NL177913C - Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen. - Google Patents
Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen.Info
- Publication number
- NL177913C NL177913C NLAANVRAGE7510778,A NL7510778A NL177913C NL 177913 C NL177913 C NL 177913C NL 7510778 A NL7510778 A NL 7510778A NL 177913 C NL177913 C NL 177913C
- Authority
- NL
- Netherlands
- Prior art keywords
- tetrene
- nona
- dimethyl
- phenyl
- compounds
- Prior art date
Links
- IBFFCTHLESNHST-UHFFFAOYSA-N C1(=CC=CC=C1)CC=C(C=CC=C(C=C)C)C Chemical class C1(=CC=CC=C1)CC=C(C=CC=C(C=C)C)C IBFFCTHLESNHST-UHFFFAOYSA-N 0.000 title 1
- 230000010261 cell growth Effects 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5456—Arylalkanephosphonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/23—Preparation of halogenated hydrocarbons by dehalogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
- C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
- C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
- C07C205/20—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings
- C07C205/21—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C205/22—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring having one nitro groups bound to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
- C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
- C07C37/045—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1303274A CH605562A5 (hu) | 1974-09-26 | 1974-09-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL7510778A NL7510778A (nl) | 1976-03-30 |
| NL177913C true NL177913C (nl) | 1985-12-16 |
Family
ID=4388688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE7510778,A NL177913C (nl) | 1974-09-26 | 1975-09-12 | Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen. |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5951531B2 (hu) |
| AR (1) | AR212858A1 (hu) |
| AT (1) | AT346311B (hu) |
| BE (1) | BE833784A (hu) |
| BR (1) | BR7506154A (hu) |
| CA (1) | CA1050042A (hu) |
| CH (1) | CH605562A5 (hu) |
| CU (1) | CU34345A (hu) |
| DD (1) | DD122072A5 (hu) |
| DE (1) | DE2542612A1 (hu) |
| FR (1) | FR2285864B1 (hu) |
| GB (1) | GB1514975A (hu) |
| HU (1) | HU172958B (hu) |
| IE (1) | IE41801B1 (hu) |
| IL (1) | IL47929A (hu) |
| LU (1) | LU73452A1 (hu) |
| NL (1) | NL177913C (hu) |
| NZ (1) | NZ178425A (hu) |
| PH (1) | PH12883A (hu) |
| SU (1) | SU623515A3 (hu) |
| YU (1) | YU40124B (hu) |
| ZA (1) | ZA755208B (hu) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4338253A (en) | 1975-11-14 | 1982-07-06 | Hoffmann-La Roche Inc. | Fluorinated aromatic polyenes |
| US4335248A (en) | 1975-11-14 | 1982-06-15 | Hoffmann-La Roche Inc. | Fluorinated polyenes |
| US4375563A (en) | 1975-11-14 | 1983-03-01 | Hoffmann-La Roche Inc. | Fluorinated aromatic polyenes |
| US4201727A (en) | 1976-11-14 | 1980-05-06 | Hoffmann-La Roche Inc. | Fluorinated aromatic polyenes |
| US4321209A (en) | 1975-11-14 | 1982-03-23 | Hoffmann-La Roche Inc. | Fluorinated aromatic polyenes |
| US4299995A (en) | 1979-05-10 | 1981-11-10 | Hoffmann-La Roche Inc. | Fluorinated polyenes |
| US4266073A (en) * | 1975-11-14 | 1981-05-05 | Hoffmann-La Roche Inc. | Fluorinated aromatic polyenes |
| US4395575A (en) | 1975-11-14 | 1983-07-26 | Hoffmann-La Roche, Inc. | 5(Halophenyl)-2-fluoro-pentadienals |
