MXPA00012577A - Foaming composition for hair care - Google Patents

Abstract

The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterised in that it contains in an aqueous medium:at least an active principle selected among corticoids and retinoids;at least an anionic surfactant;at least an amphoteric surfactant;and a pro-penetrating agent.

Description

COMPOSITION FOAM FOR HAIR CARE DESCRIPTION OF THE INVENTION The present invention relates; foaming compositions for washing and treating the hair and / or scalp, which contains an amphoteric surfactant and a ptopepeptide / isi agent, as with the lysate process, said compositions. all the chronic diseases of the common. This disease is observed in 1.4 to 2.9% of the population. The scalp is one of the most common sites due to psoriasis, which causes a malaise, cysts, peeling, keratosis, pruritus and may also be responsible for a reduction in capillary density. The treatments used until now resort to salicylic acid, local steroids, anthralin or coal tar or wood tar. These treatments are unpleasant, especially when applying tar and require long applications, particularly when using hair ointments. Ref: 124763 In order to improve the quality of life of the patient, without reducing the therapeutic effect of the treatment, foaming compositions containing corticosteroids have been perfected. More specifically, the time of application of these foaming compositions is reduced with respect to the Patent BE 84515 discloses a composition containing the hydrochlorone in a solvent mixture consisting of 15 to 601 aliphatic alcohol, 15 to 601 propylene glycol and 5 to 60%, of a third solubilizing agent selected from the group consisting of hydroxy-2-ethyl salicylate, dipropiicetone and dimethyl cocobenzylamine chloride. EP 0 325 949 discloses a solution comprising at least 2.5 'of corticosteroids, of ? - ct O? or uc ex / U or uc f i 'n ri f-f £ > v-, f-? arit i m i crobi ano. However, the solvents present in these compositions tend to evaporate very rapidly. In addition, the fluidity of these compositions makes application difficult and it is usually necessary to apply these compositions by friction to allow efficient penetration of! or.? nrinrin ^ ns active, which causes greater irritation of the epidermis, or to apply these compositions and let them act for several hours, with the consequent discomfort of the patient. of the solvent, a foam containing a corosteroid, a foam-cutting agent, a propellant and a buffer was proposed in patent WO 962-376. The foam-cutting agent is composed of an aliphatic alcohol, water, a fatty alcohol and A non-ionic surfactant, however, when these foams are applied to non-ionic fibers, their resultant aesthetic appearance is not satisfactory and the scalp located under the keratin fibers can be treated insufficiently. i- - ± - J- Liild. i- u iUlI UC 1 ^ a- -? -? ¿? -? - £ -'-- Ctv ^ i j- ._ > li -i- Cl - - - 1. ^ C. »I / al / prs nt do auzus propi d es cos t ics The Applicant has now perfected a foaming composition having the enclosed properties, the compositions of the present invention, while they allow a good penetration of the active principles, they also present an improvement of the cosmetic performances of e the compositions for the treatment of skin or hair conditions, leaving the hair soft, elastic and non-greasy. In addition, these compositions are easy to rinse. The Applicant has also found that the foaming compositions of the present invention made it possible to obtain, surprisingly, a foam having improved volume and compactness characteristics compared to foam compositions for the treatment of skin conditions. : uero rte a n r o v i f- v- T -L dzi mxLL - > v -i or S-. r.L-.iL O c QC ni aq pC / / -3 O m iti -pup, i- C-l sorpr ndent, the corpositions object of the present invention are stable in time, allowing to avoid the precipitation of the principles assets and staying Therefore, one of the objects of the invention is constituted by a foam composition for the washing and treatment of the hair and / or of the leather fit 11. Another object of the invention is a method of washing and treating the hair and / or the scalp that applies this composition. An object of the invention is also a composition according to the invention for its use as a medicament.

