NL144945B - Werkwijze ter bereiding van derivaten van 7-acylaminocefalosporanzuur. - Google Patents

Werkwijze ter bereiding van derivaten van 7-acylaminocefalosporanzuur.

Info

Publication number
NL144945B
NL144945B NL656507160A NL6507160A NL144945B NL 144945 B NL144945 B NL 144945B NL 656507160 A NL656507160 A NL 656507160A NL 6507160 A NL6507160 A NL 6507160A NL 144945 B NL144945 B NL 144945B
Authority
NL
Netherlands
Prior art keywords
preparing derivatives
acylaminocephalosporanic acid
acylaminocephalosporanic
acid
derivatives
Prior art date
Application number
NL656507160A
Other languages
English (en)
Dutch (nl)
Other versions
NL6507160A (de
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of NL6507160A publication Critical patent/NL6507160A/xx
Publication of NL144945B publication Critical patent/NL144945B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
NL656507160A 1964-06-05 1965-06-04 Werkwijze ter bereiding van derivaten van 7-acylaminocefalosporanzuur. NL144945B (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH733864A CH476021A (de) 1964-06-05 1964-06-05 Verfahren zur Herstellung neuer Derivate der 7-Amino-cephalosporansäure
CH549765 1965-04-21

Publications (2)

Publication Number Publication Date
NL6507160A NL6507160A (de) 1965-12-06
NL144945B true NL144945B (nl) 1975-02-17

Family

ID=25697842

Family Applications (1)

Application Number Title Priority Date Filing Date
NL656507160A NL144945B (nl) 1964-06-05 1965-06-04 Werkwijze ter bereiding van derivaten van 7-acylaminocefalosporanzuur.

Country Status (11)

Country Link
US (1) US3355452A (de)
AT (1) AT264002B (de)
BE (1) BE664955A (de)
BR (1) BR6570169D0 (de)
CH (1) CH476021A (de)
DE (1) DE1545679A1 (de)
ES (1) ES313760A1 (de)
FR (1) FR1463831A (de)
GB (1) GB1073828A (de)
NL (1) NL144945B (de)
SE (1) SE350053B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3497504A (en) * 1968-07-10 1970-02-24 Lilly Co Eli Removal of penicillins from cephalosporins
US3905963A (en) * 1972-01-25 1975-09-16 Lilly Co Eli Process for preparing primary 3-carbamoyloxymethyl cephalosporins
US4210750A (en) * 1972-07-27 1980-07-01 Merck & Co., Inc. Process for the preparation of 3-carbamoyl cephalosporins using isocyanates
US4292427A (en) * 1976-11-17 1981-09-29 Merck & Co., Inc. Cephalosporin compounds
US4252974A (en) * 1978-04-07 1981-02-24 Glaxo Group Limited Cephalosporin compounds
AT368508B (de) * 1978-04-07 1982-10-25 Glaxo Group Ltd Verfahren zur herstellung von 3-carbamoyloxymethylcephalosporinverbindungen
BE878900A (fr) * 1979-04-06 1980-03-20 Glaxo Group Ltd Preparation de cephalosporines substituees par un groupe carbamoyloxymethyle en position 3
US5773435A (en) * 1987-08-04 1998-06-30 Bristol-Myers Squibb Company Prodrugs for β-lactamase and uses thereof
US5338843A (en) * 1992-01-30 1994-08-16 Becton, Dickinson And Company Fluorogenic and chromogenic β-lactamase substrates

Also Published As

Publication number Publication date
ES313760A1 (es) 1966-03-01
US3355452A (en) 1967-11-28
SE350053B (de) 1972-10-16
FR1463831A (fr) 1966-12-30
BE664955A (de)
AT264002B (de) 1968-08-12
DE1545679A1 (de) 1969-08-07
CH476021A (de) 1969-07-31
NL6507160A (de) 1965-12-06
GB1073828A (en) 1967-06-28
BR6570169D0 (pt) 1973-08-16

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