AT264002B - Verfahren zur Herstellung neuer Derivate der 7-Amino-cephalosporansaüre - Google Patents

Verfahren zur Herstellung neuer Derivate der 7-Amino-cephalosporansaüre

Info

Publication number
AT264002B
AT264002B AT510265A AT510265A AT264002B AT 264002 B AT264002 B AT 264002B AT 510265 A AT510265 A AT 510265A AT 510265 A AT510265 A AT 510265A AT 264002 B AT264002 B AT 264002B
Authority
AT
Austria
Prior art keywords
cephalospora
amino
preparation
acid
new derivatives
Prior art date
Application number
AT510265A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Application granted granted Critical
Publication of AT264002B publication Critical patent/AT264002B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
AT510265A 1964-06-05 1965-06-04 Verfahren zur Herstellung neuer Derivate der 7-Amino-cephalosporansaüre AT264002B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH733864A CH476021A (de) 1964-06-05 1964-06-05 Verfahren zur Herstellung neuer Derivate der 7-Amino-cephalosporansäure
CH549765 1965-04-21

Publications (1)

Publication Number Publication Date
AT264002B true AT264002B (de) 1968-08-12

Family

ID=25697842

Family Applications (1)

Application Number Title Priority Date Filing Date
AT510265A AT264002B (de) 1964-06-05 1965-06-04 Verfahren zur Herstellung neuer Derivate der 7-Amino-cephalosporansaüre

Country Status (11)

Country Link
US (1) US3355452A (de)
AT (1) AT264002B (de)
BE (1) BE664955A (de)
BR (1) BR6570169D0 (de)
CH (1) CH476021A (de)
DE (1) DE1545679A1 (de)
ES (1) ES313760A1 (de)
FR (1) FR1463831A (de)
GB (1) GB1073828A (de)
NL (1) NL144945B (de)
SE (1) SE350053B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3497504A (en) * 1968-07-10 1970-02-24 Lilly Co Eli Removal of penicillins from cephalosporins
US3905963A (en) * 1972-01-25 1975-09-16 Lilly Co Eli Process for preparing primary 3-carbamoyloxymethyl cephalosporins
US4210750A (en) * 1972-07-27 1980-07-01 Merck & Co., Inc. Process for the preparation of 3-carbamoyl cephalosporins using isocyanates
US4292427A (en) * 1976-11-17 1981-09-29 Merck & Co., Inc. Cephalosporin compounds
PT69450A (en) * 1978-04-07 1979-05-01 Glaxo Group Ltd Improvements in or relating to cephalosporin compounds
JPS5531064A (en) * 1978-04-07 1980-03-05 Glaxo Group Ltd Improvement on cephalosporin compound
US4258183A (en) * 1979-04-06 1981-03-24 Glaxo Group Limited Process for the preparation of cephalosporin compounds
US5773435A (en) * 1987-08-04 1998-06-30 Bristol-Myers Squibb Company Prodrugs for β-lactamase and uses thereof
US5338843A (en) * 1992-01-30 1994-08-16 Becton, Dickinson And Company Fluorogenic and chromogenic β-lactamase substrates

Also Published As

Publication number Publication date
BR6570169D0 (pt) 1973-08-16
US3355452A (en) 1967-11-28
BE664955A (de)
CH476021A (de) 1969-07-31
NL144945B (nl) 1975-02-17
DE1545679A1 (de) 1969-08-07
FR1463831A (fr) 1966-12-30
GB1073828A (en) 1967-06-28
NL6507160A (de) 1965-12-06
ES313760A1 (es) 1966-03-01
SE350053B (de) 1972-10-16

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