An object of the invention is also the use of the compositions of the invention as a medicament and for the manufacture of a medicament intended to treat skin or skin conditions. hair Other objects of the invention will appear with a reading of the description and the following examples. The foaming composition for washing and treating the caoello and / or the scalp is essentially characterized in that it contains, in a medium, at least: - at least one active ingredient selected from corticosteroids and retinoids, - at least one anionic surfactant, i | . ' - r \ -y? _ - "i ~ r ~ -? * R? O r-, - ^ > ciiirprciq r- 1- ittt • -ni ru-, - - tL--? C -L / ~ v In the context of the present invention, corticosteroids can be chosen from alclometasone dipropionate, ameinonide, belamethasone dipropionate, betamethasone TJ benzoate, dipropionate a or betametaeone. , betamethasone valerate, budesonide, ciobetaeol propionate, preferably clobetasol propionate, clobetasol bromide, desonide, deoxyethasone, dexamethasone, diflorasone diacetate, and flurandrenoione, fiuprednidene acetate, fluocortolone, fiuccortin butyl, f1ooc inonide, fluocmolone acetonide, fluclcrolone acetonide, flumetasone pivalate, feudiiine hydrochloride, fluol, etholone, uridine / idioid -? u? j xoun c _L d C QLU of hydrocortisone, hydrocortisone butyrate, hydrocortisone valerate, acetat or metiiprednisolone, ometasone furoate, methylpreanisolone, prednisoione, tiidi acetonide "Cinolone or between pharmaceutically acceptable mixtures of the latter. The retirhoids can be chosen from the t-trans-tonic acid also known as tretinoin or amine acid A, adapalene, isotret moine, retmcl, ie vitamin A and its derivatives, such as acetate, palmitate or propitiate of retino !, the motretmide, the etretinate, the acitretma, the t-trans retm? dtu e zinc, retmoides of third generation optenidos by the addition of cyclic groups in the polyene side chain, also called arotinoides, or synthetic retinoids or between pharmaceutically acceptable mixtures of the latter.

Among the retinoids, adapalene, 4- [7- (1-adamantii) -6-methoxyethoxy-ethyoxy-2-naphthyl-3-benzoic acid, 2-hydroxy-4- [3-oxo-3- ( 3-tert-butyl-4-methoxyphenii) -1-propynyl] benzoic acid and 4- (3, 5, 5, 8, 8, -pentamethyl-5,6,7,8-tetrahydro-2-naphthylthio) benzoic acid . The particularly preferred active ingredient among corticosteroids is ciobetasoi-17-propionate. The active principle can be used in proportions of 0.001 to 51, preferably between 0.01 to 0.3% and more preferably between 0.05 and 0.1% by weight In the framework of the present invention, the nature of the anionic surfactants does not have the truly critical character. Thus, as an example of anionic or ilishable surfactants, alone or in combination, salts may be mentioned [in particular alkali salts, specifically sodium, ammonium salts, amine salts, salts of ami or alcohols or magnesium salts) of the following p -t- ^ c- '] O ^ p 1 A-ii i 1 in 1 f , q rr > or]! ~! c *,] m ""! P t "p v-? I: 1 f q A α alkylates idoetersulfates, alkylaryl polyether sulfates, monoglyceride sulphates, alkylsulfonates, 3i: 1 t? Fatos, aiquilamidosulfonates, the alkylsulfonates, a-silyphine-suifonates, paraffin-suifonates, alkylsulfosuccinates, aicylethylsulfosuccinates, alkylamidosuiphosuccinates, aminosulfosuccinamates, alkylisuiphathates, alkyl ether phosphates, acylsarcosylates, acyl isethionates and N-acylaurates, containing the alkyl or acyl radical of ef - ^ if? pnr a r, mr? i? o crf- >;? and ^ v ~ cs ^ c > ~ e2¡- -t ~ 2? -rn ec y ~ > l- e ^ H ^ ^ 1 0; * or? W c rl £ / - "a > ~ ^? - > io rt? a H i C * ~ *" i P ^ 1 a r í] preferably a phenyl or benzyl group. Among the also useful ammonium surfactants, the salts of ricinoleic, oalmitic, stearic, the copra oil or hydrogenated copra oil acids, the acyl-iactylates whose acyl radical comprises 8 to 20 carbon atoms.

A 3 rh? T om -i Ar ^ ^ i i * - > , -Ñ '-i r- > nr i l i 73 VCD f pri? i? I added a few anionics, such as alkylcarboxylic acids, as well as polyoxyalkylenated polyoxycarboxylic acid carboxylic acids, carboxylic polyoxyalkylenated carboxylic acids, carboxylic acidic carboxylic acids (CG_C2) and its salts, in particular those having from 2 to 50 ethylene oxide groups, and mixtures thereof.

