MXPA04004479A - Composiciones topicas que contienen enzimas estabilizadas con inhibidores. - Google Patents

Composiciones topicas que contienen enzimas estabilizadas con inhibidores.

Info

Publication number
MXPA04004479A
MXPA04004479A MXPA04004479A MXPA04004479A MXPA04004479A MX PA04004479 A MXPA04004479 A MX PA04004479A MX PA04004479 A MXPA04004479 A MX PA04004479A MX PA04004479 A MXPA04004479 A MX PA04004479A MX PA04004479 A MXPA04004479 A MX PA04004479A
Authority
MX
Mexico
Prior art keywords
skin
enzyme
leave
personal care
inhibitors
Prior art date
Application number
MXPA04004479A
Other languages
English (en)
Inventor
Charles Winston Sauders
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MXPA04004479A publication Critical patent/MXPA04004479A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212Face masks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/45Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00Manicure or pedicure preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se presenta composiciones para el cuidado personal para usa y no enjuagar que comprenden una enzima estabilizada, al menos 30% de agua, menos de 5% de una sal de metal alcalinoterreo y un inhibidor de enzima que tiene una constante de inhibicion (Ki) de 10 nanomolar (nm) a 25,000nm. Se presenta tambien un metodo para proporcionar beneficios de cuidado de la piel, por ejemplo, sensacion y/o apariencia de la piel, de preferencia, humectacion, suavidad y/o lisura de la piel; el metodo comprende aplicar en forma topica, a la piel que necesita el beneficio de cuidado de la piel, una cantidad segura y eficaz de las composiciones de la invencion que se describe en la presente. Se presenta ademas un metodo para proporcionar a un consumidor un producto para el cuidado personal, para aplicar y no enjuagar, que contienen enzimas, en donde las enzimas estan inhibidas e inactivas en el anaquel, pero se activan sobre la piel sin necesidad de una etapa separada de reactivacion, de preferencia, en donde el producto para el cuidado personal, para aplicar y no enjuagar, que contienen enzimas comprende una de las composiciones de la invencion que se describen en la presente.
MXPA04004479A 2001-11-13 2002-11-07 Composiciones topicas que contienen enzimas estabilizadas con inhibidores. MXPA04004479A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33814901P 2001-11-13 2001-11-13
PCT/US2002/035765 WO2003041680A1 (en) 2001-11-13 2002-11-07 Topical compositions containing enzymes stabilized with inhibitors

Publications (1)

Publication Number Publication Date
MXPA04004479A true MXPA04004479A (es) 2004-08-11

Family

ID=23323604

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04004479A MXPA04004479A (es) 2001-11-13 2002-11-07 Composiciones topicas que contienen enzimas estabilizadas con inhibidores.

Country Status (6)

