MXPA04012630A - Proceso para preparar derivados de acido 5-(1,3-oxazol-2-il)benzoico. - Google Patents
Proceso para preparar derivados de acido 5-(1,3-oxazol-2-il)benzoico.Info
- Publication number
- MXPA04012630A MXPA04012630A MXPA04012630A MXPA04012630A MXPA04012630A MX PA04012630 A MXPA04012630 A MX PA04012630A MX PA04012630 A MXPA04012630 A MX PA04012630A MX PA04012630 A MXPA04012630 A MX PA04012630A MX PA04012630 A MXPA04012630 A MX PA04012630A
- Authority
- MX
- Mexico
- Prior art keywords
- oxazol
- preparing
- benzoic acid
- acid derivatives
- formula iii
- Prior art date
Links
- IMAITKPPSLYKDS-UHFFFAOYSA-N 3-(1,3-oxazol-2-yl)benzoic acid Chemical class OC(=O)C1=CC=CC(C=2OC=CN=2)=C1 IMAITKPPSLYKDS-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical group [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 150000002916 oxazoles Chemical class 0.000 abstract 1
- 235000005074 zinc chloride Nutrition 0.000 abstract 1
- 239000011592 zinc chloride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39028502P | 2002-06-20 | 2002-06-20 | |
| US45047803P | 2003-02-27 | 2003-02-27 | |
| PCT/US2003/019585 WO2004000821A1 (en) | 2002-06-20 | 2003-06-20 | Process for preparing 5-(1, 3-oxazol-2-yl) benzoic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04012630A true MXPA04012630A (es) | 2005-09-30 |
Family
ID=30003150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04012630A MXPA04012630A (es) | 2002-06-20 | 2003-06-20 | Proceso para preparar derivados de acido 5-(1,3-oxazol-2-il)benzoico. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7115747B2 (https=) |
| EP (1) | EP1532123B1 (https=) |
| JP (1) | JP2005533811A (https=) |
| CN (1) | CN1324017C (https=) |
| AT (1) | ATE370131T1 (https=) |
| AU (1) | AU2003249344A1 (https=) |
| BR (1) | BR0312439A (https=) |
| CA (1) | CA2489988A1 (https=) |
| CO (1) | CO5670350A2 (https=) |
| DE (1) | DE60315664D1 (https=) |
| EA (1) | EA008389B1 (https=) |
| IL (1) | IL165763A0 (https=) |
| MX (1) | MXPA04012630A (https=) |
| NO (1) | NO20045497L (https=) |
| NZ (1) | NZ537390A (https=) |
| PL (1) | PL374999A1 (https=) |
| WO (1) | WO2004000821A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7351738B2 (en) * | 2002-11-27 | 2008-04-01 | Elan Pharmaceuticals, Inc. | Substituted ureas and carbamates |
| TW200738701A (en) | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
| US7872009B2 (en) * | 2005-11-21 | 2011-01-18 | Amgen Inc. | Beta-Secretase modulators and methods of use |
| WO2007061670A1 (en) | 2005-11-21 | 2007-05-31 | Amgen Inc. | Beta-secretase modulators and methods of use |
| US7838676B2 (en) | 2005-11-21 | 2010-11-23 | Amgen Inc. | Beta-secretase modulators and methods of use |
| US7745484B2 (en) | 2005-11-21 | 2010-06-29 | Amgen Inc. | Beta-secretase modulators and methods of use |
| US20080277393A1 (en) * | 2007-05-07 | 2008-11-13 | True Charles W | Collapsible, stackable, semi-rigid universal cotainer for hazardous and non-hazardous goods |
| US8163909B2 (en) | 2007-05-25 | 2012-04-24 | Amgen Inc. | Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use |
| CA2687608C (en) | 2007-05-25 | 2013-07-02 | Amgen Inc. | Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use |
| US7803809B2 (en) | 2008-11-12 | 2010-09-28 | Amgen Inc. | Substituted pyrano [2,3-b] pyridinamine compounds as beta-secretase modulators and methods of use |
| CA2736130C (en) | 2008-09-11 | 2014-01-14 | Amgen Inc. | Spiro-tetracyclic ring compounds as beta-secretase modulators and methods of use |
| EP2504330A1 (en) | 2009-11-23 | 2012-10-03 | Amgen Inc. | Amino heteroaryl compounds as beta-secretase modulators and methods of use |
| US9296698B2 (en) | 2009-11-23 | 2016-03-29 | Amgen Inc. | Amino heteroaryl compounds as beta-secretase modulators and methods of use |