Among the ammonium surfactants, ^ v -r? pe pr? ~? a l pn ^ c * p tt? p 7 p 1 a More particularly, ST prefers to use the I sp - T l c.t-civ-? N l -r -a t- river O ^ "i ^ f a? OT" i P? ori f, 1 pl marketed under the name "Texapon N70" '", the sodium lauryl ether suface, especially marketed under the name" Sipon AOS 225 UP * ", and the sodium riisuitate, especially the surfactant. Anionic agents can be used in proportions comprised between 0.05 and 501, preferably between I and 301 and more preferably of Active Material iM.A.) by weight with respect to 1 ac. DO; : to L; / "•» surfactants at n f o t o r, s "I 1 T"? I 7? Character has: r? T? Cc e or "arc of the present invention, can be in CSOCí i I r ~ i c v-T a n r ^ ^ e -i Tr »T n, a < c * ¿-z 1u 1naarias or tertiary 0 straight or branched chain with 8 to 22 carbon atoms and with at least one water-solubilizing anionic group (for example carboxylate, sulfonate, sulfate, phosphate or phosphonate); there may also be mentioned the alkyl (CB-Ci?) betaines, the sulfobetams, the alkyl (CS-C-c) to idoalkyl (d-Ce) betaines and the alkyl (CD-C) amidoaikyl Ci-Cß) sulfobetaines. Among the derivatives of amines, there may be mentioned the products marketed under the names MIRANOL, such as those described in patents US-2 528 378 and US-2 781 354 and of structures: R2-CONHCH2-CH -N (R3) (RJ (CH COO ~) wherein: R_ designates an alkyl radical derived from an acid R_-COOH present in the hydrogenated copra oil, a heptyl, nonyl or undecyl radical, R "designates a betahydroxyethyl group and R4 a group where 1: B represents -CH2CH_0X ', C represents - (CH?) z-Y', with z = 1 or 2, X denotes the group -CK_CH_-COOH or an atom of il ^ v-Á nn Y 'designates -COOH or the alkyl radical -CH_-CH0H-S0jH RG designates an alkyl radical of a fatty acid Ro-COOH in the copra oil or in the hydrolyzed linseed oil, an alkyl radical, especially in CT, Cy, Cl t or Cl! (an alkyl radical in C- and its iso form, an unsaturated C ^ radical.

