MXPA06010251A - Treatment of keratinous tissue - Google Patents

Abstract

A method of treating keratinous tissue is disclosed. The treatment utilizes at least one topical composition for application to keratinous tissue, a sachet containing the topical composition and a receptacle with heating system for releasably receiving at least one sachet.

Description

TREATMENT OF QUERAT1NOSO TISSUE FIELD OF THE INVENTION This invention relates to a method for treating keratinous tissue. In the treatment at least one topical composition is used to apply to the keratinous tissue, a bag containing the topical composition and a receptacle with heating system to receive at least one bag so that it can be released.

BACKGROUND OF THE INVENTION Many topical products that are available to consumers are primarily intended to improve the health and / or physical appearance of the skin. Many of these skin care products are intended to slow down, minimize or even eliminate wrinkles, skin discoloration and other histological changes generally associated with skin aging or damage that the environment causes. in the human skin. Other products that are applied topically are pharmaceutical products, developed to treat specific diseases through the keratinous tissue. Consumers prefer topical products since they are not only effective but also pleasant to use. The experience of topical application improves when the product applied topically is warm or hot. For example, when a moisturizing lotion that has been moderately heated is applied to the skin of the face or body, users perceive a more pleasant sensation than when applying a cold lotion. Therefore, the experience of applying the lotion becomes a factor that • motivates the use of the lotion and it is applied more frequently than if the cold lotion were applied. With the regular use of products of topical application the maximum benefit of the assets is obtained. The viscosity of many topical compositions is reduced when the composition is moderately heated. The reduction in viscosity can make the composition flow more easily on the skin, hair or nails. Vaseline is an example of this type of product. By heating the vaseline it becomes less viscous and the user can apply a thinner layer with less force. When vaseline cools, it regains its original rheology and a thin, but full, layer remains on the surface on which it was applied. Obviously, it is possible for topical compositions to become so thin that they are aesthetically unpleasant, more difficult to apply, and that upon spilling, they quickly soil the surrounding area. For these reasons, it is important that the temperature to which the topical compositions are heated is within a controlled range. This controlled interval varies depending on the specific composition that is heated.

It is known to provide fluid products from receptacles for the purpose of warming or heating products that are applied topically. However, many products applied topically are easily degraded by heat, especially by constant heat. In addition, considerable time is needed to heat the entire product in a large receptacle. Currently, users of lotions often spend little time on their personal care and when they are in a hurry they can skip the step of moderately heating the product. The heaters for fluid-filled containers are known in the industry. These heaters include a heating structure that receives energy by means of electrical outlets that are connected to the electric current outputs. Based on the foregoing, there is a continuing need to provide topical compositions that provide a pleasant moderate heat and which at the same time can be prepared quickly and easily used.

BRIEF DESCRIPTION OF THE INVENTION This application describes a method for treating keratinous tissue.

As a first step, the method comprises the use of a receptacle for heating a topical composition contained in a sack. The receptacle comprises: walls defining a cavity into which a bag is releasably placed; a heating system associated with one or more of a wall of the cavity; and a power source operatively associated with the heating system. The energy source supplies the heating system with sufficient energy to moderately heat the composition within the bag to a sufficient predicted temperature so that the composition is easy to apply to the keratinous tissue, but is not so fluid as to glide over the surface when it is applied Generally, the temperature is about 30 ° C to 65 ° C. Once the composition is heated moderately, it is removed from the bag and applied to the keratinous tissue. In addition, the application describes a receptacle for moderately heating a topical composition contained in a sack. The receptacle comprises walls defining a cavity into which at least one pouch is releasably disposed; and a heating system associated with one or more of a wall of the cavity. The heating system reaches and maintains a predicted temperature for the topical composition. In one embodiment, the heating system is activated when the bag is inserted. In another embodiment, the receptacle is controlled by a regulator such that when a predicted and appropriate temperature is reached for applying the topical composition, the heating system maintains that temperature for a predetermined period. Finally, the receptacle comprises an energy source operatively associated with the heating system to supply energy to that system.

A case for treating keratinous tissue is also described. The kit comprises at least one topical composition, at least one bag comprising surfaces defining one or more chambers for containing the composition and a receptacle into which at least one bag is releasably disposed. The receptacle comprises walls defining a cavity in which one or several sacks are releasably positioned, a heating system associated with one or more than one wall; and a power source operatively associated with the heating system. When the bag is placed in the pocket of the receptacle, the composition is moderately heated. Herein is also described a regimen for skin care; the regime comprises the following steps: selecting a sack between several sacks, placing the sack so that it can be released in a receptacle as described above, and activating the heating system operatively associated with the receptacle to moderately heat the composition contained therein. coat. Once it is moderately heated, the bag opens and the warm composition is applied to the skin of a user. Optionally, but preferably, this regime is met at least once a day.

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1a is a perspective view of one embodiment of a receptacle with an inserted bag. Figure 1b is a right side view of the embodiment of the Figure 1a, without the sack. Figure 1c is a planar top view of the embodiment of Figure 1a. Figure 1d is an exploded view of the embodiment of Figure 1a, without the bag. Figure 2a is a front view of a second embodiment of a battery receptacle. Figure 2b is a right side view of the embodiment of Figure 2a. Figure 2c is a cross-sectional view of the embodiment of Figure 2a taken along line A-A. Figure 2d is a planar top view of the embodiment of Figure 2a. Figure 2e is a planar rear view of the embodiment of Figure 2a. Figure 3a is a perspective view of a third embodiment of a receptacle in which a plurality of sacks are placed.

Figure 3b is a planar top view of the embodiment illustrated in Figure 3a. Figure 4a is a perspective view of a fourth embodiment of a receptacle inserted in a docking station. Figure 4b is a planar top view of the receptacle with the coupling station illustrated in Figure 4a. Figure 4c is a cross-sectional view of the receptacle with the docking station illustrated in Figure 4a taken along line A-A of Figure 4b. Figure 4d is a plan view of the left side of the receptacle with the coupling station illustrated in Figure 4a. Figure 4e is a front flat view of the receptacle with the docking station illustrated in Figure 4a. Figure 5a is a front plan view of a first embodiment of a sack. Figure 5b is a perspective view of a bag as shown in Figure 5a. Figure 5c is a bottom plan view of a bag as shown in Figure 5a. Figure 5d is a right side view of a bag as shown in Figure 5a. Figure 5e is a cross-sectional view of the bag illustrated in Figure 5a, taken along line A-A of Figure 5b.

Figure 6a is a front plan view of a second embodiment of a sack having two chambers. Figure 6b is a cross-sectional view of a sack as shown in Figure 6a taken along line A-A and showing the compositions contained therein. Figure 7a is a front plan view of a third embodiment of the bag that also has two chambers. Figure 7b is a left side view of the embodiment of Figure 7a. Figure 7c is a perspective view of the embodiment illustrated in Figure 7a. Figure 8a is a front plan view of a fourth embodiment of a bag having a contact point for activating the heating system. Figure 8b is a side view of the bag of Figure 8a. Figure 8c is a perspective view of the bag of Figure 8a. Figure 9a is a perspective view of a fourth embodiment of a receptacle having two heating elements and two heat sinks. Figure 9b is a front plan view of the mode of the Figure 9a. Figure 9c is a cross-sectional view of the embodiment of Figure 9a, taken along line B-B of Figure 9b.

DETAILED DESCRIPTION OF THE INVENTION All percentages and proportions used herein are by weight of the total composition and all measurements were made at 25 ° C, unless otherwise indicated. The compositions of the present invention can comprise, consist or consist essentially of the essential components, as well as of the optional ingredients described herein. As used herein, the term "consists essentially of" means that the composition or component may include additional ingredients, but only if they do not materially alter the basic and novel characteristics of the claimed compositions or methods. The term "keratinous tissue", as used herein, refers to keratin-containing layers arranged as the outer protective layer of mammals which include, but are not limited to, the skin, hair, nails, cuticles, the hooves, the lips, etc. The term "topical application", as used herein, means applying or extending the compositions of the present invention to the surface of the keratinous tissue. The term "dermatologically acceptable", as used herein, means that the compositions or components described are suitable for use in contact with the keratinous tissue of mammals without excessive toxicity, incompatibility, instability, allergic reaction, and the like occurring. . The term "flexible", as used herein, means "that can be folded, flattened, deformed or bent easily with the hand or with the fingers". The term "rigid", as used herein, means "that it can not be folded, flattened, deformed or bent easily with the hand or with the fingers". The term "heating system", as used herein, refers to all components used to transfer energy from the energy source to the contents of the bag or to indicate the time when the expected temperature is reached. Examples are the heating element associated with the wall of the cavity adjacent to the power source and various other components. The term "regulator", as used herein, refers to a device that controls all functions of the heating system. The term "microprocessor", as used herein, refers to a computer whose complete central processing unit (CPU) is contained in an integrated chip or in a plurality of integrated chips. The term "microcontroller", as used herein, refers to a microprocessor in a single integrated circuit intended to operate as an integrated system. In addition to a CPU, a microcontroller typically includes a minimum amount of RAM and PROM, timers, and input / output. The term "heat sink", as used herein, refers to a piece of thermal conductive material designed to absorb, distribute or transmit heat from a heat source. The term "sack", as used herein, refers to a small container or bag having liquid impervious walls, which can be filled with a composition and which contains a topical composition or ingredient. The term "unit dose", as used herein, refers to a sufficient amount of the composition for a single application or treatment. The term "safe and effective amount", as used herein, means a compound or composition sufficient to induce significantly a positive benefit, preferably a benefit of appearance or feel to the keratinous tissue, including independently or in combination the benefits described herein. , but low enough to avoid serious collateral effects (ie to provide a reasonable ratio of benefit to risk, within the scope of the reasonable opinion of the experienced technician). The term "timer", as used herein, refers to a clock that measures a time interval and issues an alert at the end of that interval. It can also act as the regulator that starts / activates or stops / deactivates a mechanism or process at a predetermined time. The term "projection", as used herein, refers to a projection, that is, to a part projecting from the body of an object such as a sack. The term "point of contact," as used herein, refers to any portion of the bag that activates the heating system by means of contact with a switch. The term "operatively associated", as used herein, means linking or connecting one element to another to produce an appropriate effect.

