MXPA05009179A - Sistema para suministro de opioides. - Google Patents

Sistema para suministro de opioides.

Info

Publication number
MXPA05009179A
MXPA05009179A MXPA05009179A MXPA05009179A MXPA05009179A MX PA05009179 A MXPA05009179 A MX PA05009179A MX PA05009179 A MXPA05009179 A MX PA05009179A MX PA05009179 A MXPA05009179 A MX PA05009179A MX PA05009179 A MXPA05009179 A MX PA05009179A
Authority
MX
Mexico
Prior art keywords
opioid
administration
formulation
pulmonary
delivery system
Prior art date
Application number
MXPA05009179A
Other languages
English (en)
Inventor
Steven Louis Shafer
Original Assignee
Delex Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delex Therapeutics Inc filed Critical Delex Therapeutics Inc
Publication of MXPA05009179A publication Critical patent/MXPA05009179A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes

Abstract

Se expone una preparacion de opioides para administracion pulmonar en el tratamiento o manejo del dolor, un dispositivo para suministro de farmacos pulmonares que la contienen, el metodo de administracion, el equipo que la contiene, y los usos de la misma. La preparacion contiene al menos un opoide de inicio rapido y de referencia contiene tambien un opiode de efecto sostenido para reducir la frecuencia de administracion. La invencion emplea los efectos secundarios de la preparacion de opioides para permitir que los pacientes se auto-moderen en la ingestion del farmaco, evitando con esto la toxicidad mientras que alcancen la analgesia. Se emplea un modelo farmacocinetico y farmacodinamico para determinar las preparaciones optimas del farmaco y los parametros optimos para la administracion.
MXPA05009179A 2003-02-28 2004-03-01 Sistema para suministro de opioides. MXPA05009179A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45033303P 2003-02-28 2003-02-28
PCT/CA2004/000303 WO2004075879A1 (en) 2003-02-28 2004-03-01 Opioid delivery system

Publications (1)

Publication Number Publication Date
MXPA05009179A true MXPA05009179A (es) 2006-03-08

Family

ID=32927636

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009179A MXPA05009179A (es) 2003-02-28 2004-03-01 Sistema para suministro de opioides.

Country Status (20)

Country Link
EP (1) EP1603533B1 (es)
JP (1) JP2006519185A (es)
KR (1) KR20050114221A (es)
CN (1) CN1780605A (es)
AT (1) ATE428402T1 (es)
AU (1) AU2004216550B2 (es)
BR (1) BRPI0408059A (es)
CA (1) CA2556629A1 (es)
CY (1) CY1109215T1 (es)
DE (1) DE602004020597D1 (es)
DK (1) DK1603533T3 (es)
ES (1) ES2325834T3 (es)
HK (1) HK1084341A1 (es)
IL (1) IL177764A0 (es)
MX (1) MXPA05009179A (es)
NZ (1) NZ542005A (es)
PT (1) PT1603533E (es)
RU (1) RU2362559C2 (es)
WO (1) WO2004075879A1 (es)
ZA (1) ZA200607418B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2039360A1 (en) * 2007-09-19 2009-03-25 Euro-Celtique S.A. Non-invasive direct delivery of opioids to the central nervous system
GB0919893D0 (en) * 2009-11-13 2009-12-30 Biocopea Ltd Drug composition and its use in therapy
KR101298303B1 (ko) * 2010-04-27 2013-08-20 울산대학교 산학협력단 약물의 약동-약력학적 모델링을 위한 통합 분석 시스템
DE102012009617B4 (de) * 2012-05-15 2020-03-26 Drägerwerk AG & Co. KGaA Datenverarbeitungseinrichtung für eine Anästhesievorrichtung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8900267D0 (en) * 1989-01-06 1989-03-08 Riker Laboratories Inc Narcotic analgesic formulations and apparatus containing same
US5451408A (en) * 1994-03-23 1995-09-19 Liposome Pain Management, Ltd. Pain management with liposome-encapsulated analgesic drugs
WO1995031182A1 (en) * 1994-05-13 1995-11-23 Aradigm Corporation Narcotic containing aerosol formulation
GB9606188D0 (en) * 1996-03-23 1996-05-29 Danbiosyst Uk Pollysaccharide microspheres for the pulmonary delivery of drugs
CA2354576C (en) * 1998-12-11 2008-10-14 Pharmachemie B.V. Pharmaceutical preparation for inhalation of an opioid
EP1392262A1 (en) * 2001-05-24 2004-03-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
US7766013B2 (en) * 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device

