MXPA06014579A - Regimenes de progestina ciclicos y equipos. - Google Patents
Regimenes de progestina ciclicos y equipos.Info
- Publication number
- MXPA06014579A MXPA06014579A MXPA06014579A MXPA06014579A MXPA06014579A MX PA06014579 A MXPA06014579 A MX PA06014579A MX PA06014579 A MXPA06014579 A MX PA06014579A MX PA06014579 A MXPA06014579 A MX PA06014579A MX PA06014579 A MXPA06014579 A MX PA06014579A
- Authority
- MX
- Mexico
- Prior art keywords
- daily dosage
- dosage units
- progestin
- active agent
- phase
- Prior art date
Links
- 239000000583 progesterone congener Substances 0.000 title claims abstract description 72
- -1 Cyclic progestin Chemical class 0.000 title claims description 16
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims abstract description 60
- 239000013543 active substance Substances 0.000 claims abstract description 33
- PYVFWTPEBMRKSR-UHFFFAOYSA-N tanaproget Chemical compound CN1C(C#N)=CC=C1C1=CC=C(NC(=S)OC2(C)C)C2=C1 PYVFWTPEBMRKSR-UHFFFAOYSA-N 0.000 claims abstract description 25
- 238000000034 method Methods 0.000 claims abstract description 15
- 229950001471 tanaproget Drugs 0.000 claims abstract description 5
- 239000000902 placebo Substances 0.000 claims description 25
- 229940068196 placebo Drugs 0.000 claims description 25
- 239000003814 drug Substances 0.000 claims description 14
- 229960002985 medroxyprogesterone acetate Drugs 0.000 claims description 10
- PSGAAPLEWMOORI-PEINSRQWSA-N medroxyprogesterone acetate Chemical compound C([C@@]12C)CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2CC[C@]2(C)[C@@](OC(C)=O)(C(C)=O)CC[C@H]21 PSGAAPLEWMOORI-PEINSRQWSA-N 0.000 claims description 10
- 150000002148 esters Chemical class 0.000 claims description 9
- WWYNJERNGUHSAO-XUDSTZEESA-N (+)-Norgestrel Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 WWYNJERNGUHSAO-XUDSTZEESA-N 0.000 claims description 8
- UWFYSQMTEOIJJG-FDTZYFLXSA-N cyproterone acetate Chemical compound C1=C(Cl)C2=CC(=O)[C@@H]3C[C@@H]3[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(C)=O)(OC(=O)C)[C@@]1(C)CC2 UWFYSQMTEOIJJG-FDTZYFLXSA-N 0.000 claims description 8
- 229960000978 cyproterone acetate Drugs 0.000 claims description 8
- RPLCPCMSCLEKRS-BPIQYHPVSA-N desogestrel Chemical compound C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 RPLCPCMSCLEKRS-BPIQYHPVSA-N 0.000 claims description 8
- 229960004976 desogestrel Drugs 0.000 claims description 7
- CHNXZKVNWQUJIB-CEGNMAFCSA-N ethisterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 CHNXZKVNWQUJIB-CEGNMAFCSA-N 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000012730 sustained-release form Substances 0.000 claims description 6
- 238000013268 sustained release Methods 0.000 claims description 5
- RWBRUCCWZPSBFC-RXRZZTMXSA-N (20S)-20-hydroxypregn-4-en-3-one Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@@H](O)C)[C@@]1(C)CC2 RWBRUCCWZPSBFC-RXRZZTMXSA-N 0.000 claims description 4
- ISHXLNHNDMZNMC-VTKCIJPMSA-N (3e,8r,9s,10r,13s,14s,17r)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol Chemical compound O/N=C/1CC[C@@H]2[C@H]3CC[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C\1 ISHXLNHNDMZNMC-VTKCIJPMSA-N 0.000 claims description 4
- DBPWSSGDRRHUNT-UHFFFAOYSA-N 17alpha-hydroxy progesterone Natural products C1CC2=CC(=O)CCC2(C)C2C1C1CCC(C(=O)C)(O)C1(C)CC2 DBPWSSGDRRHUNT-UHFFFAOYSA-N 0.000 claims description 4
- DBPWSSGDRRHUNT-CEGNMAFCSA-N 17α-hydroxyprogesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(O)[C@@]1(C)CC2 DBPWSSGDRRHUNT-CEGNMAFCSA-N 0.000 claims description 4
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- ICTXHFFSOAJUMG-SLHNCBLASA-N Norethynodrel Chemical compound C1CC(=O)CC2=C1[C@H]1CC[C@](C)([C@](CC3)(O)C#C)[C@@H]3[C@@H]1CC2 ICTXHFFSOAJUMG-SLHNCBLASA-N 0.000 claims description 4
- 229940022663 acetate Drugs 0.000 claims description 4
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- AZFLJNIPTRTECV-FUMNGEBKSA-N dienogest Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@](CC3)(O)CC#N)CC3)C3=C21 AZFLJNIPTRTECV-FUMNGEBKSA-N 0.000 claims description 4
- 229960003309 dienogest Drugs 0.000 claims description 4
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58604504P | 2004-07-07 | 2004-07-07 | |