| CA1111441A (en) * | 1976-12-20 | 1981-10-27 | Werner Bollag | Polyene compounds |
| US4200647A (en) * | 1977-12-21 | 1980-04-29 | Hoffmann-La Roche Inc. | Vitamin A compositions to treat rheumatic disease |
| US4642318A (en) * | 1982-11-17 | 1987-02-10 | Klaus Wolff | Method for decreasing radiation load in PUVA therapy |
| ZA854828B (en) * | 1984-07-27 | 1986-03-26 | Hoffmann La Roche | Phenyl nonatetraenoic acid derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1109671B (de) * | 1958-10-17 | 1961-06-29 | Basf Ag | Verfahren zur Herstellung von ª‡,ª‰-ungesaettigten Carbonsaeureestern oder der freien Saeuren |
-
1974
- 1974-09-26 CH CH1303274A patent/CH605562A5/xx not_active IP Right Cessation
-
1975
- 1975-08-13 ZA ZA00755208A patent/ZA755208B/xx unknown
- 1975-08-15 IL IL47929A patent/IL47929A/xx unknown
- 1975-08-19 NZ NZ178425A patent/NZ178425A/xx unknown
- 1975-08-26 CA CA234,206A patent/CA1050042A/en not_active Expired
- 1975-09-10 YU YU2287/75A patent/YU40124B/xx unknown
- 1975-09-12 NL NLAANVRAGE7510778,A patent/NL177913C/xx not_active IP Right Cessation
- 1975-09-12 AR AR260364A patent/AR212858A1/es active
- 1975-09-16 PH PH17579A patent/PH12883A/en unknown
- 1975-09-18 CU CU7534345A patent/CU34345A/es unknown
- 1975-09-23 JP JP50114373A patent/JPS5951531B2/ja not_active Expired
- 1975-09-24 BR BR7506154*A patent/BR7506154A/pt unknown
- 1975-09-24 HU HU75HO00001839A patent/HU172958B/hu unknown
- 1975-09-24 FR FR7529226A patent/FR2285864B1/fr not_active Expired
- 1975-09-24 DE DE19752542612 patent/DE2542612A1/de active Granted
- 1975-09-24 LU LU73452A patent/LU73452A1/xx unknown
- 1975-09-25 BE BE160342A patent/BE833784A/xx not_active IP Right Cessation
- 1975-09-25 SU SU752178997A patent/SU623515A3/ru active
- 1975-09-25 AT AT734775A patent/AT346311B/de not_active IP Right Cessation
- 1975-09-25 DD DD188555A patent/DD122072A5/xx unknown
- 1975-09-25 IE IE2098/75A patent/IE41801B1/en unknown
- 1975-09-26 GB GB39545/75A patent/GB1514975A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| YU228775A (en) | 1983-01-21 |
| PH12883A (en) | 1979-09-28 |
| NZ178425A (en) | 1978-03-06 |
| IL47929A (en) | 1978-07-31 |
| CA1050042A (en) | 1979-03-06 |
| DE2542612A1 (de) | 1976-04-22 |
| AT346311B (de) | 1978-11-10 |
| LU73452A1 (hu) | 1977-05-16 |
| DD122072A5 (hu) | 1976-09-12 |
| FR2285864A1 (fr) | 1976-04-23 |
| NL7510778A (nl) | 1976-03-30 |
| AR212858A1 (es) | 1978-10-31 |
| JPS5951531B2 (ja) | 1984-12-14 |
| IL47929A0 (en) | 1975-11-25 |
| GB1514975A (en) | 1978-06-21 |
| JPS51125233A (en) | 1976-11-01 |
| IE41801L (en) | 1976-03-26 |
| HU172958B (hu) | 1979-01-28 |
| YU40124B (en) | 1985-08-31 |
| BR7506154A (pt) | 1976-08-03 |
| DE2542612C2 (hu) | 1987-09-10 |
| CH605562A5 (hu) | 1978-09-29 |
| ZA755208B (en) | 1976-07-28 |
| CU34345A (es) | 1979-09-08 |
| FR2285864B1 (fr) | 1980-03-28 |
| AU8418775A (en) | 1977-02-24 |
| SU623515A3 (ru) | 1978-09-05 |
| ATA734775A (de) | 1978-03-15 |
| IE41801B1 (en) | 1980-03-26 |
| BE833784A (fr) | 1976-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| SNR | Assignments of patents or rights arising from examined patent applications |
Owner name: F. HOFFMANN-LA ROCHE AG |
|
| V1 | Lapsed because of non-payment of the annual fee |