Topical composition The compositions used in the present invention are applied topically. The topical compositions described are useful for regulating keratinous tissue. It is often necessary to regulate the conditions of the keratinous tissue, especially those of the human skin caused by situations that can be induced or caused by factors internal and / or external to the body. For example, "regulating the skin" includes prophylactically and / or therapeutically regulating the condition of the skin, and may produce one or more of the following benefits: increased volume (i.e., epidermal and / or dermal layers are formed). the skin and / or subcutaneous layers such as fat and muscle and, where appropriate, the keratinous layers of the nail and the hair shaft) to reduce atrophy (eg of the skin); increased circumvolution of the boundary between the dermis and the epidermis; and reduction of discoloration of skin without melanin, p. ex. reduction of dark circles, spotting (eg, irregular reddish coloration due to, eg, rosacea) (hereinafter referred to as "reddish spots"), paleness (pale or yellowish color), discoloration caused by telangiectasia or arachnoid vascularizations, discolorations produced by melanin (eg, pigment spots, senile spots, uneven pigmentation, hyperpigmentation such as hyperpigmentation after inflammation) and other chromophores in the skin (eg lipofuscin, protein crosslinks such as those produced with glycation, and the like). As used herein, prophylactically regulating skin disorders includes retarding, minimizing and / or preventing visible discontinuities and / or skin touch (e.g., irregularities in texture, fine lines, wrinkles, sagging). , striae, adiposis of the skin, ocular swelling, and the like that can be detected visually or with touch). As used in the present, regulate • therapeutically the condition of the skin includes improving (eg, decreasing, minimizing and / or erasing) discontinuities in the skin). Regulating skin disorders involves improving the appearance or touch of the skin. As used herein, the term "regulate the condition of the skin" is intended to include the regulation of these signs without considering the mechanism of origin. To provide a benefit in the appearance or feel imparted to the skin, hair or nails a large variety of amounts of the compositions of the present invention may be used. The amounts of the compositions of the present typically applied in a single application range, in milligrams of composition per square centimeter of the skin referred to herein as "mg / cm2", from about 0.1 mg / cm2 to about 20 mg / cm2. An especially useful application amount is from about 0.5 mg / cm2 to about 10 mg / cm2.

Active In one embodiment of the invention, the composition comprises at least one active ingredient. The active ingredient can be an asset for skin care. Active ingredients that can be selected include the statements below. Mixtures of these ingredients can also be used. Optionally, the compositions may comprise a safe and effective amount of an active. The examples of assets that can be included are listed below. These actives are preferably included at a concentration of from about 0.0001% to about 20%, more preferably from about 0.05% to about 5% and even more preferably from about 0.1% to about 2%, by weight of the composition. The exceptions to these preferred concentrations are those mentioned for the conditioning agents and peptides that are specified below. Assets may have more than one mechanism of action, therefore their location in specific categories does not necessarily cover their entire range of activity. Non-limiting examples of assets useful in the present invention include: Assets 1. Desquamation assets An example of a desquamation asset is salicylic acid. Other examples are the? -hydroxy acids (eg, glycolic acid, lactic acid) and? -ceto acids (eg pyruvic acid). 2. Anti-acne assets Examples of useful anti-acne assets include resorcinol, sulfur, erythromycin, zinc and dehydroacetic acid. Some additional examples of anti-acne actives are described in more detail in U.S. Pat. no. 5,607,980. 3. Anti-wrinkle / active antiatrophy assets Illustrative anti-wrinkle / anti-thyrotropic agents suitable for use in the compositions of the present invention include hydroxy acids (eg, salicylic acid, glycolic acid), keto acids (eg, pyruvic acid), ascorbic acid (vitamin C), phytic acid, lysophosphatidic acid, flavonoids (eg isoflavones, flavones, etc.), stilbenes, cinnamates, resveratrol, kinetin, zeatin, dimethylaminoethanol, synthetic peptides, peptides from natural sources (eg soy peptides) ), acid salts of sugars (eg Mn gluconate), retinoids (eg retinyl propionate), vitamin B compounds (eg thiamin (vitamin B1), niacinamide (vitamin B3), panthenol and pantothenic acid (vitamin B5), pyridoxine (vitamin B6), carnitine (vitamin Bt), riboflavin (vitamin B2), and its derivatives and salts (eg, salts of HCl or calcium)). 4. Antioxidants / Radical scavengers Non-limiting examples of antioxidants / radical scavengers useful in the present invention include ascorbic acid (vitamin C) and its salts, fatty acid ascorbyl esters, ascorbic acid derivatives (eg magnesium phosphate) and ascorbyl), tocopherol (vitamin E), tocopherol sorbate, tocopherol acetate, other tocopherol esters, butylated hydroxybenzoic acids and their salts (eg butylated hydroxytoluene commonly known as BHT), 6-hydroxy-2,5 acid , 7,8-tetramethylchroman-2-carboxylic acid, amines (eg N, N-diethylhydroxylamine, amino guanidine), nordhydroguaracetic acid, bioflavonoids, amino acids, sillmarin, tea extracts and extracts of rind / grape seed. Preferred antioxidants / radical scavengers are selected from grape skin / seed extracts, tea extracts and tocopherol esters, more preferably tocopherol acetate.

. Chelating Agents Illustrative chelating agents that are useful herein are described in U.S. Pat. no. 5,487,884. 6. Flavonoids Flavonoids are widely described in U.S. Pat. num. 5,686,082 and 5,686,367. Examples of flavonoids particularly suitable for use in the present invention are one or more flavones, one or more chalcones, one or more flavanones (eg hesperidin), one or more isoflavones, one or more coumarins, one or more chromones, one or more dicumaroles, one or more chromanones, one or more chromanols, isomers (eg, cis / trans isomers) thereof, derivatives thereof, and mixtures thereof. Flavones and soflavones, in particular daidzein (7,4'-dihydroxy isoflavone), genistein (5,7,4'-trihydroxy isoflavone), equol (7,4'-), are preferred for use in the present invention. dihydroxy isoflavone), 5,7-dihydroxy-4'-methoxy isoflavone, soy isoflavones (a mixture extracted from soybeans), and mixtures thereof. 7. Anti-inflammatory A steroidal anti-inflammatory agents include, but are not limited to corticosteroids such as hydrocortisone. A second class of anti-inflammatory agents useful in these compositions includes non-steroidal anti-inflammatory agents. The varieties of compounds included in this group are well known to those with experience in the industry. Specific nonsteroidal anti-inflammatory agents and useful in the composition of the invention include, but are not limited to, salicylates, flufenamic acid, etofenamate, aspirin, and mixtures thereof.

Additional antiinflammatory agents useful herein include allantoin and licorice compounds (the plant / species genus of the family Glycyrrhiza glabra), including glycyrrhizic acid, glycyrrhizic acid, and derivatives (eg, salts and esters). 8. Antiadiposis Agents The compositions of the present invention may optionally comprise a safe and effective amount of an anti-cellulitis agent. Suitable agents may include, but are not limited to, xanthine compounds (e.g., caffeine, theophylline, theobromine, and aminophylline). 9. Active tanning agents A preferred active tanning agent is dihydroxyacetone.

. Skin lightening agents Suitable skin lightening agents include those known in the industry, including oxic acid, arbutin, tranexamic acid, ascorbic acid and derivatives thereof (eg ascorbyl magnesium phosphate or sodium ascorbyl phosphate). , ascorbyl glucoside, and the like). Other skin lightening materials suitable for use herein include Actiwhite® (Cognis), Emblica® (Roña), Azeloglycine (Sinerga), Sepiwhite, hexamidine, amino sugars (eg N-acetylglucosamine), phytosterols (e.g. eg, one or more sitosterols, stigmasterol, campesterole, brassicasterol, etc.) and extracts (eg, blackberry extract). 11. Antimicrobial and Antifungal Assets Preferred examples of active ingredients useful herein include those selected from the group consisting of salicylic acid, benzoyl peroxide, 3-hydroxybenzoic acid, glycolic acid, lactic acid, 4-hydroxybenzoic acid, acetylsalicylic acid, -hydroxybutanoic acid, 2-hydroxypentanoic acid, 2-hydroxyhexanoic acid, cis-retnoic acid, trans-retinoic acid, retinol, phytic acid, N-acetyl-L-cysteine, lipoic acid, azelaic acid, arachidonic acid, benzoyl peroxide, tetracycline , ibuprofen, naproxen, hydrocortisone, acetaminophen, resorcinol, phenoxyethanol, phenoxypropanol, phenoxyisopropanol, 2,4,4, -trichloro-2'-hydroxydiphenyl ether, 3,4,4'-trichlorocarbanillda, octopirox, lidocaine hydrochloride, clotrimazole, miconazole , ketoconazole, neocicin sulfate, and mixtures thereof. 12. Sunscreen assets The right sun protection assets can be organic or inorganic. Sagarin et al., In Chapter VIII, pages 189 and subsequent pages of "Cosmetics Science and Technology (1972)", presents numerous suitable assets. Other assets are mentioned in Annex VII of "The European Union Cosmetics Directive 76/768 / EEC" (Cosmetic Directive 76/768 / EEC of the European Union). Non-limiting examples of suitable sunscreen agents include octinoxate, avobenzone, oxybenzone, octocrylene, octisalate, homosalate, meradimate, ensulizol, zinc oxide, titanium dioxide, and mixtures of these compounds. 13. Conditioning agents The compositions of the present invention may comprise a conditioning agent selected from the group comprising humectants, moisturizers, hair conditioners or skin conditioners, including emollients. A variety of these materials can be used and each of them can be present with a safe and effective level, preferably from about 0.01% to about 100%, more preferably from about 0.1% to about 30% and even more preferably from about 0.5% to about 25% by weight of the composition. These materials include, but are not limited to, guanidine; urea; giolic acid and glycolate salts; lactic acid and lactate salts; aloe vera in any of its various forms (eg aloe vera gel); polyhydroxy compounds such as sorbitol, mannitol, glycerol, hexanetriol, butanetriol, propylene glycol, butylene glycol, hexylene glycol and the like; polyethylene glycols; sugars (eg melibiose) and starches; sugar and starch derivatives (eg, glucose, fructose, sucrose, etc., alkoxylated); hyaluronic acid; panthenol and panthenol derivatives; lactate monoethanolamine; acetamide monoethanolamine; sucrose polyester; petrolatum; Silicones and silicone elastomers; hydrocarbon oils; fatty alcohols; acids and fatty esters; esters of mono and dibasic carboxylic acids with monohydric and polyhydric alcohols; polyolefins, polyoxyethylenes; polyoxypropylenes; mixtures of polyoxyethylene and polyoxypropylene ethers of fatty alcohols and mixtures thereof. Many conditioning agents are soft, lubricious fatty materials that produce a conditioning material that is soft to the touch. The silicones useful in the present composition include polyalkylsiloxanes with viscosities from about 5 x 10 ~ 7 to about 1 m2 / s (about 0.5 to about 1, 000,000 centistokes) at 25 ° C. Other silicones suitable for use herein are silicone elastomers, including elastomers of crosslinked emulsifier or non-emulsifier siloxane, silicone gums, silicone resins, aminosilicones, cationic silicones, high refraction silicones or mixtures thereof. The cross-linked organopolysiloxane emulsifier elastomers may be selected especially from the crosslinked polymers described in U.S. Pat. num. 5,412,004, 5,837,793 and 5,811, 487. Advantageously, the non-emulsifying elastomers are the cross-linked dimethicone / vinyl dimethicone polymers. Several suppliers distribute this type of cross-linked dimethicone / vinyl dimethicone polymers; others include Dow Coming (DC 9040, DC 9041, DC9045), General Electric (SFE 839), Shin Etsu (KSG-15, 16, 18) and Grant Industries (GRANSIL ™ elastomer line). The cross-linked organopolysiloxane elastomers useful in the present invention and processes for their manufacture are further described in U.S. Pat. num. 4,970,252, 5,760,116, and 5,654,362. Other cross-linked organopolysiloxane elastomers useful in the present invention are described in Japanese Patent Application No. 61-18708, assigned to Pola Kasei Kogyo KK. Preferably, the conditioning agent is selected from the group comprising glycerol, urea, petrolatum, sucrose polyester, silicones, esters and combinations thereof. 14. Vitamins Examples of vitamins include, but are not limited to, water-soluble forms of vitamin B, vitamin B derivatives, vitamin C, vitamin C derivatives, vitamin K, vitamin K derivatives, vitamin D, vitamin D derivatives, vitamin E, vitamin E derivatives, and mixtures thereof. The vitamin compounds can be included as the substantially pure material or as an extract obtained by physical and / or chemical isolation suitable from natural sources (eg plants).

