CH537396A - Process for the preparation of new benzodiazepine derivatives and salts thereof - Google Patents

Process for the preparation of new benzodiazepine derivatives and salts thereof

Info

Publication number
CH537396A
CH537396A CH730170A CH730170A CH537396A CH 537396 A CH537396 A CH 537396A CH 730170 A CH730170 A CH 730170A CH 730170 A CH730170 A CH 730170A CH 537396 A CH537396 A CH 537396A
Authority
CH
Switzerland
Prior art keywords
salts
preparation
benzodiazepine derivatives
new benzodiazepine
new
Prior art date
Application number
CH730170A
Other languages
German (de)
Inventor
Yamamoto Hisao
Inaba Shigeho
Hirohashi Toshiyuki
Yamamoto Michiniro
Ishizumi Kikuo
Akatsu Mitsuhiro
Maruyama Isamu
Kume Yoshiharu
Mori Kazuo
Izumi Takahiro
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of CH537396A publication Critical patent/CH537396A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH730170A 1969-05-16 1970-05-15 Process for the preparation of new benzodiazepine derivatives and salts thereof CH537396A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP44038183A JPS4811718B1 (en) 1969-05-16 1969-05-16

Publications (1)

Publication Number Publication Date
CH537396A true CH537396A (en) 1973-05-31

Family

ID=12518255

Family Applications (1)

Application Number Title Priority Date Filing Date
CH730170A CH537396A (en) 1969-05-16 1970-05-15 Process for the preparation of new benzodiazepine derivatives and salts thereof

Country Status (12)

Country Link
JP (1) JPS4811718B1 (en)
AT (2) AT308125B (en)
BE (1) BE750524A (en)
CA (1) CA946844A (en)
CH (1) CH537396A (en)
CS (1) CS169804B2 (en)
ES (2) ES379701A1 (en)
FR (1) FR2051534B1 (en)
GB (1) GB1272887A (en)
NL (1) NL161749C (en)
SE (1) SE372269B (en)
ZA (1) ZA703130B (en)

Also Published As

Publication number Publication date
BE750524A (en) 1970-10-16
NL161749C (en) 1980-03-17
DE2023182A1 (en) 1970-11-19
SE372269B (en) 1974-12-16
CS169804B2 (en) 1976-07-29
AT300815B (en) 1972-08-10
FR2051534B1 (en) 1974-04-12
ZA703130B (en) 1971-01-27
CA946844A (en) 1974-05-07
GB1272887A (en) 1972-05-03
ES383587A1 (en) 1973-01-01
FR2051534A1 (en) 1971-04-09
JPS4811718B1 (en) 1973-04-14
NL7007057A (en) 1970-11-18
DE2023182B2 (en) 1975-08-28
AT308125B (en) 1973-06-25
ES379701A1 (en) 1972-08-01
NL161749B (en) 1979-10-15

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Legal Events

Date Code Title Description
PL Patent ceased