MXPA04003072A - Procedimiento para preparar compuestos de bencenosulfonilo. - Google Patents

Procedimiento para preparar compuestos de bencenosulfonilo.

Info

Publication number
MXPA04003072A
MXPA04003072A MXPA04003072A MXPA04003072A MXPA04003072A MX PA04003072 A MXPA04003072 A MX PA04003072A MX PA04003072 A MXPA04003072 A MX PA04003072A MX PA04003072 A MXPA04003072 A MX PA04003072A MX PA04003072 A MXPA04003072 A MX PA04003072A
Authority
MX
Mexico
Prior art keywords
preparation
present disclosure
compounds
preparing
preparing benzenesulfonyl
Prior art date
Application number
MXPA04003072A
Other languages
English (en)
Inventor
Laughlin Kathleen Mc
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of MXPA04003072A publication Critical patent/MXPA04003072A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/04—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups
    • C07C303/08—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups by reaction with halogenosulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente exposicion proporciona un procedimiento para la preparacion de haluros de sulfonilo aromaticos poniendo en contacto un compuesto fenilo sustituido con un acido halosulfonico y acido trifluoroacetico; la presente exposicion proporciona ademas un procedimiento para la preparacion de 4-?5-metil-3-fenilisoxasol-4-il?bencenosulfonamida, que es util en el tratamiento de trastornos relacionados con la ciclooxigenasa-2.
MXPA04003072A 2001-10-02 2002-10-02 Procedimiento para preparar compuestos de bencenosulfonilo. MXPA04003072A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32667701P 2001-10-02 2001-10-02
PCT/US2002/031445 WO2003029230A1 (en) 2001-10-02 2002-10-02 Method for preparing benzenesulfonyl compounds

Publications (1)

Publication Number Publication Date
MXPA04003072A true MXPA04003072A (es) 2004-09-06

Family

ID=23273211

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04003072A MXPA04003072A (es) 2001-10-02 2002-10-02 Procedimiento para preparar compuestos de bencenosulfonilo.

Country Status (16)

