MXPA06000700A - Compuestos de sulfonildihidroimidazopiridinona como ligandos de 5-hidroxitriptamina-6. - Google Patents

Compuestos de sulfonildihidroimidazopiridinona como ligandos de 5-hidroxitriptamina-6.

Info

Publication number
MXPA06000700A
MXPA06000700A MXPA06000700A MXPA06000700A MXPA06000700A MX PA06000700 A MXPA06000700 A MX PA06000700A MX PA06000700 A MXPA06000700 A MX PA06000700A MX PA06000700 A MXPA06000700 A MX PA06000700A MX PA06000700 A MXPA06000700 A MX PA06000700A
Authority
MX
Mexico
Prior art keywords
sulfonyldihydroimid
azopyridinone
hydroxytryptamine
ligands
compounds
Prior art date
Application number
MXPA06000700A
Other languages
English (en)
Inventor
Ronald Charles Bernotas
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA06000700A publication Critical patent/MXPA06000700A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invencion proporciona un compuesto de la formula (I) y el uso del mismo en el tratamiento terapeutico de un trastorno del sistema nervioso central relacionado con o afectado por el receptor de 5-HT6(ver formula (I)).
MXPA06000700A 2003-07-23 2004-07-19 Compuestos de sulfonildihidroimidazopiridinona como ligandos de 5-hidroxitriptamina-6. MXPA06000700A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48941603P 2003-07-23 2003-07-23
PCT/US2004/023221 WO2005010003A1 (en) 2003-07-23 2004-07-19 Sulfonyldihydroimid- azopyridinone compounds as 5-hydroxytryptamine-6 ligands

Publications (1)

Publication Number Publication Date
MXPA06000700A true MXPA06000700A (es) 2006-04-11

Family

ID=34102868

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06000700A MXPA06000700A (es) 2003-07-23 2004-07-19 Compuestos de sulfonildihidroimidazopiridinona como ligandos de 5-hidroxitriptamina-6.

Country Status (9)

Country Link
US (2) US7291736B2 (es)
EP (1) EP1648891A1 (es)
JP (1) JP2006528184A (es)
CN (1) CN1849319A (es)
AU (1) AU2004259736A1 (es)
BR (1) BRPI0412868A (es)
CA (1) CA2532076A1 (es)
MX (1) MXPA06000700A (es)
WO (1) WO2005010003A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006268713A1 (en) * 2005-07-13 2007-01-18 F. Hoffmann-La Roche Ag Benzimidazole derivatives as 5-HT6,5-HT24
WO2008025736A1 (en) 2006-08-26 2008-03-06 Abbott Gmbh & Co. Kg Substituted benzimidazolone derivatives, medicaments comprising them and their use
EP2053052A1 (en) 2007-10-23 2009-04-29 Laboratorios del Dr. Esteve S.A. Process for the preparation of 6-substituted imidazo[2,1-b]thiazole-5-sulfonyl halide
EP3957284B1 (en) * 2008-01-29 2023-10-25 Implantica Patent Ltd Apparatus for treating obesity
EP2413929A4 (en) * 2009-04-02 2012-10-10 Zenyaku Kogyo Co Ltd PROCESS FOR TREATING COGNITIVE IMPAIRMENT
US9859455B2 (en) * 2013-02-08 2018-01-02 International Business Machines Corporation Interdigitated back contact heterojunction photovoltaic device with a floating junction front surface field
BR112018010216B1 (pt) 2015-11-20 2024-02-15 Forma Therapeutics, Inc Purinonas como inibidores da protease específica da ubiquitina 1 e composição farmacêutica compreendendo os referidos compostos
CN112689637B (zh) * 2018-09-13 2023-11-10 橘生药品工业株式会社 咪唑并吡啶酮化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE422799B (sv) * 1975-05-28 1982-03-29 Merck & Co Inc Analogiforfarande for framstellning av 1,3-dihydroimidazo (4,5-b)pyridin-2-oner
US5288749A (en) 1991-12-20 1994-02-22 Abbott Laboratories Tertiary and secondary amines as alpha-2 antagonists and serotonin uptake inhibitors
FR2708608B1 (fr) * 1993-07-30 1995-10-27 Sanofi Sa Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant.
DE69628804T2 (de) 1995-12-08 2003-12-18 Pfizer Substitutierte heterozyclische Derivate als CRF Antagonisten
GB9820113D0 (en) * 1998-09-15 1998-11-11 Merck Sharp & Dohme Therapeutic agents
WO2001027104A1 (fr) 1999-10-13 2001-04-19 Banyu Pharmaceutical Co., Ltd. Derives d'imidazolidinone a substitution
DE10012401A1 (de) * 2000-03-15 2001-09-27 Sigurd Lenzen Arylsulfonylbenzimidazoione und Arylsulfonylhydantoine als Steigerer der Insulinsekretion
CN1281605C (zh) * 2000-12-22 2006-10-25 惠氏公司 作为5－羟色胺－6配基的杂环基－吲唑或氮杂吲唑化合物

