NL191150C - N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat. - Google Patents

N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat.

Info

Publication number
NL191150C
NL191150C NL7905953A NL7905953A NL191150C NL 191150 C NL191150 C NL 191150C NL 7905953 A NL7905953 A NL 7905953A NL 7905953 A NL7905953 A NL 7905953A NL 191150 C NL191150 C NL 191150C
Authority
NL
Netherlands
Prior art keywords
preparation
leucyl
doxorubicin
acid addition
addition salts
Prior art date
Application number
NL7905953A
Other languages
English (en)
Dutch (nl)
Other versions
NL191150B (nl
NL7905953A (nl
Original Assignee
Ass A But Scienti Internationa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ass A But Scienti Internationa filed Critical Ass A But Scienti Internationa
Publication of NL7905953A publication Critical patent/NL7905953A/nl
Publication of NL191150B publication Critical patent/NL191150B/xx
Application granted granted Critical
Publication of NL191150C publication Critical patent/NL191150C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7905953A 1978-08-03 1979-08-02 N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat. NL191150C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE869485 1978-08-03
BE869485 1978-08-03

Publications (3)

Publication Number Publication Date
NL7905953A NL7905953A (nl) 1980-02-05
NL191150B NL191150B (nl) 1994-09-16
NL191150C true NL191150C (nl) 1995-02-16

Family

ID=3861689

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7905953A NL191150C (nl) 1978-08-03 1979-08-02 N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat.

Country Status (6)

Country Link
US (1) US4296105A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5522697A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1115694A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2432525A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2027024B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL191150C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
ES2297832T3 (es) * 1994-08-19 2008-05-01 La Region Wallonne Conjugados que comprenden un agente antitumoral y su utilizacion.
BE1008581A3 (fr) * 1994-08-19 1996-06-04 Wallone Region Prodrogues, composition pharmaceutique les comprenant et leur utilisation.
JP2543434Y2 (ja) * 1996-04-15 1997-08-06 マツダ株式会社 エンジンの排気管構造
US5998362A (en) * 1996-09-12 1999-12-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
KR100580137B1 (ko) * 1997-12-02 2006-05-16 머크 앤드 캄파니 인코포레이티드 전립선 암 치료에 유용한 접합체 및 이를 포함하는 약제학적 조성물
ZA9810974B (en) * 1997-12-02 1999-06-03 Merck & Co Inc Conjugates useful in the treatment of prostate cancer
US20040081659A1 (en) * 1997-12-02 2004-04-29 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6174858B1 (en) 1998-11-17 2001-01-16 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
CA2388700A1 (en) 1999-10-19 2001-04-26 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6355611B1 (en) 1999-10-27 2002-03-12 Merck & Co., Inc. Salt form of a conjugate useful in the treatment of prostate cancer
HK1049443A1 (zh) * 1999-11-12 2003-05-16 Angiotech Pharmaceuticals, Inc. 用放射活性疗法和细胞循环抑制剂联合治疗疾病的组合物和方法
AU2001266853B2 (en) 2000-06-14 2005-02-17 Medarex, Inc. Prodrug compounds with an oligopeptide having an isoleucine residue
US7402556B2 (en) * 2000-08-24 2008-07-22 Medarex, Inc. Prodrugs activated by plasmin and their use in cancer chemotherapy
US20030232760A1 (en) * 2001-09-21 2003-12-18 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
CN100341589C (zh) 2002-05-24 2007-10-10 血管技术国际股份公司 用于涂覆医用植入物的组合物和方法
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
US20040146546A1 (en) 2002-09-26 2004-07-29 Angiotech Pharmaceuticals, Inc. Perivascular wraps
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
WO2005051451A2 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Electrical devices and anti-scarring agents
EP1718145A4 (en) 2004-02-02 2012-03-07 Biosight Ltd CONJUGATES FOR CANCER THERAPY AND DIAGNOSIS
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
US9789209B2 (en) 2013-03-14 2017-10-17 The Regents Of The University Of California, Berke Activatable membrane-interacting peptides and methods of use
IL259569B2 (en) 2015-12-03 2024-03-01 Biosight Ltd Salts of cytarabine-amino acids conjugates
CN108289905A (zh) 2015-12-03 2018-07-17 拜欧赛特有限公司 用于癌症疗法的阿糖胞苷缀合物
US12071450B2 (en) 2015-12-03 2024-08-27 Biosight Ltd. Salts of conjugates for cancer therapy
US12064445B2 (en) 2015-12-03 2024-08-20 Biosight Ltd. Cytarabine conjugates for cancer therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1578734A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1967-11-28 1969-08-22
FR7164M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1968-02-22 1969-08-04
FI51808C (fi) * 1968-07-15 1977-04-12 Rhone Poulenc Sa Menetelmä uusien kasvainten naftaseenijohdannaisten valmistamiseksi.
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4012448A (en) * 1976-01-15 1977-03-15 Stanford Research Institute Synthesis of adriamycin and 7,9-epiadriamycin
FR2430425A1 (fr) * 1978-07-07 1980-02-01 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
NL191150B (nl) 1994-09-16
GB2027024B (en) 1983-04-27
FR2432525B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-12-02
CA1115694A (en) 1982-01-05
NL7905953A (nl) 1980-02-05
JPS6259715B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-12-12
JPS5522697A (en) 1980-02-18
FR2432525A1 (fr) 1980-02-29
GB2027024A (en) 1980-02-13
US4296105A (en) 1981-10-20

