NL188157C - Werkwijze voor de bereiding van o-gealkyleerde hydroxylaminen, werkwijze ter bereiding van een geneesmiddel daaruit en gevormd geneesmiddel. - Google Patents
Werkwijze voor de bereiding van o-gealkyleerde hydroxylaminen, werkwijze ter bereiding van een geneesmiddel daaruit en gevormd geneesmiddel.Info
- Publication number
- NL188157C NL188157C NLAANVRAGE7712291,A NL7712291A NL188157C NL 188157 C NL188157 C NL 188157C NL 7712291 A NL7712291 A NL 7712291A NL 188157 C NL188157 C NL 188157C
- Authority
- NL
- Netherlands
- Prior art keywords
- medicinal product
- hydroxylamins
- alkylated
- preparing
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762651083 DE2651083A1 (de) | 1976-11-09 | 1976-11-09 | Neue o-alkylierte hydroxylamine, verfahren zu ihrer herstellung und ihre verwendung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL7712291A NL7712291A (nl) | 1978-05-11 |
| NL188157B NL188157B (nl) | 1991-11-18 |
| NL188157C true NL188157C (nl) | 1992-04-16 |
Family
ID=5992722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE7712291,A NL188157C (nl) | 1976-11-09 | 1977-11-08 | Werkwijze voor de bereiding van o-gealkyleerde hydroxylaminen, werkwijze ter bereiding van een geneesmiddel daaruit en gevormd geneesmiddel. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4404384A (fi) |
| JP (1) | JPS5817454B2 (fi) |
| AT (1) | AT363452B (fi) |
| AU (1) | AU520996B2 (fi) |
| BE (1) | BE860614A (fi) |
| CA (1) | CA1081242A (fi) |
| CH (1) | CH641757A5 (fi) |
| DE (1) | DE2651083A1 (fi) |
| DK (1) | DK496977A (fi) |
| ES (1) | ES463803A1 (fi) |
| FI (1) | FI773353A (fi) |
| FR (1) | FR2370028A1 (fi) |
| GB (1) | GB1540028A (fi) |
| HU (1) | HU176533B (fi) |
| IL (1) | IL53337A0 (fi) |
| NL (1) | NL188157C (fi) |
| SE (1) | SE441265B (fi) |
| ZA (1) | ZA776670B (fi) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2651083A1 (de) * | 1976-11-09 | 1978-05-18 | Hoechst Ag | Neue o-alkylierte hydroxylamine, verfahren zu ihrer herstellung und ihre verwendung |
| EP0369944A1 (de) * | 1988-11-18 | 1990-05-23 | Ciba-Geigy Ag | Substituierte Oxadiaminobutane |
| US4965390A (en) * | 1990-02-02 | 1990-10-23 | Ciba-Geigy Corporation | Hydroxamic acid esters |
| US5075504A (en) * | 1990-02-02 | 1991-12-24 | Ciba-Geigy Corporation | Process for the preparation of O-substituted hydroxylamines |
| IL97759A0 (en) * | 1990-04-11 | 1992-06-21 | Ciba Geigy Ag | Hydroxylamine compounds |
| HU207290B (en) * | 1990-06-13 | 1993-03-29 | Sandoz Ag | Process for producing hydroxamic acid derivatives and pharmaceutical compositions containing them |
| EP0495750A3 (en) * | 1991-01-14 | 1992-09-16 | Ciba-Geigy Ag | Heterocyclic hydroxylamine |
| DE4244390A1 (de) * | 1992-12-29 | 1994-06-30 | Basf Ag | Verfahren zur Herstellung von Oximino-Derivaten und neue Oximino-Derivate |
| HU218480B (hu) * | 1995-06-15 | 2000-09-28 | BIOREX Kutató és Fejlesztő Rt. | Hidroxilaminszármazékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények |
| HU222994B1 (hu) | 1995-11-02 | 2004-01-28 | BIOREX Kutató és Fejlesztő Rt. | Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására |
| WO2003057664A1 (en) | 2002-01-11 | 2003-07-17 | Biorex Kutató És Fejlesztö Rt. | Carboxamidine derivatives and their use in the treatment of vascular diseases |
| HUP0303584A3 (en) | 2003-10-30 | 2009-12-28 | Cytrx Corp | Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases |
| DE102005044108A1 (de) | 2005-09-15 | 2007-03-29 | Bayer Cropscience Ag | Dioxazin- und Oxdiazin-substituierte Arylamide |
| TW200831479A (en) * | 2006-09-26 | 2008-08-01 | Cytrx Corp | Pharmaceutical compositions and methods for treating diseases |
| KR20140121469A (ko) * | 2012-02-03 | 2014-10-15 | 노파르티스 아게 | N-(4-시클로헥실-3-트리플루오로메틸-벤질옥시)-아세트이미드산 에틸 에스테르의 제조 방법 |
