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Priority claimed from DE200810003556external-prioritypatent/DE102008003556A1/en
Priority claimed from DE200810025007external-prioritypatent/DE102008025007A1/en
Application filed by Sanofi Aventis DeutschlandfiledCriticalSanofi Aventis Deutschland
Publication of MY155338ApublicationCriticalpatent/MY155338A/en
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Abstract
THE INVENTION RELATES TO NOVEL INSULIN ANALOGS HAVING A BASAL TIME-ACTION PROFILE, WHICH ARE CHARACTERIZED BY THE ADDITION AND/OR SUBTITUTION OF NEGATIVELY AND POSITIVELY CHARGED AMINO ACID RESIDUES AND BY AN AMIDATION OF THE C-TERMINAL CARBOXY GROUP OF THE B CHAIN AND HISTIDINE IN POSITION 8 OF THE INSULIN A CHAIN. THE INVENTION ALSO RELATES TO THE PRODUCTION AND USE THEREOF.
MYPI2010002667A2008-01-092009-01-06Novel insulin derivatives having an extremely delayed time-action profile
MY155338A
(en)