one of the preceding claims, wherein the actuator comprises a coil and magnet, an inflatable body, a piezoelectric actuator, and a linear motor, a transmission, a conductive polymer or textile structure adapted to its dimensions in radial, length, and / or change the width direction when a current is applied. 15. Werkwijze volgens een der voorgaande conclusies voor zover afhankelijk van conclusie 3, waarbij de ten minste ene lichtbron een veelvoud van lichtbronnen omvat en de ten minste ene lichtontvanger een veelvoud van lichtontvan gers.A method according to any one of the preceding claims as far as dependent on claim 3, wherein the at least one light source comprises a plurality of light sources and the at least one light receiver a plurality of light receivers. 16. Werkwijze volgens conclusie 15, waarbij de stap van het produceren van het ontvangen lichtsignaal aan de ten minste ene ontvanger omvat het middelen van de ontvangen lichtsignalen geproduceerd aan een subset van het veelvoud van lichtontvangers.The method of claim 15, wherein the step of producing the received light signal to the at least one receiver comprises averaging the received light signals produced to a subset of the plurality of light receivers. 17. Werkwijze volgens conclusie 15, waarbij de stap van het produceren van het ontvangen lichtsignaal aan de ten minste ene lichtontvanger omvat het selecteren van een optimaal ontvangen lichtsignaal geproduceerd aan een van de lichtontvangers.The method of claim 15, wherein the step of producing the received light signal at the at least one light receiver comprises selecting an optimally received light signal produced at one of the light receivers. 18. Werkwijze volgens conclusie 15, waarbij de stap van het produceren van het ontvangen lichtsignaal aan de ten minste ene lichtontvanger omvat het selecteren van het beste een tweede beste ontvangen lichtsignaal geproduceerd aan twee van de lichtontvangers.The method of claim 15, wherein the step of producing the received light signal at the at least one light receiver comprises selecting the best and a second best received light signal produced at two of the light receivers. 19. Werkwijze volgens een der voorgaande conclusies, voorts omvattende het detecteren van een beweging van de gebruiker op basis van het signaal, en optioneel op basis van een regelsignaal van de regeleenheid voor het regelen van de kracht en/of uitgezonden intensiteit.A method according to any one of the preceding claims, further comprising detecting a movement of the user based on the signal, and optionally based on a control signal from the control unit for controlling the force and / or transmitted intensity. 20. Werkwijze volgens een der voorgaande conclusies voor zover afhankelijk van conclusie 3, waarbij de stap van het bepalen van de amplitude-enveloppe van het ontvangen lichtsignaal omvat het filteren van het ontvangen lichtsignaal met ten minste een van een laagdoorlaatfilter met een afsnijfrequentie die ten minste lager is dan een hoogste verwachte hartfrequentie, bij voorkeur gelijk aan 4 Hz, en een banddoorlaatfilter met een doorlaatband gedefinieerd door de laagst verwachte hartfrequentie en een hoogst verwachte hartfrequentie, bij voorkeur gelijk aan 0.7 Hz en 4 Hz.A method according to any one of the preceding claims as far as dependent on claim 3, wherein the step of determining the amplitude envelope of the received light signal comprises filtering the received light signal with at least one of a low-pass filter having a cut-off frequency which is at least is lower than a highest expected heart rate, preferably equal to 4 Hz, and a band pass filter with a pass band defined by the lowest expected heart rate and a highest expected heart rate, preferably equal to 0.7 Hz and 4 Hz. 21. Werkwijze volgens conclusie 9 of 10, waarbij de stap van het bepalen van de relatie tussen de aandrukkracht en de gemeten signaalwaarde wordt bepaald voor een bereik aan krachten uitgeoefend op de ten minste ene sensor.A method according to claim 9 or 10, wherein the step of determining the relationship between the pressure force and the measured signal value is determined for a range of forces exerted on the at least one sensor. 22. Werkwijze volgens conclusie 9, 10 of 21, voorts omvattende het opslaan van de relatie.The method of claim 9, 10 or 21, further comprising storing the relationship. 