Country Link
US (1) US20030105334A1 (es)
EP (1) EP1438300A1 (es)
JP (1) JP2005509608A (es)
KR (1) KR20040085135A (es)
CN (1) CN1308315C (es)
AU (2) AU2002337804B2 (es)
BR (1) BR0213027A (es)
CA (1) CA2462297C (es)
HK (1) HK1069578A1 (es)
IL (2) IL161086A0 (es)
MX (1) MXPA04003072A (es)
PL (1) PL369676A1 (es)
RS (1) RS34904A (es)
RU (1) RU2284324C2 (es)
WO (1) WO2003029230A1 (es)
ZA (1) ZA200402472B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535951A (en) * 2002-03-15 2006-02-24 Pharmacia Corp Crystalline parecoxib sodium
HUP0302219A2 (hu) * 2003-07-16 2005-03-29 Richter Gedeon Vegyészeti Gyár Rt. N-hidroxi-4-(3-fenil-5-metil-izoxazol-4-il)-benzolszulfonamid-szolvátok, eljárás előállításukra és alkalmazásuk
CA2491332A1 (en) * 2003-12-30 2005-06-30 Dr. Reddy's Laboratories Ltd. Method for preparing diaryl-substituted isoxazole compounds
ITMI20040019A1 (it) * 2004-01-12 2004-04-12 Univ Bari Derivati isossazolici e loro impiego come inibitori della ciclossigenasi
WO2005085218A1 (en) * 2004-03-05 2005-09-15 Chandiran Thakashinamoorthy A novel process for preparing valdecoxib
US7989450B2 (en) 2008-01-11 2011-08-02 Universita' Degli Studi Di Bari Functionalized diarylisoxazoles inhibitors of ciclooxygenase
CN102329277B (zh) * 2011-10-24 2013-08-07 海南霞迪药业有限公司 一种制备帕瑞昔布的方法
CN103172583A (zh) * 2013-03-07 2013-06-26 深圳市资福药业有限公司 一种制备帕瑞昔布的方法
CN104250232A (zh) * 2013-06-26 2014-12-31 四川唯拓生物医药有限公司 一种帕瑞昔布钠的制备方法
CN104418818B (zh) * 2013-09-04 2017-01-11 天津汉瑞药业有限公司 帕瑞昔布钠无水化合物
CN104447600B (zh) * 2013-09-22 2016-03-30 江苏奥赛康药业股份有限公司 一种帕瑞昔布钠化合物的制备方法及其中间体杂质、制备方法与应用
CN105801508B (zh) * 2014-12-30 2018-12-11 上海鼎雅药物化学科技有限公司 帕瑞昔布的制备方法
CN106146424A (zh) * 2015-03-23 2016-11-23 上海医药工业研究院 一种5-甲基-3,4-二苯基异噁唑的制备方法
CN106008385B (zh) * 2016-05-25 2018-10-30 浙江宏冠生物药业有限公司 一种帕瑞昔布钠的合成方法
CN108164521B (zh) * 2018-03-02 2020-11-13 成都新恒创药业有限公司 一种帕瑞昔布钠降解杂质及其制备、检测方法和应用
CN110790745A (zh) * 2019-11-12 2020-02-14 青岛科技大学 一种从废片中提取维他昔布的制备方法
CN111100084B (zh) * 2019-12-30 2022-12-06 山东罗欣药业集团恒欣药业有限公司 一种帕瑞昔布钠的制备方法
CN111153866A (zh) * 2020-01-19 2020-05-15 上海臣邦医药科技股份有限公司 帕瑞昔布钠双取代杂质及其制备方法和应用
CN114441666B (zh) * 2020-11-05 2024-02-27 成都百裕制药股份有限公司 一种4-(5-甲基-3-苯基-4-异恶唑)苯磺酰氯中杂质的检测方法
CN113149925A (zh) * 2021-03-23 2021-07-23 蚌埠丰原涂山制药有限公司 一种伐地昔布的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01250342A (ja) * 1988-03-31 1989-10-05 Agency Of Ind Science & Technol スルホン化合物の合成法
US5136043A (en) * 1989-06-17 1992-08-04 Hoechst Aktiengesellschaft Process for the preparation of aromatic sulfonyl chlorides
WO1996025405A1 (en) * 1995-02-13 1996-08-22 G.D. Searle & Co. Substituted isoxazoles for the treatment of inflammation
US5633272A (en) * 1995-02-13 1997-05-27 Talley; John J. Substituted isoxazoles for the treatment of inflammation
AP1009A (en) * 1996-04-12 2001-09-21 Searle & Co Substituted benzenesulfonamide derivatives as products of COX-2 inhibitors.
CA2287931A1 (en) * 1997-05-13 1998-11-19 Merck & Co., Inc. Process for synthesizing carbapenem intermediates
EP1023062B1 (en) * 1997-10-15 2002-12-18 Merck & Co., Inc. Antibacterial carbapenems, compositions and methods of treatment

Also Published As

Publication number Publication date
EP1438300A1 (en) 2004-07-21
RS34904A (en) 2007-04-10
BR0213027A (pt) 2004-10-05
RU2004109595A (ru) 2005-10-20
JP2005509608A (ja) 2005-04-14
HK1069578A1 (en) 2005-05-27
KR20040085135A (ko) 2004-10-07
IL161086A0 (en) 2004-08-31
CA2462297C (en) 2009-04-07
CN1308315C (zh) 2007-04-04
AU2008205429A1 (en) 2008-09-18
PL369676A1 (en) 2005-05-02
RU2284324C2 (ru) 2006-09-27
CA2462297A1 (en) 2003-04-10
US20030105334A1 (en) 2003-06-05
AU2008205429B2 (en) 2008-11-06
WO2003029230A1 (en) 2003-04-10
CN1578774A (zh) 2005-02-09
ZA200402472B (en) 2004-12-14
IL161086A (en) 2010-04-15
AU2002337804B2 (en) 2008-06-26

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