| PCT/US2005/023955 WO2006014476A1 (en) | 2004-07-07 | 2005-07-06 | Cyclic progestin regimens and kits |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA06014579A true MXPA06014579A (es) | 2007-03-01 |
Family
ID=35064935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA06014579A MXPA06014579A (es) | 2004-07-07 | 2005-07-06 | Regimenes de progestina ciclicos y equipos. |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20060009428A1 (https=) |
| EP (1) | EP1773344A1 (https=) |
| JP (2) | JP5288796B2 (https=) |
| CN (2) | CN104208067A (https=) |
| AR (1) | AR049707A1 (https=) |
| AU (1) | AU2005269938A1 (https=) |
| BR (1) | BRPI0512991A (https=) |
| CA (1) | CA2571377C (https=) |
| MX (1) | MXPA06014579A (https=) |
| PA (1) | PA8638601A1 (https=) |
| PE (1) | PE20060378A1 (https=) |
| SV (1) | SV2006002165A (https=) |
| TW (1) | TW200603813A (https=) |
| WO (1) | WO2006014476A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US6391907B1 (en) * | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
| US6509334B1 (en) * | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| UA73119C2 (en) * | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| US20060009428A1 (en) | 2004-07-07 | 2006-01-12 | Wyeth | Cyclic progestin regimens and kits |
| GT200500185A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
| MX2007013467A (es) * | 2005-04-28 | 2008-01-21 | Wyeth Corp | Tanaproget micronizado y composiciones que contienen el mismo. |
| CN101166532B (zh) | 2005-04-28 | 2011-06-22 | 惠氏公司 | 微粒化的他那普戈特、组合物及其制备方法 |
| CN101166521A (zh) * | 2005-04-28 | 2008-04-23 | 惠氏公司 | 通过湿制粒法制备包含微粒化他那普戈特的组合物 |
| CA2610767C (en) * | 2005-06-09 | 2014-09-23 | Wyeth | Tanaproget compositions containing ethinyl estradiol |
| US10137135B2 (en) | 2005-08-15 | 2018-11-27 | Allergan Sales, Llc | Formulations and methods for providing progestin-only contraception while minimizing adverse side effects associated therewith |
| US20070093548A1 (en) * | 2005-10-25 | 2007-04-26 | Wyeth | Use of progesterone receptor modulators |
| DE102006050558B4 (de) | 2006-10-26 | 2009-03-26 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System enthaltend Norelgestromin zur Kontrazeption und Hormonsubstitution |
| BRPI0819571A2 (pt) | 2007-12-20 | 2019-09-24 | Teva Womenss Health Inc | "método para contracepção de emergência, pacote farmacêutico para contracepção de emergência e composição farmacêutica" |
| DE102008022221A1 (de) * | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
| WO2010042610A1 (en) | 2008-10-08 | 2010-04-15 | Agile Therapeutics, Inc. | Transdermal delivery |
| WO2010042607A1 (en) | 2008-10-08 | 2010-04-15 | Agile Therapeutics, Inc | Transdermal delivery |
| WO2010042612A1 (en) | 2008-10-08 | 2010-04-15 | Agile Therapeutics, Inc. | Transdermal delivery |
| EP2410859A4 (en) | 2009-03-27 | 2013-03-13 | Agile Therapeutics Inc | TRANSDERMAL ADMINISTRATION |
| EP3689364A1 (en) * | 2010-02-08 | 2020-08-05 | Shenzhen Evergreen Therapeutics Co., Ltd. | Methods for the use of progestogen as a glucocorticoid sensitizer |
| US10849857B2 (en) | 2010-07-28 | 2020-12-01 | Laboratorios Leon Farma Sa | Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same |
| US11351122B1 (en) | 2010-07-28 | 2022-06-07 | Laboratorios Leon Farma Sa | Synthetic progestogens and pharmaceutical compositions comprising the same |
| AR081670A1 (es) | 2010-06-29 | 2012-10-10 | Leon Farma Sa Lab | Composicion farmaceutica que comprende drospirenona y kit anticonceptivo |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| EP2730284A1 (en) * | 2012-11-12 | 2014-05-14 | Naari AG | Levonorgestrel-only-composition for optimized oral contraception with defined levonorgestrel content, dosage regimen and pharmaceutical preparation |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| CA2989975C (en) * | 2015-06-23 | 2021-10-12 | Laboratorios Leon Farma Sa | Drospirenone-based contraceptive for a female patient affected with excess weight |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| CN107982520A (zh) * | 2017-12-25 | 2018-05-04 | 上海交通大学医学院附属第九人民医院 | 外源性MPA与hMG在制备动物模型药物中的应用 |
| US11679114B2 (en) | 2021-07-26 | 2023-06-20 | Navad Life Sciences Pte | Progestogen-only oral contraception |