. Particulate Materials Non-limiting examples of particulate materials useful in the present invention include colorless and colorless pigments, interference pigments, inorganic powders, organic powders, compound powders, optical brightener particles, exfoliants, and combinations thereof. These particulates may have platelet, spherical, elongate or needle shapes or Irregular shapes, may or may not be surface coated, may be porous or non-porous, have or do not load, and may be added to the present compositions as a powder or as a predispersion The particulate materials useful herein include, but are not limited to, bismuth, sericite, mica, mica, barium sulfate-treated or other materials, zeolite, kaolin, silica, boron nitride, lauroillisin, nylon, polyethylene, talc, styrene, polypropylene, polystyrene, ethylene / acrylic acid copolymer, sericite, aluminum oxide, silicone resin, barium sulfate, calcium carbonate, cellulose acetate, PTFE, polymethyl methacrylate, starch, modified starches such as starch and aluminum octenyl succinate , silk, glass, fibers, ground seeds, pumice, and mixtures of these. The spherical particle powders that are particularly preferred are those having an average primary particle size of 0.1 to 75 microns, preferably 0.2 to 30 microns. Interference pigments are also useful herein. For the purposes of the present specification, interference pigments are defined as thin platelet-type laminated particles having two or more layers of controlled thickness with different refractive indices that produce a reflected color characteristic of the interference of normally two, but occasionally more , light reflections of different layers, of the platelet type particle. The most common examples of interference pigments are micas stratified with films of approximately 50-300 nm of TiO2, Fe2O3, silica, tin oxide and / or Cr2O3. Almost always those pigments are pearlescent. The pearlescent pigments reflect, refract and transmit light by the transparency of the pigment particles and the great difference in the refractive index of the mica platelets and, for example, the coating of titanium dioxide. Useful interference pigments are distributed on the market by a wide variety of suppliers, for example Roña (Timiron ™ and Dichrona ™), Eckart (eg Prestige and Prestige Silk lines). Particularly preferred interference pigments are those with smaller particle sizes, with an average diameter of the individual particles of less than about 75 microns in the longest direction, preferably with an average diameter of less than about 50 microns. . Other pigments useful in the present invention impart color primarily through the selective absorption of specific wavelengths of visible light and include inorganic pigments, organic pigments and combinations thereof. Examples of useful inorganic pigments include iron oxides, ferric ammonium ferroclanide, manganese violet, ultramarine blue, and chromium oxide. The organic pigments may include natural dyes and monomeric and polymeric synthetic dyes. An example is the phthalocyanine blue and phthalocyanine green pigments. Lacquers are also useful, FD &Primary C or D &C lacquers and mixtures thereof. Soluble or insoluble encapsulated dyes and other colorants are also useful. The inorganic white or colorless pigments useful in the present invention, for example TiO2, ZnO or ZrO2, are available commercially from a number of sources. An example of appropriate particulate material contains the material obtainable from U.S. Cosmetics (series TRONOX Ti02, SAT-T CR837, a rutile T¡O2). Particularly preferred are the titanium dioxide dispersions as described in U.S. Pat. no. 5,997,887. The pigments / powders useful herein may have a surface treatment that increases color stability and / or facilitates formulation. Non-limiting examples of suitable coating materials include silicones, lecithin, amino acids, metal soaps, polyethylene and collagen. These surface treatments may be hydrophobic or hydrophilic, with hydrophobic treatments being preferred. Particularly useful treatments with hydrophobic pigments include polysiloxane treatments such as those disclosed in U.S. Pat. no. 5,143,722. 16. Amino sugars (amino sugars) The amino sugar compounds useful in the present invention are described in PCT publication WO 02/076423 and U.S. Pat. no. 6,159,485. The amino sugars can be of synthetic or natural origin and can be used as compounds or mixtures of compounds (eg extracts from natural sources or mixtures of synthetic materials). Glucosamine is usually found in many seafood and can also be derived from fungi. As used herein, "amino sugar" includes isomers and tautomers thereof and their salts (eg, HCl salt) and is commercially available from Sigma Chemical Co.

Examples of amino sugars which may be useful herein include glucosamine, N-acetylglucosamine, mannosamine, N-acetylmannosamine, galactosamine, N-acetylgalactosamine, their isomers (eg, stereoisomers) and their salts (eg salt). of HCl). In the present it is preferred to use glucosamine, in particular D-glucosamine and N-acetylglucosamine, especially N-acetyl-D-glucosamine. 17. Vitamin B compounds The compositions of the present invention optionally may comprise a safe and effective amount of a vitamin B3 compound. The vitamin B3 compounds are especially useful for regulating skin conditions, as described in the patent of the USA no. 5,939,082. Exemplary derivatives of the aforementioned vitamin B3 compounds include esters of nicotinic acid, including non-vasodilating esters of nicotinic acid (eg tocopheryl nicotinate, myristyl nicotinate). Examples of suitable vitamin B3 compounds are well known in the industry and are commercially available from a number of sources (eg Sigma Chemical Company, ICN Biomedicals, Inc., and Aldrich Chemical Company). 18. Retinoids As used herein, the term "retinoid" includes all synthetic and / or natural analogues of vitamin A or retinol-like compounds that have on the skin the biological activity of vitamin A, as well as isomers and geometric stereoisomers of these compounds. The retinoid is preferably selected from retinol, retinol esters (for example C2-C22 alkyl esters of retinol, including retinyl palmitate, retinyl acetate, retinyl propionate), retinal and / or retinoic acid (including fully trans-retinoic acid). and / or 13-cis-retinoic acid), or mixtures thereof. More preferably the retinoid is another retinoid other than retinoic acid. Preferred retinoids are retinol, retinyl palmitate, retinyl acetate, retinyl propionate, retinal and combinations thereof. Especially preferred is retinyl propionate. 19. Peptides and amino acids The compositions of the present invention may optionally comprise a safe and effective amount of a peptide, including but not limited to, di, tri, tetra, penta and hexapeptides and derivatives thereof to regulate keratinous tissue. The compositions preferably contain from about 1x10"7% to about 20%, more preferably from about 1x10" 6% to about 10% and even more preferably from about 1x10"5% to about 5%, by weight of the composition , of peptide or amino acid.

As used herein, the term "peptide" refers to peptides containing ten amino acids or less and their derivatives, isomers and complexes with other species such as metal ions (eg, copper, zinc, manganese, magnesium, and the like). ). As used herein, the term "peptide" refers to both natural and artificial peptides. Also present in the present are natural compositions containing peptides and which are commercially available. The most preferred peptides are the dipeptide carnosine (beta-ala-his), the tripeptide gly-his-lys, the pentapeptide lys-thr-thr-lys-ser, the lipophilic peptide derivatives, and the metal complexes of the previous ones, p. ex. tripeptide copper complex his-gly-gly (also known as lamina). A preferred composition comprising commercially available tripeptide derivative is Biopeptide CL®, which contains 100 ppm of palmitoyl-gly-his-lys and is commercially available from Sederma. A preferred composition comprising commercially preferred pentapeptide derivative is Matrixyl®, which contains 100 ppm palmitoyl-lys-thr-thr-lys-ser and is commercially available from Sederma. Useful amino acids include, but are not limited to, aspargine, alanine, indole, glutamic acid, tyrosine, tryptamine and their salts and combinations thereof.

