MY129832A - Substituted thiophenes, processes for their preparation, their use as medicament or diagnostic and medicament comprising them - Google Patents
Substituted thiophenes, processes for their preparation, their use as medicament or diagnostic and medicament comprising themInfo
- Publication number
- MY129832A MY129832A MYPI20032052A MYPI20032052A MY129832A MY 129832 A MY129832 A MY 129832A MY PI20032052 A MYPI20032052 A MY PI20032052A MY PI20032052 A MYPI20032052 A MY PI20032052A MY 129832 A MY129832 A MY 129832A
- Authority
- MY
- Malaysia
- Prior art keywords
- medicament
- disorders
- treatment
- diagnostic
- processes
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SUBSTITUTED THIOPHENE, PROCESSES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENT OR DIAGNOSTIC AND MEDICAMENT COMPRISING THEMTHE INVENTION RELATES TO SUBSTITUTED THIOPHENE DERIVATIVES OF THE FORMULA 1, WHERE R1 TO R8 ARE AS DEFINED IN THE CLAIMS.MEDICAMENTS COMPRISING COMPOUNDS OF THIS TYPE ARE OF USE FOR PREVENTING OR TREATING VARIOUS DISORDERS. THUS, THE COMPOUNDS CAN BE USED, INTER ALIA, FOR THE TREATMENT OF RESPIRATORY DISORDERS AND SNORING, AND FOR IMPROVING THE RESPIRATORY DRIVE, FOR THE TREATMENT OF ACUTE AND CHRONIC DISORDERS, DISORDERS INDUCED BY ISCHEMIC AND/OR REPERFUSION EVENTS AND BY PROLIFERATIVE OR FIBROTIC EVENTS, FOR THE TREATMENT OR PROPHYLAXIS OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM AND LIPID METABOLISM, AND DIABETES, BLOOD COAGULATION AND INFECTION BY PARASITES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10224892A DE10224892A1 (en) | 2002-06-04 | 2002-06-04 | Substituted thiophenes, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY129832A true MY129832A (en) | 2007-05-31 |
Family
ID=29557542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20032052A MY129832A (en) | 2002-06-04 | 2003-06-03 | Substituted thiophenes, processes for their preparation, their use as medicament or diagnostic and medicament comprising them |
Country Status (33)
| Country | Link |
|---|---|
| EP (1) | EP1513834B1 (en) |
| JP (1) | JP4511924B2 (en) |
| KR (1) | KR101087966B1 (en) |
| CN (1) | CN1324024C (en) |
| AR (1) | AR040239A1 (en) |
| AT (1) | ATE320425T1 (en) |
| AU (1) | AU2003273553B2 (en) |
| BR (1) | BR0311548A (en) |
| CA (1) | CA2488242C (en) |
| CR (1) | CR7577A (en) |
| DE (2) | DE10224892A1 (en) |
| DK (1) | DK1513834T3 (en) |
| EC (1) | ECSP045471A (en) |
| ES (1) | ES2258722T3 (en) |
| HK (1) | HK1076460A1 (en) |
| HR (1) | HRP20041153A2 (en) |
| IL (1) | IL165519A (en) |
| MA (1) | MA27204A1 (en) |
| ME (1) | MEP27608A (en) |
| MX (1) | MXPA04011986A (en) |
| MY (1) | MY129832A (en) |
| NO (1) | NO329351B1 (en) |
| OA (1) | OA12827A (en) |
| PE (1) | PE20040534A1 (en) |
| PL (1) | PL372589A1 (en) |
| PT (1) | PT1513834E (en) |
| RS (1) | RS51141B (en) |
| RU (1) | RU2315766C2 (en) |
| TN (1) | TNSN04240A1 (en) |
| TW (1) | TWI283675B (en) |
| UA (1) | UA77551C2 (en) |
| WO (1) | WO2003101984A1 (en) |
| ZA (1) | ZA200409095B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10323701A1 (en) | 2003-05-22 | 2004-12-23 | Aventis Pharma Deutschland Gmbh | Process for the synthesis of heterocyclic compounds |
| US20040242560A1 (en) | 2003-05-22 | 2004-12-02 | Aventis Pharma Deutschland Gmbh | Process for synthesizing heterocyclic compounds |
| US7632970B2 (en) | 2003-06-30 | 2009-12-15 | Sumitomo Chemical Company, Limited | Asymmetric urea compound and process for producing asymmetric compound by asymmetric conjugate addition reaction with the same as catalyst |
| JP2010507664A (en) * | 2006-10-25 | 2010-03-11 | 武田薬品工業株式会社 | Benzimidazole compounds |
| JP5745406B2 (en) | 2008-09-02 | 2015-07-08 | サノフイ | Substituted aminoindanes and analogs thereof, and pharmaceutical uses thereof |
| CA2780031A1 (en) * | 2009-11-12 | 2011-05-19 | Selvita S.A. | A compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent |
