NL162072B - PROCESS FOR PREPARING ANTI-NARCOTIC MEDICINAL PRODUCTS, PREPARED MEDICINAL PRODUCTS SO OBTAINED, AND PROCESS FOR PREPARING SUITABLE ACTIVE SUBSTANCES. - Google Patents

PROCESS FOR PREPARING ANTI-NARCOTIC MEDICINAL PRODUCTS, PREPARED MEDICINAL PRODUCTS SO OBTAINED, AND PROCESS FOR PREPARING SUITABLE ACTIVE SUBSTANCES.

Info

Publication number
NL162072B
NL162072B NL7212176.A NL7212176A NL162072B NL 162072 B NL162072 B NL 162072B NL 7212176 A NL7212176 A NL 7212176A NL 162072 B NL162072 B NL 162072B
Authority
NL
Netherlands
Prior art keywords
medicinal products
preparing
narcotic
active substances
suitable active
Prior art date
Application number
NL7212176.A
Other languages
Dutch (nl)
Other versions
NL162072C (en
NL7212176A (en
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of NL7212176A publication Critical patent/NL7212176A/xx
Publication of NL162072B publication Critical patent/NL162072B/en
Application granted granted Critical
Publication of NL162072C publication Critical patent/NL162072C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/36Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL7212176.A 1971-09-08 1972-09-07 METHOD FOR PREPARING PAIN-RELIEF ANTI-NARCOTIC MEDICINAL PRODUCTS, SO PREPARED MEDICINAL PRODUCTS, AND METHOD FOR PREPARING SUITABLE SUBSTANCES THEREFOR. NL162072C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17883771A 1971-09-08 1971-09-08
US00217633A US3819635A (en) 1971-09-08 1972-01-13 14-hydroxymorphinan derivatives

Publications (3)

Publication Number Publication Date
NL7212176A NL7212176A (en) 1973-03-12
NL162072B true NL162072B (en) 1979-11-15
NL162072C NL162072C (en) 1980-04-15

Family

ID=26874723

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7212176.A NL162072C (en) 1971-09-08 1972-09-07 METHOD FOR PREPARING PAIN-RELIEF ANTI-NARCOTIC MEDICINAL PRODUCTS, SO PREPARED MEDICINAL PRODUCTS, AND METHOD FOR PREPARING SUITABLE SUBSTANCES THEREFOR.

Country Status (19)