| AU2011207679B2 (en) | 2010-01-19 | 2013-10-10 | Amgen Inc. | Amino heteroaryl compounds as beta-secretase modulators and methods of use |
| MX2012010657A (es) | 2010-03-15 | 2013-02-07 | Amgen Inc | Compuestos de espiro amino-dihidrooxazina y amino-dihidrotiazina como moduladores de beta-secretasa y su uso medico. |
| EP2547685A1 (en) | 2010-03-15 | 2013-01-23 | Amgen Inc. | Spiro-tetracyclic ring compounds as beta - secretase modulators |
| EP2673279A1 (en) | 2011-02-07 | 2013-12-18 | Amgen Inc. | 5-amino-oxazepine and 5-amino-thiazepane compounds as beta-secretase antagonists and methods of use |
| WO2013044092A1 (en) | 2011-09-21 | 2013-03-28 | Amgen Inc. | Amino-oxazines and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use |
| WO2014078314A1 (en) | 2012-11-15 | 2014-05-22 | Amgen Inc. | Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use |
| US9462841B1 (en) | 2016-03-01 | 2016-10-11 | William Popejoy | Protective headgear and shoulder pad apparatus and methods |
| US11272751B2 (en) | 2016-03-01 | 2022-03-15 | Nicholas Popejoy | Protective headgear, impact diffusing systems and methods |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20020276A1 (es) | 2000-06-30 | 2002-04-06 | Elan Pharm Inc | COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER |
| CA2462851A1 (en) * | 2001-10-04 | 2003-04-10 | Elan Pharmaceuticals, Inc. | Hydroxypropylamines |
| NZ533107A (en) * | 2001-11-08 | 2007-04-27 | Upjohn Co | N, N'-substituted-1,3-diamino-2-hydroxypropane derivatives |
| GB0325830D0 (en) * | 2003-11-05 | 2003-12-10 | Novartis Ag | Organic compounds |
-
2003
- 2003-06-20 PL PL03374999A patent/PL374999A1/xx unknown
- 2003-06-20 MX MXPA04012630A patent/MXPA04012630A/es active IP Right Grant
- 2003-06-20 WO PCT/US2003/019585 patent/WO2004000821A1/en not_active Ceased
- 2003-06-20 NZ NZ537390A patent/NZ537390A/en unknown
- 2003-06-20 BR BR0312439-8A patent/BR0312439A/pt not_active IP Right Cessation
- 2003-06-20 AT AT03761206T patent/ATE370131T1/de not_active IP Right Cessation
- 2003-06-20 EA EA200401510A patent/EA008389B1/ru unknown
- 2003-06-20 AU AU2003249344A patent/AU2003249344A1/en not_active Abandoned
- 2003-06-20 CA CA002489988A patent/CA2489988A1/en not_active Abandoned
- 2003-06-20 CN CNB038144476A patent/CN1324017C/zh not_active Expired - Fee Related
- 2003-06-20 EP EP03761206A patent/EP1532123B1/en not_active Expired - Lifetime
- 2003-06-20 JP JP2004516055A patent/JP2005533811A/ja active Pending
- 2003-06-20 US US10/600,100 patent/US7115747B2/en not_active Expired - Fee Related
- 2003-06-20 DE DE60315664T patent/DE60315664D1/de not_active Expired - Lifetime
-
2004
- 2004-12-14 IL IL16576304A patent/IL165763A0/xx unknown
- 2004-12-16 NO NO20045497A patent/NO20045497L/no not_active Application Discontinuation
-
2005
- 2005-01-20 CO CO05004558A patent/CO5670350A2/es not_active Application Discontinuation
-
2006
- 2006-10-03 US US11/538,155 patent/US20070105921A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EA008389B1 (ru) | 2007-04-27 |
| EP1532123A1 (en) | 2005-05-25 |
| WO2004000821A1 (en) | 2003-12-31 |
| CN1662510A (zh) | 2005-08-31 |
| JP2005533811A (ja) | 2005-11-10 |
| BR0312439A (pt) | 2005-05-10 |
| CN1324017C (zh) | 2007-07-04 |
| CA2489988A1 (en) | 2003-12-31 |
| US20040063965A1 (en) | 2004-04-01 |
| NZ537390A (en) | 2006-07-28 |
| DE60315664D1 (de) | 2007-09-27 |
| NO20045497L (no) | 2005-03-07 |
| ATE370131T1 (de) | 2007-09-15 |
| EP1532123B1 (en) | 2007-08-15 |
| CO5670350A2 (es) | 2006-08-31 |
| US20070105921A1 (en) | 2007-05-10 |
| AU2003249344A1 (en) | 2004-01-06 |
| EA200401510A1 (ru) | 2005-06-30 |
| PL374999A1 (en) | 2005-11-14 |
| NO20045497D0 (no) | 2004-12-16 |
| US7115747B2 (en) | 2006-10-03 |
| IL165763A0 (en) | 2006-01-15 |
| HK1081543A1 (zh) | 2006-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |