MXPA02011017A - Analisis para la funcion de la plaqueta y reactivo para el mismo. - Google Patents
Analisis para la funcion de la plaqueta y reactivo para el mismo.Info
- Publication number
- MXPA02011017A MXPA02011017A MXPA02011017A MXPA02011017A MXPA02011017A MX PA02011017 A MXPA02011017 A MX PA02011017A MX PA02011017 A MXPA02011017 A MX PA02011017A MX PA02011017 A MXPA02011017 A MX PA02011017A MX PA02011017 A MXPA02011017 A MX PA02011017A
- Authority
- MX
- Mexico
- Prior art keywords
- platelet function
- ligand
- reagent
- function assay
- assay
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Se proporciona un reactivo de analisis para la funcion de la plaqueta para realizar un analisis para la funcion de la plaqueta, en donde el reactivo contiene una mezcla de particulas magneticas y no magneticas, en donde las particulas magneticas han unido a una superficie exterior de las mismas una cantidad de un primer ligando que tiene una afinidad para interaccion directa con receptores GP-lb en plaquetas sanguineas y en donde las particulas no magneticas han unido a una superficie exterior de las mismas una cantidad de un segundo ligando que tiene una afinidad para interaccion directa con receptores GP-lb en plaquetas sanguineas, de manera que tal interaccion de cualquiera de los ligandos, primero y segundo, con el receptor de plaqueta GP-lb activara dichas plaquetas sanguineas hacia la agregacion, en donde el primer ligando y el segundo ligando pueden ser el mismo o diferente, y el analisis que utiliza tal reactivo, para proporcionar una valoracion del punto de cuidado confiable, rapida, de la funcion de la plaqueta.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20263800P | 2000-05-09 | 2000-05-09 | |
| PCT/US2001/011760 WO2001086248A2 (en) | 2000-05-09 | 2001-05-09 | Platelet function assay and reagent therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02011017A true MXPA02011017A (es) | 2004-08-19 |
Family
ID=22750704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02011017A MXPA02011017A (es) | 2000-05-09 | 2001-05-09 | Analisis para la funcion de la plaqueta y reactivo para el mismo. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1280931A4 (es) |
| JP (1) | JP2003532891A (es) |
| KR (1) | KR20030014219A (es) |
| AU (1) | AU2001261020A1 (es) |
| BR (1) | BR0110735A (es) |
| CA (1) | CA2408850A1 (es) |
| MX (1) | MXPA02011017A (es) |
| NO (1) | NO20025300L (es) |
| WO (1) | WO2001086248A2 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6680177B2 (en) * | 2001-12-07 | 2004-01-20 | Cardiovascular Diagnostics, Inc. | Low molecular weight heparin assay, system and reagent therefor |
| JP4078247B2 (ja) | 2003-05-02 | 2008-04-23 | キヤノン株式会社 | 磁性体−生体物質複合体型構造体、磁性体に対して結合能を有するアミノ酸配列を有するペプチド断片及びその遺伝子、ならびに磁性体−生体物質複合体型構造体の製造方法 |
| WO2011135397A1 (en) * | 2010-04-29 | 2011-11-03 | University Of Calcutta | Antiplatelet agent and methods of using the same |
| KR101276179B1 (ko) * | 2011-08-08 | 2013-06-18 | 고려대학교 산학협력단 | 혈소판 복합기능 검사 장치 및 방법, 이에 구비되는 미세교반칩 |
| US8772040B2 (en) | 2012-08-31 | 2014-07-08 | Korea University Research And Business Foundation | Apparatus and method of platelet multi-function analysis, and micro stirring chip |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5110727A (en) * | 1987-04-03 | 1992-05-05 | Cardiovascular Diagnostics, Inc. | Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles |
| US4849340A (en) * | 1987-04-03 | 1989-07-18 | Cardiovascular Diagnostics, Inc. | Reaction system element and method for performing prothrombin time assay |
| TW221493B (es) * | 1990-07-10 | 1994-03-01 | Cardiovascular Diagnostics Inc | |
| US5616311A (en) * | 1991-01-15 | 1997-04-01 | Hemosphere, Inc. | Non-crosslinked protein particles for therapeutic and diagnostic use |
| US5446132A (en) * | 1992-10-01 | 1995-08-29 | The General Hospital Corporation | Thrombin-activated platelet protein-2 (TAPP-2) |
| US5427913A (en) * | 1992-12-03 | 1995-06-27 | Alberta Cancer Board | Methods for determining platelet function |
| KR100305306B1 (ko) * | 1993-02-17 | 2001-11-22 | 존 펑크하우저 | 건식화학캐스케이드면역분석법및친화도분석법 |
| US5686597A (en) * | 1995-06-06 | 1997-11-11 | Incyte Pharmaceuticals, Inc. | Thrombin receptor homolog |
| US5922551A (en) * | 1997-03-20 | 1999-07-13 | Accumetrics, Inc. | Agglutrimetric platelet binding assays in blood |
| US6046051A (en) * | 1997-06-27 | 2000-04-04 | Hemosense, Inc. | Method and device for measuring blood coagulation or lysis by viscosity changes |
| US5932445A (en) * | 1997-11-07 | 1999-08-03 | Incyte Pharmaceuticals, Inc. | Signal peptide-containing proteins |
-
2001
- 2001-05-09 BR BRPI0110735-6A patent/BR0110735A/pt unknown
- 2001-05-09 JP JP2001583144A patent/JP2003532891A/ja active Pending
- 2001-05-09 MX MXPA02011017A patent/MXPA02011017A/es unknown
- 2001-05-09 CA CA002408850A patent/CA2408850A1/en not_active Abandoned
- 2001-05-09 KR KR1020027014988A patent/KR20030014219A/ko not_active Application Discontinuation
- 2001-05-09 WO PCT/US2001/011760 patent/WO2001086248A2/en not_active Application Discontinuation
- 2001-05-09 EP EP01934872A patent/EP1280931A4/en not_active Withdrawn
- 2001-05-09 AU AU2001261020A patent/AU2001261020A1/en not_active Abandoned
-
2002
- 2002-11-05 NO NO20025300A patent/NO20025300L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2408850A1 (en) | 2001-11-15 |
| EP1280931A4 (en) | 2005-02-09 |
| NO20025300L (no) | 2003-01-07 |
| JP2003532891A (ja) | 2003-11-05 |
| EP1280931A2 (en) | 2003-02-05 |
| WO2001086248A2 (en) | 2001-11-15 |
| WO2001086248A3 (en) | 2002-02-28 |
| NO20025300D0 (no) | 2002-11-05 |
| BR0110735A (pt) | 2007-05-08 |
| AU2001261020A1 (en) | 2001-11-20 |
| KR20030014219A (ko) | 2003-02-15 |
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