. Phytosterols Examples of suitable phytosterols include β-sitosterol, campesterol, brassicasterol, D5-avenasterol, lupenol, β-sspinasterol, stigmasterol, its derivatives, analogs, and combinations thereof. Preferably, the phytosterol is selected from the group comprising β-sitosterol, campesterol, brassicasterol, stigmasterol, its derivatives, and combinations thereof. More preferably, phytosterol is stigmasterol. The phytosterols may be synthetic or of natural origin and may be used as essentially pure compounds or mixtures of compounds (eg, extracts from natural sources). Phytosterols are generally found in the unsaponifiable portion of vegetable oils and fats and are available as free sterols, acetylated derivatives, sterol esters, ethoxylated or glycosidic derivatives. More preferably, phytosterols are free sterols. As used herein, "phytosterol" includes the isomers and tautomers thereof and is commercially available from Aldrich Chemical Company, Sigma Chemical Company, and Cognis. 21. Hexamidines The compositions of the present invention may optionally comprise a safe and effective amount of hexamidine compounds, their salts and derivatives for regulating the keratinous tissue. As used herein, the hexamidine derivatives include any of the isomers and tautomers of the hexamidine compounds including, but not limited to, the organic acids and mineral acids, for example sulfonic acid, carboxylic acid, etc. Preferably, the hexamidine compounds include hexamidine diisethionate, commercially available as Eleastab® HP100 from Laboratoires Serobiologiques. 22. Dialkanoylhydroxyproline Compounds The compositions of the present invention may optionally comprise a safe and effective amount of one or more dialkanoyl hydroxyproline compounds and their salts and derivatives for regulating keratinous tissue. Suitable derivatives include, but are not limited to, esters, for example fatty esters, among which are included, but not limited to, tripalmitoylhydroxyproline and dipalmitylacetylhydroxyproline. A particularly useful compound is dipalmitoylhydroxyproline. As used herein, the term "dipalmitoylhydroxyproline" includes any of its isomers and tautomers and is commercially available under the trade name Sepilift DPHP® by Seppic, Inc. Dipalmitoylhydroxyproline is also disclosed in the PCT publication document. Publication WO 93/23028. Preferably, dipalmitoylhydroxyproline is the triethanolamine salt of dipalmitoylhydroxyproline. 23. Salicylic Acid Compounds The topical compositions of the present invention may optionally comprise a safe and effective amount of a salicylic acid compound, its esters, its salts, or combinations thereof to regulate the keratinous tissue. 24. N-Acylamino Acid Compounds The topical compositions of the present invention may optionally comprise a safe and effective amount of one or more N-acylamino acid compounds. The amino acid may be one of any of the amino acids known in the industry. Preferably, the N-acylamino acid compound is selected from the group comprising N-acyl phenylalanine, N-acyl tyrosine, its isomers, its salts, and derivatives thereof. The amino acid may be the D or L isomer or a mixture of these. N-undecylenyl-L-phenylalanine is particularly useful as a topical cosmetic agent for matching skin tone. As used herein, N-undecylenyl-L-phenylalanine is commercially available under the tradename Sepiwhite® from SEPPIC.

. Dehydroacetic acid (DHA) The composition of this invention may optionally comprise a safe and effective amount of dehydroacetic acid or pharmaceutically acceptable salts, derivatives or tautomers thereof to regulate the keratinous tissue. The technical name of the dehydroacetic acid is 3-acetyl-6-methyl-2H-pyran-2,4 (3H) -dione. The compound is commercially available from UniversalPreserv-A-Chem, Inc. as Unisept DHA. Pharmaceutically acceptable salts include the alkali metal salts such as sodium and potassium; alkaline earth metal salts such as calcium and magnesium; non-toxic heavy metal salts; ammonium salts; and trialkylammonium salts such as trimethylammonium and triethylammonium. The sodium, potassium and ammonium salts of dehydroacetic acid are preferred. Particularly preferred is sodium dehydroacetate, which can be purchased from Tri-K, such as Tristat SDHA. The dehydroacetic acid derivatives include, but are not limited to, any compound wherein the CH3 groups are replaced singly or in combination by amides, esters, amino groups, alkyls and alcohol esters. The tautomers of dehydroacetic acid are the isomers of dehydroacetic acid which interconvert with great ease so that they generally exist in equilibrium. Therefore, the tautomers of dehydroacetic acid can be described as having the chemical formula C8H8O4 and generally having the above structure. 26. Firming agents for the skin: The firming agents for the skin are materials that immediately after their application make the skin feel tense and reaffirmed. In addition, when these materials produce the effect of tightening the skin, they can also produce the effect of visibly softening the skin, reducing the appearance of the skin texture, fine lines, and wrinkles. Non-limiting examples of skin firming agents useful in the present invention include various natural and synthetic polymers such as those described in U.S. Pat. no. 6,284,233, included herein as a reference. For example, protein extracts from wheat and peas, or egg albumin are effective firming agents for the skin. Other materials such as the silicates described in EP 1008340, included herein as a reference, are also suitable for use in the compositions of the present invention. 27. Anti-dandruff active ingredients The particulate crystalline agents dispersed and suspended throughout the topical composition can provide anti-dandruff activity during the shampooing process. The antidandruff assets used for this purpose include the polyvalent metal salts of pyrithione, salicylic acid, coal tar, wood tar, sulfur, whitfield ointment, castellani paint, aluminum chloride, gentian violet, octopirox (piroctone olamine), cyclopirox olamine, undecylenic acid and its metal salts, potassium permanganate, selenium sulfide, sodium thiosulfate, propylene glycol, bitter orange oil, urea preparations, griseofulvin, 8-hydroxyquinoline cycloquinol, thiobendazole, thiocarbamates, haloprogin, polyenes, hydroxypyridone, morpholine , benzylamine, allylamines (comol erbinafina), tea plant oil, melaleuca extracts (tea plant), charcoal, clove leaf oil, cilantro, palmarosa, berberine, red thyme, climbazole, cinnamon oil, cinnamic aldehyde , citronellic acid, hinokitiol, ichthyol pale, Sensiva SC-50, Elestab HP-100, azelaic acid, lithicase, iodopropynyl butylcarbamate (IPBC), iso thiazolinones such as octylisothiazolinone and azoles, and combinations thereof.

Other ingredients The compositions of the present invention may contain a wide variety of ingredients that are used in conventional product types as long as they do not unacceptably alter the benefits of the invention. Furthermore, when incorporated into the composition, these ingredients must be suitable for use in contact with the keratinous tissue of mammals without producing toxicity, incompatibility, instability, allergic reaction and the like, within the scope of professional medical opinion. The CTFA Cosmetic Ingredient Handbook, second edition (1992) describes a wide variety of non-limiting pharmaceutical and cosmetic ingredients commonly used for the care of keratinous tissue and suitable for use in the compositions herein. invention. Examples of these classes of ingredients and similar classes include: abrasives, absorbers, aesthetic components such as fragrances, pigments, dyes / colorants, essential oils, skin perception agents, astringents, etc. (eg clove oil, menthol, camphor, eucalyptus oil, eugenol, menthyl lactate, witch hazel distillate from Virginia), anti-acne agents, anti-caking agents, anti-foam agents, antimicrobial agents (eg iodopropynyl butylcarbamate) , antioxidants, binders, biological additives, buffering agents, bulking agents, chelating agents, chemical additives, dyes, cosmetic astringents, cosmetic biocides, denaturants, astringents, emollients, external analgesics, materials or film formers, p. ex. polymers, to facilitate the properties of film formation and substantivity of the composition (eg copolymer of eicosene and vinylpyrrolidone), cationic polymers (for example, quaternary ammonium fractions or protonated cationic amine fractions), nonionic polymers, humectants, opacifiers, pH adjusters, propellants, sequestering agents, bleaching agents and skin brighteners, hair conditioning and hair conditioning agents. the skin, sedative and / or curative agents of the skin and derivatives, agents for the treatment of hair and skin, surfactants, thickeners and vitamins, and derivatives thereof. Other examples of suitable emulsifiers and surfactants are presented, for example, in U.S. Pat. num. 3,755,560 and 4,421, 769 and in McCutcheon's Detergents and Emulsifiers, American edition, pages 317-324 (1986). However, it should be mentioned that many materials can provide more than one benefit or act through more than one mode of action. Therefore, the classifications herein are made for the sake of convenience and their intention is not to limit the asset to that particular application or applications listed.Forms of composition The physical form of topical compositions is not a critical factor. The topical compositions of the present invention may be presented in any manner known in the industry, including, but not limited to, solutions, suspensions, dispersions, emulsions, and combinations thereof. For example, emulsified carriers that include, but are not limited to, oil-in-water, water-in-oil, water-in-oil-in-water and oil-in-water-in-oil emulsions are useful herein. As the skilled artisan will understand, in emulsified systems, a given component will be distributed mainly in the aqueous phase or in the oil phase, depending on the solubility / dispersibility in water of the component in the composition. Preferred emulsions are oil-in-water emulsions and water-in-oil emulsions, especially when the entire oil phase or a portion thereof is a silicone or a mixture of silicones. Water-in-oil emulsions can prolong the moderate heat of the composition that is perceived when the composition is applied to the keratinous tissue. Without theoretical limitations of any kind, it is considered that since the water is in the discontinuous phase of the emulsion, it will evaporate more slowly, and consequently the cooling rate of the film of the product on the surface will be lower. This is because evaporation is a cooling process. In one embodiment, the composition is a water-in-oil emulsion in which the majority of the oil is silicone. This type of composition is often called water emulsion in silicone. Non-limiting examples of emulsifiers useful in the emulsions of this invention are mentioned in McCutcheon's, Detergents and Emulsifiers, North American edition (1986), published by Allured Publishing Corporation; and in U.S. Pat. num. 5,011,681, 4,421,769 and 3,755,560. Illustrative carriers and other ingredients that are suitable for use herein are described, for example, in the US Pat. no. 6,060,547. The perceived moderate heat can also last longer if one or more waxy materials having melting points of about 30 ° C to about 80 ° C are included. These compositions contain more than about 1%, more preferably more than about 2% and even more preferably more than about 2.5% by weight of the composition of one of those waxy materials or of a combination thereof. Without theoretical limitations of any kind, these waxy materials melt on heating the composition in the bag, and when those waxy molten materials are applied to the keratinous tissue they crystallize again releasing heat and consequently reducing the rate of cooling of the product on the surface. As will be understood by an experienced technician, the topical compositions of the present invention may exhibit a wide variety of viscosities, depending on the type and level of the structuring or thickening agent or agents included in the formulation. In particular, the compositions may vary from thin and flowable (liquids, milks, lotions, serums, non-thick gels) to thicker products (creams, thicker gels, pastes, ointments), even to semi-solid and solid products ( powders, bars).

Viscosity, measured with commercially available viscometers / rheometers (for example, the viscometers of the Brookfield DV-II and DV-III series models from Brookfield Engineering Laboratories, Inc) is a known way to characterize the thickening of a composition . In a preferred embodiment of the present invention, the viscosity of the topical composition ranges from 10 Pa.s to 500 Pa.s (10,000 cps to 500,000 cps) when measured at the temperature predicted for the topical composition. In another preferred embodiment of the invention, the viscosity of the topical composition at the expected temperature is at least 50% of the viscosity of the topical composition at 22 ° C and still more preferably at least 80%. In this way, the composition does not become excessively fluid or difficult to handle during application, and its rheological properties will continue to be relatively constant, regardless of whether a person uses the product at room temperature or any temperature lower than the predetermined temperature in the system. of heating. The topical compositions herein may be cleansers that include, but are not limited to, shampoos, body wash, liquid soaps in general, and scrubs. Topical compositions can also be humectants; anti-aging products; Sunscreens; pharmaceutical products; dermatological products; hair colorants; hair conditioners; antiperspirants; deodorants; toothpaste; cosmetics that include, but are not limited to, foundation for makeup, blush mask, lipstick and shine for nails; depilatories; patches, masks; and products for massages. The topical composition may optionally comprise materials that change color or level of opacity after moderately heating the composition. This would produce a visual signal based on the topical composition.