| WO2024218800A1 (en) * | 2023-04-21 | 2024-10-24 | Akums Drugs And Pharmaceuticals Limited | Vaginal drug delivery system of dydrogesterone |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AU581486B2 (en) * | 1985-12-30 | 1989-02-23 | Warner-Lambert Company | Graduated estrogen contraceptive |
| AU630334B2 (en) * | 1987-09-24 | 1992-10-29 | Jencap Research Ltd. | Hormone preparations for hormone replacement therapy and contraceptive method |
| KR100518102B1 (ko) * | 1996-07-26 | 2005-10-04 | 와이어쓰 | 프로게스틴과 에스트로겐의 혼합물을 포함하는 단일상 피임약 키트 |
| WO2001030355A1 (fr) * | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation |
| WO1999051214A2 (en) * | 1998-04-07 | 1999-10-14 | Akzo Nobel N.V. | Progestogen-only contraceptive kit |
| US6509334B1 (en) * | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
| US6444668B1 (en) * | 1999-05-04 | 2002-09-03 | Wyeth | Combination regimens using progesterone receptor modulators |
| US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
| SG120970A1 (en) * | 1999-05-04 | 2006-04-26 | Ligand Pharm Inc | Cyclothiocarbamate derivatives as progesterone receptor modulators |
| UA77150C2 (en) * | 1999-08-31 | 2006-11-15 | Schering Ag | Use of mesoprogestins j867, j912, or j1042 for female contraception, pharmaceutical composition and kit (variants) |
| UA73119C2 (en) * | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
| JP2005535628A (ja) * | 2002-06-25 | 2005-11-24 | ワイス | Ｐｒモジュレーターとしてのシクロチオカルバメート誘導体 |
| US20060009428A1 (en) | 2004-07-07 | 2006-01-12 | Wyeth | Cyclic progestin regimens and kits |
| GT200500186A (es) | 2004-07-07 | 2006-03-02 | Regimenes anticonceptivos con antagonistas del receptor de progesterona y kits | |
| GT200500185A (es) | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
| GT200500183A (es) | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos |
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2005
- 2005-07-06 US US11/174,592 patent/US20060009428A1/en not_active Abandoned
- 2005-07-06 TW TW094122827A patent/TW200603813A/zh unknown
- 2005-07-06 CN CN201410381416.2A patent/CN104208067A/zh active Pending
- 2005-07-06 CN CNA2005800227796A patent/CN1980676A/zh active Pending
- 2005-07-06 AR ARP050102805A patent/AR049707A1/es unknown
- 2005-07-06 PE PE2005000783A patent/PE20060378A1/es not_active Application Discontinuation
- 2005-07-06 JP JP2007520464A patent/JP5288796B2/ja not_active Expired - Fee Related
- 2005-07-06 PA PA20058638601A patent/PA8638601A1/es unknown
- 2005-07-06 EP EP05768415A patent/EP1773344A1/en not_active Ceased
- 2005-07-06 BR BRPI0512991-5A patent/BRPI0512991A/pt not_active IP Right Cessation
- 2005-07-06 SV SV2005002165A patent/SV2006002165A/es not_active Application Discontinuation
- 2005-07-06 AU AU2005269938A patent/AU2005269938A1/en not_active Abandoned
- 2005-07-06 CA CA2571377A patent/CA2571377C/en not_active Expired - Fee Related
- 2005-07-06 WO PCT/US2005/023955 patent/WO2006014476A1/en not_active Ceased
- 2005-07-06 MX MXPA06014579A patent/MXPA06014579A/es active IP Right Grant
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2010
- 2010-05-03 US US12/772,280 patent/US8604027B2/en not_active Expired - Fee Related
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2012
- 2012-09-27 JP JP2012214378A patent/JP2013040181A/ja active Pending
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2013
- 2013-11-08 US US14/074,946 patent/US20140094458A1/en not_active Abandoned
Also Published As
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|---|---|
| PA8638601A1 (es) | 2006-07-03 |
| US20100292198A1 (en) | 2010-11-18 |
| CN1980676A (zh) | 2007-06-13 |
| AU2005269938A1 (en) | 2006-02-09 |
| WO2006014476A1 (en) | 2006-02-09 |
| CN104208067A (zh) | 2014-12-17 |
| US20060009428A1 (en) | 2006-01-12 |
| JP2013040181A (ja) | 2013-02-28 |
| SV2006002165A (es) | 2006-05-09 |
| JP2008505909A (ja) | 2008-02-28 |
| US8604027B2 (en) | 2013-12-10 |
| PE20060378A1 (es) | 2006-06-02 |
| CA2571377A1 (en) | 2006-02-09 |
| BRPI0512991A (pt) | 2008-04-22 |
| EP1773344A1 (en) | 2007-04-18 |
| AR049707A1 (es) | 2006-08-30 |
| CA2571377C (en) | 2014-03-25 |
| US20140094458A1 (en) | 2014-04-03 |
| TW200603813A (en) | 2006-02-01 |
| JP5288796B2 (ja) | 2013-09-11 |
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