These compounds are classified in e. ' dictionary; A, / ma 1 QQ tí,) ai (the designations Disodio Cocoanfodiacetato, Disodio T) i hate pn i 1 T) 1iS! do not In the case of other surfactants, cocolbetaines are particularly preferred, and, in particular, cocaine, especially commercialized cocaine. These amphoteric reactants can be UT i i 1 7 a *.? to nv? The values are between 0.01 and 301, preferably between 0.5 and 20%, preferably between I and 151 of A. by weight with respect to the total weight of the product. month in M.A. of the t eps 1 o a c1 o = ap3 eos and of the amphoteric surfactants ^ C t-r-O v? N? TTirin t-? i "-1- v ~ 0 and most preferably; .c 2 and 1. E C ire" 11- - ^ ~ "" i *? "Í c ** ^ ^ f T" Ti t ~ mi > r ~! »~ Rn? T ~ p f 3 fí 1 i f" l e p e r t c e n of the active ingredients, is Pvo f? or -not -substanting of the active compound present in the compound. Particularly, it is chosen from the volatile alcohols in C? -C4 / such as ethanol, isopropanol, between the polyhydric alcohols such as propiiengiol and between the glycol ethers as the ethoxydigiic'oi. The preferred propenetrating agent in the context of the present invention is ethanol. Propenetrating agents can be used in concentrations between 0.1 and % and preferably comprised between 5 and 10% by weight with respect to the total weight of the composition. The ratio between the proportion in M.A. of the anionic surfactants and the proportion of the agents p open tr nt s is preferably comprised between 0.1 and 10 and more preferably between 0.5 and 5 and even more , as r > > I decided to make an invention by improving its improved properties by adding, for example, cationic polymers, acrylic polymers, cellulose derivatives whether or not they are processed. The cationic polymers which can be used according to the present invention can be selected from among themselves and from > s in themselves to improve detergent compositions, namely those described in patent application EP-A-0 337 354 and French patent applications FR-A-2 270 846, 2 383 660, 2 598 611, 2 470 596 and 2 519 863. Still more generally, in the sense of the present invention, the term "cationic polymer" refers to any polymer containing groups R H? Pi rn? Pn QrUDn? rsH? n i. { -ns. Preferred cationic polymers are chosen from those containing motifs with primary, secondary, tertiary and / or quaternary amine groups which may either be part of the polymeric chain or be contained in a ral directly linked thereto. The cationic polymers used generally have a molecular weight in the number comprised xi c: ^ and > . x to u? iaQ aiLt ii LC and μx cx l cilLci cli The range between 00 ~ and 3.10 aproximadamente approximately. Among the cationic polymers, quaternized proteins (or protein hydrolysates) and polyamines of the polyamine, polyaminoamide and quaternary phenylammonium type can be mentioned more particularly. These are known products. Proteins or hydrolysates of quaternized proteins are in particular modified polypeptides which contain at the end of the chain or are transplanted thereon, quaternary ammonium groups. Their molecular mass can vary, for example, from 1,500 to 10,000 and in particular from 2,000 to 5,000 approximately. Among these compounds, mention may be made in particular of: - collagen hydrolysates with triethylammonium groups such as the products sold under the name "Quat-Pro E" by the company MAYBROOK and designated in the CTFA dictionary "Triethonium Hydrolyzed Collagen Ethosulfate"; - Collagen hydrolysates with trielammonium chloride and trimethylstearylammonium chloride groups, sold under the name "UAT-Pro S" by the Maybrook Company and designated in the CTFA dictionary. "Steartrimonium Hydrolyzed Coil agen"; - hydrolysates of animal proteins that have r i met i 1 benzylammonium groups or such as the products sold under the maize "Crotem BTA" by the CROD / v Company and designated in the CTFA dictionary - the protein hydrolysates having in the polypeptide chain quaternary ammonium groups with at least one alkyl radical having 1 to 18 carbon atoms. Among these protein hydrolysates, they may include, among others: ^ roquat L "whose quaternary ammonium groups .Iqurlo in Cu - the" fi? Frnn? R / - > ri "t -n -i T te" -r -? ~ p ^ - "" and x- ^. ^^^ ".U" .. xv,, "- the" Croquat S "whose quaternary ammonium groups comprise at least one alkyl group having 1 to 18 carbon atoms. These different products are sold by the : as? as or h: iroiizaaos cuate: .zaaos so: ej e p. What do you think of the rormuia? in which .x.β is an anion, na, an aci.a, or org, ni.co or mineral, A designates a protein residue derived from collagen protein hydrolysates, R5 designates a lipophilic group with up to 30 carbon atoms, RD represents an alkylene group with 1 to 6 carbon atoms : arbono Mention may be made, for example, of the products sold by the Inolex Company under the name "Lexein QX 3000", designated in the CTFA dictionary "Cocotr imonium Collagent Hydrolysate".