| RU2518740C1 (en) * | 2013-03-22 | 2014-06-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" | METHOD, INHIBITING Na+/H+-EXCHANGE, AND DIHYDROCHLORIDE OF 2-(3,4-METHYLENEDIOXYPHENYL)-9-MORPHOLINOETHYLIMIDAZO[1,2-a]BENZIMIDAZOLE |
| LT3173408T (en) | 2014-07-25 | 2018-12-27 | Taisho Pharmaceutical Co., Ltd. | Phenyl tetrahydroisoquinoline compound substituted with heteroaryl |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE754935A (en) * | 1969-08-13 | 1971-02-17 | Hoechst Ag | 2- (THIENYL-3'-AMINO) -1,3-DIAZACYCLOALCENES AND THEIR PREPARATION |
| BR6915362D0 (en) * | 1969-08-16 | 1973-01-04 | Hoechst Ag | PROCESS FOR THE PREPARATION OF 2 (TIENIL-3-AMINO) 1,3-DIAZACYCLEALCHENE |
| DE2830279A1 (en) * | 1978-07-10 | 1980-01-31 | Boehringer Sohn Ingelheim | 2-CORNER CLAMP ON N- (2'-CHLOR-4'-METHYL-THIENYL-3 ') - N- (CYCLOPROPYLMETHYL) - AMINO CORNER CLAMP ON-IMIDAZOLINE- (2), THE ACID ADDITION SALTS THAT IT INCLUDES HIS PRODUCTION |
| EP1100506A4 (en) * | 1998-07-29 | 2002-06-26 | Merck & Co Inc | Integrin receptor antagonists |
| DE19960204A1 (en) * | 1999-12-14 | 2001-06-28 | Aventis Pharma Gmbh | Substituted norlbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them |
| CA2480638C (en) * | 2002-03-29 | 2013-02-12 | Chiron Corporation | Substituted benzazoles and use thereof as raf kinase inhibitors |
-
2002
- 2002-06-04 DE DE10224892A patent/DE10224892A1/en not_active Withdrawn
-
2003
- 2003-05-26 MX MXPA04011986A patent/MXPA04011986A/en active IP Right Grant
- 2003-05-26 CN CNB038128462A patent/CN1324024C/en not_active Expired - Fee Related
- 2003-05-26 RU RU2004138812/04A patent/RU2315766C2/en not_active IP Right Cessation
- 2003-05-26 EP EP03740148A patent/EP1513834B1/en not_active Expired - Lifetime
- 2003-05-26 PT PT03740148T patent/PT1513834E/en unknown
- 2003-05-26 JP JP2004509675A patent/JP4511924B2/en not_active Expired - Fee Related
- 2003-05-26 AU AU2003273553A patent/AU2003273553B2/en not_active Ceased
- 2003-05-26 RS YUP-1038/04A patent/RS51141B/en unknown
- 2003-05-26 ME MEP-276/08A patent/MEP27608A/en unknown
- 2003-05-26 UA UA20041211000A patent/UA77551C2/en unknown
- 2003-05-26 DK DK03740148T patent/DK1513834T3/en active
- 2003-05-26 OA OA1200400321A patent/OA12827A/en unknown
- 2003-05-26 ES ES03740148T patent/ES2258722T3/en not_active Expired - Lifetime
- 2003-05-26 WO PCT/EP2003/005465 patent/WO2003101984A1/en active IP Right Grant
- 2003-05-26 PL PL03372589A patent/PL372589A1/en not_active Application Discontinuation
- 2003-05-26 BR BR0311548-8A patent/BR0311548A/en not_active IP Right Cessation
- 2003-05-26 DE DE50302673T patent/DE50302673D1/en not_active Expired - Lifetime
- 2003-05-26 KR KR1020047019725A patent/KR101087966B1/en not_active IP Right Cessation
- 2003-05-26 AT AT03740148T patent/ATE320425T1/en active
- 2003-05-26 CA CA2488242A patent/CA2488242C/en not_active Expired - Fee Related
- 2003-05-30 PE PE2003000531A patent/PE20040534A1/en not_active Application Discontinuation
- 2003-06-02 TW TW092114860A patent/TWI283675B/en not_active IP Right Cessation
- 2003-06-02 AR ARP030101958A patent/AR040239A1/en active IP Right Grant
- 2003-06-03 MY MYPI20032052A patent/MY129832A/en unknown
-
2004
- 2004-11-10 ZA ZA200409095A patent/ZA200409095B/en unknown
- 2004-11-16 MA MA27952A patent/MA27204A1/en unknown
- 2004-11-19 CR CR7577A patent/CR7577A/en unknown
- 2004-12-02 EC EC2004005471A patent/ECSP045471A/en unknown
- 2004-12-02 IL IL165519A patent/IL165519A/en not_active IP Right Cessation
- 2004-12-03 HR HR20041153A patent/HRP20041153A2/en not_active Application Discontinuation
- 2004-12-03 TN TNP2004000240A patent/TNSN04240A1/en unknown
- 2004-12-16 NO NO20045504A patent/NO329351B1/en not_active IP Right Cessation
-
2005
- 2005-09-23 HK HK05108392A patent/HK1076460A1/en not_active IP Right Cessation
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