NL149176B - Werkwijze ter bereiding van cef-3-em-4-carbonzuren. - Google Patents

Werkwijze ter bereiding van cef-3-em-4-carbonzuren.

Info

Publication number
NL149176B
NL149176B NL656516708A NL6516708A NL149176B NL 149176 B NL149176 B NL 149176B NL 656516708 A NL656516708 A NL 656516708A NL 6516708 A NL6516708 A NL 6516708A NL 149176 B NL149176 B NL 149176B
Authority
NL
Netherlands
Prior art keywords
cef
preparing
carbonic acids
carbonic
acids
Prior art date
Application number
NL656516708A
Other languages
English (en)
Dutch (nl)
Other versions
NL6516708A (xx
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of NL6516708A publication Critical patent/NL6516708A/xx
Publication of NL149176B publication Critical patent/NL149176B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL656516708A 1964-12-23 1965-12-22 Werkwijze ter bereiding van cef-3-em-4-carbonzuren. NL149176B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB52288/64A GB1141293A (en) 1964-12-23 1964-12-23 Cephemoic acids and derivatives thereof

Publications (2)

Publication Number Publication Date
NL6516708A NL6516708A (xx) 1966-06-24
NL149176B true NL149176B (nl) 1976-04-15

Family

ID=10463355

Family Applications (1)

Application Number Title Priority Date Filing Date
NL656516708A NL149176B (nl) 1964-12-23 1965-12-22 Werkwijze ter bereiding van cef-3-em-4-carbonzuren.

Country Status (9)

Country Link
US (1) US3532694A (xx)
AT (1) AT269352B (xx)
BE (1) BE674255A (xx)
CH (1) CH478135A (xx)
DE (1) DE1545927A1 (xx)
FR (1) FR1461230A (xx)
GB (1) GB1141293A (xx)
NL (1) NL149176B (xx)
SE (1) SE351654B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2073304B1 (xx) * 1969-09-22 1974-08-30 Yamanouchi Pharma Co Ltd
US3864338A (en) * 1970-08-11 1975-02-04 Squibb & Sons Inc Process for the preparation of {66 {hu 2{b -cephalosporin aldehydes
SE412238B (sv) * 1971-05-24 1980-02-25 Ciba Geigy Forfarande for framstellning av 7 beta-amino-cefem-4-karboxylsyraforeningar genom dekarbonylering av en 3-formyl-cefem-4-karboxylsyraforening
ES436565A1 (es) * 1974-06-05 1977-04-01 Bristol Myers Co Un procedimiento para la preparacion de acidos acetamidope- nicilanicos.
GB1571989A (en) * 1976-10-08 1980-07-23 Glaxo Lab Ltd Manufacture of 3-hydroxymethyl cephalosporin compounds
EP0089216A3 (en) * 1982-03-15 1984-11-21 Glaxo Group Limited Cephalosporin compounds
US4584371A (en) * 1984-03-01 1986-04-22 The Upjohn Company Catalytic process for preparing 3-ester-methyl cephalosporins from desacetyl-7-aminocephalosporanic acid
US4908444A (en) * 1986-01-23 1990-03-13 Takeda Chemical Industries, Ltd. Method of producing cephem compounds
US5112967A (en) * 1990-04-27 1992-05-12 Hoffmann-La Roches Inc. Process for synthesizing antibacterial cephalosporin compounds
US5066800A (en) * 1990-04-27 1991-11-19 Hoffmann-La Roche Inc. Qunoline intermediates useful therein for synthesizing antibacterial compounds
US5221739A (en) * 1992-01-09 1993-06-22 Eli Lilly And Company Acetylation of 3-hydroxymethyl cephalosporins
US5512454A (en) * 1994-02-03 1996-04-30 Bristol-Myers Squibb Company Enzymatic acylation of 3-hydroxymethyl cephalosporins
WO1999023098A1 (en) * 1997-10-30 1999-05-14 Bristol-Myers Squibb Company Chemical acetylation of desacetyl-cephalosporins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1012943A (en) * 1961-05-16 1965-12-15 Glaxo Lab Ltd Improvements in or relating to antibiotics
US3270009A (en) * 1961-08-23 1966-08-30 Lilly Co Eli Carbocyclic-substituted aliphatic cephalosporins

Also Published As

Publication number Publication date
US3532694A (en) 1970-10-06
BE674255A (xx) 1966-06-23
FR1461230A (fr) 1966-12-10
GB1141293A (en) 1969-01-29
AT269352B (de) 1969-03-10
SE351654B (xx) 1972-12-04
CH478135A (de) 1969-09-15
NL6516708A (xx) 1966-06-24
DE1545927A1 (de) 1970-01-22

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Legal Events

Date Code Title Description
VJC Lapsed due to non-payment of the due maintenance fee for the patent or patent application
NL80 Abbreviated name of patent owner mentioned of already nullified patent

Owner name: GLAXO