SE403286B - INTERMEDIATES FOR THE PREPARATION OF 1,4-HYDROXIMORFINAND DERIVATIVES - Google Patents
INTERMEDIATES FOR THE PREPARATION OF 1,4-HYDROXIMORFINAND DERIVATIVESInfo
- Publication number
- SE403286B SE403286B SE7506292A SE7506292A SE403286B SE 403286 B SE403286 B SE 403286B SE 7506292 A SE7506292 A SE 7506292A SE 7506292 A SE7506292 A SE 7506292A SE 403286 B SE403286 B SE 403286B
- Authority
- SE
- Sweden
- Prior art keywords
- hydroximorfinand
- intermediates
- derivatives
- preparation
- hydroximorfinand derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17883771A | 1971-09-08 | 1971-09-08 | |
| US00217633A US3819635A (en) | 1971-09-08 | 1972-01-13 | 14-hydroxymorphinan derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7506292L SE7506292L (en) | 1975-06-02 |
| SE403286B true SE403286B (en) | 1978-08-07 |
Family
ID=26874723
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7211522A SE398877B (en) | 1971-09-08 | 1972-09-06 | PROCEDURE FOR THE PREPARATION OF 14-HYDROXY-MORPHINAND DERIVATIVES |
| SE7506292A SE403286B (en) | 1971-09-08 | 1975-06-02 | INTERMEDIATES FOR THE PREPARATION OF 1,4-HYDROXIMORFINAND DERIVATIVES |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7211522A SE398877B (en) | 1971-09-08 | 1972-09-06 | PROCEDURE FOR THE PREPARATION OF 14-HYDROXY-MORPHINAND DERIVATIVES |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3819635A (en) |
| JP (1) | JPS5310596B2 (en) |
| AU (1) | AU470102B2 (en) |
| BE (1) | BE788478A (en) |
| CA (1) | CA999578A (en) |
| CH (1) | CH590845A5 (en) |
| CY (1) | CY980A (en) |
| DD (1) | DD100255A5 (en) |
| DE (3) | DE2265255C2 (en) |
| DK (1) | DK141624B (en) |
| FR (1) | FR2154481B1 (en) |
| GB (2) | GB1412129A (en) |
| HK (1) | HK2679A (en) |
| IE (2) | IE36687B1 (en) |
| KE (1) | KE2911A (en) |
| MY (1) | MY7900027A (en) |
| NL (1) | NL162072C (en) |
| SE (2) | SE398877B (en) |
| YU (1) | YU45099B (en) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910920A (en) * | 1973-11-07 | 1975-10-07 | Bristol Myers Co | 3,14,17-Substituted-6,7-tetramethylenemorphinans |
| US3980641A (en) * | 1975-07-31 | 1976-09-14 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinans |
| US4017497A (en) * | 1975-11-18 | 1977-04-12 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
| US4139534A (en) * | 1977-02-17 | 1979-02-13 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
| US4058531A (en) * | 1976-03-23 | 1977-11-15 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
| US4052389A (en) * | 1976-03-23 | 1977-10-04 | Bristol-Myers Company | Derivatives of 9,10-dihydroxy-1-(p-alkoxybenzyl)-perhydroisoquinoline oxazine-3-one |
| JPS52136176A (en) * | 1976-03-23 | 1977-11-14 | Bristol Myers Co | Method of improving 144hydroxymorphinan derivatives |
| GB1593191A (en) * | 1977-03-23 | 1981-07-15 | Reckitt & Colmann Prod Ltd | Derivatives of morphine |
| GB1587831A (en) * | 1977-03-23 | 1981-04-08 | Reckitt & Colmann Prod Ltd | Morphine derivatives |
| US4115389A (en) * | 1977-05-02 | 1978-09-19 | Bristol-Myers Company | Process of N-demethylating (-)-1-(p-methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline |
| US4338320A (en) * | 1978-11-15 | 1982-07-06 | The Board Of Regents Of The University Of Nebraska | Esters of 6'-hydroxycinchonine, and a method of treating arrythmia with them |
| US4228285A (en) * | 1979-02-28 | 1980-10-14 | Bristol-Myers Company | 14-Hydroxy-6-oxamorphinans and 14-hydroxy-6-oxaisomorphinans |
| US4272540A (en) * | 1979-04-24 | 1981-06-09 | Sisa, Incorporated | 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them |
| US4322427A (en) * | 1981-04-16 | 1982-03-30 | Bristol-Myers Company | Analgetic compositions and methods of use |
| DE69414085T2 (en) * | 1993-07-19 | 1999-03-18 | Toray Industries, Inc., Tokio/Tokyo | ACTIVE SUBSTANCE TO PROTECT BRAIN CELLS |
| WO1995003308A1 (en) * | 1993-07-23 | 1995-02-02 | Toray Industries, Inc. | Morphinan derivative and medicinal use |
| CZ281174B6 (en) * | 1993-08-13 | 1996-07-17 | Galena, A.S. | Process for preparing 3,14beta-dihydroxy-17-normorphinan |
