NL147129B - Werkwijze ter bereiding van farmaceutische preparaten met anti-inflammatoire werking, de door toepassing daarvan verkregen voorwerpen, alsmede werkwijze ter bereiding van verbindingen met anti-inflammatoire werking. - Google Patents

Werkwijze ter bereiding van farmaceutische preparaten met anti-inflammatoire werking, de door toepassing daarvan verkregen voorwerpen, alsmede werkwijze ter bereiding van verbindingen met anti-inflammatoire werking.

Info

Publication number
NL147129B
NL147129B NL686800251A NL6800251A NL147129B NL 147129 B NL147129 B NL 147129B NL 686800251 A NL686800251 A NL 686800251A NL 6800251 A NL6800251 A NL 6800251A NL 147129 B NL147129 B NL 147129B
Authority
NL
Netherlands
Prior art keywords
preparation
inflammatory action
compounds
application
pharmaceutical preparations
Prior art date
Application number
NL686800251A
Other languages
English (en)
Other versions
NL6800251A (nl
Original Assignee
Syntex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Corp filed Critical Syntex Corp
Publication of NL6800251A publication Critical patent/NL6800251A/xx
Publication of NL147129B publication Critical patent/NL147129B/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/32—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
    • C07C5/35—Formation of carbon-to-carbon triple bonds only
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/373—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in doubly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/337—Polycyclic acids with carboxyl groups bound to condensed ring systems
    • C07C63/34—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL686800251A 1967-01-13 1968-01-08 Werkwijze ter bereiding van farmaceutische preparaten met anti-inflammatoire werking, de door toepassing daarvan verkregen voorwerpen, alsmede werkwijze ter bereiding van verbindingen met anti-inflammatoire werking. NL147129B (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60899767A 1967-01-13 1967-01-13
US69477167A 1967-12-07 1967-12-07
ZA677597 1967-12-18

Publications (2)

Publication Number Publication Date
NL6800251A NL6800251A (nl) 1968-07-15
NL147129B true NL147129B (nl) 1975-09-15

Family

ID=27417009

Family Applications (2)

Application Number Title Priority Date Filing Date
NL686800251A NL147129B (nl) 1967-01-13 1968-01-08 Werkwijze ter bereiding van farmaceutische preparaten met anti-inflammatoire werking, de door toepassing daarvan verkregen voorwerpen, alsmede werkwijze ter bereiding van verbindingen met anti-inflammatoire werking.
NL7512107A NL7512107A (nl) 1967-01-13 1975-10-15 Werkwijze ter bereiding van farmaceutische pre- paraten met antiinflammatoire werking, de door toepassing daarvan verkregen voorwerpen, alsmede werkwijze ter bereiding van verbindingen met anti-inflammatoire werking.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL7512107A NL7512107A (nl) 1967-01-13 1975-10-15 Werkwijze ter bereiding van farmaceutische pre- paraten met antiinflammatoire werking, de door toepassing daarvan verkregen voorwerpen, alsmede werkwijze ter bereiding van verbindingen met anti-inflammatoire werking.

Country Status (9)

Country Link
BE (1) BE751445Q (nl)
CA (1) CA960689A (nl)
CH (1) CH517690A (nl)
ES (1) ES349061A1 (nl)
FR (3) FR8487M (nl)
GB (1) GB1211134A (nl)
HK (1) HK26776A (nl)
NL (2) NL147129B (nl)
SE (1) SE352069B (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA7068B (en) * 1969-09-30 1971-08-25 Syntex Corp Preparation of 2-(6-methoxy-2-naphrthyl)propionic acid
DE2039639C2 (de) * 1970-08-10 1982-08-05 Syntex Corp., Panama-City Verfahren zur Herstellung von l-2-(6-Methoxy-2-naphthyl)-1-propanol
US4048331A (en) * 1974-10-15 1977-09-13 The Upjohn Company Process of treatment
IT1100784B (it) * 1978-12-06 1985-09-28 Ibis Ist Biochim Speriment Prodotto ad attivita' coleretica e composizioni terapeutiche che lo cmprendno come principio attivo
IT1109200B (it) * 1979-02-20 1985-12-16 Montedison Spa Processo per la preparazione di esteri di acidi arilacetici da alfa-alo-alchilarilchetoni
AT370721B (de) * 1981-02-24 1983-04-25 Ciba Geigy Ag Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der
GB9314693D0 (en) * 1993-07-15 1993-08-25 Smithkline Beecham Plc Naphthyl derivatives for treatment method
CA2487866A1 (en) * 2002-06-07 2003-12-18 Cortical Pty Ltd Napththalene derivatives which inhibit the cytokine or biological activity of macrophage migration inhibitory factor (mif)

Also Published As

Publication number Publication date
CH517690A (de) 1972-01-15
NL7512107A (nl) 1976-01-30
SE352069B (nl) 1972-12-18
NL6800251A (nl) 1968-07-15
FR1587861A (nl) 1970-04-03
BE751445Q (fr) 1970-11-16
GB1211134A (en) 1970-11-04
HK26776A (en) 1976-05-21
FR8487M (nl) 1973-07-27
ES349061A1 (es) 1969-08-16
FR8494M (nl) 1973-07-27
CA960689A (en) 1975-01-07

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Legal Events

Date Code Title Description
SNR Assignments of patents or rights arising from examined patent applications

Owner name: SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED

NL80 Abbreviated name of patent owner mentioned of already nullified patent

Owner name: SYNTEX

V4 Lapsed because of reaching the maximum lifetime of a patent