MXPA04001854A - Sistema de indan-1-ol polisubstituidos, metodo para la produccion y uso de los mismos como drogas. - Google Patents

Sistema de indan-1-ol polisubstituidos, metodo para la produccion y uso de los mismos como drogas.

Info

Publication number
MXPA04001854A
MXPA04001854A MXPA04001854A MXPA04001854A MXPA04001854A MX PA04001854 A MXPA04001854 A MX PA04001854A MX PA04001854 A MXPA04001854 A MX PA04001854A MX PA04001854 A MXPA04001854 A MX PA04001854A MX PA04001854 A MXPA04001854 A MX PA04001854A
Authority
MX
Mexico
Prior art keywords
systems
drugs
production
indan
polysubstituted
Prior art date
Application number
MXPA04001854A
Other languages
English (en)
Inventor
Bickel Martin
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of MXPA04001854A publication Critical patent/MXPA04001854A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/17—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/20—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La invencion se relaciona con sistemas indan-1-o1 polisubstituidos, las sales fisiologicamente. aceptables y derivados fisiologicamente de los mismos. La invencion se relaciona con los compuestos de la formula (I), en donde los grupos se definen como se indica, a las sales fisiologicamente aceptables y derivados fisiologicamente funcionales de los mismos, que son utiles, por ejemplo, como anorecticos. (ver formula).
MXPA04001854A 2001-08-31 2002-08-17 Sistema de indan-1-ol polisubstituidos, metodo para la produccion y uso de los mismos como drogas. MXPA04001854A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10142661A DE10142661B4 (de) 2001-08-31 2001-08-31 Mehrfach substituierte Indan-1-ol-Systeme und ihre Verwendung als Arzneimittel
PCT/EP2002/009201 WO2003020693A1 (de) 2001-08-31 2002-08-17 Mehrfach substituierte indan-1-ol-systeme, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
MXPA04001854A true MXPA04001854A (es) 2004-06-15

Family

ID=7697232

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04001854A MXPA04001854A (es) 2001-08-31 2002-08-17 Sistema de indan-1-ol polisubstituidos, metodo para la produccion y uso de los mismos como drogas.

Country Status (11)

Country Link
US (3) US6670401B2 (es)
EP (1) EP1423358B1 (es)
JP (1) JP4250077B2 (es)
AT (1) ATE476413T1 (es)
AU (1) AU2002329252B2 (es)
CA (1) CA2458520C (es)
DE (2) DE10142661B4 (es)
IL (1) IL160602A0 (es)
MX (1) MXPA04001854A (es)
PE (1) PE20030364A1 (es)
WO (1) WO2003020693A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10142659A1 (de) * 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von mehrfach substituierten Indan-1-ol. Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
DE10142663B4 (de) 2001-08-31 2004-08-19 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-ol-Systeme

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2201882B1 (es) * 1972-07-20 1975-10-31 Logeais Labor Jacques
GB1465794A (en) * 1974-05-17 1977-03-02 Wyeth John & Brother Ltd Thiourea derivatives
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
EP0009554B1 (de) * 1978-07-27 1983-04-27 Schering Aktiengesellschaft Indanyl-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE3103372A1 (de) * 1981-01-27 1982-09-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue indanyl-derivate, ihre herstellung und verwendung
ATE260241T1 (de) * 1995-12-06 2004-03-15 Venantius Ltd Indanverbindungen mit relaxierender wirkung auf die glatten muskeln und/oder mit mastzellen stabilisiernder und/oder entzuendungshemmender wirkung
CA2241567A1 (en) 1996-01-17 1997-07-24 Novo Nordisk A/S Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use
CA2468374C (en) 1996-08-30 2010-12-21 Novo-Nordisk A/S Glp-1 derivatives
ES2199366T3 (es) 1996-12-31 2004-02-16 Dr. Reddy's Laboratories Ltd. Compuestos heterociclicos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen y su uso en el tratamiento de diabetes y enfermedades relacionadas.
HUP0003999A3 (en) 1997-07-16 2003-03-28 Novo Nordisk As Fused 1,2,4-thiadiazine derivatives, their preparation, their use and pharmaceutical compositions containing them
FR2769312B1 (fr) * 1997-10-03 1999-12-03 Adir Nouveaux composes de l'indanol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2782515B1 (fr) * 1998-08-21 2000-09-22 Adir NOUVEAUX DERIVES DE L'INDANE-1-Ol, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
EP1078632A1 (en) 1999-08-16 2001-02-28 Sanofi-Synthelabo Use of monoamine oxydase inhibitors for the manufacture of drugs intended for the treatment of obesity
DE10142659A1 (de) * 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von mehrfach substituierten Indan-1-ol. Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
DE10142662B4 (de) * 2001-08-31 2004-07-08 Aventis Pharma Deutschland Gmbh Derivate von C2-substituierten Indan-1-ol-Systemen und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
CA2458520C (en) 2010-12-14
CA2458520A1 (en) 2003-03-13
ATE476413T1 (de) 2010-08-15
DE50214570D1 (de) 2010-09-16
DE10142661A1 (de) 2003-03-27
AU2002329252B2 (en) 2007-08-23
US20030105145A1 (en) 2003-06-05
US20040092489A1 (en) 2004-05-13
US6670401B2 (en) 2003-12-30
EP1423358B1 (de) 2010-08-04
DE10142661B4 (de) 2004-06-09
US20040092749A1 (en) 2004-05-13
WO2003020693A1 (de) 2003-03-13
PE20030364A1 (es) 2003-06-04
JP4250077B2 (ja) 2009-04-08
JP2005501901A (ja) 2005-01-20
EP1423358A1 (de) 2004-06-02
IL160602A0 (en) 2004-07-25

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