Also Published As

Publication number Publication date
AU2004259736A1 (en) 2005-02-03
CN1849319A (zh) 2006-10-18
BRPI0412868A (pt) 2006-10-03
US7608717B2 (en) 2009-10-27
US20050020596A1 (en) 2005-01-27
US20080070943A1 (en) 2008-03-20
WO2005010003A1 (en) 2005-02-03
EP1648891A1 (en) 2006-04-26
JP2006528184A (ja) 2006-12-14
CA2532076A1 (en) 2005-02-03
US7291736B2 (en) 2007-11-06

Similar Documents

Publication Publication Date Title
MXPA05008438A (es) Heterociclil-3-sulfonilindazoles como ligandos de 5-hidroxitriptamina-6.
MXPA06000701A (es) Compuestos de sulfonildihidrobencimidazolona como ligandos de 5-hidroxitriptamina-6.
NO20050007L (no) 1-Heterosyklylalkyl-3-sulfonylazaindol eller -azaindazolderivater som 5-hydroksytryptamin-6 ligander
NO20050014L (no) 1-Heterosyklylalkyl-3-sulfonylindol eller -indazolderivater som 5-hydroksytryptamin-6 ligander
MXPA04005886A (es) Derivados de azaindolilalquilamina como ligandos de 5-hidroxitirptamina-6.
IS2517B (is) Notkun á setnum 2-amínótetralínum í fyrirbyggjandi meðferð á Parkinsons-veiki
UA74443C2 (uk) Ліганди 5-нт рецептора та їх використання
GEP20084550B (en) Substituted morpholine compounds for the treatment of central nervous system disorders
WO2002051837A3 (en) Heterocyclindazole and azaindazole compounds as 5-hydroxytryptamine-6 ligands
MXPA05013294A (es) Ligandos del receptor de cannabinoides y usos de los mismos.
WO2007142905A3 (en) 1-sulfonylindazolylamine and -amide derivatives as 5-hydroxytryptamine-6 ligands
WO2002036562A3 (en) 1-aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands
TW200531689A (en) Therapeutic agents
UA92503C2 (ru) Соединения 5-(фенилизоксазолилэтокси)-триазол-3-ил-замещенного пиридина для лечения неврологических, психиатрических или болевых расстройств
MXPA05011922A (es) Ligandos del receptor de cannabinoides y sus usos.
TW200504034A (en) Therapeutic agents
MXPA04003087A (es) Derivados de cromano como ligados de 5-hidroxitriptamina-6.
WO2002051832A3 (en) Heterocyclylalkylindole or -azaindole compounds as 5-hydroxytryptamine-6 ligands
UA94053C2 (ru) Замещенные производные 3-сульфонилиндазола в качестве лигандов гидрокситриптамина-6
MX2008002158A (es) Derivados de azinil-3-sulfonilindazol como ligandos de 5-hidroxitriptamina-6.
MXPA06000957A (es) Compuestos de n-sulfonil heterociclopirrolilalquilamina como ligandos de 5-hidroxitriptamina-6.
WO2002085853A3 (en) Heterocyclylalkoxy-, -alkylthio- and -alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands
MX2008013053A (es) Derivados de dihidri[1,4]oxazino[2,3,4-hi]indazol-sustituidos como ligandos de 5-hidroxitriptamina-6.
MXPA05010651A (es) Compuestos de pirazol.
MXPA06000700A (es) Compuestos de sulfonildihidroimidazopiridinona como ligandos de 5-hidroxitriptamina-6.