23. Werkwijze volgens conclusie 17, voorts omvattende een stap van het selecteren van de ten minste ene lichtbron van het veelvoud van lichtbronnen en het selecteren van ten minste ene lichtontvanger van het veelvoud van lichtontvangers, waarbij de stap van het selecteren omvat: voor elke lichtbron van het veelvoud van lichtbronnen gedurende een vooraf bepaalde tijdsperiode licht uitzenden in een golflengtebereik; individueel voor elke lichtontvanger produceren aan elke lichtontvanger een ontvangen lichtsignaal corresponderend met het licht ontvangen aan die lichtontvanger; scheiden van elk ontvangen lichtsignaal in een hoogfrequente component en een laagfrequente component; berekenen voor elk ontvangen lichtsignaal een perfusieindexwaarde op basis van een verhouding van de hoogfrequente component en de laagfrequente component, en het selecteren van een lichtbron en lichtontvanger combinatie met de hoogste perfusieindexwaarde as de ten minste ene lichtbron en de ten minste ene lichtontvanger.The method of claim 17, further comprising a step of selecting the at least one light source from the plurality of light sources and selecting at least one light receiver from the plurality of light receivers, the step of selecting comprising: for each light source of the plurality of light sources emitting light in a wavelength range during a predetermined period of time; individually for each light receiver, produce to each light receiver a received light signal corresponding to the light received at that light receiver; separating each received light signal into a high-frequency component and a low-frequency component; calculate for each received light signal a perfusion index value based on a ratio of the high-frequency component and the low-frequency component, and selecting a light source and light receiver combination with the highest perfusion index value as the at least one light source and the at least one light receiver. 24. Werkwijze volgens conclusie 23, voorts omvattende het selecteren van een subset van lichtbronnen van het veelvoud van hchtbronnen en een subset van hchtontvangers van het veelvoud van hchtontvangers met de hoogste perfusieindexwaarden als de ten minste ene lichtbron en de ten minste ene lichtontvanger.The method of claim 23, further comprising selecting a subset of light sources from the plurality of hold sources and a subset of hold receivers from the plurality of hold receivers with the highest perfusion index values as the at least one light source and the at least one light receiver. 25. Werkwijze volgens conclusie 23 of 24, waarbij de stap van het selecteren wordt uitgevoerd voor en eerste golflen gteb er eik en een tweede golflengtebereik.The method of claim 23 or 24, wherein the step of selecting is performed for a first wave length each and a second wavelength range. 26. Werkwijze volgens een der voorgaande conclusies, voorts omvattende een stap van het weergeven op een display geassocieerd met de inrichting een instructie die de gebruiker instrueert om een vooraf bepaalde oefening uit te voeren; het uitvoeren van een meetsessie terwijl de gebruiker de vooraf bepaalde oefening uitvoert, en het opslaan van een resultaat van de meetsessie, waarbij het resultaat bij voorkeur omvat de gebruiker’s hartritme en/of zuurstofsaturatie en/of vermogen om de gebruiker’s hartritme op een normaal, niet-oefenenend niveau terug te brengen.The method of any one of the preceding claims, further comprising a step of displaying on a display associated with the device an instruction instructing the user to perform a predetermined exercise; performing a measurement session while the user performs the predetermined exercise, and storing a result from the measurement session, the result preferably comprising the user's heart rhythm and / or oxygen saturation and / or ability to adjust the user's heart rhythm to a normal -training level. 