NL1022252A1 - Nieuwe metallo-proteasen met trombospondine domeinen en daarvoor coderende nucleïnezuur samenstellingen. - Google Patents

Nieuwe metallo-proteasen met trombospondine domeinen en daarvoor coderende nucleïnezuur samenstellingen.

Info

Publication number
NL1022252A1
NL1022252A1 NL1022252A NL1022252A NL1022252A1 NL 1022252 A1 NL1022252 A1 NL 1022252A1 NL 1022252 A NL1022252 A NL 1022252A NL 1022252 A NL1022252 A NL 1022252A NL 1022252 A1 NL1022252 A1 NL 1022252A1
Authority
NL
Netherlands
Prior art keywords
proteases
nucleic acid
encoding nucleic
acid compositions
thrombospondin domains
Prior art date
Application number
NL1022252A
Other languages
English (en)
Other versions
NL1022252C2 (nl
Inventor
Renu Anand Heller
Paul Klonowski
Fengrong Zuo
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL1022252A1 publication Critical patent/NL1022252A1/nl
Application granted granted Critical
Publication of NL1022252C2 publication Critical patent/NL1022252C2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
NL1022252A 2000-02-18 2002-12-23 Nieuwe metallo-proteasen met trombospondine domeinen en daarvoor coderende nucle´nezuur samenstellingen. NL1022252C2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18415200P 2000-02-18 2000-02-18
US18415200 2000-02-18

Publications (2)

Publication Number Publication Date
NL1022252A1 true NL1022252A1 (nl) 2003-01-23
NL1022252C2 NL1022252C2 (nl) 2003-11-18

Family

ID=22675774

Family Applications (2)

Application Number Title Priority Date Filing Date
NL1017393A NL1017393C2 (nl) 2000-02-18 2001-02-19 Nieuwe metallo-proteasen met trombospondine domeinen en daarvoor coderende nucleïnezuur samenstellingen.
NL1022252A NL1022252C2 (nl) 2000-02-18 2002-12-23 Nieuwe metallo-proteasen met trombospondine domeinen en daarvoor coderende nucle´nezuur samenstellingen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL1017393A NL1017393C2 (nl) 2000-02-18 2001-02-19 Nieuwe metallo-proteasen met trombospondine domeinen en daarvoor coderende nucleïnezuur samenstellingen.

Country Status (4)

Country Link
BE (1) BE1014089A4 (nl)
CA (1) CA2332533A1 (nl)
IE (1) IE20010121A1 (nl)
NL (2) NL1017393C2 (nl)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2296766C (en) * 1997-07-25 2010-03-16 Du Pont Pharmaceuticals Company Aggrecan degrading metallo proteases
US6391610B1 (en) * 1999-08-06 2002-05-21 The Cleveland Clinic Foundation Nucleic acids encoding zinc metalloproteases
WO2001042468A1 (en) * 1999-12-09 2001-06-14 Lexicon Genetics Incorporated Human adam-ts proteases and polynucleotides encoding the same
CA2434953A1 (en) * 2001-01-31 2002-08-08 Incyte Genomics, Inc. Protein modification and maintenance molecules

Also Published As

Publication number Publication date
NL1022252C2 (nl) 2003-11-18
NL1017393A1 (nl) 2001-08-22
NL1017393C2 (nl) 2003-01-09
CA2332533A1 (en) 2001-08-18
BE1014089A4 (fr) 2003-04-01
IE20010121A1 (en) 2002-12-11

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Legal Events

Date Code Title Description
AD1A A request for search or an international type search has been filed
RD2N Patents in respect of which a decision has been taken or a report has been made (novelty report)

Effective date: 20030917

PD2B A search report has been drawn up
VD1 Lapsed due to non-payment of the annual fee

Effective date: 20050901