The prroo can also be cited !! rt a •? quaternized ales such as wheat, corn or soy proteins: as quaternized wheat proteins, those commercialized by the Croda Company can be mentioned: and QQ? 1M "in the CTFA dictionary" Cocodimonium Hydrolysed heat protein ", "Hydrotriticum QL" designated in the CTFA dictionary "Laurdimonium hydrolysed wheat protein" or also "Hydrotriticum QS", designated in the CTFA dictionary "Steardimonium hydrolysed wheat protein." The polymers of the polyamine, polyamidoamide, polyamonic quaternary type, usable in accordance with the present invention, which can be mentioned in particular, are those described in the narpnrp? -Fv-rir-OQ cr n ° AM A "í / 1 fi A 9 * - \? QQ T "i" T P * metacriiate diaqualamoaquilil quaternized or not, such as the products sold under the denomination? ^ uiw C v_i S, as for example Gafquat 734, 755 or HS100 or the product called "Copolymer 937". These polymers are described in detail in French patents 2 077 143 and 2 393 573. (2) The cellulose ether derivatives that quaternary ammonium described in the French patent 1 492 597 and in particular the polymers marketed under the names "JR" (JR 400, JR 125, JR 30M) or "LR" (LR 400, LR 30M) by the Union Carbide Corporation. These polymers are also defined in the CTFA dictionary as ammonium with an epoxide substituted by a trimethylammonium group. (3) Cationic cellulose derivatives such as cellulose copolymers or cellulose derivatives transplanted with a quaternary ammonium hydrosolubic monomer and described in particular in US Pat. No. 4,131,576, such as hydroxyalkyl celluloses, such as hydroxymethyl-, Hydroxyethyl- or hydroxypropyl cellulose transplanted ir id idial i l mo ni o. Products coded to the markets that respond to this goal. more particularly what products L 200"and" Celq- -nt H 100"for the National Society Qt a v ~ t ~ - V > (4) The cationic elisaccharides described more particularly in US Pat. Nos. 3 589 57I and 4 031 30 ~ i? = = > i like guar gums containing trialkyl onium cationic. For example, guar gums modified by a salt (for example chloride) of 2,3-e? Oxypropyl trimethylammonium are used. Such products are marketed, in particular, under the trade names of JxAGUAR C13 S, JAGUAR C 15, JAGUAR C 17 or JAGUAR C162 by society i-i ii, Y H j_? • (5) polymers formed by piperazil and by divalent radicals to qui leno or hixydiaxyalkylene with straight or branched chains, optionally interrupted by oxygen compounds, particular are given to the patches (6) water-soluble polyamphenamides prepared in particular by polycondensation of an ac compound or a polyamine; these poly minoamides thousand uci x v auu J ii d UJ.a? Aila UA Iiaiuii uíliia / il -LO aceti inio, a bis-haio cildiamina, a bis-halogenurc of alkyl or also by an oiigomer resulting from the reaction of a bi-functional compound reactive towards a bishalohydrin, of a bis-acetidinium , of a bis-haioacylidiamine, of o - a | A * / a? ? ae ae one or i T q l r? i a rl s n ^ "í P ^? v 'H ¡O H p 1 1 Ti H? ~ í t¡r; fl H Ì. - unsaturated, using the crosslinking agent in proportions ranging from 0.025 to 0.35 mol per amine group alkylated or, if they contain one or more tertiary, quaternized amines. Such polymers are described in particular in the patents French 2,252,840 and 2,366,508; (7) the polyaminoamide derivatives resulting from the condensation of polyalkoylenes polyamines with polycarboxylic acids followed by an alkylation by bifunctional agents, for example, the adipic acid-diacmydiahydroxyalkyldiallylenetriamine polymers in which the alkyl radical comprises from 1 to 4 carbon atoms.