27. Werkwijze volgens conclusie 26, voorts omvattende: het meten van de algemene conditie van de gebruiker op basis van de meetsessie en/of voorgaande meetsessies; het weergeven van een indicatie van de algemene conditie en/of gezondheid van de gebruiker, bij voorkeur omvattende een grafische representatie van een persoon met een algemene conditie corresponderend met de algemene conditie van de gebruiker.The method of claim 26, further comprising: measuring the general condition of the user based on the measurement session and / or previous measurement sessions; displaying an indication of the general condition and / or health of the user, preferably comprising a graphical representation of a person with a general condition corresponding to the general condition of the user. 28. Werkwijze volgens conclusie 27, waarbij de grafische representatie beweegt en/of is gekleurd corresponderend met de algemene conditie van de gebruiker en/of het houden aan het oefenschema.The method of claim 27, wherein the graphical representation moves and / or is colored corresponding to the general condition of the user and / or adhering to the exercise schedule. 29. Lichaamsgedragen inrichting voor het meten van een signaal representatief voor een fysiologische parameter omvattende een bevestigingsband, een regeleenheid, een verwerkingseenheid, een actuator, en ten minste een sensor voor het meten van de signaalwaarde; waarbij de ten minste ene sensor dusdanig geplaatst is op de bevestigingsband van de lichaamsgedragen inrichting dat wanneer gedragen de ten minste ene sensor aanligt tegen het lichaam van een gebruiker; waarbij de actuator is ingericht voor het uitoefenen van een kracht op de ten minste ene sensor in een richting in hoofdzaak loodrecht op het lichaam van de gebruiker; waarbij de verwerkingseenheid is ingericht voor het bepalen van een amplitude-enveloppe van de gemeten signaalwaarde; waarbij de verwerkingseenheid daarin gedefinieerd een amplitude-enveloppe-regelband heeft met een enveloppe-bovenamplitudewaarde en enveloppe-onderamplitudewaarde, en waarbij de regeleenheid is ingericht voor het regelen van de door de actuator uitgeoefende kracht zodanig dat de gemeten signaalwaarde binnen de amplitude-enveloppe-regelband is.A body-based device for measuring a signal representative of a physiological parameter comprising a mounting tape, a control unit, a processing unit, an actuator, and at least one sensor for measuring the signal value; wherein the at least one sensor is positioned on the mounting strap of the body-supported device such that when worn, the at least one sensor abuts the body of a user; wherein the actuator is adapted to exert a force on the at least one sensor in a direction substantially perpendicular to the body of the user; wherein the processing unit is adapted to determine an amplitude envelope of the measured signal value; wherein the processor defined therein has an amplitude envelope control band with an envelope top amplitude value and envelope bottom amplitude value, and wherein the control unit is adapted to control the force exerted by the actuator such that the measured signal value within the amplitude envelope control band is. 30. Inrichting volgens conclusie 29, waarbij de regeleenheid is ingericht voor het verminderen van de kracht wanneer de amplitude van het gemeten signaal de enveloppe-bovenamplitudewaarde overschrijdt en voor het vergroten van de kracht wanneer de amplitude van het gemeten signaal onder de enveloppe-onderamplitudewaarde is.The apparatus of claim 29, wherein the control unit is adapted to reduce the force when the amplitude of the measured signal exceeds the envelope upper amplitude value and to increase the force when the amplitude of the measured signal is below the envelope lower amplitude value . 31. Inrichting volgens conclusie 29 of 30 waarin de ten minste ene sensor ten minste en lichtbron omvat met een lichtuitstraalvlak en ten minste een lichtontvanger met een lichtontvangvlak; waarbij de ten minste ene lichtbron en de ten minste ene lichtontvager dusdanig zijn geplaatst of de bevestigingsband van de inrichting dat wanneer gedragen de het ten minste ene lichtuitstraalvlak en het ten minste en elichtontvangvlak in hoofdzaak aanliggen tegen de palm air e zijde van de ols van een gebruiker; waarbij de actuator is in gericht voor het uitoefenen van een kracht op de ten minste ene lichtbron en/of de ten minste ene lichtontvanger in een richting in hoofdzaak loodrecht op de palm air e zijde van de gebruiker’s pols; waarbij de ten minste ene lichtbron is ingericht voor het uitzenden van licht in een golflengtebereik; waarbij de ten minste ene lichtontvanger is ingericht voor het produceren van een ontvangen-lichtsignaal corresponderend met een ontvangen intensiteit van het licht ontvangen aan het ten minste ene lichtontvangvlak; waarbij de verwerkingseenheid is ingericht voor het bepalen van een amplitude-enveloppe