NL139240B - Werkwijze voor het bereiden van 2,4,6-trijoodbenzoezuurderivaten, alsmede van roentgencontrastmiddelen. - Google Patents
Werkwijze voor het bereiden van 2,4,6-trijoodbenzoezuurderivaten, alsmede van roentgencontrastmiddelen.Info
- Publication number
- NL139240B NL139240B NL696906751A NL6906751A NL139240B NL 139240 B NL139240 B NL 139240B NL 696906751 A NL696906751 A NL 696906751A NL 6906751 A NL6906751 A NL 6906751A NL 139240 B NL139240 B NL 139240B
- Authority
- NL
- Netherlands
- Prior art keywords
- trijodenzoic
- preparing
- procedure
- acid derivatives
- contrast agents
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 239000002872 contrast media Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH662568A CH512247A (de) | 1968-05-02 | 1968-05-02 | Neue Röntgenkontrastmittel und Verfahren zu ihrer Herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
NL6906751A NL6906751A (xx) | 1969-11-04 |
NL139240B true NL139240B (nl) | 1973-07-16 |
Family
ID=4312513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL696906751A NL139240B (nl) | 1968-05-02 | 1969-05-02 | Werkwijze voor het bereiden van 2,4,6-trijoodbenzoezuurderivaten, alsmede van roentgencontrastmiddelen. |
Country Status (11)
Country | Link |
---|---|
US (1) | US3883535A (xx) |
JP (1) | JPS4837264B1 (xx) |
AT (2) | AT292724B (xx) |
BE (1) | BE732411A (xx) |
CA (1) | CA931954A (xx) |
CH (1) | CH512247A (xx) |
DE (1) | DE1922613C3 (xx) |
ES (1) | ES366592A1 (xx) |
FR (1) | FR2007674A1 (xx) |
GB (1) | GB1225333A (xx) |
NL (1) | NL139240B (xx) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5142785U (xx) * | 1974-09-25 | 1976-03-30 | ||
DE3000209A1 (de) * | 1980-01-04 | 1981-07-09 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | N-(3-(1'-3''-oxapentamethylenamino-aethylindenamino)-2,4,6-trijodbenzoyl) - (beta) -amino-(alpha) -methylpropionitril, ein verfahren zu dessen herstellung und dessen verwendung als zwischenprodukt |
US5869024A (en) * | 1989-11-29 | 1999-02-09 | Bracco International B.V. | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures |
IL96324A (en) * | 1989-11-29 | 1995-01-24 | Squibb & Sons Inc | History of 5-amino-2,4,6-triadiodo-1,3-benzenecarboxylic acid, processes for their preparation, and methods used as contrast agents |
US5614638A (en) * | 1989-11-29 | 1997-03-25 | Bracco International B.V. | Nonionic radiographic contrast agents |
US5527926A (en) * | 1990-11-26 | 1996-06-18 | Bracco International B.V. | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures |
US5278311A (en) * | 1992-06-05 | 1994-01-11 | E. R. Squibb & Sons, Inc. | Nonionic radiographic contrast agents |
US6051210A (en) | 1997-05-15 | 2000-04-18 | Bracco Research Usa | N,N-dimethyldiatrizoic acid and its conjugates as hepatobiliary agents for X-ray CT imaging |
DE10336716A1 (de) * | 2003-08-11 | 2005-03-10 | Merck Patent Gmbh | Verfahren zur Herstellung von N-Aryl-morpholinonen |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1033777A (en) * | 1963-06-06 | 1966-06-22 | Sterling Drug Inc | Bis-anilide derivatives |
-
1968
- 1968-05-02 CH CH662568A patent/CH512247A/de not_active IP Right Cessation
-
1969
- 1969-03-31 JP JP44023932A patent/JPS4837264B1/ja active Pending
- 1969-04-03 GB GB1225333D patent/GB1225333A/en not_active Expired
- 1969-04-07 US US814193A patent/US3883535A/en not_active Expired - Lifetime
- 1969-04-24 CA CA049611A patent/CA931954A/en not_active Expired
- 1969-04-29 ES ES69366592A patent/ES366592A1/es not_active Expired
- 1969-04-30 AT AT1117469A patent/AT292724B/de not_active IP Right Cessation
- 1969-04-30 BE BE732411D patent/BE732411A/xx unknown
- 1969-04-30 FR FR6913902A patent/FR2007674A1/fr not_active Withdrawn
- 1969-04-30 AT AT420969A patent/AT285041B/de not_active IP Right Cessation
- 1969-05-02 DE DE1922613A patent/DE1922613C3/de not_active Expired
- 1969-05-02 NL NL696906751A patent/NL139240B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA931954A (en) | 1973-08-14 |
JPS4837264B1 (xx) | 1973-11-09 |
US3883535A (en) | 1975-05-13 |
FR2007674A1 (xx) | 1970-01-09 |
NL6906751A (xx) | 1969-11-04 |
AT285041B (de) | 1970-10-12 |
CH512247A (de) | 1971-09-15 |
BE732411A (xx) | 1969-10-30 |
GB1225333A (xx) | 1971-03-17 |
AT292724B (de) | 1971-09-10 |
DE1922613B2 (de) | 1974-08-29 |
DE1922613C3 (de) | 1975-04-03 |
ES366592A1 (es) | 1971-03-16 |
DE1922613A1 (de) | 1969-11-20 |
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