MXPA03001391A - Uso de anticuerpos contra complejos especificos mhc-peptidos. - Google Patents
Uso de anticuerpos contra complejos especificos mhc-peptidos.Info
- Publication number
- MXPA03001391A MXPA03001391A MXPA03001391A MXPA03001391A MXPA03001391A MX PA03001391 A MXPA03001391 A MX PA03001391A MX PA03001391 A MXPA03001391 A MX PA03001391A MX PA03001391 A MXPA03001391 A MX PA03001391A MX PA03001391 A MXPA03001391 A MX PA03001391A
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies against
- specific mhc
- peptide complexes
- against specific
- mhc
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rehabilitation Therapy (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La invencion describe un metodo para diagnosticar la actividad de enfermedad autoinmune mediante la deteccion de la presencia de un complejo autoinmune especifico de MHC-peptido en un paciente que sufre de una enfermedad autoinmune. El complejo de MHC-peptido se asocia con artritis reumatoide. Los anticuerpos monoclonales a utilizarse para este metodo tambien se describen. Los anticuerpos tambien pueden utilizarse para propositos terapeuticos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00202844 | 2000-08-14 | ||
PCT/EP2001/009136 WO2002014870A2 (en) | 2000-08-14 | 2001-08-08 | Use of antibodies against specific mhc-peptide complexes |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03001391A true MXPA03001391A (es) | 2004-05-04 |
Family
ID=8171913
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03001391A MXPA03001391A (es) | 2000-08-14 | 2001-08-08 | Uso de anticuerpos contra complejos especificos mhc-peptidos. |
Country Status (14)
Country | Link |
---|---|
US (1) | US7320873B2 (es) |
EP (1) | EP1319184B1 (es) |
JP (1) | JP2004506901A (es) |
CN (1) | CN1305906C (es) |
AR (1) | AR033832A1 (es) |
AT (1) | ATE368225T1 (es) |
AU (2) | AU9373501A (es) |
BR (1) | BR0113213A (es) |
CA (1) | CA2415353A1 (es) |
DE (1) | DE60129572T2 (es) |
ES (1) | ES2290171T3 (es) |
IL (2) | IL154000A0 (es) |
MX (1) | MXPA03001391A (es) |
WO (1) | WO2002014870A2 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA04000769A (es) | 2001-07-24 | 2005-09-21 | Zhu Zhou | Metodos, composiciones y equipos relacionados a quitinasas y moleculas similares a la quitinasa y enfermedad inflamatoria. |
CA2567814C (en) * | 2004-05-27 | 2013-07-23 | Jon A. Weidanz | Antibodies as t cell receptor mimics, methods of production and uses thereof |
WO2007030451A2 (en) * | 2005-09-07 | 2007-03-15 | Receptor Logic, Ltd. | Antibodies as t cell receptor mimics, methods of production and uses thereof |
WO2008089494A2 (en) * | 2007-01-19 | 2008-07-24 | Kai Pharmaceuticals, Inc. | Methods of use of epsilon inhibitor compounds for the attenuation of pain |
WO2009151487A1 (en) * | 2008-06-13 | 2009-12-17 | Receptor Logic, Inc. | Methods of assaying vaccine potency |
US8673300B2 (en) | 2009-06-04 | 2014-03-18 | The Regents Of The University Of Colorado, A Body Corporate | Therapeutic compositions and methods for the prevention of autoimmune diseases |
CN103068396B (zh) * | 2010-03-02 | 2016-07-06 | 诺沃姆德治疗公司 | 抑制c5和备解素相互作用的抗-备解素抗体在制备抑制交替途径活化的药剂中的用途 |
US20130189284A1 (en) * | 2010-07-15 | 2013-07-25 | Technion Research & Development Foundation Ltd. | Antibodies with t-cell receptor like specificity towards native complexes of mhc class ii and diabetes-associated autoantigenic peptides |
BR112013000985A2 (pt) | 2010-07-15 | 2017-09-05 | Technion Res & Dev Foundation | Entidades isoladas de alta afinidade com especificidade semelhante à do receptor de célula t em relação a complexos nativos de mhc classe ii e peptídeos autoantigênicos de descarboxilase do ácido glutâmico (gad) |
US20130302329A1 (en) * | 2010-09-21 | 2013-11-14 | Trustees Of Boston University | Diagnostic tests for immune reactivity with human endothelial cell growth factor |
MY159058A (en) | 2011-02-25 | 2016-12-15 | Merck Sharp & Dohme | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agent |
US9629848B2 (en) | 2011-05-26 | 2017-04-25 | The Regents Of The University Of Colorado, A Body Corporate | Compounds that modulate autoimmunity and methods of using the same |
CN104870474B (zh) | 2012-10-04 | 2019-03-12 | 诺沃姆德治疗公司 | 用于治疗溶血性疾病的旁路途径特异性抗体 |
AP2016009586A0 (en) | 2014-05-29 | 2016-11-30 | Macrogenics Inc | Tri-specific binding molecules and methods of use thereof |
EP3247384B1 (en) | 2015-01-14 | 2023-10-04 | The Regents of the University of Colorado, a body corporate | In vitro method of diagnosis of type 1 diabetes with insulin mimotopes |
AU2017236977B2 (en) | 2016-03-24 | 2022-05-26 | Immunomolecular Therapeutics, Inc. | Methods of treating autoimmune disease |
AU2018224094A1 (en) | 2017-02-24 | 2019-09-19 | Macrogenics, Inc. | Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof |
US11052060B2 (en) | 2018-02-12 | 2021-07-06 | The Regents Of The University Of Colorado, A Body Corporate | Compounds and methods for treating autoimmunity |
US11013707B2 (en) | 2018-03-23 | 2021-05-25 | The Regents Of The University Of Colorado, A Body Corporate | Administration of oral methyldopa |
CN111423504B (zh) * | 2020-04-17 | 2021-03-26 | 安徽高安生物医学科技有限公司 | 黑色素瘤特异性抗原肽、肽复合物以及人工抗原呈递细胞 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE153695T1 (de) | 1990-11-26 | 1997-06-15 | Akzo Nobel Nv | Verfahren zur herstellung von antikörpern |
CA2164498C (en) * | 1993-07-09 | 2007-09-11 | Paul A. Price | Assay for ykl-40 as a marker for degradation of mammalian connective tissue matrices |
WO1995002188A1 (en) * | 1993-07-12 | 1995-01-19 | The Regents Of The University Of California | Assay for ykl-40 as a marker for degradation of mammalian connective tissue matrices |
WO1998012221A1 (de) * | 1996-09-18 | 1998-03-26 | Gerhild Wildner | Peptide als diagnostikum und therapeutikum für autoimmunerkrankungen |
IL122233A (en) | 1996-12-06 | 2001-04-30 | Akzo Nobel Nv | Method of generating monoclonal antibodies to cell wall and pharmaceutical preparations and diagnostic agents containing them |
-
2001
- 2001-08-08 AU AU9373501A patent/AU9373501A/xx active Pending
- 2001-08-08 AU AU2001293735A patent/AU2001293735B2/en not_active Ceased
- 2001-08-08 BR BR0113213-0A patent/BR0113213A/pt not_active IP Right Cessation
- 2001-08-08 IL IL15400001A patent/IL154000A0/xx unknown
- 2001-08-08 ES ES01974130T patent/ES2290171T3/es not_active Expired - Lifetime
- 2001-08-08 CN CNB018141935A patent/CN1305906C/zh not_active Expired - Fee Related
- 2001-08-08 WO PCT/EP2001/009136 patent/WO2002014870A2/en active IP Right Grant
- 2001-08-08 EP EP01974130A patent/EP1319184B1/en not_active Expired - Lifetime
- 2001-08-08 DE DE60129572T patent/DE60129572T2/de not_active Expired - Fee Related
- 2001-08-08 US US10/344,872 patent/US7320873B2/en not_active Expired - Fee Related
- 2001-08-08 MX MXPA03001391A patent/MXPA03001391A/es active IP Right Grant
- 2001-08-08 AT AT01974130T patent/ATE368225T1/de not_active IP Right Cessation
- 2001-08-08 JP JP2002519948A patent/JP2004506901A/ja not_active Withdrawn
- 2001-08-08 CA CA002415353A patent/CA2415353A1/en not_active Abandoned
- 2001-08-13 AR ARP010103870A patent/AR033832A1/es active IP Right Grant
-
2003
- 2003-01-16 IL IL154000A patent/IL154000A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE368225T1 (de) | 2007-08-15 |
AU2001293735B2 (en) | 2006-05-25 |
CN1447919A (zh) | 2003-10-08 |
JP2004506901A (ja) | 2004-03-04 |
US7320873B2 (en) | 2008-01-22 |
WO2002014870A3 (en) | 2002-08-15 |
AU9373501A (en) | 2002-02-25 |
DE60129572T2 (de) | 2008-04-17 |
EP1319184A2 (en) | 2003-06-18 |
IL154000A0 (en) | 2003-07-31 |
IL154000A (en) | 2010-02-17 |
CA2415353A1 (en) | 2002-02-21 |
US20040137514A1 (en) | 2004-07-15 |
EP1319184B1 (en) | 2007-07-25 |
ES2290171T3 (es) | 2008-02-16 |
CN1305906C (zh) | 2007-03-21 |
WO2002014870A2 (en) | 2002-02-21 |
AR033832A1 (es) | 2004-01-07 |
BR0113213A (pt) | 2003-07-08 |
DE60129572D1 (de) | 2007-09-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or rights | ||
FG | Grant or registration |