Also Published As

Publication number Publication date
EP1603533B1 (en) 2009-04-15
ES2325834T3 (es) 2009-09-21
CN1780605A (zh) 2006-05-31
WO2004075879A1 (en) 2004-09-10
DE602004020597D1 (de) 2009-05-28
NZ542005A (en) 2009-05-31
AU2004216550A1 (en) 2004-09-10
JP2006519185A (ja) 2006-08-24
EP1603533A1 (en) 2005-12-14
ZA200607418B (en) 2008-01-30
KR20050114221A (ko) 2005-12-05
AU2004216550B2 (en) 2010-06-03
ATE428402T1 (de) 2009-05-15
CA2556629A1 (en) 2004-09-10
PT1603533E (pt) 2009-07-23
IL177764A0 (en) 2007-03-08
DK1603533T3 (da) 2009-08-17
BRPI0408059A (pt) 2006-02-14
RU2005130166A (ru) 2006-06-10
CY1109215T1 (el) 2014-07-02
RU2362559C2 (ru) 2009-07-27
HK1084341A1 (en) 2006-07-28

Similar Documents

Publication Publication Date Title
WO2006023989A3 (en) Gas delivery and monitoring system
SE0102276D0 (sv) Device and method for the administration of a medicament
TW200505881A (en) Tri(cyclo) substituted amide compounds
NZ513304A (en) Combinations of formoterol and a tiotropium salt
IL176449A0 (en) Generally linear effervescent oral fentanyl dosage form and methods of administering
SE0201669D0 (sv) New formulation and use thereof
IT1317846B1 (it) Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
AU1079701A (en) Oral transmucosal drug dosage using solid solution
EP1708685A4 (en) GALENIC FORMS OF EFFERVESCENT ORAL OPIATES AND METHODS OF ADMINISTERING OPIATES
LT2001119A (en) Pharmaceutical formulations comprising intranasal morphine and use thereof
BG104797A (en) Use of dexmedetomi dine for sedative effect in patients in an intensive care unit
CY1109215T1 (el) Συστημα χορηγησης οπιοειδους
WO2005044187A3 (en) Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same
MXPA06003122A (es) Composiciones farmaceuticas y procedimientos que comprenden combinaciones de derivados de 2-alquiliden-19-nor-vitamina d y un agonista/antagonista de estrogenos.
GB0201367D0 (en) Composition
DK1137398T3 (da) Farmaceutisk præparat til inhalation af et opioid
GEP201606538B (en) Preoperative treatment of post operative pain
WO2007127683A3 (en) Administration of agonist-antagonist in opioid-dependent patients
TW200517119A (en) Method of treatment using interferon-tau
NO20064463L (no) Opioid leveringssystem
EP1622450A4 (en) PROCESS FOR PROMOTING UNINTERRUPTED SLEEP BY ADMINISTERING TROPIUM CHLORIDE
TW200500085A (en) Sustained-release pharmaceutical composition for lung administration
BRPI0418582A (pt) sistema de administração de opióides
WO2001068140A3 (en) Opioid formulations
SE9904424D0 (sv) Use of interleukin-6 in combination with leptin in treatment of obesity

Legal Events

Date Code Title Description
FG Grant or registration
GB Transfer or rights