MXPA05007651A - Composiciones y metodos para la inhibicion por arnsi de la molecula de adhesion intercelular-1. - Google Patents

Composiciones y metodos para la inhibicion por arnsi de la molecula de adhesion intercelular-1.

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Publication number
MXPA05007651A
MXPA05007651A MXPA05007651A MXPA05007651A MXPA05007651A MX PA05007651 A MXPA05007651 A MX PA05007651A MX PA05007651 A MXPA05007651 A MX PA05007651A MX PA05007651 A MXPA05007651 A MX PA05007651A MX PA05007651 A MXPA05007651 A MX PA05007651A
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MX
Mexico
Prior art keywords
icam
compositions
methods
small interfering
interfering rnas
Prior art date
Application number
MXPA05007651A
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English (en)
Inventor
Michael J Tolentino
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of MXPA05007651A publication Critical patent/MXPA05007651A/es

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    • C12N2310/14—Type of nucleic acid interfering N.A.

Abstract

La interferencia de ARN usando pequenos ARN de interferencia que son especificos para el gen ICAM-1 inhibe la expresion de este gen; enfermedades que implican la adhesion de celulas mediada por ICAM-1, tales como enfermedades inflamatorias y autoinmunes, retinopatia diabetica y otras complicaciones que surgen de la diabetes de tipo I, degeneracion macular relacionada con la edad y muchos tipos de cancer, pueden ser tratadas administrando los pequenos ARN de interferencia.
MXPA05007651A 2003-01-16 2004-01-16 Composiciones y metodos para la inhibicion por arnsi de la molecula de adhesion intercelular-1. MXPA05007651A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44057903P 2003-01-16 2003-01-16
PCT/US2004/001166 WO2004065546A2 (en) 2003-01-16 2004-01-16 COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF ICAM-1

Publications (1)

Publication Number Publication Date
MXPA05007651A true MXPA05007651A (es) 2005-10-26

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MXPA05007651A MXPA05007651A (es) 2003-01-16 2004-01-16 Composiciones y metodos para la inhibicion por arnsi de la molecula de adhesion intercelular-1.

Country Status (9)

Country Link
US (4) US20040220129A1 (es)
EP (2) EP2251434B1 (es)
JP (1) JP2007524349A (es)
AT (1) ATE477337T1 (es)
AU (1) AU2004205895B2 (es)
CA (1) CA2513623A1 (es)
DE (1) DE602004028587D1 (es)
MX (1) MXPA05007651A (es)
WO (1) WO2004065546A2 (es)

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US20110092571A1 (en) 2011-04-21
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US7847090B2 (en) 2010-12-07
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EP2251434A1 (en) 2010-11-17
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DE602004028587D1 (de) 2010-09-23

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