| MX2023005954A (es) | 2020-11-19 | 2023-09-04 | Zevra Denmark As | Procesos para preparar citrato de arimoclomol e intermediarios del mismo. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1149364B (de) * | 1960-07-05 | 1963-05-30 | Bayer Ag | Verfahren zur Herstellung von O-(Alkylamino)-hydroxylaminen |
| GB1017601A (en) * | 1961-02-22 | 1966-01-19 | Lepetit Spa | O-(ª‰-hydroxyethyl)-hydroxylamine and derivatives thereof |
| US3262978A (en) * | 1963-06-19 | 1966-07-26 | Colgate Palmolive Co | O-arylamino-and-aralkyl-amino-alkylhydroxyl-amines |
| US3342678A (en) * | 1964-02-10 | 1967-09-19 | Carter Wallace | Lowering blood cholesterol levels in warm-blooded animals with phenoxyethoxy or phenoxy-propoxy amine derivatives |
| HU162578B (fi) * | 1971-02-15 | 1973-03-28 | ||
| CA1012540A (en) * | 1972-06-17 | 1977-06-21 | Sumitomo Chemical Company | 2-propanol derivatives and preparation thereof |
| DE2651084A1 (de) * | 1976-11-09 | 1978-12-14 | Hoechst Ag | Basisch substituirte o-(2-hydroxypropyl) -aldoxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE2651083A1 (de) * | 1976-11-09 | 1978-05-18 | Hoechst Ag | Neue o-alkylierte hydroxylamine, verfahren zu ihrer herstellung und ihre verwendung |
| DE2658762A1 (de) * | 1976-12-24 | 1978-06-29 | Hoechst Ag | Neue o-alkylierte oxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE2820013A1 (de) * | 1978-05-08 | 1979-11-22 | Hoechst Ag | Verfahren zur herstellung von o-alkylierten hydroxylaminen |
-
1976
- 1976-11-09 DE DE19762651083 patent/DE2651083A1/de active Granted
-
1977
- 1977-11-03 ES ES463803A patent/ES463803A1/es not_active Expired
- 1977-11-07 AT AT0794477A patent/AT363452B/de not_active IP Right Cessation
- 1977-11-08 FI FI773353A patent/FI773353A/fi not_active Application Discontinuation
- 1977-11-08 BE BE182455A patent/BE860614A/xx not_active IP Right Cessation
- 1977-11-08 NL NLAANVRAGE7712291,A patent/NL188157C/xx not_active IP Right Cessation
- 1977-11-08 FR FR7733559A patent/FR2370028A1/fr active Granted
- 1977-11-08 AU AU30433/77A patent/AU520996B2/en not_active Expired
- 1977-11-08 IL IL53337A patent/IL53337A0/xx not_active IP Right Cessation
- 1977-11-08 DK DK496977A patent/DK496977A/da not_active Application Discontinuation
- 1977-11-08 CA CA290,477A patent/CA1081242A/en not_active Expired
- 1977-11-08 ZA ZA00776670A patent/ZA776670B/xx unknown
- 1977-11-08 GB GB46473/77A patent/GB1540028A/en not_active Expired
- 1977-11-08 HU HU77HO2024A patent/HU176533B/hu not_active IP Right Cessation
- 1977-11-08 JP JP52133163A patent/JPS5817454B2/ja not_active Expired
- 1977-11-08 SE SE7712630A patent/SE441265B/xx not_active IP Right Cessation
-
1978
- 1978-01-01 CH CH1349277A patent/CH641757A5/de not_active IP Right Cessation
-
1981
- 1981-05-28 US US06/267,722 patent/US4404384A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES463803A1 (es) | 1978-06-16 |
| JPS5368711A (en) | 1978-06-19 |
| FI773353A (fi) | 1978-05-10 |
| GB1540028A (en) | 1979-02-07 |
| NL7712291A (nl) | 1978-05-11 |
| HU176533B (en) | 1981-03-28 |
| CH641757A5 (en) | 1984-03-15 |
| FR2370028A1 (fr) | 1978-06-02 |
| DE2651083A1 (de) | 1978-05-18 |
| SE7712630L (sv) | 1978-05-10 |
| BE860614A (fr) | 1978-05-08 |
| AU3043377A (en) | 1979-05-17 |
| JPS5817454B2 (ja) | 1983-04-07 |
| SE441265B (sv) | 1985-09-23 |
| US4404384A (en) | 1983-09-13 |
| ATA794477A (de) | 1981-01-15 |
| DE2651083C2 (fi) | 1988-08-04 |
| IL53337A0 (en) | 1978-01-31 |
| ZA776670B (en) | 1978-08-30 |
| AU520996B2 (en) | 1982-03-11 |
| NL188157B (nl) | 1991-11-18 |
| CA1081242A (en) | 1980-07-08 |
| AT363452B (de) | 1981-08-10 |
| DK496977A (da) | 1978-05-10 |
| FR2370028B1 (fi) | 1980-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| V1 | Lapsed because of non-payment of the annual fee |
Effective date: 19960601 |