NL161749B - METHOD FOR PREPARING 1- (ACYLOXYALKYL) -5- -PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ON DERIVATIVES AND SALTS THEREOF, AND METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION , MUSCLE-RELAXING SPASMOLYTIC EFFECT, CONTAINING A COMPOUND PREPARED COMPOUND AND THE PHARMACEUTICAL PREPARATION OBTAINED USING THIS METHOD. - Google Patents

METHOD FOR PREPARING 1- (ACYLOXYALKYL) -5- -PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ON DERIVATIVES AND SALTS THEREOF, AND METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION , MUSCLE-RELAXING SPASMOLYTIC EFFECT, CONTAINING A COMPOUND PREPARED COMPOUND AND THE PHARMACEUTICAL PREPARATION OBTAINED USING THIS METHOD.

Info

Publication number
NL161749B
NL161749B NL7007057.A NL7007057A NL161749B NL 161749 B NL161749 B NL 161749B NL 7007057 A NL7007057 A NL 7007057A NL 161749 B NL161749 B NL 161749B
Authority
NL
Netherlands
Prior art keywords
preparing
pharmaceutical preparation
benzodiazepin
acyloxyalkyl
relaxing
Prior art date
Application number
NL7007057.A
Other languages
Dutch (nl)
Other versions
NL161749C (en
NL7007057A (en
Inventor
H Yamamoto
S Inaba
T Hirohashi
M Yamamoto
K Ishizumi
M Akatsu
I Maruyama
Y Kume
K Mori
T Izumi
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of NL7007057A publication Critical patent/NL7007057A/xx
Publication of NL161749B publication Critical patent/NL161749B/en
Application granted granted Critical
Publication of NL161749C publication Critical patent/NL161749C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7007057.A 1969-05-16 1970-05-15 METHOD FOR PREPARING 1- (ACYLOXYALKYL) -5- -PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ON DERIVATIVES AND SALTS THEREOF, AND METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION , MUSCLE-RELAXING SPASMOLYTIC EFFECT, CONTAINING A COMPOUND PREPARED COMPOUND AND THE PHARMACEUTICAL PREPARATION OBTAINED USING THIS METHOD. NL161749C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP44038183A JPS4811718B1 (en) 1969-05-16 1969-05-16

Publications (3)

Publication Number Publication Date
NL7007057A NL7007057A (en) 1970-11-18
NL161749B true NL161749B (en) 1979-10-15
NL161749C NL161749C (en) 1980-03-17

Family

ID=12518255

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7007057.A NL161749C (en) 1969-05-16 1970-05-15 METHOD FOR PREPARING 1- (ACYLOXYALKYL) -5- -PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ON DERIVATIVES AND SALTS THEREOF, AND METHOD FOR PREPARING A PHARMACEUTICAL PREPARATION , MUSCLE-RELAXING SPASMOLYTIC EFFECT, CONTAINING A COMPOUND PREPARED COMPOUND AND THE PHARMACEUTICAL PREPARATION OBTAINED USING THIS METHOD.

Country Status (12)

Country Link
JP (1) JPS4811718B1 (en)
AT (2) AT308125B (en)
BE (1) BE750524A (en)
CA (1) CA946844A (en)
CH (1) CH537396A (en)
CS (1) CS169804B2 (en)
ES (2) ES379701A1 (en)
FR (1) FR2051534B1 (en)
GB (1) GB1272887A (en)
NL (1) NL161749C (en)
SE (1) SE372269B (en)
ZA (1) ZA703130B (en)

Also Published As

Publication number Publication date
DE2023182A1 (en) 1970-11-19
AT308125B (en) 1973-06-25
FR2051534B1 (en) 1974-04-12
GB1272887A (en) 1972-05-03
NL161749C (en) 1980-03-17
ES383587A1 (en) 1973-01-01
CS169804B2 (en) 1976-07-29
ES379701A1 (en) 1972-08-01
CA946844A (en) 1974-05-07
DE2023182B2 (en) 1975-08-28
AT300815B (en) 1972-08-10
NL7007057A (en) 1970-11-18
BE750524A (en) 1970-10-16
SE372269B (en) 1974-12-16
FR2051534A1 (en) 1971-04-09
ZA703130B (en) 1971-01-27
JPS4811718B1 (en) 1973-04-14
CH537396A (en) 1973-05-31

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VJC Lapsed due to non-payment of the due maintenance fee for the patent or patent application
NL80 Information provided on patent owner name for an already discontinued patent

Owner name: SUMITOMO CHEM