Preparation of the Composition The compositions of the present invention are generally prepared using conventional methods such as those known in the industry for the preparation of topical compositions. These methods usually involve mixing the ingredients in one or more steps to a relatively uniform state, with or without heating, cooling, vacuum application, and the like. Preferably, the compositions are prepared to optimize stability (physical stability, chemical stability, photostability) or the supply of the active materials. This optimization may include appropriate pH (eg less than 7), exclusion of materials that can be complexed with the active agent, which would negatively impact stability or dispatch (eg exclusion of contaminating iron), use of techniques to prevent the formation of complexes (eg suitable dispersing agents or double-compartment packaging), use of appropriate photostability techniques (eg incorporation of sunscreen / sunscreen products, use of opaque packaging), etc.

EXAMPLES The following are non-limiting examples of the compositions of the present invention. The examples are provided solely for the purpose of illustration and will not be considered as restrictions of the present invention since, as will be recognized by a person of ordinary skill in the industry, it is possible to effect many variations without departing from the spirit and scope of the invention. All concentrations in the examples are listed in percent by weight unless otherwise specified and minor materials such as diluents, fillers, and so on can be excluded. Therefore, the formulations listed comprise the listed components and any minor materials associated with these components. For a person of ordinary skill in the industry it is evident that the selection of these minor components will vary depending on the physical and chemical characteristics of the particular ingredients selected to prepare the present invention as described herein.

EXAMPLE 1-3 Seeds / lotions of silicone emulsion in water 1 A blend of silicone elastomer from Dow Coming Corporation 2 A blend of silicone elastomer from ShinEtsu 3 A blend of silicone rubber from Dow Coming Corporation 4 A spherical polyethylene powder from Equistar 5 A green interference pigment in mica layers / titanium dioxide / tin oxide from Eckart 6 A thickening agent of sodium acrylate copolymer / acryloyldimethyl taurate from Seppic 7 A crosslinked polymer from C10-30 acrylate / alkylacrylate from Noveon 8 A copolymer based on polyacrylamide (with a certain functionality of sulfonic acid) of Seppic 9 A mixture of liquid preservative distributed by Lonza In a suitable container combine the Carbopol and the ingredients of the aqueous phase and mix until a homogeneous mixture is obtained. In another suitable vessel, the ingredients of the oil phase are combined and mixed until a homogeneous mixture is obtained. The oil phase is added to the aqueous phase and the resulting emulsion is milled (eg with a stator-rotor mill). The different thickener is added to the Carbopol and the remaining remaining ingredients in the emulsion and mixed until a homogeneous mixture is obtained. Sacks suitable for use with the receptacle are filled.

EXAMPLES 4-8 Oil lotions / creams in water 1 Distributed by Kobo 2 products Palmitoyl-lysine-threonine-threonine-lysine-serine, distributed by Sederma 3 Violet interference pigment, from mica coated with titanium dioxide, from Eckart 4 Red interference pigment, from mica coated with titanium dioxide and silica, from Roña In a suitable vessel, the ingredients of the aqueous phase are combined and heated to 75 ° C. In another suitable vessel, the ingredients of the oil phase are combined and heated to 75 ° C. The oil phase is added to the aqueous phase and the resulting emulsion is milled (eg with a stator-rotor mill). The thickener is added to the emulsion and the emulsion is cooled to 45 ° C while stirring. At 45 ° C, the rest of the ingredients are added. The product is cooled and stirred at 30 ° C. Sacks suitable for use with the receptacle are filled.

EXAMPLES 9-13 Sera / lotions of silicone in water: 1 GL 75CAP-MP, aqueous dispersion of 75% titanium dioxide, Kobo 2 Palmitoyl-lysine-threonine-threonine-lysine-serine, distributed by Sederma 3 Dispersion of silicone elastomer, from Dow Corning Corp 4 Silicone elastomer dispersion, by Shin Etsu, 5 Eckart titanium dioxide red, mica interference interference pigment In a suitable container, the ingredients of the aqueous phase are combined and mixed until a homogeneous mixture is obtained. In another suitable container, the ingredients of the oil / silicone phase are combined and mixed until a homogeneous mixture is obtained. Separately, the premix of dipalmitoylhydroxyproline and / or that of undecylenyl phenylalanine is prepared by combining the ingredients of the premix in a suitable vessel, heating them to about 70 ° C with stirring and cooling them to room temperature while stirring. Half of the thickener is added and then the oil / silicone phase to the aqueous phase and the resulting mixture is milled (eg with a stator-rotor mill). If appropriate, add the rest of the thickener, the premix of dipalmitoylhydroxyproline and / or undecylenyl phenylalanine in the emulsion and then the rest of the ingredients with agitation.

Stir until the composition is homogeneous. Sacks suitable for use with the receptacle are filled.

EXAMPLES 14-19 Creams / lotions hydrating water in silicone: 1 Palmitoyl-lysine-threonine-threonine-lysine-serine, distributed by Sederma 2 KSG-21 is an emulsifying silicone elastomer, distributed by Shin Etsu 3 Dispersion of silicone elastomer, from Dow Corning Corp 4 Abil EM-97 distributed by Goldschmidt Chemical Corporation In a suitable container, the components of Phase A are mixed using a suitable mixer (for example the Tekmar equipment model RW20DZM) until all the components are dissolved. The components of Phase B are then mixed in a suitable container and milled using a suitable mill (for example Tekmar RW-20) for about 5 minutes. The components of Phase C are added to the mixture of Phase B and mixing is maintained. Next, the components of Phase D are added to the mixture of Phases B and C and (a combination resulting from the components of Phases B, C and D is mixed using a suitable mixer (for example Tekmar RW-20) for approximately 1 hour, if appropriate, prepare the premix of undecylenyl phenylalanine and / or phase E combining all the ingredients, heating them to 70 ° C with agitation and cooling them with agitation until reaching room temperature again. Add the premix of undecylenyl phenylalanine and / or Phase E to Phase A while stirring.After mixing, phase A is slowly added to the mixture of Phases B, C and D. The resulting mixture is constantly mixed until the product is homogeneous. The resulting product is then milled for approximately 5 minutes using a suitable mill (for example Tekmar T-25). Sacks suitable for use with the receptacle are filled.

EXAMPLES 20-23 Aqueous solid formulations All ingredients are combined in a container of the appropriate size, heated to 85 ° C and cooled. Sacs suitable for use with the receptacle are filled at about 65-70 ° C.

EXAMPLES 24-27 Anhydrous Solid Formulations All the ingredients are added in a container of the appropriate size, heated to 75 ° C and then cooled with stirring until the mixture reaches a temperature of about 45-50 ° C. Sacks suitable for use with the receptacle are filled.

EXAMPLES 28-29 Aqueous gel formulations In a container of the appropriate size all the ingredients are combined and mixed until a homogeneous mixture is obtained. Sacks suitable for use with the receptacle are filled.

EXAMPLE 30 Formulation of shampoo In a container of the appropriate size all the ingredients are combined and mixed until a homogeneous mixture is obtained. Sacks suitable for use with the receptacle are filled.

EXAMPLE 31 Facial cleanser Oxidized polyethylene particles having an average particle size of 25 microns in diameter, available as Acumist A-25 from Allied Signal Corp. Oxidized polyethylene particles having an average particle size of 45 microns in diameter, available as Acumist A- 45 from Allied Signal Corp.

In a suitable vessel water, glycerin and disodium EDTA are mixed and heated to 75-80 ° C with stirring. In another vessel, PPG-14 butyl ether and salicylic acid are heated to 75-80 ° C with stirring to form an oil phase. In this oily phase, the stearyl alcohol, the cetyl alcohol and the behenyl alcohol are added with stirring while heating. The distearyl dimethyl ammonium chloride, steareth-2 and steareth-21 are then added to the oil phase while heating and stirring. This oil phase is emulsified in the water-containing mixture using a homogenizer mill. The resulting emulsion is cooled with stirring at 45 ° C and the urea and the fragrance are added. The emulsion is cooled to room temperature with stirring. The sodium alkyl sulphate and the cetyl betaine are then mixed, followed by the polyethylene particles.

EXAMPLE 31 Hair coloring EXAMPLE 32 1 Available as polymer JR 400 2 Na Lauriminodipropionate available as Mirataine H2CHA 3 Cocoanfocarboxiglycinate (and) Na (y) hexylene glycol lauryl sulfate available as Miranol 2MCA MOD 4 Available as Crothix 5 Available as Glucamate DOE120 The water is heated to 65 ° C. The polyquatemium-10 is added to the water to form Phase A. In this phase, the ingredients of Phase B are added in sequence. Separately, the components of Phase C are heated to 65 ° C. Phase C is combined with this mixture. Phases A, B and C are cooled to 40 ° C. In this mixture Phases D and E are added to form the resulting cosmetic composition.

EXAMPLES 33-34 Liquid make-up compositions 1 - Shin-Etsu - KP-545 - 3M - SA-70 - ISP - Ceraphyl 55 4. DeGussa Goldsmith - Abil WE-09 5- Rhodasurf L-7/90 by Rhodia 6- Dry Fio Elite BN from National Starch 7- Tospearl 145A from GE 8- BPD-500T from Kobo 9- Dow Corning - DC 9506 Powder 10. GE - Velvesil -1111-19-372 11. Kobo silica shells Deionized water and Silica Shells from Phase D are combined and mixed with the propeller mixer or disperser until a homogeneous mixture is obtained. Add the ingredients of Phase D that were missing and continue mixing with the propeller mixer or with the disperser. The ingredients of Phase A are combined in a container with a jacket and the mixing begins in a stator-rotor mill. Cold water is circulated through the container with a jacket. The ingredients of phase B are mixed for ten minutes. The mixed phase B is added to the ingredients of phase A. The ingredients of phase C are added to the AB phase. Shear stress is applied to the ABC phase until it is completely deagglomerated and the pigments have been reduced to their primary particle size. Phase D is emulsified in the ABC phase with a moderate shear stress. The ABCD phase is mixed by means of a wall-type mixing until a uniform mixture is obtained. Sacks suitable for use with the receptacle are filled.

EXAMPLE 35 Disposable cloth An emulsion (composition A) containing approximately 96.4% water, 2% silicone oil, 0.15% polymeric carboxylic acid emulsifier, 1% water soluble alkylene polyol, 0.1% chelating agent, 0.2% agent is prepared antimicrobial, 0.15% organic pH adjusting agent and fragrance as follows. A standard size cylindrical drum is used to prepare the emulsion, 208 I (55 gallons), equipped with a single axle that has two impeller blades driven by a 178 rad / s (1750 rpm) engine. The shaft extends for almost the entire depth of the drum (approximately 1.2 m (4 ft)) and has a first pallet located near the bottom of the drum and a second pallet about 1 ft. Above the first. The first blade has a diameter similar to the diameter of the drum (approximately 0.6 m (2 feet)) and the second blade has a diameter of approximately 0.3 m (1 foot). The drum is loaded with 151 to 181.7 I (40 to 48 gallons) of tap water. To start shaking the water, the engine must be at its maximum speed. Stirring continues at this speed throughout the process. 236 g (0.52 pounds) of Pemulen® TR-2 are slowly added so that mixing of the emulsifier is sufficient to disperse the emulsifier or to prevent lumps from forming. Then the following components are added in the order mentioned: 158.7 g (0.35 pounds) of tetrasodium EDTA; 1.5 kg (3.49 pounds) of propylene glycol; 3.2 kg (6.97 pounds) of dimethicone (Dow Corning 200 Fluid, 0.00035 m2 / s (350 cs)); 317.5 g (0.70 pounds) of Glydant Plus®; 4.5 g (0.01 pounds) of fragrance. Each of the above ingredients is mixed in the water separately until they are well mixed in the resulting mixture, typically stirred for about 1 minute before adding the individual ingredients and for approximately 5-10 minutes once all the ingredients are added. They are in the container. Then 235.9 g (0.52 pounds) of triethanolamine are added and stirring is continued for approximately 15-20 minutes or until a homogeneous mixture is achieved. A cloth composed of a 100% NSK fiber two-sheet cellulose substrate having a basis weight of 11.3 kg (26 pounds) per sheet and a gauge of 508 μm (20 mils) per sheet is laminated, under pressure with a adhesive, and rolled into a continuous weft roll. Suitable adhesives have sufficient wet strength so that the sheets remain substantially bonded during use. The weft roll is cut lengthwise to obtain the desired final width for the cloth (eg 29.2 cm (11.5") in the unfolded configuration), and is folded into z in such a way that the edges in the direction of machine overlap approximately 1.27 cm (0.5"). The obtained long and folded cut wefts are impregnated with the composition A by passing the individual wefts on top of individual distributors having orifices through which the composition is pumped under pressure on the moving web. The composition is pumped to provide a load of approximately 15.5 grams of composition per finished cloth. After impregnation, the wefts are cut to the desired length for the finished cloth (eg, approximately 21.6 cm (8.5").) The cloths are placed in sacks suitable for use with the receptacle herein.

Sacks The sacks used herein comprise a plurality of surfaces defining at least one chamber for containing the composition. Therefore, although single-chamber sacks are often used, sacks with a plurality of chambers or with multiple chambers can also be used in the present invention. Typically, one or more of one of the surfaces of the bag has a low thermal resistance. Since more than one wall of the receptacle can have an associated heating system, the sacks having several surfaces with different thermal resistance will be heated quickly and uniformly. The bag can be manufactured with a wide variety of materials alone or in combination. The surfaces of the bag can be thick or thin. The materials can also be chosen in such a way as to provide the desired thermal resistance, light resistance, oxygen barrier and moisture barrier. In preferred embodiments, the entire bag or a portion thereof comprises films formed from plastics, polymers, and aluminum foil in a single layer, in multiple, mixed or metallized layers and combinations thereof. Examples of these materials are polyolefins, polyesters, nylon, polypropylene, polyethylene, ethylene vinyl acetate, metallized PET (polyethylene terephthalate), aluminum foil, EVOH (ethylene-vinyl alcohol copolymer), PVDC (polyvinylidene chloride) ), etc. Other materials that can be used include, among others, cardboard. An example of a material used for the bag is a coextruded polypropylene film on the outside and a polyethylene / ethylene vinyl acetate blend on the inside as the sealing layer. Similar sacks can be obtained from Flexpaq, South Plainfield, NJ. Various means for opening a sack are known in the industry and these means can be used with the sacks described herein. These include, but are not limited to, detachment by means of a tongue, cutting along a line of brittleness, pressure, etc. Sacks that can be resealed are also contemplated. In some embodiments, the bag may be designed to burst or break to release the topical composition contained therein by applying a comparatively mild force when the consumer so wishes. This can be done when the bag is a closed bag with permanent hermetic closures and "fragile", that is to say breakable, hermetic closures. When tightening the bag, the fragile seal will yield or fail first since it has a lower take-off resistance than the permanent seal. By adding stress concentrators in the geometry of the seal that will locate the forces at a particular location, the location of the break can be optimized. For example, by pressurizing a bag-shaped bag that has a V-notch seal, the forces will first be located at the apex of the V, causing that region to break first. In addition, other angles and geometries of the seal can be used to adapt the delivery forces of the topical composition from a bag in the case of specific applications. Other considerations about breakable seals, including their manufacture, are mentioned in U.S. Pat. no. 6,508,602. The embodiment of the pouch illustrated in Figure 5a is a thermoformed blister 500 with a tab that breaks to open 510 and allows the composition to be dispensed by breaking the tab 510 along a line of brittleness 540. This type of pouch is manufactured by thermoforming means from a sheet of material, of a front surface 550 of the bag so as to form a small chamber 520 for containing the topical composition. Then, the chamber 520 is filled and another layer of material forming the back surface 530 is hermetically sealed around the perimeter 560 of the chamber to contain the topical composition until ready for use. Figures 5b to 5d illustrate other views of this embodiment. Figure 5e illustrates a cross-sectional view of the sack of Figure 5a taken along the line A-A in which the topical composition 560 is observed within the chamber 520. Other means of making sacks are known in the industry., bags, containers, blister packs, cells, thermoformed cups and other forms of bags to contain a liquid, gel or solid and can be used to manufacture receptacles suitable for this application. A sack may comprise a plurality of compartments.

These "double" or multiple compartment sacks are useful in several applications, especially when two incompatible products will be applied. Figure 6a depicts another embodiment of the sac 600 functionally similar to that of Figure 5a, but includes a plurality of chambers 620 and 621 separated by a seal622. The figure. 6b is a cross-sectional view of the bag illustrated in Figure 6a taken along line A-A to contain topical compositions 670 and 671 and including respective voids 680 and 681, illustrated in Figure 6b. The respective chambers 620 and 621 may include identical, similar or different topical compositions. The seal 622 separating the chambers 620 and 621 and the circumferential closure 660 can be designed to break in sequence or simultaneously depending on the force of takeoff and the way in which the user applies pressure or tightens the container. Sacks having multiple chambers, such as the one illustrated in Figure 6a, may also be designed to mix incompatible topical compositions. In this way, the bag could provide multiple benefits such as cleaning from one chamber and hydration from the other. The chamber containing the cleaner would be dispensed first to clean the hair, nails, face, hands or body and the second chamber containing the moisturizer would then be dispensed to deeply hydrate the hair, nails, face, hands or body. Alternatively, if two topical compositions are dispensed from the bag that act upon mixing during shipping, a reaction such as foaming or additional self-heating could be achieved. For example, a double-compartment bag should have a chamber with an aqueous cleanser such that upon contact, the two components produce a topical composition that generates foam. As an alternative to a bag that contains incompatible products, the bags can also contain a unique product whose components should be mixed just before application due to the instability of the components when mixed. In those examples, these components may be separated into a plurality of sac chambers. The user can break the breakable seals separating these chambers such that the composition is mixed just prior to application. Figure 7a illustrates a modality of the pouch 700 with two compartments 723 and 724, wherein the sealing 725 that divides 723 of 724 is in the middle vertical line. The bag has a tab that is broken open 710, removed by the line of brittleness 740. The topical compositions contained in the compartments 723 and 724 can be mixed once they are out of the bag. Figures 7b and 7c also illustrate the pouch 700. Although the pouch described herein may contain a sufficient amount of the composition for multiple uses, in one embodiment, the pouch is designed for a single use, i.e., a unit dose. Since the unit dose can be applied to the user's total keratinous surface, for example, on the entire skin, hair or nail surface, or it can be a specific application, a unit dose can vary from 0.1 gram to 30 grams . The perimeter or the hermetic closures of the bag can be made in such a way as to generate a dispatch opening that allows to control with greater accuracy the topical composition when dispensing it. In this way, the accuracy of the composition is improved, but it can also be used so that it is necessary to apply reasonable force to dispatch the product. By reducing the width of the outlet opening, the product can be prevented from leaking from the receptacle, unless the user applies considerable force in the receptacle to dispatch the product at the desired time. Although in some variants you can use a bag that opens before heating it, the bag will usually remain closed during heating, since topical compositions or active ingredients of those compositions can degrade when exposed to air, oxygen, light and / or microbes. The advantages of the embodiments of the present invention in which a bag is used include minimization of the exposure of the composition to these degrading conditions, before heating and due to the characteristic of the bags having a limited volume after heating and the application in the keratinous tissue. This promotes the efficacy of the composition and / or its active ingredients that may have been avoided in the past due to their susceptibility to degradation. Another benefit that heating the closed bag provides is that the contents do not spill into the interior of the device. In this way the clutter is reduced and the possibility of the liquid product entering the device, typically electric, and causing some malfunction in its operation is minimized. Avoiding contact of the product with atmospheric gases also improves the stability of the topical composition. Therefore, the bag can be manufactured in such a way that it has a minimum empty space or without an empty space, and / or with a non-oxidizing gas other than air, such as nitrogen. In some modalities, the sac can be flexible and in others it is rigid. When the flexible bags are placed in a receptacle of the appropriate shape they deform around a heat sink in the receptacle so that the heat is transferred to the bag, and therefore to its contents, with maximum efficiency. The contents of the flexible bags can also be dispensed in the hand when tightening the bag. A rigid blister with a flexible back film cover can provide a disc from which the product can be removed with the fingers after removing the back cover. It is essential that heat is transferred to the sack and its contents and from these during heating and use as this determines how quickly the sack and its contents are moderately heated and cooled. Since the heat transfer to the topical composition that is inside a sack is a function of the thermal resistance of the material comprising the sack, to heat the composition of the sack in a given time and to keep it at a temperature predicted in the receptacle for its immediate application in the keratinous tissue, the materials of the sack surfaces must be carefully selected. For example, increasing the thickness of the surface of the bag will increase the thermal resistance of that surface. Higher thermal resistance reduces the rate of heat transfer to the composition through the surface. Therefore, the time necessary to moderately heat the composition to a specific temperature in a sack having thicker surfaces will be greater, but the moderate heat of the composition will be maintained for a longer time. The thermal conductivity of a material also alters the thermal resistance. Materials that have a higher thermal conductivity can be used to reduce the thermal resistance of the surfaces. Materials that have a lower thermal conductivity can be used to make surfaces with higher thermal resistance. The heat transfer area also affects the thermal resistance of the bag surface. The larger the area, the lower the thermal resistance. The larger heat transfer areas reduce the heating and cooling time of the bags. Also included are combinations of materials included in the same bag. For example, a surface of the bag may have higher thermal resistance. In this way the loss of heat towards the user's fingers while that user holds the bag would be less. This surface would not feel so hot to the touch. If you select a material with higher thermal conductivity, such as an aluminum foil instead of a plastic, the thermal resistance is reduced. A bag made with an aluminum foil will heat up faster, but it will also cool quickly. Another way to reduce thermal resistance is to increase the heat transfer area. Thus, material combinations would provide thermally insulated surfaces, while surfaces of lower thermal resistance would allow the surface to warm moderately faster. The bag may comprise at least one surface coated or impregnated with a volatile material. When heating the sack, the volatile material, such as perfume, aromatizes the surrounding air. For the surfaces of the bag optionally materials that change color or level of opacity can be used when the topical composition is moderately heated. This would produce a visual signal based on the surfaces of the bag. One embodiment of the bag comprises a solid that includes powder, globules, minerals, etc. In another embodiment, one of the surfaces of the bag may comprise an applicator for the topical composition. For example, the surface to be used as an applicator may comprise a portion of material similar to a sponge. This sponge-like portion will ensure that the topical composition is uniformly applied to the keratinous tissue of the wearer. Alternatively, the applicator may be in the form of a brush, a dropper or a syringe.

