MXPA04000354A - Macromoleculas similares a estrella anfifilica para suministro de farmaco. - Google Patents

Macromoleculas similares a estrella anfifilica para suministro de farmaco.

Info

Publication number
MXPA04000354A
MXPA04000354A MXPA04000354A MXPA04000354A MXPA04000354A MX PA04000354 A MXPA04000354 A MX PA04000354A MX PA04000354 A MXPA04000354 A MX PA04000354A MX PA04000354 A MXPA04000354 A MX PA04000354A MX PA04000354 A MXPA04000354 A MX PA04000354A
Authority
MX
Mexico
Prior art keywords
macromolecules
drug delivery
amphiphilic star
amphiphilic
star
Prior art date
Application number
MXPA04000354A
Other languages
English (en)
Inventor
Tian Lu
Original Assignee
Univ Rutgers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rutgers filed Critical Univ Rutgers
Publication of MXPA04000354A publication Critical patent/MXPA04000354A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

La presente invencion proporciona compuestos polimericos que pueden formar micelas en soluciones. Estos compuestos tienen un nucleo hidrofobico, que se acopla a una pluralidad de porciones hidrofilicas.
MXPA04000354A 2001-07-12 2002-07-12 Macromoleculas similares a estrella anfifilica para suministro de farmaco. MXPA04000354A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30496501P 2001-07-12 2001-07-12
US33331001P 2001-11-23 2001-11-23
PCT/US2002/021923 WO2003005959A2 (en) 2001-07-12 2002-07-12 Amphiphilic star-like macromolecules for drug delivery

Publications (1)

Publication Number Publication Date
MXPA04000354A true MXPA04000354A (es) 2004-07-23

Family

ID=26974329

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04000354A MXPA04000354A (es) 2001-07-12 2002-07-12 Macromoleculas similares a estrella anfifilica para suministro de farmaco.

Country Status (7)

Country Link
US (1) US7262221B2 (es)
EP (1) EP1414784A2 (es)
JP (1) JP2005509593A (es)
KR (1) KR20040029359A (es)
CA (1) CA2453216A1 (es)
MX (1) MXPA04000354A (es)
WO (1) WO2003005959A2 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
CA2488121C (en) 2002-06-07 2012-07-24 Rutgers, The State University Micelle assemblies
WO2005074887A2 (en) * 2004-01-30 2005-08-18 Rutgers, The State University Amphiphilic star-like or scorpion-like macromolecules, various compositions and uses thereof
US20050180922A1 (en) * 2004-02-12 2005-08-18 Discher Dennis E. Block co-polymer worm micelles and methods of use therefor
WO2005118877A2 (en) * 2004-06-02 2005-12-15 Vicus Bioscience, Llc Producing, cataloging and classifying sequence tags
US20120269886A1 (en) 2004-12-22 2012-10-25 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
HUE048419T2 (hu) 2004-12-22 2020-08-28 Nitto Denko Corp Gyógyszerhordozó és kit gyógyszerhordozó kit fibrózis gátlására
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
TWI407971B (zh) 2007-03-30 2013-09-11 Nitto Denko Corp Cancer cells and tumor-related fibroblasts
US20090069740A1 (en) * 2007-09-07 2009-03-12 Polyplus Battery Company Protected donor electrodes for electro-transport drug delivery
EP2207570A2 (en) 2007-09-14 2010-07-21 Nitto Denko Corporation Drug carriers
US20110008396A1 (en) * 2007-09-20 2011-01-13 Rutgers, The Sate University Of New Jersey Compositions and methods for treating cardiovascular conditions
WO2010118362A1 (en) 2009-04-09 2010-10-14 The Regents Of The University Of Colorado, A Body Corporate Methods and compositions for inducing physiological hypertrophy
US8846850B2 (en) 2011-02-22 2014-09-30 Rutgers, The State University Of New Jersey Amphiphilic macromolecules for nucleic acid delivery
EP2714023A4 (en) * 2011-05-23 2014-12-24 Univ Massachusetts RETICULATED POLYMER NANO-ASSEMBLIES AND USES THEREOF
EP2861558B1 (en) 2012-06-15 2017-01-18 Rutgers, The State University of New Jersey Macromolecules for treating atherosclerosis
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
WO2014194055A1 (en) 2013-05-29 2014-12-04 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
US9399044B2 (en) 2014-05-28 2016-07-26 International Business Machines Corporation Antimicrobial cationic polyamines
US10023521B2 (en) 2014-06-13 2018-07-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
WO2015195563A1 (en) 2014-06-16 2015-12-23 Rutgers, The State University Of New Jersey Antibacterial agents
US9630905B2 (en) 2014-09-08 2017-04-25 Rutgers, The State University Of New Jersey Amphiphilic macromolecules and methods of use thereof
WO2016164898A1 (en) 2015-04-10 2016-10-13 Rutgers, The State University Of New Jersey Kojic acid polymers
WO2017165836A1 (en) 2016-03-24 2017-09-28 Rutgers, The State University Of New Jersey Antibacterial agents
WO2018027227A1 (en) 2016-08-05 2018-02-08 Rutgers, The State University Of New Jersey Thermocleavable friction modifiers and methods thereof
WO2023146255A1 (ko) * 2022-01-25 2023-08-03 주식회사 메디치바이오 알부민과 결합하는 소수성 구조를 함유한 펩타이드 전달체

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3235974A1 (de) 1981-11-24 1983-06-01 Volkmar Dipl.-Ing. Merkel (FH), 8520 Erlangen Vorrichtung zur entfernung bzw. zur aufweitung von engstellen in koerperfluessigkeit fuehrenden gefaessen
US4597961A (en) 1985-01-23 1986-07-01 Etscorn Frank T Transcutaneous application of nicotine
DE3634016A1 (de) 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung
DE3743946A1 (de) 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung
US6007845A (en) 1994-07-22 1999-12-28 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
US5830986A (en) 1996-10-28 1998-11-03 Massachusetts Institute Of Technology Methods for the synthesis of functionalizable poly(ethylene oxide) star macromolecules
FR2783418B1 (fr) * 1998-09-17 2000-11-10 Oreal Composition anti-rides comprenant une association de polymeres tenseurs d'origine synthetique et/ou naturelle et de polyesters dendritiques

Also Published As

Publication number Publication date
EP1414784A2 (en) 2004-05-06
KR20040029359A (ko) 2004-04-06
US20040198641A1 (en) 2004-10-07
WO2003005959A3 (en) 2003-10-09
US7262221B2 (en) 2007-08-28
JP2005509593A (ja) 2005-04-14
WO2003005959A2 (en) 2003-01-23
CA2453216A1 (en) 2003-01-23

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