NL170627C - Werkwijze ter bereiding van een geneesmiddel met anti-epileptische en anti-convulsieve werking. - Google Patents
Werkwijze ter bereiding van een geneesmiddel met anti-epileptische en anti-convulsieve werking.Info
- Publication number
- NL170627C NL170627C NLAANVRAGE7607533,A NL7607533A NL170627C NL 170627 C NL170627 C NL 170627C NL 7607533 A NL7607533 A NL 7607533A NL 170627 C NL170627 C NL 170627C
- Authority
- NL
- Netherlands
- Prior art keywords
- epileptic
- preparing
- medicinal product
- convulsive action
- convulsive
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/10—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
- C07C251/16—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7524065A FR2319338A1 (fr) | 1975-08-01 | 1975-08-01 | Nouveaux derives de a- phenyl benzylideniques des acides amines, leur preparation et les medicaments qui en contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL7607533A NL7607533A (nl) | 1977-02-03 |
| NL170627C true NL170627C (nl) | 1982-12-01 |
Family
ID=9158650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE7607533,A NL170627C (nl) | 1975-08-01 | 1976-07-08 | Werkwijze ter bereiding van een geneesmiddel met anti-epileptische en anti-convulsieve werking. |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US4094992A (no) |
| JP (1) | JPS5219644A (no) |
| AR (1) | AR211548A1 (no) |
| AT (1) | AT346312B (no) |
| AU (1) | AU496994B2 (no) |
| BE (1) | BE844737A (no) |
| CA (1) | CA1072112A (no) |
| CH (1) | CH616148A5 (no) |
| DE (1) | DE2634288A1 (no) |
| DK (1) | DK346276A (no) |
| ES (1) | ES450300A1 (no) |
| FR (1) | FR2319338A1 (no) |
| GB (1) | GB1506808A (no) |
| GR (1) | GR60854B (no) |
| IE (1) | IE43143B1 (no) |
| IL (1) | IL50019A (no) |
| LU (1) | LU75514A1 (no) |
| MX (1) | MX4018E (no) |
| NL (1) | NL170627C (no) |
| NO (1) | NO142172C (no) |
| NZ (1) | NZ181444A (no) |
| PT (1) | PT65426B (no) |
| SE (1) | SE429651B (no) |
| ZA (1) | ZA764096B (no) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2516509B1 (fr) * | 1981-11-18 | 1985-07-26 | Synthelabo | Derives benzylideniques, leur preparation et leur application en therapeutique |
| FR2484410A2 (fr) * | 1979-02-12 | 1981-12-18 | Synthelabo | Derives benzylideniques et leur application en therapeutique |
| DE3124091C2 (de) | 1981-06-19 | 1983-06-01 | Degussa Ag, 6000 Frankfurt | N-(3-Cyanopropanoyl)-aminocarbonsäureester und deren Verwendung |
| US4478958A (en) * | 1981-07-10 | 1984-10-23 | Kopper Company, Inc. | Method for preparing phenolic foams using anhydrous aryl sulfonic acid catalysts |
| FR2535319B2 (fr) * | 1981-11-18 | 1985-10-31 | Synthelabo | Derives methyles benzylideniques, leur preparation et leur application en therapeutique |
| FR2535318B2 (fr) * | 1981-11-18 | 1985-09-06 | Synthelabo | Derives benzylideniques, leur preparation et leur application en therapeutique |
| FR2536070A1 (fr) * | 1982-11-15 | 1984-05-18 | Synthelabo | Diphenyl-azomethines hydroxylees, leur preparation et leur application en therapeutique |
| FR2536747A1 (fr) * | 1982-11-29 | 1984-06-01 | Synthelabo | Derives benzylideniques soufres, leur preparation et leur application en therapeutique |
| FR2536746A1 (fr) * | 1982-11-29 | 1984-06-01 | Synthelabo | Derives benzylideniques alkyles, leur preparation et leur application en therapeutique |
| FR2544309B1 (fr) * | 1983-04-14 | 1986-01-10 | Synthelabo | Diphenylazomethines hydroxylees, leur preparation et leur application en therapeutique |
| FR2544308B1 (fr) * | 1983-04-14 | 1985-06-14 | Synthelabo | Ethines substituees, leur preparation et leur application en therapeutique |
| FR2545822B1 (fr) * | 1983-05-11 | 1985-07-05 | Synthelabo | Diphenylazomethines portant une chaine esterifiee, leur preparation et leur application en therapeutique |
| FR2570696B1 (fr) * | 1984-09-27 | 1986-11-21 | Synthelabo | Derives de diphenylazomethines a chaine insaturee, leur preparation et leur application en therapeutique |
| FR2577923B1 (fr) * | 1985-02-26 | 1988-09-09 | Synthelabo | Diphenylazomethines carboxylees, leur preparation et leur application |
| FR2595695B1 (fr) * | 1986-03-12 | 1988-12-02 | Synthelabo | Derives de n-(((hydroxy-2 phenyl) (phenyl) methylene) amino-2) ethyl) acetamide, leur preparation et leur application en therapeutique |
| US5321047A (en) * | 1988-06-03 | 1994-06-14 | John Wyeth & Brother, Limited | Method and amines used therein |
| US5278191A (en) * | 1988-08-31 | 1994-01-11 | G. D. Searle & Co. | Diphenylmethylaminoacetamide derivatives as anti-convulsants |
| US5247121A (en) * | 1989-05-23 | 1993-09-21 | L'oreal | Alkyl esters of n-carboalkyloxy amino-11-undecanoic acids, their processes of preparation and their use as thickening agents |
