AT300815B - Process for the preparation of new benzodiazepine derivatives and of acid addition salts of these compounds - Google Patents

Process for the preparation of new benzodiazepine derivatives and of acid addition salts of these compounds

Info

Publication number
AT300815B
AT300815B AT441670A AT441670A AT300815B AT 300815 B AT300815 B AT 300815B AT 441670 A AT441670 A AT 441670A AT 441670 A AT441670 A AT 441670A AT 300815 B AT300815 B AT 300815B
Authority
AT
Austria
Prior art keywords
compounds
preparation
acid addition
addition salts
benzodiazepine derivatives
Prior art date
Application number
AT441670A
Other languages
German (de)
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Application granted granted Critical
Publication of AT300815B publication Critical patent/AT300815B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT441670A 1969-05-16 1970-05-15 Process for the preparation of new benzodiazepine derivatives and of acid addition salts of these compounds AT300815B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP44038183A JPS4811718B1 (en) 1969-05-16 1969-05-16

Publications (1)

Publication Number Publication Date
AT300815B true AT300815B (en) 1972-08-10

Family

ID=12518255

Family Applications (2)

Application Number Title Priority Date Filing Date
AT1021771A AT308125B (en) 1969-05-16 1970-05-15 Process for the preparation of new benzodiazepine derivatives and of acid addition salts of these compounds
AT441670A AT300815B (en) 1969-05-16 1970-05-15 Process for the preparation of new benzodiazepine derivatives and of acid addition salts of these compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT1021771A AT308125B (en) 1969-05-16 1970-05-15 Process for the preparation of new benzodiazepine derivatives and of acid addition salts of these compounds

Country Status (12)

Country Link
JP (1) JPS4811718B1 (en)
AT (2) AT308125B (en)
BE (1) BE750524A (en)
CA (1) CA946844A (en)
CH (1) CH537396A (en)
CS (1) CS169804B2 (en)
ES (2) ES379701A1 (en)
FR (1) FR2051534B1 (en)
GB (1) GB1272887A (en)
NL (1) NL161749C (en)
SE (1) SE372269B (en)
ZA (1) ZA703130B (en)

Also Published As

Publication number Publication date
AT308125B (en) 1973-06-25
ES379701A1 (en) 1972-08-01
ZA703130B (en) 1971-01-27
NL161749C (en) 1980-03-17
NL7007057A (en) 1970-11-18
DE2023182A1 (en) 1970-11-19
SE372269B (en) 1974-12-16
JPS4811718B1 (en) 1973-04-14
NL161749B (en) 1979-10-15
FR2051534A1 (en) 1971-04-09
CS169804B2 (en) 1976-07-29
CH537396A (en) 1973-05-31
CA946844A (en) 1974-05-07
ES383587A1 (en) 1973-01-01
FR2051534B1 (en) 1974-04-12
GB1272887A (en) 1972-05-03
DE2023182B2 (en) 1975-08-28
BE750524A (en) 1970-10-16

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee