NL170534C - Werkwijze voor het bereiden van 5-fluor 2 methyl 1-(p-methylsulfinylbenzylideen)indeen 3-azijnzuur. - Google Patents

Werkwijze voor het bereiden van 5-fluor 2 methyl 1-(p-methylsulfinylbenzylideen)indeen 3-azijnzuur.

Info

Publication number
NL170534C
NL170534C NLAANVRAGE7415701,A NL7415701A NL170534C NL 170534 C NL170534 C NL 170534C NL 7415701 A NL7415701 A NL 7415701A NL 170534 C NL170534 C NL 170534C
Authority
NL
Netherlands
Prior art keywords
methylsulfinylbenzylidees
fluoro
index
methyl
preparing
Prior art date
Application number
NLAANVRAGE7415701,A
Other languages
English (en)
Other versions
NL7415701A (nl
NL170534B (nl
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US426864A external-priority patent/US3870753A/en
Priority claimed from US05/486,031 external-priority patent/US3970693A/en
Priority claimed from US05/509,602 external-priority patent/US3944600A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL7415701A publication Critical patent/NL7415701A/nl
Publication of NL170534B publication Critical patent/NL170534B/nl
Application granted granted Critical
Publication of NL170534C publication Critical patent/NL170534C/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/455Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/75Reactions with formaldehyde
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/807Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NLAANVRAGE7415701,A 1973-12-20 1974-12-02 Werkwijze voor het bereiden van 5-fluor 2 methyl 1-(p-methylsulfinylbenzylideen)indeen 3-azijnzuur. NL170534C (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US426864A US3870753A (en) 1973-12-20 1973-12-20 Process for preparing indenyl acetic acids
US05/486,031 US3970693A (en) 1974-07-05 1974-07-05 Process for preparing indene acetic acids
US05/509,602 US3944600A (en) 1973-12-20 1974-09-30 Indenylidene-3-acetic acid process for preparing indene acetic acids

Publications (3)

Publication Number Publication Date
NL7415701A NL7415701A (nl) 1975-06-24
NL170534B NL170534B (nl) 1982-06-16
NL170534C true NL170534C (nl) 1982-11-16

Family

ID=27411527

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7415701,A NL170534C (nl) 1973-12-20 1974-12-02 Werkwijze voor het bereiden van 5-fluor 2 methyl 1-(p-methylsulfinylbenzylideen)indeen 3-azijnzuur.

Country Status (16)

Country Link
JP (1) JPS5331153B2 (nl)
AR (2) AR210484A1 (nl)
CA (1) CA1044255A (nl)
CH (1) CH616152A5 (nl)
DD (1) DD116819A5 (nl)
DE (1) DE2462380C2 (nl)
DK (1) DK140835B (nl)
ES (2) ES432921A1 (nl)
FI (1) FI62287C (nl)
FR (1) FR2255060B1 (nl)
GB (1) GB1479519A (nl)
IE (1) IE41529B1 (nl)
NL (1) NL170534C (nl)
NO (2) NO140857C (nl)
SE (2) SE426818B (nl)
YU (2) YU41017B (nl)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732292A (en) * 1970-05-01 1973-05-08 Merck & Co Inc Indenyl compounds
NL7200058A (nl) * 1971-01-21 1972-07-25
US3822310A (en) * 1971-01-21 1974-07-02 Merck & Co Inc Substituted indenyl acetic acids

Also Published As

Publication number Publication date
DK140835C (nl) 1980-04-28
ES432921A1 (es) 1977-03-16
ES455333A1 (es) 1978-05-01
SE440774B (sv) 1985-08-19
AR210484A1 (es) 1977-08-15
JPS5331153B2 (nl) 1978-08-31
IE41529B1 (en) 1980-01-30
NO141892B (no) 1980-02-18
NL7415701A (nl) 1975-06-24
FI348974A (nl) 1975-06-21
SE7415063L (sv) 1975-06-23
DE2462380C2 (de) 1982-11-11
DE2462380A1 (de) 1977-02-10
DK140835B (da) 1979-11-26
SE426818B (sv) 1983-02-14
DE2460292B2 (de) 1977-06-16
NO140857C (no) 1979-11-28
YU41017B (en) 1986-10-31
FI62287C (fi) 1982-12-10
YU331674A (en) 1982-02-28
NO790360L (no) 1975-06-23
FI62287B (fi) 1982-08-31
DD116819A5 (nl) 1975-12-12
JPS5095254A (nl) 1975-07-29
AU7623674A (en) 1976-06-10
NO141892C (no) 1980-05-28
NO744395L (nl) 1975-07-14
IE41529L (en) 1975-06-20
SE8107702L (sv) 1981-12-22
YU55981A (en) 1982-06-30
DE2460292A1 (de) 1975-06-26
CA1044255A (en) 1978-12-12
DK629674A (nl) 1975-08-25
AR206334A1 (es) 1976-07-15
CH616152A5 (en) 1980-03-14
FR2255060B1 (nl) 1978-07-21
NL170534B (nl) 1982-06-16
GB1479519A (en) 1977-07-13
NO140857B (no) 1979-08-20
FR2255060A1 (nl) 1975-07-18

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Legal Events

Date Code Title Description
V4 Discontinued because of reaching the maximum lifetime of a patent