EP1335708A4 - Controlled release metformin compositions - Google Patents

Controlled release metformin compositions

Info

Publication number
EP1335708A4
EP1335708A4 EP01991078A EP01991078A EP1335708A4 EP 1335708 A4 EP1335708 A4 EP 1335708A4 EP 01991078 A EP01991078 A EP 01991078A EP 01991078 A EP01991078 A EP 01991078A EP 1335708 A4 EP1335708 A4 EP 1335708A4
Authority
EP
European Patent Office
Prior art keywords
controlled release
release metformin
metformin compositions
compositions
controlled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP01991078A
Other languages
German (de)
French (fr)
Other versions
EP1335708A1 (en
Inventor
Chen Chih-Ming
Cheng Xiu-Xiu
Steve Jan
Joseph Chou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Andrx Labs LLC
Original Assignee
Andrx Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US705625 priority Critical
Priority to US09/705,625 priority patent/US6790459B1/en
Priority to US09/705,630 priority patent/US6866866B1/en
Priority to US705630 priority
Application filed by Andrx Corp filed Critical Andrx Corp
Priority to PCT/US2001/048306 priority patent/WO2002036100A1/en
Publication of EP1335708A1 publication Critical patent/EP1335708A1/en
Publication of EP1335708A4 publication Critical patent/EP1335708A4/en
Application status is Ceased legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
EP01991078A 2000-11-03 2001-10-30 Controlled release metformin compositions Ceased EP1335708A4 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US705625 1996-08-30
US09/705,625 US6790459B1 (en) 2000-11-03 2000-11-03 Methods for treating diabetes via administration of controlled release metformin
US09/705,630 US6866866B1 (en) 2000-11-03 2000-11-03 Controlled release metformin compositions
US705630 2000-11-03
PCT/US2001/048306 WO2002036100A1 (en) 2000-11-03 2001-10-30 Controlled release metformin compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06013969A EP1723948A1 (en) 2000-11-03 2001-10-30 Controlled release compositions of biguanide with less side effects and treatment regimen thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP06013969A Division EP1723948A1 (en) 2000-11-03 2001-10-30 Controlled release compositions of biguanide with less side effects and treatment regimen thereof

Publications (2)

Publication Number Publication Date
EP1335708A1 EP1335708A1 (en) 2003-08-20
EP1335708A4 true EP1335708A4 (en) 2005-07-13

Family

ID=27107545

Family Applications (2)

Application Number Title Priority Date Filing Date
EP01991078A Ceased EP1335708A4 (en) 2000-11-03 2001-10-30 Controlled release metformin compositions
EP06013969A Ceased EP1723948A1 (en) 2000-11-03 2001-10-30 Controlled release compositions of biguanide with less side effects and treatment regimen thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP06013969A Ceased EP1723948A1 (en) 2000-11-03 2001-10-30 Controlled release compositions of biguanide with less side effects and treatment regimen thereof

Country Status (9)

Country Link
EP (2) EP1335708A4 (en)
JP (1) JP2004531463A (en)
KR (1) KR20030061392A (en)
AU (1) AU3083002A (en)
BR (1) BR0115390A (en)
CA (1) CA2427195C (en)
MX (1) MXPA03003994A (en)
NZ (1) NZ525559A (en)
WO (1) WO2002036100A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8323692B2 (en) * 2002-02-21 2012-12-04 Valeant International Bermuda Controlled release dosage forms
EP1515701B1 (en) 2002-06-17 2014-09-17 Inventia Healthcare Private Limited Process for the manufacture of multilayer tablet compositions comprising thiazolidinedione and biguanide
EP1510208A1 (en) 2003-08-22 2005-03-02 Fournier Laboratories Ireland Limited Pharmaceutical composition comprising a combination of metformin and statin
EP1746993A4 (en) * 2004-04-29 2007-08-29 Andrx Labs Llc Controlled release metformin compositions
WO2005117855A1 (en) * 2004-06-04 2005-12-15 Kowa Company., Ltd. Drug for prevention or treatment of diabetes
BRPI0519006A2 (en) * 2004-12-13 2008-12-23 Daiichi Sankyo Co Ltd use of an FBPase inhibitor, a pharmaceutical kit composiÇço, preparaÇço use of a biguanide and FBPase inhibitor, therapeutic agent for diabetes mellitus, and therapeutic agents combinaÇço
PE12452006A1 (en) * 2005-03-30 2007-01-06 Generex Pharm Inc Compositions for oral transmucosal metformin transmission
KR100780553B1 (en) * 2005-08-18 2007-11-29 한올제약주식회사 Pharmaceutical compositions and formulations of Metformin extended release tablets and its preparing method
KR101362729B1 (en) 2007-05-08 2014-02-12 삼성디스플레이 주식회사 Optical sheet, method of manufacturing the same and display apparatus having the same
WO2010026467A2 (en) 2008-09-04 2010-03-11 Torrent Pharmaceuticals Ltd. Controlled release dosage form of high solubility active ingredient
KR101597004B1 (en) 2013-07-25 2016-02-23 씨제이헬스케어 주식회사 Pharmaceutical combination comprising sustained-release type metformin and immediate-release type HMG-CoA reductase inhibitor
CN106727407B (en) * 2017-01-04 2018-01-19 北京汇诚瑞祥医药技术有限公司 One kind of controlled release formulation of metformin and its preparation method
KR20190036370A (en) 2017-09-27 2019-04-04 서원대학교산학협력단 Drug Delivery System for Sustained Release Formaulation of Drugs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012097A1 (en) * 1998-08-31 2000-03-09 Andrx Pharmaceuticals, Inc. Controlled release tablet comprising a hypoglycemic drug and an antihyperglycemic drug