| FR2647445B1 (fr) * | 1989-05-23 | 1991-08-30 | Oreal | Acides n-carboalkyloxy amino-11 undecanoiques et leurs esters, leurs procedes de preparation et leur utilisation en tant qu'agents epaississants |
| US5210313A (en) * | 1992-01-10 | 1993-05-11 | Maxdem Incorporated | Preparation of 2,5-dichlorobenzophenones |
| IL155710A0 (en) | 2000-11-30 | 2003-11-23 | Pfizer Prod Inc | Combination of gaba agonists and aldose reductase inhibitors |
| IL155704A0 (en) * | 2000-11-30 | 2003-11-23 | Pfizer Prod Inc | Combination of gaba agonists and sorbitol dehydrogenase inhibitors |
| RU2005135454A (ru) * | 2003-05-16 | 2006-06-27 | Пфайзер Продактс Инк. (Us) | Терапевтические комбинации атипичных нейролептиков с модуляторами гамк и/или противосудорожными препаратами |
| EP2354120A1 (en) | 2003-08-20 | 2011-08-10 | XenoPort, Inc. | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof |
| KR101140559B1 (ko) | 2003-08-20 | 2012-07-05 | 제노포트 인코포레이티드 | 아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법 |
| ES2515092T3 (es) | 2003-12-11 | 2014-10-29 | Sunovion Pharmaceuticals Inc. | Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión |
| WO2005082372A1 (en) * | 2004-01-29 | 2005-09-09 | Pfizer Products Inc. | COMBINATION OF γ-AMINOBUTYRIC ACID MODULATORS AND 5-HT 1B RECEPTOR ANTAGONISTS |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| CA2625210A1 (en) * | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2377531A2 (en) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| EP2026813A2 (en) | 2006-05-09 | 2009-02-25 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| CN101466390B (zh) * | 2006-06-15 | 2014-03-12 | 优时比制药有限公司 | 用于治疗难治性癫痫持续状态的肽类化合物 |
| US7998971B2 (en) | 2006-09-08 | 2011-08-16 | Braincells Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| TW200908957A (en) * | 2007-06-15 | 2009-03-01 | Xenoport Inc | Use of prodrugs of GABA analogs, antispasticity agents, and prodrugs of GABAB receptor agonists for treating spasticity |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| WO2011113904A1 (en) | 2010-03-17 | 2011-09-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3371085A (en) * | 1959-12-10 | 1968-02-27 | Hoffmann La Roche | 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones |
| US3966793A (en) * | 1964-06-15 | 1976-06-29 | Clin Midy | Intermediates for preparing 1,4-benzodiazepine-2-ones having a carboxylic acid ester or amide group in the 3-position |
| US3429874A (en) * | 1966-12-22 | 1969-02-25 | Schering Corp | 1-polyhalogenoalkyl-2-oxo-1,3-dihydro-2h-1,4-benzodiazepines |
| IL47712A0 (en) | 1974-08-21 | 1975-10-15 | Sparamedica Ag | Salt of a penicillanic acid derivative,its preparation and pharmaceutical compositions containing it |
| AT348512B (de) * | 1976-08-02 | 1979-02-26 | Hoffmann La Roche | Verfahren zur herstellung von isoindol- derivaten |
-
1975
- 1975-08-01 FR FR7524065A patent/FR2319338A1/fr active Granted
-
1976
- 1976-07-08 NL NLAANVRAGE7607533,A patent/NL170627C/xx not_active IP Right Cessation
- 1976-07-09 IE IE1521/76A patent/IE43143B1/en unknown
- 1976-07-09 ZA ZA764096A patent/ZA764096B/xx unknown
- 1976-07-12 IL IL50019A patent/IL50019A/xx unknown
- 1976-07-12 NZ NZ181444A patent/NZ181444A/xx unknown
- 1976-07-13 CA CA256,882A patent/CA1072112A/en not_active Expired
- 1976-07-16 US US05/705,938 patent/US4094992A/en not_active Expired - Lifetime
- 1976-07-22 MX MX761791U patent/MX4018E/es unknown
- 1976-07-28 AR AR264109A patent/AR211548A1/es active
- 1976-07-28 AT AT556176A patent/AT346312B/de not_active IP Right Cessation
- 1976-07-30 SE SE7608625A patent/SE429651B/xx not_active IP Right Cessation
- 1976-07-30 GB GB31961/76A patent/GB1506808A/en not_active Expired
- 1976-07-30 CH CH976976A patent/CH616148A5/fr not_active IP Right Cessation
- 1976-07-30 NO NO762658A patent/NO142172C/no unknown
- 1976-07-30 PT PT65426A patent/PT65426B/pt unknown
- 1976-07-30 LU LU75514A patent/LU75514A1/xx unknown
- 1976-07-30 DK DK346276A patent/DK346276A/da not_active Application Discontinuation
- 1976-07-30 DE DE19762634288 patent/DE2634288A1/de active Granted
- 1976-07-30 GR GR51384A patent/GR60854B/el unknown
- 1976-07-30 ES ES450300A patent/ES450300A1/es not_active Expired
- 1976-07-30 BE BE169429A patent/BE844737A/xx not_active IP Right Cessation
- 1976-07-30 JP JP51092246A patent/JPS5219644A/ja active Granted
- 1976-07-30 AU AU16450/76A patent/AU496994B2/en not_active Expired
-
1981
- 1981-08-03 US US06/289,148 patent/US4400394A/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| V4 | Discontinued because of reaching the maximum lifetime of a patent |
Free format text: 960708 |