Country Link
US (1) US20030157088A1 (es)
EP (1) EP1446096A1 (es)
JP (1) JP2005515180A (es)
CN (1) CN1612723A (es)
MX (1) MXPA04004479A (es)
WO (1) WO2003041680A1 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2196205A1 (en) 2001-11-14 2010-06-16 Rutgers, The State University Topoisomerase poisons
KR100506543B1 (ko) * 2003-08-14 2005-08-05 주식회사 제닉 온도 감응성 상태변화 하이드로겔 조성물 및 그 제조방법
FR2864784B1 (fr) * 2004-01-06 2006-02-10 Oreal Composition cosmetique comprenant un organopolysiloxane elastomere et un compose amino-sulfonique
JP2007519408A (ja) * 2004-01-30 2007-07-19 ビーエーエスエフ アクチェンゲゼルシャフト 安定化された酵素製剤
US20060099567A1 (en) * 2004-04-08 2006-05-11 Biomatrica, Inc. Integration of sample storage and sample management for life science
JP4896006B2 (ja) * 2004-04-08 2012-03-14 バイオマトリカ, インコーポレイテッド ライフサイエンスのためのサンプル保存とサンプル管理との統合
US20080176209A1 (en) * 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
JP2008522625A (ja) * 2004-12-09 2008-07-03 ダウ グローバル テクノロジーズ インコーポレイティド 酵素安定化
US20060134234A1 (en) * 2004-12-17 2006-06-22 L'oreal Cosmetic composition
EP1965763B1 (en) 2005-12-27 2019-11-06 Ramot at Tel Aviv University Ltd. Stable enzymatic preparations and methods of use thereof
DE102006015960A1 (de) * 2006-04-04 2007-10-11 Qiagen Gmbh Gemisch reversibel inhibierter Enzyme
US20080059313A1 (en) * 2006-08-30 2008-03-06 Oblong John E Hair care compositions, methods, and articles of commerce that can increase the appearance of thicker and fuller hair
CN101646760B (zh) 2007-03-27 2014-11-26 诺维信公司 稳定的酶溶液和制造方法
DE102007057583A1 (de) * 2007-11-28 2009-06-04 Henkel Ag & Co. Kgaa Waschmittel mit stabilisierten Enzymen
EP2364692B1 (fr) * 2007-11-30 2017-10-25 Galderma Research & Development Compositions comprenant au moins un derive de l'acide naphtoïque, du peroxyde de benzoyle et au moins un agent filmogene, leurs procedes de preparation, et leurs utilisations
ES2646787T3 (es) * 2008-02-29 2017-12-18 The Procter & Gamble Company Composiciones para el cuidado del cabello y métodos para aumentar el diámetro del cabello
RU2510662C2 (ru) * 2008-03-26 2014-04-10 Новозимс А/С Стабилизированные жидкие ферментные композиции
RU2541786C2 (ru) * 2008-06-06 2015-02-20 ДАНИСКО ЮЭс ИНК. Композиции и способы, включающие варианты микробных протеаз
US20100105742A1 (en) * 2008-10-24 2010-04-29 Conopco, Inc., D/B/A Unilever Pearlescent liquid cosmetic composition
EP2430195B1 (en) * 2009-05-11 2019-01-23 Biomatrica, INC. Compositions and methods for biological sample storage
EP2598661B1 (en) 2010-07-26 2017-09-27 Biomatrica, INC. Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
CA2806670A1 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
EP2471554A1 (en) 2010-12-28 2012-07-04 Hexal AG Pharmaceutical formulation comprising a biopharmaceutical drug
US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
US10123966B2 (en) 2013-05-16 2018-11-13 The Procter And Gamble Company Hair thickening compositions and methods of use
CN111317681A (zh) 2013-09-05 2020-06-23 宝洁公司 头皮护理组合物
WO2015148603A1 (en) * 2014-03-26 2015-10-01 Momentive Performance Materials Inc. Silylated surfactants in personal care and home care
US9549885B2 (en) 2014-04-24 2017-01-24 The Procter & Gamble Company Scalp care composition
EP3942931A1 (en) 2014-06-10 2022-01-26 Biomatrica, INC. Stabilization of thrombocytes at ambient temperatures
EP3234093B1 (en) 2014-12-19 2020-05-27 Novozymes A/S Protease variants and polynucleotides encoding same
EP3387411B1 (en) 2015-12-08 2023-05-10 Biomatrica, INC. Reduction of erythrocyte sedimentation rate
GB2568920A (en) * 2017-11-30 2019-06-05 Jenarron Therapeutics Ltd Stable wound care formulation
CN111818901A (zh) * 2018-04-05 2020-10-23 拜尔斯道夫股份有限公司 用于快速汗液蒸发的化妆品组合物
US10463596B1 (en) 2018-06-28 2019-11-05 The Procter And Gamble Company Scalp care composition with well dispersed particulate scalp benefit agents
CN114028245B (zh) * 2021-11-29 2024-03-26 浙江宜格企业管理集团有限公司 一种温和去角质组合物及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4318818A (en) * 1979-11-09 1982-03-09 The Procter & Gamble Company Stabilized aqueous enzyme composition
US5000939A (en) * 1984-06-12 1991-03-19 Colgate-Palmolive Company Dentifrice containing stabilized enzyme
DK204290D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Enzymatisk detergentkomposition og fremgangsmaade til enzymstabilisering
US5354491A (en) * 1992-08-14 1994-10-11 The Procter & Gamble Company Liquid detergent compositions containing protease and certain β-aminoalkylboronic acids and esters
DK0583534T3 (da) * 1992-08-14 1997-06-16 Procter & Gamble Flydende detergenter, der indeholder et peptidaldehyd
EP0751991A1 (en) * 1994-03-22 1997-01-08 The Procter & Gamble Company Protease enzyme manufacture using non-protein protease inhibitors
US6013255A (en) * 1994-04-18 2000-01-11 Gist-Brocades B.V. Stable water-in-oil emulsions
FR2737115B1 (fr) * 1995-07-25 1997-08-22 Oreal Composition stable contenant une enzyme
JP2000506393A (ja) * 1996-09-24 2000-05-30 ザ、プロクター、エンド、ギャンブル、カンパニー プロテアーゼ、及びペプチドプロテアーゼインヒビターを融合したそれらの変種
AR020106A1 (es) * 1998-06-26 2002-04-10 Procter & Gamble Variantes estabilizadas del inhibidor de la subtilisina de streptomyces, gen mutante que la codifica y composicion que comprende dicha variante
DE19829789A1 (de) * 1998-07-03 2000-01-05 Beiersdorf Ag Gegen Akne und entzündete Comedonen wirksame Zubereitungen enthaltend Serin-Proteasen und ein oder mehrere Calciumsalze
GB2360041B (en) * 2000-03-11 2003-01-22 Reckitt Benckiser Inc Storage stable concentrated cleaning solution

Also Published As

Publication number Publication date
CN1612723A (zh) 2005-05-04
EP1446096A1 (en) 2004-08-18
US20030157088A1 (en) 2003-08-21
WO2003041680A1 (en) 2003-05-22
JP2005515180A (ja) 2005-05-26

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