van het ontvangen-lichtsignaal; waarbij de verwerkingseenheid daaring gedefinieerd een amplitude-eveloppe-regelband heeft met een enveloppe-bovenamplitudewaarde en een eveloppe-onderamplitudewaarde, en waarbij de regeleenheid is ingericht voor het regelen van de door de actuator uitgeoefende kracht dusdanig dat het ontvangen-lichtsignaal binnen de amplitude-enveloppe-regelband is.An apparatus according to claim 29 or 30, wherein the at least one sensor comprises at least one light source with a light-emitting surface and at least one light receiver with a light-receiving surface; wherein the at least one light source and the at least one light receiver are positioned or the mounting band of the device such that when worn, the at least one light-emitting surface and the at least one light-receiving surface substantially abut the palm air side of the ols of an ols user; wherein the actuator is adapted to exert a force on the at least one light source and / or the at least one light receiver in a direction substantially perpendicular to the palm air side of the user's wrist; wherein the at least one light source is adapted to emit light in a wavelength range; wherein the at least one light receiver is adapted to produce a received light signal corresponding to a received intensity of the light received at the at least one light receiving surface; wherein the processing unit is adapted to determine an amplitude envelope of the received light signal; wherein the processing unit defined herein has an amplitude level control band with an envelope top amplitude value and an level bottom amplitude value, and wherein the control unit is adapted to control the force exerted by the actuator such that the received light signal within the amplitude envelope control band is. 32. Inrichting volgens conclusie 31, waarbij de regeleenheid voorts is in gericht voor het regelen van een door de ten minste ene lichtbron uitgezonden lichtintensiteit dusdanig dat de amplitude van het ontvangen-lichtsignaal binnen de amplitude -en velopp e -r e gelb an d is.An apparatus according to claim 31, wherein the control unit is further adapted to control a light intensity emitted by the at least one light source such that the amplitude of the received light signal is within the amplitude and velocity. 33. In richting volgens een der conclusies 29-32, voorts omvattende een draadloze communicatie-eenheid ingericht voor het communiceren met een communicatieinrichting, zoals een smartphone met beeldscherm.A device according to any of claims 29-32, further comprising a wireless communication unit adapted to communicate with a communication device, such as a smartphone with a display. 34. Inrichting volgens een der conclusies 29-33, waarbij de bevestigingsband is voorzien van geweven, gebreide en/of geborduurde elektrische verbindingsdraden die de ten minste ene sensor verbinden met de regeleenheid.Device as claimed in any of the claims 29-33, wherein the fixing tape is provided with woven, knitted and / or embroidered electrical connecting wires which connect the at least one sensor to the control unit. 35. Inrichting volgens conclusie 31 of een der conclusies 32-34 voor zover afhankelijke van conclusie 31, waarbij de ten minste ene lichtbron een optische fiber omvat voor het geleiden van licht naar de huid van de gebruiker en/of waarin de ten minste ene lichtontvanger een optische fiber omvat voor het geleiden van licht vanaf de huid van de gebruiker.An apparatus according to claim 31 or any of claims 32-34 as far as dependent on claim 31, wherein the at least one light source comprises an optical fiber for guiding light to the skin of the user and / or wherein the at least one light receiver an optical fiber for guiding light from the user's skin. 36. Inrichting volgens conclusie 35, waarbij de optische fiber in de bevestigingsband is geweven, gebreid en/of geborduurd.The device of claim 35, wherein the optical fiber is woven, knitted and / or embroidered in the fastening tape. 37. Inrichting volgens conclusie 35 of 36, waarbij ten minste een deel van de optische fiber dat is gepositioneerd is om mechanisch de huid van de gebruiker te raken i behandeld om licht te laten in- en/of uitkoppelen.An apparatus according to claim 35 or 36, wherein at least a portion of the optical fiber positioned to mechanically touch the user's skin is treated to allow light to be coupled in and / or uncoupled. 