In another embodiment, the bag comprises topical compositions combined with a substrate for cleaning, treatment or other uses. In a preferred embodiment, the composition is previously combined with the substrate or wipe to form a cloth product, e.g. ex. disposable cloths, to be used later for that purpose. In a preferred embodiment, the cloth product includes a nonwoven fabric substrate impregnated with a topical composition within the bag. The bag may be presented in various forms including, but not limited to, small bags, containers, cells, blister packs, thermoformed cups, capsules, ampoules, boxes, cones, balloon shapes, bellows shapes, small flexible or rigid bags with Multiple sides, syringes, drippers or vials. The bag can be flat, rounded or combinations of these.

Receptacle The receptacle comprising a heating system comprises a cavity into which the bag is placed in releasable form. The heating system used herein comprises a heating element associated with a wall of the cavity. Alternatively, the heating element may be associated with a plurality of walls of the cavity. For example, in embodiments of the invention in which multiple bags are heated simultaneously, the heating element may extend from the wall of the cavity adjacent to the energy source, laterally along the walls of the cavity or completely around the wall. the inner surface of the receptacle. In an alternative embodiment, the heating element and / or the heat sink can be located in the center of the cavity in such a way that a sack can be placed on each side and these are heated simultaneously. In one embodiment, the heating system is activated by means of a manual switch. In another embodiment, the heating system is activated by placing a bag inside the cavity of the receptacle, and thereby engaging a switch that is in contact with an internal wall of the cavity. The area of the bag that attaches to the switch is referred to as the "point of contact". Figure 8a illustrates an embodiment of bag 800 with point of contact 890 designed to activate the heating system by means of a switch located in the lower part of the cavity in some embodiments of the receptacle. Figure 8b is a side view and Figure 8c is a perspective view of the bag 800, in which the contact point 890 is illustrated. Other optional components that can be used in the heating system described herein include a heat sink in contact with the heating element and temperature sensors, optionally in contact with the heat sink. Optionally, a fuse or thermal switch can be used between the heating element and the power source. The indicators that comprise visual feedback mechanisms, auditory feedback mechanisms, tactile feedback mechanisms, and combinations thereof, can be operatively associated with a temperature sensor, a regulator and combinations of these. To control all the functions of the heating systems, including the indicator, a regulator can be used. The regulator may comprise a microprocessor, microcontroller, timer or sensor and also other elements. In another embodiment, the heating system is activated when a bag having one or more projections is placed on its outer surface. The protrusions come into contact with switches located on the walls of the cavity. The projections can have a "lock function" so that the heating system is not activated accidentally when foreign objects are inserted in the device, preventing these objects from melting and destroying the receptacle. In another embodiment, a sensor located in the wall of the receptacle detects the presence of the bag and activates the heating element. When the bag is removed, the heating element is deactivated and the receptacle stops providing heat. The operation of the sensors can be based on the changes that occur in the resistancecapacitance, inductance, light transmission, force, pressure, voltage, current or other means when the bag is inserted into the device as opposed to the existing ones when the bag is not in the device. For example, a photodiode that receives light from an electroluminescent diode (LED) could be covered by the bag, and thereby changes the output signal of the photodiode. This change in light intensity could be used to control the heater. A bag with the proper properties to change the desired signal for the sensor could provide a locking function. Moderate heating of the topical composition to its intended temperature occurs in about 30 seconds to about 5 minutes, preferably in about 30 seconds to about 2 minutes. The temperature predicted for the composition is from about 30 ° C to about 65 ° C, preferably from about 35 ° C to about 65 ° C, more preferably from about 37 ° C to about 60 ° C and most preferably from about 40 ° C to about 55 ° C. In an alternative embodiment, the heating system maintains the predicted temperature for the composition for a predetermined time. This time is from about 1 minute to 1 hour and preferably from about 3 minutes to about 30 minutes. Optionally a heat sink can be used in contact with the heating element to transfer and distribute the heat generated by that element. A temperature sensor may be in contact with the heat sink, and a regulator may be in contact with the temperature sensor. When the temperature sensor generates a signal indicating that the temperature of the heatsink exceeds its operating temperature for a predetermined period, the regulator can regulate or interrupt the power supply to the heatsink so that it heats up and thereby reduce the temperature of the heatsink. temperature of the composition inside the bag up to the interval of the predicted temperature. This interruption of the power supply to the heating element can act as a thermostat, a safety feature and an energy saving feature. When the bag is heated for a specific period at a specific temperature without removing it, the heat supply is interrupted until the bag is removed and replaced or until the heating element is activated in some other way. On the contrary, when the temperature sensor generates a signal indicating that the temperature of the heat sink is lower than its operating temperature, the regulator can regulate the power supply to the heat sink to increase the heat and consequently an increase occurs. in the temperature of the composition inside the bag up to the interval of the predicted temperature. Preferred heating elements for use in the invention described herein are electric resistance heaters. Examples include cable or sheet of strong alloy, thermal conductive plastics, carbon / silver ink printed on polyester or other flexible materials, flexible heaters, positive temperature coefficient heaters (ceramic stones), thick film heaters, or components electrical that emit heat due to electrical resistance to current flow. The specific types of electrical resistance heaters of the type of resistant alloy cables or sheets that can be selected are: cable elements in metal tubes, embedded cable elements molded in heating units, wire cable heaters, LCD heaters and cable heaters with ceramic fiber insulation. Other types of heaters suitable for use in the invention described herein are: Peltier heaters, microwave emitters, elements that radiate heat, light bulbs and heat lamps. In order to produce the heat necessary to heat the composition moderately, chemical products can also be used which, when combined, produce an exothermic reaction. Examples include heat produced by hydration reactions, anhydrous reactions, heat produced by dissolution and neutralization reactions, oxidation reactions, crystallization reactions, electrochemical heating, material for phase change, condensation, etc. The power supply can come from various sources: AC or DC power, battery, solar energy, combustible gases, chemical reaction or any combination of these. The combustible gases useful in the present invention include those which are known for their use in portable butane devices for curling hair. In another embodiment, the receptacle comprises an indicator; the indicator is operatively associated with the temperature sensor, the regulator or the timer. When the composition reaches the expected temperature or at the end of a predetermined period the indicator generates a signal. The signal may indicate "heating", "hot", "ready", "holding", "on" or "off". The signal that the indicator emits can be a visual signal, an auditory signal or a combination of these. The selection of the material and the thermal resistance of the receptacle also affect its performance. For example, if a heat sink is included its thermal resistance should be low and the stored heat should be minimal when it is desired to heat the bag moderately quickly. The walls of the receptacle cavity should be made of a material with a nominal capacity to withstand the temperatures and voltages that the receptacle might receive. Underwriters' Laboratories Inc. establishes the nominal capacity of these materials. The walls of the receptacle cavity must have the nominal capacity established by UL for these materials and may have a higher thermal resistance to avoid the loss of heat to the surrounding environment. Although heat sinks are commonly used in the receptacles described herein, in some examples they may not be necessary. For example, a flexible film heater made of carbon and silver printed on polyester can quickly and efficiently heat a bag if placed directly in contact with that bag. Those heaters, produced by Conductive Technologies, Inc., York, PA, are used in medical applications to heat intravenous fluids to body temperature. These heating systems are also heaters with a positive temperature coefficient.