Similar Documents

Publication Publication Date Title
NL191150C (nl) N-(L-leucyl) doxorubicine en zuur-additiezouten daarvan, werkwijze ter bereiding en farmaceutische preparaat.
BE847742A (fr) Nouvelles imidazolidines, procede de preparation et compositions pharmaceutiques
FI792009A7 (fi) 3-aminopropoksiaryylijohdannaisia, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset.
IT1194900B (it) N-(fenossialchile)immidazoli,relative composizioni farmaceutiche e procedimento per la loro fabbricazione
FI803849A7 (fi) Uudet asyylipeptidit, niistä valmistetut farmaseuttiset valmisteet, menetelmä niiden valmistamiseksi ja niiden käyttö.
FI791656A7 (fi) Vatsahapon eritystä vastustavia tiadiatsolijohdannaisia, niiden valmistusmenetelmiä ja niitä sisältävifarmaseuttisia valmisteita.
FI802918A7 (fi) Aminohappojohdannaisia ja menetelmä niiden valmistamiseksi.
FI813862A7 (fi) Uusia 8-aryylialkyyli-3- fenyyli-3- nortropanoleja, niiden happoadditiosuoloja, näitä sisältäviä lääkeainelääkeaineita ja menetelmiä niiden valmistamiseksi.
ATE921T1 (de) Saeureadditionssalze von 2-beta, 16-beta-bis-piperidino-an drostan-16-beta-monoquaternaeren ammoniumderivaten und diese enthaltende pharmazeutische zusammensetzungen.
IT1125469B (it) Composto 2-metil-diidropirindinico,procedimenti per la sua preparazione e composizione farmaceutica che lo comprende
FI801168A7 (fi) Penem-3- karboksyylihapon johdannaiset, niiden valmistus ja käyttö.
NL190662B (nl) Alfa-halogeenmethyl-alfa-aminozuurderivaten en farmaceutisch preparaat dat dit bevat.
DE2961804D1 (en) N-(3-benzoylpropyl)-spiro-(dihydrobenzofuranpiperidines and -pyrrolidines), derivatives thereof, methods for their preparation and their use for medicines
NL188645B (nl) 1-azaxanthon-3-carbonzuurverbindingen en farmaceutische preparaten die deze verbindingen bevatten.
NL7901241A (nl) Nieuwe gesubstitueerde 2-fenylimino-imidazolidinen, de zuuradditiezouten daarvan, farmaceutische preparaten die deze bevatten, alsmede werkwijze voor de bereiding daarvan.
NL174345B (nl) Zuur alkalicitraat, werkwijze ter bereiding daarvan en therapeutisch preparaat.
NL7900264A (nl) 4-pyridon-3-carbonzuurderivaten alsmede de bereiding ervan.
FI803202A7 (fi) Fosfonohydroksietikkahappo, sen valmistusmenetelmä sekä käyttö lääkeaineena.
NL7903769A (nl) Di-o-n-alkylglycerolderivaten en farmaceutische preparaten daarvan.
NL187397C (nl) Farmaceutische preparaten, 20,21-dinoreburnamenineverbindingen daarvoor en werkwijze voor hun bereiding.
FI791424A7 (fi) Substituoidut 8-hydroksi-1-fenyyli-2,3,4,5-tetrahydro-1H-3- bentsatsepiinit, menetelmä niiden valmistamiseksi jniitä sisältävät farmaseuttiset seokset.
IT7926854A0 (it) Derivato di creatinolo o-fosfato ad azione terapeutica, procedimento per la sua preparazione e relativ-e composizioni farmaceutiche.
BE865816A (fr) Derives d'acide benzoique, leur procede de preparation et leur application therapeutique.
FI803908A7 (fi) Uusia pyrrolobentsotriatsepiineja, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset.
FI793848A7 (fi) Bensoksadiatsoleja ja bensotiadiatsoleja, niiden valmistus ja farmaseuttisia yhdisteitä, jotka sisältävät näitä

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V1 Lapsed because of non-payment of the annual fee

Effective date: 19960301