38. Inrichting volgens conclusie 31 of een der conclusies 32-37 voor zover afhankelijk van conclusie 31, omvattende een veelvoud van actuatoren en een veelvoud van lichtbronnen met een veelvoud van lichtuitzendvlakken en een veelvoud van lichtontvangers met een veelvoud van lichtontvangvakken waarbij elke actuator is ingericht voor het uitoefenen van een kracht op een lichtuitzendvlak en/of een lichtontvangvlak, waarbij de regeleenheid is ingericht voor het onafhankelijk actueren van elke actuator.An apparatus according to claim 31 or any of claims 32-37 as far as dependent on claim 31, comprising a plurality of actuators and a plurality of light sources with a plurality of light emitting surfaces and a plurality of light receivers with a plurality of light receiving compartments, each actuator being arranged for applying a force to a light emitting surface and / or a light receiving surface, the control unit being adapted to independently actuate each actuator. 39. Inrichting volgens conclusie 31 of een der conclusies 32-38 voor zover afhankelijk van conclusie 31, waarbij het lichtuitzendvlak van de ten minste ene lichtbron en/of het lichtontvangvlak van de lichtontvanger is bedekt met een transparante zachte polymeer bedekking en omgeven door een elastisch frame van lichtblokkerend polymeermateriaal.An apparatus according to claim 31 or any of claims 32-38 as far as dependent on claim 31, wherein the light emitting surface of the at least one light source and / or the light receiving surface of the light receiver is covered with a transparent soft polymer coating and surrounded by an elastic frame made of light-blocking polymeric material. 40. Inrichting volgens conclusie 39, waarbij de bedekking bolvormig is en is ingericht om naar binnen naar de palm air e zijde van de pols te worden gedrukt door het afstellen van de bevestigingsband en/of de actuator.The device of claim 39, wherein the cover is spherical and is adapted to be pushed inward toward the palm air side of the wrist by adjusting the mounting strap and / or the actuator. 41. Inrichting volgens een der conclusies 29-40, waarbij de verwerkingseenheid is in gericht voor het detecteren of de inrichting correct wordt gedragen aan de pols op basis van het gemeten signaal.An apparatus according to any one of claims 29-40, wherein the processing unit is adapted to detect whether the apparatus is correctly worn on the wrist based on the measured signal. 42. Inrichting volgens een der conclusies 29-41, voorts omvattende een versnellingsmeter ingericht voor het detecteren van de mate van beweging van de pols van de gebruiker.An apparatus according to any of claims 29-41, further comprising an accelerometer adapted to detect the amount of movement of the user's wrist. 43. Inrichting volgens een der conclusies 29-42, waarbij de verwerkingseenheid is ingericht voor het bepalen van de bloedsamenstelling van de gebruiker.An apparatus according to any one of claims 29-42, wherein the processing unit is adapted to determine the blood composition of the user. 44. Inrichting volgens een der conclusies 29-43, voorts omvattende een regeleenheid ingericht voor het bepalen van een gezondheidstoestand, zoals een fysiologische parameter, zoals een hartslag, een hartslagvariabiliteit, een hartslag-herstelvermogen, ademhalingssnelheid, C02-gehalte in bloedvaten en/of zuurstofsaturatie, van de door de ten minste ene sensor gemeten signaalwaarde.An apparatus according to any one of claims 29-43, further comprising a control unit adapted to determine a health condition, such as a physiological parameter, such as a heartbeat, a heartbeat variability, a heartbeat recovery capacity, respiratory rate, CO2 content in blood vessels and / or oxygen saturation, of the signal value measured by the at least one sensor.
NL2013091A 2014-06-30 2014-06-30 Body worn measurement device. NL2013091B1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
NL2013091A NL2013091B1 (en) 2014-06-30 2014-06-30 Body worn measurement device.
US15/322,924 US20170172476A1 (en) 2014-06-30 2015-06-26 Body worn measurement device
EP15736679.0A EP3160337B1 (en) 2014-06-30 2015-06-26 Body worn measurement device
PCT/NL2015/050468 WO2016003269A1 (en) 2014-06-30 2015-06-26 Body worn measurement device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL2013091A NL2013091B1 (en) 2014-06-30 2014-06-30 Body worn measurement device.

Publications (1)

Publication Number Publication Date
NL2013091B1 true NL2013091B1 (en) 2016-07-11

Family

ID=51302748

Family Applications (1)

Application Number Title Priority Date Filing Date
NL2013091A NL2013091B1 (en) 2014-06-30 2014-06-30 Body worn measurement device.

Country Status (1)

Country Link
NL (1) NL2013091B1 (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030036685A1 (en) * 2000-04-27 2003-02-20 Vitalsines International, Inc. Physiological signal monitoring system
US20070055163A1 (en) * 2005-08-22 2007-03-08 Asada Haruhiko H Wearable blood pressure sensor and method of calibration
US20090018453A1 (en) * 2007-06-12 2009-01-15 Triage Wireless, Inc. Vital sign monitor for measuring blood pressure using optical, electrical and pressure waveforms
US20110105918A1 (en) * 2009-10-29 2011-05-05 Cnsystems Medizintechnik Ag Apparatus and method for enhancing and analyzing signals from a continuous non-invasive blood pressure device
US20120229270A1 (en) * 2011-03-11 2012-09-13 Christopher Morley Wearable biofeedback system
JP2013063203A (en) * 2011-09-20 2013-04-11 Rohm Co Ltd Pulse wave sensor
US20130253332A1 (en) * 2012-03-20 2013-09-26 Nellcor Puritan Bennett Llc Tissue interface systems for application of optical signals into tissue of a patient

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030036685A1 (en) * 2000-04-27 2003-02-20 Vitalsines International, Inc. Physiological signal monitoring system
US20070055163A1 (en) * 2005-08-22 2007-03-08 Asada Haruhiko H Wearable blood pressure sensor and method of calibration
US20090018453A1 (en) * 2007-06-12 2009-01-15 Triage Wireless, Inc. Vital sign monitor for measuring blood pressure using optical, electrical and pressure waveforms
US20110105918A1 (en) * 2009-10-29 2011-05-05 Cnsystems Medizintechnik Ag Apparatus and method for enhancing and analyzing signals from a continuous non-invasive blood pressure device
US20120229270A1 (en) * 2011-03-11 2012-09-13 Christopher Morley Wearable biofeedback system
JP2013063203A (en) * 2011-09-20 2013-04-11 Rohm Co Ltd Pulse wave sensor
US20130253332A1 (en) * 2012-03-20 2013-09-26 Nellcor Puritan Bennett Llc Tissue interface systems for application of optical signals into tissue of a patient

Similar Documents

Publication Publication Date Title
EP3160337B1 (en) Body worn measurement device
JP6595479B2 (en) System and method for enhancing sleep wave removal activity based on cardiac or respiratory characteristics
US9532745B2 (en) Breathing guidance apparatus for delivery rooms
US20140221848A1 (en) Biological information detecting device, biological information detecting method, and biological information detection program
WO2016003268A2 (en) Method and device for measuring a health status and physiological parameters of an user at rest and under movement
AU2006217448A2 (en) Methods and systems for physiological and psycho-physiological monitoring and uses thereof
US20190357850A1 (en) Respiration rate detection device and breath detection device adopting motion denoising
KR20110041558A (en) Blood analysis
WO2016119654A1 (en) Physiological feedback system and light-emitting device
WO2016119659A1 (en) Ear-worn physiological detection device
US20170014041A1 (en) Simple heart rate monitor showing minutes below, in, and above a heart rate zone
NL2013091B1 (en) Body worn measurement device.
TWI558374B (en) Physiological feedback system
NL2013095B1 (en) Method and device for measuring a health status of a user.
WO2016119657A1 (en) Blood pressure management device, system, and method for use in regulating blood pressure
NL1041276B1 (en) Method and device for measuring a health status and physiological parameters of an user at rest and under movement
TWI653028B (en) Wearable physiological detection device
TWI650105B (en) Wearable physiological detection device
TWI559172B (en) Physiological feedback system
JP6238278B2 (en) Pulsation measurement device, pulsation measurement method, and program
TWI541681B (en) Physiological feedback system
TWI586324B (en) Blood pressure management device and method
TWI586323B (en) Blood pressure management device and method
TWI586322B (en) Blood pressure management device and method
TW201720371A (en) Breath detection device and operating method thereof

Legal Events

Date Code Title Description
MM Lapsed because of non-payment of the annual fee

Effective date: 20230701