Figure 1a illustrates one embodiment of the receptacle 100 described herein. In the receptacle 100 a sac 101 is observed within the cavity 114. In this example, energy is the current commonly supplied in US homes. (110-120 V) conducted through the plug 113. Figure 1b illustrates a right side view of the embodiment of Figure 1a without the bag. Figure 1c is a planar top view of the receptacle of Figure 1a, where the front housing 111, the cavity 114, the plug 113 and the rear housing 115 are observed. Figure 1d is an exploded view of Figure 1a without The bag. The front housing 111 and the rear housing 115 enclose a printed circuit board 116 containing a microcontroller. The microcontroller stores and executes the instructions of the program that handles all the other components. A heating element 117 is operatively associated with the heat sink 118. In this embodiment, when the bag is placed, a switch 119 is pressed and the heating element 117 is activated. The inner plate 110 forms the rear wall of the cavity 114 to contain the coat. A portasachet 121 is located on the front surface of the inner plate 110. The electroluminescent diode (LED) 123 produces a signal indicating whether the receptacle 100 is in the ramp or maintenance mode described below. The element 122 is a silicone rubber insulation that protects the printed circuit board (PCB) from the heating element. Resistance temperature detectors (RTDs) 127 measure the temperature of the heating element or heat sink. A thermal switch (TCO) that is not shown interrupts the flow of current to the heating element in case the temperature measured by the TCO exceeds its nominal operating temperature. In this mode, the TCO used in the device has an operating temperature stipulated by UL of 120 ° C. The element 119 mentioned above is a switch. The switch extends into the interior of the cavity 114 in which the bag is placed. When the bag is placed, the switch 119 is activated and consequently the heating element 117 is activated. The plug 113 connects the heating element 117 to the electric current. Figure 2a illustrates a second embodiment of the receptacle 200 described herein. In this example, the receptacle contains a battery 233 illustrated in Figure 2c. The front housing 211 of the receptacle 200 encloses the front portion of the cavity 214. Figure 2b illustrates a right side view of the embodiment of the Figure 2a where the rear housing 215 of the receptacle 200 is observed. Figure 2c is a cross-sectional view of Figure 2a taken along the line A-A. The front housing 211 and the rear housing 215 enclose the cavity 214 and the heating system (not shown). Figure 2d is a top plan view of the receptacle 200 of Figure 2a.

Figure 2e illustrates the rear housing 215 of the receptacle 200. The element 250 is an opening in the rear housing that allows the receptacle to be hung by a suitable means. Figure 3a illustrates a third embodiment of the receptacle described herein. This receptacle 300 is designed to simultaneously heat two sacks. These sacks may comprise the same or different topical compositions. The elements 314a and 314b are two areas of the pocket of the receptacle into which the bag is placed. Figure 3b is a top plan view that also illustrates the receptacle 300. Figure 4a illustrates another embodiment in which a receptacle 400 is placed for recharging, in a coupling station 431 connected to the electric current by means of a plug 413 Figure 4c is a cross-sectional view of the receptacle with the docking station taken along line AA of Figure 4b which is a top flat view of 400. This cross-section illustrates a battery 433 that can be recharged while it is placed in the docking station 431. This mode allows the use of rechargeable batteries, so that if the batteries are fully charged, the receptacle can be used in remote locations. Figure 4d illustrates a left side view that also shows the receptacle 400. The heating cycle may optionally consist of two distinct modes: a ramp mode, when the sack and its contents are in heating process and a maintenance mode. During maintenance mode, the bag and its contents are kept at a constant temperature. If at any time during the heating cycle the bag is removed from the device, the heater will shut off. With reference to the illustration of Figure 1, during the ramp mode, a temperature detector of the resistor 127 illustrated in Figure 1d measures the temperature of the heater to heat the heat sink seal. The microprocessor of the printed circuit board 116 calculates a ramp index for the heater, such that the bag and its contents reach a temperature of 50 ° C in 3 minutes. At the end of the ramp mode, the maintenance mode begins. During maintenance mode, the heater temperature is set to 60 ° C for 15 minutes. If the bag is not removed after 15 minutes, the heater shuts off. In order for the receptacle to begin to heat up again, the user must remove the bag and place it again. When replacing the bag, the heating cycle will be repeated. Figure 9a is a perspective view of a fifth embodiment of the receptacle 900 having two heating elements and two heat sinks, the front housing 911, the rear housing 915 and the plug 913. Figure 9b is a front flat view of the receptacle 900 illustrating the front housing 911. Figure 9c is a cross-sectional view of the receptacle 900 taken along line BB of Figure 9b. The elements 917a and 917b are heating elements. The elements 991a and 918b are heat sinks for the heating elements adjacent thereto.

Optionally, materials that change color or level of opacity can optionally be used when the topical composition is moderately heated. This would produce a visual signal based on the receptacle.

Method The method for treating keratinous tissue comprises as a first step the heating of a topical composition contained in a sac using a receptacle, as described above. The energy source supplies the heating system with sufficient energy to moderately heat the composition within the bag to a sufficient predicted temperature so that the composition is easy to apply to the keratinous tissue, but is not so fluid as to glide over the surface when it is applied Generally, the temperature is about 30 ° C to 65 ° C. Once the composition is heated moderately, it is removed from the bag and applied to the keratinous tissue. The application of the topical composition may be usual. "Typical topical application" refers to the continuous topical application of the composition for a prolonged period, preferably for a period of at least about one week, more preferably for a period of at least about one month, even more preferably over at least about three months, even more preferably at least about six months, and even more preferably at least about one year. Typically, applications would be approximately once a day; however, the frequency of application may vary from approximately once a week to approximately three or more times a day.

Regimen A regimen for skin care using a receptacle as described above comprises the steps of: selecting a sack between several sacks, placing the sack so that it can be released into the receptacle, and activating the heating system operatively associated with receptacle. The topical composition is then heated moderately in the sack. Once heated moderately, the bag opens and the warm composition is applied to the skin of a user. A typical application program of the topical composition, similar to that described above, can be used in the skin care regimen. All documents cited in the Detailed Description of the invention are incorporated, in the pertinent part, by reference herein; The mention of any document should not be construed as an admission that it constitutes a prior industry with respect to the present invention. Although particular embodiments of the present invention have been illustrated and described, it will be apparent to those skilled in the industry that various changes and modifications can be made without departing from the spirit and scope of the invention. It has been intended, therefore, to cover in the appended claims all changes and modifications that are within the scope of the invention.

Claims (24)

NOVELTY OF THE INVENTION CLAIMS

1. - A method to treat keratinous tissue; said method comprises: a) heating a topical composition contained in a sac using a receptacle; said receptacle comprises: i) walls defining a cavity for releasably receiving at least one of the sacks; A heating system associated with one or more of one of the walls of the cavity; iii an energy source operatively associated with the heating system to provide sufficient energy to the heating system to moderately heat the composition to a predicted temperature; b) apply the moderately heated topical composition to the keratinous tissue.

2. The method according to claim 1, further characterized in that the composition comprises at least one active ingredient selected from the group comprising: active for desquamation; anti-acne assets; anti-wrinkle assets; antiatrophy assets; antioxidants; radical scavengers; chelating agents; flavonoids; anti-inflammatory agents; anti-cellulite agents; tanning assets; skin lightening agents; antimicrobial and antifungal assets; sun protection assets; conditioning agents; water soluble vitamins; particulate materials; amine sugars; vitamin B3 compounds; retinoids; peptides; phytosterols; hexamidines and their derivatives; dialkanoyl hydroxyproline compounds; salicylic acid compounds; n-acylamino acid compounds; dehydroacetic acid, its isomers, salts and derivatives thereof; skin firming agents, and mixtures of these.

3. The method according to claim 1 or 2, further characterized in that the topical composition has a viscosity of 10 to 500 Pa.s (10,000 to 500,000 cps) at the predicted temperature.

4. The method according to any of the preceding claims, further characterized in that by heating the composition moderately, its viscosity is kept within 20% of the viscosity it had before moderately heating it.

5. The method according to any of the preceding claims, further characterized in that the composition is solid at room temperature.

6. The method according to any of the preceding claims, further characterized in that the topical composition comprises a water-in-oil emulsion.

7. The method according to any of the preceding claims, further characterized in that the topical composition comprises at least 1% waxy materials.

8. A receptacle for moderately heating a topical composition contained in a sack; said receptacle comprises: i) walls defining a cavity for releasably receiving at least one of the sacks; ii) a heating system associated with one or more of one of the walls of the cavity, wherein the heating system has the ability to reach and maintain a predicted temperature for the topical composition; and iii) a power source operatively associated with the heating system for supplying power to said heating system.

The receptacle according to claim 8, further characterized in that the heating system is controlled by means of a regulator.

10. The receptacle according to claim 8 or 9, further characterized in that the receptacle also comprises an indicator; the indicator is operatively associated with the regulator to emit a signal when the predicted temperature is reached.

11. The receptacle according to any of claims 8 to 10; further characterized in that the receptacle also comprises a temperature sensor operatively associated with an indicator; the indicator produces a signal at the predicted temperature, wherein the signal is selected from the group comprising visual, auditory and tactile signals and combinations of these.

12. The receptacle according to any of claims 8 to 11, further characterized in that the heating system is activated by placing the bag in the cavity.

13. - The receptacle according to any of claims 8 to 11, further characterized in that the heating system is activated by means of a manual switch.

14. The receptacle according to any of claims 8 to 13, further characterized in that the heating system moderately heats the topical composition to its intended temperature, in 30 seconds to 5 minutes.

15. The receptacle according to any of claims 8 to 14, further characterized in that the heating system maintains the expected temperature of the composition for a predetermined period.

16. The receptacle according to any of claims 8 to 15, further characterized in that the heating system comprises: a) a heating element associated with the wall of the cavity adjacent to the power source; b) a heat sink operatively associated with the heating element; c) a sensor, of temperature in contact with the heatsink; and d) a regulator in contact with the temperature sensor; the monitor can interrupt the power supply from the power source to the heating element in a predetermined period.

17. The receptacle according to any of claims 8 to 16, further characterized in that the power source is supplied by a common AC / DC current in homes, battery, solar energy, combustible gases, chemical reaction, and any combination of these.

18. The receptacle according to any of claims 8 to 17, further characterized in that it comprises a timer.

19. The receptacle according to any of claims 8 to 17; further characterized in that said receptacle comprises an element selected from the group comprising sensors, switches and combinations thereof located on the walls of the cavity; the elements can communicate with one or more projections or points of contact on a surface of the bag.

20.- A case for the treatment of the keratinous tissue; said kit comprises: a) at least one topical composition; the composition comprises at least one active ingredient; b) at least one bag comprising surfaces defining at least one chamber for containing the composition; and c) a receptacle according to any of claims 8 to 19.

21. The kit according to claim 20 further characterized in that the bag contains a unit dose of the topical composition.

22. The kit according to claim 20 or 21, further characterized in that the bag contains 0.5 ml to 5 ml of the topical composition.

23. - The case according to any of claims 20 to 22, further characterized in that the heating system comprises a heating element associated with the wall of the cavity and a heat sink associated operatively with the heating element, and wherein when the bag placed in the receptacle deforms around the heat sink. 24.- A regime for skin care that includes: a) selecting a bag between several bags; each bag comprises at least one chamber containing a composition for skin care; b) inserting the bag into a receptacle according to any of claims 8 to 19; c) activating the heating system, and consequently moderately heating the composition contained in the bag; d) open the sack after moderately warming; e) applying the moderately heated composition to the keratinous tissue of a user at least once a day.