NL172446C - Werkwijze voor de bereiding van 4-aryl-1-(4.4-diarylbutyl)4-hydroxypiperidinen en werkwijze voor de bereiding van farmaceutische preparaten. - Google Patents

Werkwijze voor de bereiding van 4-aryl-1-(4.4-diarylbutyl)4-hydroxypiperidinen en werkwijze voor de bereiding van farmaceutische preparaten.

Info

Publication number
NL172446C
NL172446C NLAANVRAGE7012199,A NL7012199A NL172446C NL 172446 C NL172446 C NL 172446C NL 7012199 A NL7012199 A NL 7012199A NL 172446 C NL172446 C NL 172446C
Authority
NL
Netherlands
Prior art keywords
preparation
diarylbutyl
hydroxypiperidines
aryl
pharmaceutical preparations
Prior art date
Application number
NLAANVRAGE7012199,A
Other languages
English (en)
Dutch (nl)
Other versions
NL7012199A (da
NL172446B (nl
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NL7012199A publication Critical patent/NL7012199A/xx
Publication of NL172446B publication Critical patent/NL172446B/xx
Application granted granted Critical
Publication of NL172446C publication Critical patent/NL172446C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/35—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C07C17/354—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction by hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NLAANVRAGE7012199,A 1969-09-03 1970-08-18 Werkwijze voor de bereiding van 4-aryl-1-(4.4-diarylbutyl)4-hydroxypiperidinen en werkwijze voor de bereiding van farmaceutische preparaten. NL172446C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85501669A 1969-09-03 1969-09-03

Publications (3)

Publication Number Publication Date
NL7012199A NL7012199A (da) 1971-03-05
NL172446B NL172446B (nl) 1983-04-05
NL172446C true NL172446C (nl) 1983-09-01

Family

ID=25320131

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7012199,A NL172446C (nl) 1969-09-03 1970-08-18 Werkwijze voor de bereiding van 4-aryl-1-(4.4-diarylbutyl)4-hydroxypiperidinen en werkwijze voor de bereiding van farmaceutische preparaten.

Country Status (22)

Country Link
US (1) US3575990A (da)
JP (1) JPS4932543B1 (da)
AT (1) AT299201B (da)
BE (1) BE755589A (da)
BR (1) BR6915392D0 (da)
CH (1) CH520671A (da)
CS (1) CS159779B2 (da)
DE (1) DE2040231C3 (da)
DK (1) DK127424B (da)
ES (1) ES383006A1 (da)
FI (1) FI51176C (da)
FR (1) FR2068536B1 (da)
GB (1) GB1294733A (da)
IL (1) IL35211A (da)
IT (1) IT1040516B (da)
NL (1) NL172446C (da)
NO (1) NO131173C (da)
PL (1) PL71070B1 (da)
RO (1) RO57021A (da)
SE (1) SE354066B (da)
YU (1) YU34354B (da)
ZA (1) ZA706024B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039676A (en) * 1975-06-23 1977-08-02 Ciba-Geigy Corporation 2-piperidinoalkyl-1,4-benzodioxans
US4129655A (en) * 1976-04-26 1978-12-12 Ciba-Geigy Corporation Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans
US4383999A (en) * 1981-05-26 1983-05-17 Smithkline Beckman Corporation Inhibition of GABA uptake by N-substituted azaheterocyclic carboxylic acids and their esters
US4514414A (en) * 1982-10-25 1985-04-30 Smithkline Beckman Corporation N-Substituted pyrrolidineacetic acids and their esters
IL90858A (en) * 1988-07-07 1994-08-26 Rhone Poulenc Sante History (Aza) Naftalensultam, their preparation and preparations containing them
DE102004036349A1 (de) * 2004-07-27 2006-03-23 Grünenthal GmbH Substituierte 3-Phenylpiperidin-Derivate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB931788A (en) * 1960-01-14 1963-07-17 Sandoz Ltd Improvements in or relating to benzhydryl esters

Also Published As

Publication number Publication date
DE2040231A1 (de) 1971-03-18
FR2068536B1 (da) 1973-07-13
JPS4932543B1 (da) 1974-08-31
GB1294733A (en) 1972-11-01
CS159779B2 (da) 1975-01-31
FR2068536A1 (da) 1971-08-27
IL35211A0 (en) 1970-11-30
NO131173B (da) 1975-01-06
NL7012199A (da) 1971-03-05
US3575990A (en) 1971-04-20
CH520671A (fr) 1972-03-31
BR6915392D0 (pt) 1973-01-16
YU218870A (en) 1978-12-31
PL71070B1 (da) 1974-04-30
AT299201B (de) 1972-06-12
ES383006A1 (es) 1973-07-01
NL172446B (nl) 1983-04-05
DE2040231C3 (de) 1979-04-12
DE2040231B2 (de) 1978-08-10
DK127424B (da) 1973-11-05
YU34354B (en) 1979-07-10
NO131173C (da) 1975-04-16
FI51176C (fi) 1976-11-10
IT1040516B (it) 1979-12-20
RO57021A (da) 1974-12-11
FI51176B (da) 1976-08-02
BE755589A (fr) 1971-03-02
SE354066B (da) 1973-02-26
IL35211A (en) 1973-11-28
ZA706024B (en) 1972-04-26

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Legal Events

Date Code Title Description
V4 Discontinued because of reaching the maximum lifetime of a patent