MY109719A - Long-acting biodegradable microparticles and a process for their preparation. - Google Patents

Long-acting biodegradable microparticles and a process for their preparation.

Info

Publication number
MY109719A
MY109719A MYPI92000482A MYPI19920482A MY109719A MY 109719 A MY109719 A MY 109719A MY PI92000482 A MYPI92000482 A MY PI92000482A MY PI19920482 A MYPI19920482 A MY PI19920482A MY 109719 A MY109719 A MY 109719A
Authority
MY
Malaysia
Prior art keywords
long
preparation
biodegradable microparticles
acting
acting biodegradable
Prior art date
Application number
MYPI92000482A
Inventor
Jurgen Sandow Dr
Norbert Lill Dr
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of MY109719A publication Critical patent/MY109719A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Abstract

LONG-ACTING BIODEGRADABLE MICROPARTICLES CONTAINING THERAPEUTICALLY ACTIVE PEPTIDES AS THE ACTIVE SUBSTANCE AND POLY (LACTIDE-CO-GLYCOLIDE) AS THE CARRIER MATERIAL ARE DESCRIBED WHICH ARE OBTAINED BY SPRAY DRYING AT TEMPERATURES BELOW 60?C AT A SPRAY FLOW RATE OF ABOVE 500 NL/H.
MYPI92000482A 1991-03-25 1992-03-23 Long-acting biodegradable microparticles and a process for their preparation. MY109719A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4109746 1991-03-25

Publications (1)

Publication Number Publication Date
MY109719A true MY109719A (en) 1997-05-31

Family

ID=6428150

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI92000482A MY109719A (en) 1991-03-25 1992-03-23 Long-acting biodegradable microparticles and a process for their preparation.

Country Status (20)

Country Link
EP (1) EP0505966B1 (en)
JP (1) JP3346789B2 (en)
KR (1) KR100203253B1 (en)
AT (1) ATE124254T1 (en)
AU (1) AU653210B2 (en)
CA (1) CA2063883C (en)
CY (1) CY2032A (en)
CZ (1) CZ284756B6 (en)
DE (1) DE59202649D1 (en)
DK (1) DK0505966T3 (en)
ES (1) ES2076592T3 (en)
FI (1) FI99084C (en)
HR (1) HRP940838B1 (en)
IE (1) IE67555B1 (en)
IL (1) IL101346A0 (en)
MY (1) MY109719A (en)
NO (1) NO302856B1 (en)
NZ (1) NZ242073A (en)
YU (1) YU48420B (en)
ZA (1) ZA922130B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0535937B2 (en) * 1991-10-01 2008-05-21 Takeda Chemical Industries, Ltd. Prolonged release microparticle preparation and production of the same
JP2651320B2 (en) * 1992-07-16 1997-09-10 田辺製薬株式会社 Method for producing sustained-release microsphere preparation
AU4198793A (en) * 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
WO1994009898A1 (en) * 1992-10-26 1994-05-11 Schwarz Pharma Ag Method of manufacturing microcapsules
GB9423419D0 (en) * 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
CA2192782C (en) * 1995-12-15 2008-10-14 Nobuyuki Takechi Production of microspheres
CA2192773C (en) 1995-12-15 2008-09-23 Hiroaki Okada Production of sustained-release preparation for injection
KR100321854B1 (en) * 1998-12-30 2002-08-28 동국제약 주식회사 Long-term sustained-release microspheres containing luteinizing hormone releasing hormone homologues and a method of producing the same
CN1520313A (en) 2001-05-23 2004-08-11 ������ҩ��ʽ���� Compsns. for promoting healing of bone racture
WO2002094320A1 (en) 2001-05-23 2002-11-28 Tanabe Seiyaku Co., Ltd. Therapeutic compositions for repairing chondropathy
CA2490351C (en) 2002-06-25 2011-11-01 Takeda Pharmaceutical Company Limited Process for producing sustained-release composition
US7625865B2 (en) 2004-03-26 2009-12-01 Universita Degli Studi Di Parma Insulin highly respirable microparticles
KR100722607B1 (en) 2006-05-11 2007-05-28 주식회사 펩트론 A process of preparing microspheres for sustained release having improved dispersibility and syringeability
FR2934856B1 (en) * 2008-08-05 2010-08-13 Servier Lab NEW PROCESS FOR OBTAINING THE V-CRYSTALLINE FORM OF AGOMELATIN
BR102012011209A2 (en) * 2012-05-11 2014-03-25 Bioactive Biomateriais Ltda BIODEGRADABLE THREE-DIMENSIONAL MATERIAL AND BIODEGRADABLE THREE-DIMENSIONAL MATERIAL PREPARATION PROCESS
CN105963258B (en) * 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 Preparation method of sustained-release particles
CN105963257B (en) * 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 Preparation method of sustained-release particles
CN109985585A (en) * 2019-05-13 2019-07-09 苏州岸谷纳米技术有限公司 A kind of fast preparation method of Biodegradable high molecular microballoon

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962091A (en) * 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
PT85521B (en) * 1986-08-11 1990-06-29 Innovata Biomed Ltd METHOD FOR PREPARING PHARMACEUTICAL COMPOSITIONS CONTAINING MICROCAPSULES
DE3710175A1 (en) * 1987-02-12 1988-08-25 Hoechst Ag MULTI-PIECE IMPLANTABLE MEDICINE PREPARATION WITH LONG-TERM EFFECT
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
DE3738228A1 (en) * 1987-11-11 1989-05-24 Hoechst Ag METHOD FOR PRODUCING BIODEGRADABLE MICRO-CAPSULES OF WATER-SOLUBLE PEPTIDES AND PROTEINS AND MICRO-CAPSULES OBTAINED BY THIS PROCESS
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier

Also Published As

Publication number Publication date
KR100203253B1 (en) 1999-06-15
IL101346A0 (en) 1992-11-15
HRP940838A2 (en) 1997-06-30
CA2063883C (en) 2001-12-11
KR920017645A (en) 1992-10-21
YU48420B (en) 1998-07-10
IE67555B1 (en) 1996-04-17
FI921248A0 (en) 1992-03-23
CY2032A (en) 1998-02-20
NO921147D0 (en) 1992-03-24
DK0505966T3 (en) 1995-10-30
AU653210B2 (en) 1994-09-22
NO302856B1 (en) 1998-05-04
JPH0570363A (en) 1993-03-23
ES2076592T3 (en) 1995-11-01
EP0505966A1 (en) 1992-09-30
ZA922130B (en) 1992-11-25
FI99084B (en) 1997-06-30
CZ284756B6 (en) 1999-02-17
IE920956A1 (en) 1992-10-07
ATE124254T1 (en) 1995-07-15
JP3346789B2 (en) 2002-11-18
EP0505966B1 (en) 1995-06-28
CS88792A3 (en) 1992-10-14
NZ242073A (en) 1993-08-26
YU26392A (en) 1994-12-28
FI99084C (en) 1997-10-10
CA2063883A1 (en) 1992-09-26
AU1310992A (en) 1992-10-01
DE59202649D1 (en) 1995-08-03
NO921147L (en) 1992-09-28
HRP940838B1 (en) 2000-12-31
FI921248A (en) 1992-09-26

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