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US411210A (en) 1889-09-17 Water-wheel
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
FR2243684B1 (en) 1973-09-19 1977-01-28 Semb
US4080472A (en) 1974-03-22 1978-03-21 Societe D'etudes Et D'exploitation De Marques Et Brevets S.E.M.S. Metformin 2-(p-chlorophenoxy)-2-methylpropionate
US4063064A (en) 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
GB1478759A (en) 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US3952741B1 (en) 1975-01-09 1983-01-18
US4034758A (en) 1975-09-08 1977-07-12 Alza Corporation Osmotic therapeutic system for administering medicament
US4036228A (en) 1975-09-11 1977-07-19 Alza Corporation Osmotic dispenser with gas generating means
US4077407A (en) 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4522625A (en) 1982-09-29 1985-06-11 Alza Corporation Drug dispenser comprising wall formed of semipermeable member and enteric member
US4783337A (en) 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US4587117A (en) 1983-06-06 1986-05-06 Alza Corporation Medical device for delivering drug to pH environments greater than 3.5
US4777049A (en) 1983-12-01 1988-10-11 Alza Corporation Constant release system with pulsed release
US4851229A (en) 1983-12-01 1989-07-25 Alza Corporation Composition comprising a therapeutic agent and a modulating agent
US4892739A (en) 1988-04-25 1990-01-09 Ciba-Geigy Corporation Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties
US5071607A (en) 1990-01-31 1991-12-10 Alza Corporatino Method and apparatus for forming a hole in a drug dispensing device
US5178866A (en) 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
US5178867A (en) 1991-08-19 1993-01-12 Alza Corporation Dosage form for delivering drug in short-time period
DE4432757A1 (en) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmaceutical composition comprising metformin and methods of their production
BR9908911A (en) 1998-03-19 2001-10-02 Squibb Bristol Myers Co biphasic system and distribution process by controlled release of high solubility pharmaceutical substances
US6099859A (en) 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
YU37301A (en) * 1998-11-12 2005-06-10 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012097A1 (en) * 1998-08-31 2000-03-09 Andrx Pharmaceuticals, Inc. Controlled release tablet comprising a hypoglycemic drug and an antihyperglycemic drug

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0236100A1 *

Also Published As

Publication number Publication date
CA2427195A1 (en) 2002-05-10
AU3083002A (en) 2002-05-15
EP1335708A1 (en) 2003-08-20
BR0115390A (en) 2004-02-25
EP1723948A1 (en) 2006-11-22
JP2004531463A (en) 2004-10-14
WO2002036100A1 (en) 2002-05-10
MXPA03003994A (en) 2004-09-10
CA2427195C (en) 2009-10-06
KR20030061392A (en) 2003-07-18
WO2002036100A9 (en) 2003-07-24
NZ525559A (en) 2005-07-29

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Legal Events

Date Code Title Description
AX Request for extension of the european patent to

Countries concerned: ALLTLVMKROSI

17P Request for examination filed

Effective date: 20030505

AK Designated contracting states:

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

A4 Despatch of supplementary search report

Effective date: 20050601

RAP1 Transfer of rights of an ep published application

Owner name: ANDRX LABS, LLC

17Q First examination report

Effective date: 20060104

REG Reference to a national code

Ref country code: DE

Ref legal event code: R003

18R Refused

Effective date: 20121213