NL156688B - METHOD OF PREPARING A MEDICINAL PRODUCT WITH VASOLICULATING, BLOOD PRESSURE REDUCING AND ANTIARITHMIC ACTIVITY, SO OBTAINED MEDICINAL PRODUCT AND PROCEDURE FOR PREPARING MEDICINAL USE COMPOUNDS. - Google Patents

METHOD OF PREPARING A MEDICINAL PRODUCT WITH VASOLICULATING, BLOOD PRESSURE REDUCING AND ANTIARITHMIC ACTIVITY, SO OBTAINED MEDICINAL PRODUCT AND PROCEDURE FOR PREPARING MEDICINAL USE COMPOUNDS.

Info

Publication number
NL156688B
NL156688B NL7014444.A NL7014444A NL156688B NL 156688 B NL156688 B NL 156688B NL 7014444 A NL7014444 A NL 7014444A NL 156688 B NL156688 B NL 156688B
Authority
NL
Netherlands
Prior art keywords
preparing
medicinal product
medicinal
vasoliculating
antiarithmic
Prior art date
Application number
NL7014444.A
Other languages
Dutch (nl)
Other versions
NL7014444A (en
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of NL7014444A publication Critical patent/NL7014444A/xx
Publication of NL156688B publication Critical patent/NL156688B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL7014444.A 1969-10-01 1970-10-01 METHOD OF PREPARING A MEDICINAL PRODUCT WITH VASOLICULATING, BLOOD PRESSURE REDUCING AND ANTIARITHMIC ACTIVITY, SO OBTAINED MEDICINAL PRODUCT AND PROCEDURE FOR PREPARING MEDICINAL USE COMPOUNDS. NL156688B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE79767 1969-10-01
BE93537 1970-09-03

Publications (2)

Publication Number Publication Date
NL7014444A NL7014444A (en) 1971-04-05
NL156688B true NL156688B (en) 1978-05-16

Family

ID=25647478

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7014444.A NL156688B (en) 1969-10-01 1970-10-01 METHOD OF PREPARING A MEDICINAL PRODUCT WITH VASOLICULATING, BLOOD PRESSURE REDUCING AND ANTIARITHMIC ACTIVITY, SO OBTAINED MEDICINAL PRODUCT AND PROCEDURE FOR PREPARING MEDICINAL USE COMPOUNDS.

Country Status (17)

Country Link
JP (1) JPS541693B1 (en)
AR (1) AR194457A1 (en)
AT (1) AT323135B (en)
CA (1) CA953723A (en)
CH (1) CH542177A (en)
CS (1) CS191158B2 (en)
DK (1) DK147853C (en)
FI (1) FI52714C (en)
FR (1) FR2070102A1 (en)
HU (1) HU167354B (en)
IE (1) IE34545B1 (en)
NL (1) NL156688B (en)
NO (1) NO132865C (en)
OA (1) OA03659A (en)
SE (1) SE384855B (en)
SU (1) SU578860A3 (en)
YU (1) YU35580B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386029A (en) * 1972-03-20 1975-03-05 Smithkline Corp Alpha-benzylamino-4-benzyloxy-3-alkylsulphonylmethyl phenones
DE2862340D1 (en) * 1978-02-01 1983-11-24 Wellcome Found Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
GB2067187B (en) * 1979-12-07 1983-11-30 Cosmos Enterprise Process for the preparation of 1-(4-hydroxyphenyl)-2-(4-benzylpiperidino)-1-propanol and acid addition salts thereof
FR2503705A1 (en) * 1981-04-14 1982-10-15 Synthelabo PHENETHANOLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2508445A1 (en) * 1981-06-29 1982-12-31 Sori Soc Rech Ind NOVEL BENZOYL-PHENYL-PIPERIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE, IN PARTICULAR THERAPEUTICS
FR2534580A1 (en) * 1982-10-13 1984-04-20 Synthelabo PHENYL-1 PIPERIDINO-2 PROPANOL DERIVATIVES, THEIR PREPARATION, AND MEDICINES THAT CONTAIN THEM
FR2537132B1 (en) * 1982-12-06 1987-01-09 Lafon Labor NOVEL SULFUR DERIVATIVES OF 2-AMINO-1-PHENYL-1-ETHANOL, USE IN THERAPEUTICS AND METHOD OF PREPARATION
US5101065A (en) * 1991-02-04 1992-03-31 Imperial Chemical Industries Plc Acetophenone intermediates
FR2741067B1 (en) * 1995-11-10 1997-12-26 Rhone Poulenc Chimie PROCESS FOR ACYLATION OF AN AROMATIC THIOETHER
FR2757160B1 (en) * 1996-12-13 1999-03-12 Sanofi Sa 1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES
GB201714734D0 (en) * 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) * 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1503517A (en) * 1965-04-22 1967-12-01 Bayer Ag Manufacturing process of d - (-) - n-alkyl-1-phenyl-2-aminoethanols

Also Published As

Publication number Publication date
JPS541693B1 (en) 1979-01-27
FI52714C (en) 1977-11-10
NL7014444A (en) 1971-04-05
HU167354B (en) 1975-09-27
NO132865B (en) 1975-10-13
FR2070102A1 (en) 1971-09-10
SU578860A3 (en) 1977-10-30
DK147853B (en) 1984-12-24
FI52714B (en) 1977-08-01
YU238570A (en) 1980-09-25
IE34545L (en) 1971-04-01
OA03659A (en) 1971-12-24
YU35580B (en) 1981-04-30
CS191158B2 (en) 1979-06-29
AT323135B (en) 1975-06-25
NO132865C (en) 1976-01-21
DK147853C (en) 1986-05-20
AR194457A1 (en) 1973-07-23
IE34545B1 (en) 1975-06-11
FR2070102B1 (en) 1974-08-23
CA953723A (en) 1974-08-27
SE384855B (en) 1976-05-24
CH542177A (en) 1973-09-30

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Legal Events

Date Code Title Description
SNR Assignments of patents or rights arising from examined patent applications

Owner name: CONTINENTAL PHARMA, INC.

V1 Lapsed because of non-payment of the annual fee
NL80 Abbreviated name of patent owner mentioned of already nullified patent

Owner name: CONTIN PHARMA