MXPA03003994A - Composiciones de metformina de liberacion controlada. - Google Patents
Composiciones de metformina de liberacion controlada.Info
- Publication number
- MXPA03003994A MXPA03003994A MXPA03003994A MXPA03003994A MXPA03003994A MX PA03003994 A MXPA03003994 A MX PA03003994A MX PA03003994 A MXPA03003994 A MX PA03003994A MX PA03003994 A MXPA03003994 A MX PA03003994A MX PA03003994 A MXPA03003994 A MX PA03003994A
- Authority
- MX
- Mexico
- Prior art keywords
- drug
- controlled release
- dosage form
- day basis
- release metformin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Abstract
Una composicion y metodos para esta para tratar pacientes con diabetes melitus no dependiente de la insulina (NIDDM), administrando una forma de dosis solida oral de liberacion controlada, que contiene preferiblemente un farmaco biguanida como metformina, una vez al dia. La forma de dosis proporciona un tiempo medio hasta la concentracion maxima en plasma ( ) del farmaco que ocurre a entre 5.5 y 7.5 horas despues de la administracion oral una vez al dia, a pacientes humanos. Preferiblemente, la dosis del farmaco se administra a la cena a un paciente en estado post-prandial.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/705,625 US6790459B1 (en) | 2000-11-03 | 2000-11-03 | Methods for treating diabetes via administration of controlled release metformin |
US09/705,630 US6866866B1 (en) | 2000-11-03 | 2000-11-03 | Controlled release metformin compositions |
PCT/US2001/048306 WO2002036100A1 (en) | 2000-11-03 | 2001-10-30 | Controlled release metformin compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03003994A true MXPA03003994A (es) | 2004-09-10 |
Family
ID=27107545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03003994A MXPA03003994A (es) | 2000-11-03 | 2001-10-30 | Composiciones de metformina de liberacion controlada. |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP1723948A1 (es) |
JP (1) | JP2004531463A (es) |
KR (1) | KR20030061392A (es) |
AU (1) | AU2002230830A1 (es) |
BR (1) | BR0115390A (es) |
CA (1) | CA2427195C (es) |
MX (1) | MXPA03003994A (es) |
NZ (1) | NZ525559A (es) |
WO (1) | WO2002036100A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8323692B2 (en) * | 2002-02-21 | 2012-12-04 | Valeant International Bermuda | Controlled release dosage forms |
AU2002356419A1 (en) | 2002-06-17 | 2003-12-31 | Themis Laboratories Private Limited | Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them |
EP1510208A1 (en) | 2003-08-22 | 2005-03-02 | Fournier Laboratories Ireland Limited | Pharmaceutical composition comprising a combination of metformin and statin |
EP1746993A4 (en) * | 2004-04-29 | 2007-08-29 | Andrx Labs Llc | METFORMIN COMPOSITIONS WITH CONTROLLED RELEASE |
EP1752147A4 (en) * | 2004-06-04 | 2007-10-31 | Kowa Co | MEDICINE FOR THE PREVENTION OR TREATMENT OF DIABETES |
KR20070086007A (ko) * | 2004-12-13 | 2007-08-27 | 다이이찌 산쿄 가부시키가이샤 | 당뇨병의 치료를 위한 의약 조성물 |
UY29445A1 (es) * | 2005-03-30 | 2006-10-02 | Generex Pharm Inc | Composiciones para la transmisión transmucosa oral de la metformina |
KR100780553B1 (ko) * | 2005-08-18 | 2007-11-29 | 한올제약주식회사 | 메트포르민 서방정 및 그의 제조방법 |
KR101362729B1 (ko) | 2007-05-08 | 2014-02-12 | 삼성디스플레이 주식회사 | 광학 시트, 이의 제조 방법 및 이를 갖는 표시 장치 |
WO2010026467A2 (en) | 2008-09-04 | 2010-03-11 | Torrent Pharmaceuticals Ltd. | Controlled release dosage form of high solubility active ingredient |
KR101597004B1 (ko) | 2013-07-25 | 2016-02-23 | 씨제이헬스케어 주식회사 | 서방형 메트포르민과 속방형 HMG-CoA 환원효소 억제제를 포함하는 복합제제 |
CN106727407B (zh) * | 2017-01-04 | 2018-01-19 | 北京汇诚瑞祥医药技术有限公司 | 一种二甲双胍控释制剂及其制备方法 |
KR20190036370A (ko) | 2017-09-27 | 2019-04-04 | 서원대학교산학협력단 | 약물의 서방성 제형을 위한 약물전달체 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US411210A (en) | 1889-09-17 | Water-wheel | ||
US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
FR2243684B1 (es) | 1973-09-19 | 1977-01-28 | Semb | |
US4080472A (en) | 1974-03-22 | 1978-03-21 | Societe D'etudes Et D'exploitation De Marques Et Brevets S.E.M.S. | Metformin 2-(p-chlorophenoxy)-2-methylpropionate |
GB1478759A (en) | 1974-11-18 | 1977-07-06 | Alza Corp | Process for forming outlet passageways in pills using a laser |
US3952741A (en) | 1975-01-09 | 1976-04-27 | Bend Research Inc. | Controlled release delivery system by an osmotic bursting mechanism |
US4034758A (en) | 1975-09-08 | 1977-07-12 | Alza Corporation | Osmotic therapeutic system for administering medicament |
US4036228A (en) | 1975-09-11 | 1977-07-19 | Alza Corporation | Osmotic dispenser with gas generating means |
US4077407A (en) | 1975-11-24 | 1978-03-07 | Alza Corporation | Osmotic devices having composite walls |
US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
US4063064A (en) | 1976-02-23 | 1977-12-13 | Coherent Radiation | Apparatus for tracking moving workpiece by a laser beam |
US4522625A (en) | 1982-09-29 | 1985-06-11 | Alza Corporation | Drug dispenser comprising wall formed of semipermeable member and enteric member |
US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
US4587117A (en) | 1983-06-06 | 1986-05-06 | Alza Corporation | Medical device for delivering drug to pH environments greater than 3.5 |
US4851229A (en) | 1983-12-01 | 1989-07-25 | Alza Corporation | Composition comprising a therapeutic agent and a modulating agent |
US4777049A (en) | 1983-12-01 | 1988-10-11 | Alza Corporation | Constant release system with pulsed release |
US4892739A (en) | 1988-04-25 | 1990-01-09 | Ciba-Geigy Corporation | Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties |
US5071607A (en) | 1990-01-31 | 1991-12-10 | Alza Corporatino | Method and apparatus for forming a hole in a drug dispensing device |
US5178866A (en) | 1990-03-23 | 1993-01-12 | Alza Corporation | Dosage form for delivering drug to the intestine |
US5178867A (en) | 1991-08-19 | 1993-01-12 | Alza Corporation | Dosage form for delivering drug in short-time period |
DE4432757A1 (de) | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung |
AP1224A (en) | 1998-03-19 | 2003-11-14 | Bristol Myers Squibb Co | Biphasic controlled release delivery system for high solubility pharmaceuticals and method. |
US6099859A (en) | 1998-03-20 | 2000-08-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
US6099862A (en) * | 1998-08-31 | 2000-08-08 | Andrx Corporation | Oral dosage form for the controlled release of a biguanide and sulfonylurea |
EP1813273A1 (en) * | 1998-11-12 | 2007-08-01 | Smithkline Beecham Plc | Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent |
-
2001
- 2001-10-30 EP EP06013969A patent/EP1723948A1/en not_active Ceased
- 2001-10-30 KR KR10-2003-7006157A patent/KR20030061392A/ko not_active Application Discontinuation
- 2001-10-30 AU AU2002230830A patent/AU2002230830A1/en not_active Abandoned
- 2001-10-30 EP EP01991078A patent/EP1335708A4/en not_active Ceased
- 2001-10-30 BR BR0115390-0A patent/BR0115390A/pt not_active Application Discontinuation
- 2001-10-30 CA CA002427195A patent/CA2427195C/en not_active Expired - Lifetime
- 2001-10-30 MX MXPA03003994A patent/MXPA03003994A/es active IP Right Grant
- 2001-10-30 JP JP2002538912A patent/JP2004531463A/ja active Pending
- 2001-10-30 NZ NZ525559A patent/NZ525559A/en not_active IP Right Cessation
- 2001-10-30 WO PCT/US2001/048306 patent/WO2002036100A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2427195A1 (en) | 2002-05-10 |
WO2002036100A1 (en) | 2002-05-10 |
WO2002036100A9 (en) | 2003-07-24 |
NZ525559A (en) | 2005-07-29 |
JP2004531463A (ja) | 2004-10-14 |
EP1335708A1 (en) | 2003-08-20 |
AU2002230830A1 (en) | 2002-05-15 |
CA2427195C (en) | 2009-10-06 |
KR20030061392A (ko) | 2003-07-18 |
EP1335708A4 (en) | 2005-07-13 |
BR0115390A (pt) | 2004-02-25 |
EP1723948A1 (en) | 2006-11-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or rights | ||
FG | Grant or registration |