Country Link
US (1) US3819635A (en)
JP (1) JPS5310596B2 (en)
AU (1) AU470102B2 (en)
BE (1) BE788478A (en)
CA (1) CA999578A (en)
CH (1) CH590845A5 (en)
CY (1) CY980A (en)
DD (1) DD100255A5 (en)
DE (3) DE2265255C2 (en)
DK (1) DK141624B (en)
FR (1) FR2154481B1 (en)
GB (2) GB1412130A (en)
HK (1) HK2679A (en)
IE (2) IE36687B1 (en)
KE (1) KE2911A (en)
MY (1) MY7900027A (en)
NL (1) NL162072C (en)
SE (2) SE398877B (en)
YU (1) YU45099B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910920A (en) * 1973-11-07 1975-10-07 Bristol Myers Co 3,14,17-Substituted-6,7-tetramethylenemorphinans
US3980641A (en) * 1975-07-31 1976-09-14 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinans
US4017497A (en) * 1975-11-18 1977-04-12 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives
US4058531A (en) * 1976-03-23 1977-11-15 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives
JPS52136176A (en) * 1976-03-23 1977-11-14 Bristol Myers Co Method of improving 144hydroxymorphinan derivatives
US4052389A (en) * 1976-03-23 1977-10-04 Bristol-Myers Company Derivatives of 9,10-dihydroxy-1-(p-alkoxybenzyl)-perhydroisoquinoline oxazine-3-one
US4139534A (en) * 1977-02-17 1979-02-13 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives
GB1587831A (en) * 1977-03-23 1981-04-08 Reckitt & Colmann Prod Ltd Morphine derivatives
GB1593191A (en) * 1977-03-23 1981-07-15 Reckitt & Colmann Prod Ltd Derivatives of morphine
US4115389A (en) * 1977-05-02 1978-09-19 Bristol-Myers Company Process of N-demethylating (-)-1-(p-methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline
US4338320A (en) * 1978-11-15 1982-07-06 The Board Of Regents Of The University Of Nebraska Esters of 6'-hydroxycinchonine, and a method of treating arrythmia with them
US4228285A (en) * 1979-02-28 1980-10-14 Bristol-Myers Company 14-Hydroxy-6-oxamorphinans and 14-hydroxy-6-oxaisomorphinans
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
US4322427A (en) * 1981-04-16 1982-03-30 Bristol-Myers Company Analgetic compositions and methods of use
CA2144770C (en) * 1993-07-19 2006-02-28 Hiroshi Nagase Brain cell protective agent
AU686203B2 (en) * 1993-07-23 1998-02-05 Toray Industries, Inc. Morphinan derivative and medicinal use
CZ281174B6 (en) * 1993-08-13 1996-07-17 Galena, A.S. Process for preparing 3,14beta-dihydroxy-17-normorphinan
DE69917000T2 (en) 1998-02-25 2005-04-21 Abbott Lab BUTORPHANOL-CONTAINING FORMULATIONS WITH DELAYED RELEASE
US20040167164A1 (en) * 1998-05-05 2004-08-26 Jose Pozuelo Compositions and methods for treating particular chemical addictions and mental illnesses
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
EP2987788A1 (en) 2002-05-17 2016-02-24 Taiwanj Pharmaceuticals Co., Ltd. Opioid and opioid-like compounds and uses thereof
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
CN103073496B (en) * 2013-02-18 2015-08-26 苏州立新制药有限公司 The preparation method of Dextromethorphane Hbr
EP3207923B1 (en) 2014-10-14 2019-09-04 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3166559A (en) * 1965-01-19 J-lower alkoxy-x-phenyloxy-ix-hydroxy-
GB1028407A (en) * 1962-04-06 1966-05-04 Shionogi & Co Improvements in or relating to morphinan derivatives and their preparation
FR1362540A (en) * 1963-04-05 1964-06-05 Shionogi & Co Substituted n derivatives of morphinan and their production

Also Published As

Publication number Publication date
CY980A (en) 1979-03-23
YU45099B (en) 1992-07-20
NL162072C (en) 1980-04-15
DE2265256C2 (en) 1985-10-24
AU4622872A (en) 1974-03-07
BE788478A (en) 1973-03-06
JPS4834864A (en) 1973-05-22
IE36688B1 (en) 1977-02-02
SE398877B (en) 1978-01-23
DD100255A5 (en) 1973-09-12
DE2243961A1 (en) 1973-04-05
AU470102B2 (en) 1976-03-04
HK2679A (en) 1979-01-19
DK141624C (en) 1980-10-13
IE36687L (en) 1973-03-08
SE403286B (en) 1978-08-07
IE36687B1 (en) 1977-02-02
KE2911A (en) 1979-01-26
DE2265255C2 (en) 1986-06-05
CA999578A (en) 1976-11-09
DE2243961C2 (en) 1988-07-21
FR2154481B1 (en) 1976-04-23
SE7506292L (en) 1975-06-02
JPS5310596B2 (en) 1978-04-14
DE2265255A1 (en) 1977-01-27
GB1412130A (en) 1975-10-29
GB1412129A (en) 1975-10-29
FR2154481A1 (en) 1973-05-11
YU227772A (en) 1982-02-28
DE2265256A1 (en) 1977-01-27
CH590845A5 (en) 1977-08-31
DK141624B (en) 1980-05-12
MY7900027A (en) 1979-12-31
NL7212176A (en) 1973-03-12
US3819635A (en) 1974-06-25

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Legal Events

Date Code Title Description
V4 Discontinued because of reaching the maximum lifetime of a patent