| CA2321924A1 (en) | 1998-02-25 | 1999-09-02 | Abbott Laboratories | Butorphanol sustained release formulations |
| US20040167164A1 (en) * | 1998-05-05 | 2004-08-26 | Jose Pozuelo | Compositions and methods for treating particular chemical addictions and mental illnesses |
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP1506174B1 (en) | 2002-05-17 | 2015-09-30 | Taiwanj Pharmaceuticals Co., Ltd. | Use of naltrexone for treating kidney and liver damage |
| US8017622B2 (en) * | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| CN103073496B (en) * | 2013-02-18 | 2015-08-26 | 苏州立新制药有限公司 | The preparation method of Dextromethorphane Hbr |
| JP6464181B2 (en) | 2014-10-14 | 2019-02-06 | 久光製薬株式会社 | Patch |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3166559A (en) * | 1965-01-19 | J-lower alkoxy-x-phenyloxy-ix-hydroxy- | ||
| GB1028407A (en) * | 1962-04-06 | 1966-05-04 | Shionogi & Co | Improvements in or relating to morphinan derivatives and their preparation |
| FR1362540A (en) * | 1963-04-05 | 1964-06-05 | Shionogi & Co | Substituted n derivatives of morphinan and their production |
-
0
- BE BE788478D patent/BE788478A/en not_active IP Right Cessation
-
1972
- 1972-01-13 US US00217633A patent/US3819635A/en not_active Expired - Lifetime
- 1972-08-23 CA CA150,036A patent/CA999578A/en not_active Expired
- 1972-09-01 AU AU46228/72A patent/AU470102B2/en not_active Expired
- 1972-09-06 IE IE1213/72A patent/IE36687B1/en unknown
- 1972-09-06 SE SE7211522A patent/SE398877B/en unknown
- 1972-09-06 IE IE103/76A patent/IE36688B1/en unknown
- 1972-09-06 DK DK440172AA patent/DK141624B/en not_active IP Right Cessation
- 1972-09-07 GB GB4161972A patent/GB1412129A/en not_active Expired
- 1972-09-07 FR FR7231816A patent/FR2154481B1/fr not_active Expired
- 1972-09-07 DE DE2265255A patent/DE2265255C2/en not_active Expired
- 1972-09-07 DE DE2265256A patent/DE2265256C2/en not_active Expired
- 1972-09-07 CH CH1315472A patent/CH590845A5/xx not_active IP Right Cessation
- 1972-09-07 DE DE2243961A patent/DE2243961A1/en active Granted
- 1972-09-07 NL NL7212176.A patent/NL162072C/en not_active IP Right Cessation
- 1972-09-07 GB GB1057175A patent/GB1412130A/en not_active Expired
- 1972-09-07 CY CY980A patent/CY980A/en unknown
- 1972-09-07 YU YU227772A patent/YU45099B/en unknown
- 1972-09-07 JP JP8916172A patent/JPS5310596B2/ja not_active Expired
- 1972-09-08 DD DD165557A patent/DD100255A5/xx unknown
-
1975
- 1975-06-02 SE SE7506292A patent/SE403286B/en not_active IP Right Cessation
-
1978
- 1978-12-24 KE KE2911A patent/KE2911A/en unknown
-
1979
- 1979-01-11 HK HK26/79A patent/HK2679A/en unknown
- 1979-12-30 MY MY27/79A patent/MY7900027A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DD100255A5 (en) | 1973-09-12 |
| JPS4834864A (en) | 1973-05-22 |
| IE36688B1 (en) | 1977-02-02 |
| DE2265255A1 (en) | 1977-01-27 |
| DE2243961A1 (en) | 1973-04-05 |
| IE36687B1 (en) | 1977-02-02 |
| GB1412130A (en) | 1975-10-29 |
| CA999578A (en) | 1976-11-09 |
| JPS5310596B2 (en) | 1978-04-14 |
| IE36687L (en) | 1973-03-08 |
| DE2265255C2 (en) | 1986-06-05 |
| YU45099B (en) | 1992-07-20 |
| MY7900027A (en) | 1979-12-31 |
| AU470102B2 (en) | 1976-03-04 |
| FR2154481A1 (en) | 1973-05-11 |
| CH590845A5 (en) | 1977-08-31 |
| CY980A (en) | 1979-03-23 |
| GB1412129A (en) | 1975-10-29 |
| NL162072C (en) | 1980-04-15 |
| DE2243961C2 (en) | 1988-07-21 |
| DE2265256A1 (en) | 1977-01-27 |
| NL7212176A (en) | 1973-03-12 |
| SE398877B (en) | 1978-01-23 |
| BE788478A (en) | 1973-03-06 |
| KE2911A (en) | 1979-01-26 |
| DK141624B (en) | 1980-05-12 |
| DK141624C (en) | 1980-10-13 |
| DE2265256C2 (en) | 1985-10-24 |
| NL162072B (en) | 1979-11-15 |
| US3819635A (en) | 1974-06-25 |
| YU227772A (en) | 1982-02-28 |
| SE7506292L (en) | 1975-06-02 |
| FR2154481B1 (en) | 1976-04-23 |
| AU4622872A (en) | 1974-03-07 |
| HK2679A (en) | 1979-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7506292-7 Effective date: 19921005 Format of ref document f/p: F |