MY144635A - 2-oxo-1,2,4,5-tetrahydro-1,-3-benzodiazepin-3-yl-piperidines used as cgrp antagonists - Google Patents

2-oxo-1,2,4,5-tetrahydro-1,-3-benzodiazepin-3-yl-piperidines used as cgrp antagonists

Info

Publication number
MY144635A
MY144635A MYPI20061292A MYPI20061292A MY144635A MY 144635 A MY144635 A MY 144635A MY PI20061292 A MYPI20061292 A MY PI20061292A MY PI20061292 A MYPI20061292 A MY PI20061292A MY 144635 A MY144635 A MY 144635A
Authority
MY
Malaysia
Prior art keywords
benzodiazepin
tetrahydro
oxo
cgrp antagonists
salts
Prior art date
Application number
MYPI20061292A
Inventor
Stephan Georg Mueller
Fabio Paleari
Klaus Rudolf
Philipp Lustenberger
Dirk Stenkamp
Alexander Dreyer
Kirsten Arndt
Gerhard Schaenzle
Henri Doods
Marco Santagostino
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ARP050101139A external-priority patent/AR049625A1/en
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MY144635A publication Critical patent/MY144635A/en

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)

Abstract

THE PRESENT INVENTION RELATES TO NEW CGRP ANTAGONISTS OF GENERAL FORMULA I WHEREIN B, R1 AND R2 ARE DEFINED AS IN CLAIM 1, THE TAUTOMERS, THE ISOMERS, THE DIASTEREOMERS, THE ENANTIORNERS, THE HYDRATES, THE MIXTURES THEREOF AND THE SALTS THEREOF AS WELL AS THE HYDRATES OF THE SALTS, PARTICULARLY THE PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF WITH INORGANIC OR ORGANIC ACIDS OR BASES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM.
MYPI20061292A 2005-03-23 2006-03-23 2-oxo-1,2,4,5-tetrahydro-1,-3-benzodiazepin-3-yl-piperidines used as cgrp antagonists MY144635A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ARP050101139A AR049625A1 (en) 2004-03-29 2005-03-23 CGRP ANTAGONISTS, PROCEDURE FOR PREPARATION AS WELL AS ITS USE AS A MEDICINAL PRODUCT
PE2005000336A PE20060150A1 (en) 2004-03-29 2005-03-23 SELECTED CGRP ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND PROCEDURE FOR THEIR PREPARATION
PCT/EP2005/003094 WO2005092880A1 (en) 2004-03-29 2005-03-23 Selected cgrp antagonists, methods for the production thereof and their use as medicaments

Publications (1)

Publication Number Publication Date
MY144635A true MY144635A (en) 2011-10-14

Family

ID=43298656

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20061292A MY144635A (en) 2005-03-23 2006-03-23 2-oxo-1,2,4,5-tetrahydro-1,-3-benzodiazepin-3-yl-piperidines used as cgrp antagonists

Country Status (2)

Country Link
MY (1) MY144635A (en)
PE (1) PE20061453A1 (en)

Also Published As

Publication number Publication date
PE20061453A1 (en) 2007-01-19

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