• A A -i 1 > 1-? 1 propilc. These polymers are described specifically in French patent 1,583,363. Among these derivatives, mention may be made more particularly of the polymers adipic acid / dimethylamine hydroxypropyl / diethylene triamine sold under the name "Cartaretine F, F4 or F8" -? by the Sandez society. (8) polymers obtained by reacting a polyalkylene polyamine with two primary amine groups and at least one secondary amine group with a dicarboxylic acid chosen from diglicic acid and saturated aliphatic dicarboxylic acids containing from 3 to 8 carbon atoms. The molar ratio between the polyalkylene polyol and the dicarboxylic acid is W? 1mHr /. LnUUí UAU or Cn XX l I L-Q t. n, p • • _iX _y i X-, Ti •. l X, "X], U - = * rn -lJ L ^ Almlii, ai ti a L i ui r x] Cl P i l O h i í Tl ? -i nm p TQ 1 i A m an m 1 cj v- JP 1 secondary amine group of the polyaminoamide between 0.5: • n i an: spe < . ricamei e Patents These types are commercialized in the I Ai-iCi Ti? A 'Hercosett for the name of the company Hercules in the case of eopo x ime r o ae acide' or dimethyl diallyl ammonia such as homopoiimers containing a major component of the chain motifs corresponding to formulas (VI) or (VI): designate an alkyl group with 1 to 22 carbon atoms, a hydroxyalkyl group in which the alkyl group preferably contains 1 to 5 carbon atoms, a lower amidoalkyl group or R10 and R1X may designate together with the nitrogen atom to which they correspond, heterocyclic groups such as piperidinyl or morpholinyl; . ' Yü is an anion such as bromide, chloride, acetate, borate, citrate, ta-rtrate, bisulfate, bisulfite, sulfate, phosphate. These polymers are specifically described in the French patent 2,080,759 and its certificate of addition 2,190,406. Among the polymers defined above, mention may be made more particularly of the homopolymer of dimethyldiallylammonium chloride sold under the name "Merquat 100" by the company Merck. (10) the quaternary diammonium polymer with recurring motifs that correspond to the formula: formula (VII) in which: Ri3 'Ri4' Ri5 and Ri6 'identical or different, represent aliphatic, alicyclic or arylaliphatic radicals with 1 to 20 carbon atoms or hydroxyalkylaiphatic radicals formulas in which k and t are equal to u or i, sienao the sum k + t equal to 1; R 12 denotes a hydrogen atom or a methyl radical; Rio Y Rn '- independently of each other, designate an alkyl group with 1 to 22 carbon atoms, a hydroxyalkyl group in which the alkyl group preferably contains 1 to 5 carbon atoms, a lower amidoalkyl group or Rio and R_ can designate with the nitrogen atom to which they correspond, heterocyclic groups. . . , -r? such as ^ i ^ and idiniio or mo foiinilo i is an anion such as bromide, chloride, acetate, borate, citrate, tartrate, bisulfate, bisulfite, sulfate, phosphate. These polymers are specifically described in the French patent 2,080,759 and in their certificate of d Q X C 1 1i ¿. X V. * - * O. Among others, the dimethyl urea diammonium homopolymer sold under the name "Mersuat 100" DOG by Merck, has been among the most important. - > - > ) pl .i erc ae di.amo io 'v at er. to. n Recurring reasons that respond to the n T-rm i I p XUXllLUXI ÍUT T \ V x j. which: Rl3, Ru, RtJ and Rio, identical or different, represent aliphatic, alicyclic or arylaliphatic radicals with 1 to 20 carbon atom or radicals h. y y i a 1 11 -í 1 a l i i t i i n f i p Nitrogen atoms to which the occu tionally correspond a second time? "i -rp v-pt-vf- p rl well K ^, K. ,, Rl3 and Rif,: a? alkyl in Ci-Co linear ox TA Xt- xt L -.- HAl / A o_)" I 1 c - a nitrile, ester, acyl, amide or - 7 0-P-D or -CQ-NH-R --- p group where P.-7 is a ü :: aieG or branched, saturated m = aturated, / oue may contain, bound or azurri groups sulfoxi or, sulfo a, U -: 11 i 1- n r n amide or ester and X, - < = > designates an anion derived from an atom nitrogen atoms to which a piperazinic cycle corresponds, in addition if Ax designates a 1 i: aaole, unsaturated saturated or unsaturated radical, it may designate a group (CH2) - C0-D-OC- ( CH2) in which D designates: a) a giicol residue of the formula: -0-ZO-, wherein Z denotes a linear or branched hydrocarbon radical or a group which corresponds to one of the following formulas: -ni -GK -Í -? t? • 0] -CH2-CH (CH-) - where x and y designate an integer from 1 to 4, which represents a defined and unique polymerization degree c any number from 1 to 4 representing a degree of b) a bis-secondary diamine residue such as a piperazine derivative; c) an amino-bis-primary radical residue: -NH-Y-NH-, where Y denotes a linear or branched hydrocarbon radical or the bivalent radical -CH.-CH ..- -F > ? rm l. It is preferable that X is a tai anion such as the cyano or bromide, these polymers have a molecular mass in number generally between 1,000 and 10,000.00 Polymers of this type are specifically described in US Pat. French patents 2,320,330, 2,270,646, 2,316,271, 2,336,434 and 2,413,907 and US Patents 2,273,780, 2,375,853, 2,388,614, 2,454,547, 3,206,462, 2,261,002, 2,271,378, 3,874,870, 4,001,432, 3,929,990, 3,966,904, 4,005,193, 4 p ~ IÍI ~ 7 u ~ f, ~ ~ p ~ -r.-3 non (1-. Polymers of quaternary polygons Constituted by reasons of formula (VIII): TO- in which: Rí, Ki5 R2? and R2i identical or different, represent a hydrogen atom or a methyl radical, pr i i n n? Tii 1 n R -? i oh i 1 n R-HÍTr XÍD ODÍ l? O - CH2CH2 (OCH2CH2) ¡.OH, where p is equal to 0 or to an integer between 1 and 6, with the proviso that R1, Ri i, R.AA and RA, do not simultaneously represent an without ? r * cs c tß es, are whole numbers q is equal to 0 or to an integer comprised between tre 1 and 3, V i. r s_- > c \ _s f? > a nrn »T i n 1 n < * (£.? / A designates a radical of a dihalide or preferably represents -CH2CH_-0-CH-CH2-) is found in the patent application EP-A-122 324. For example, there may be mentioned among these ios. products "Mirapol A 15", "irapol AD1", "Mirapol AZI" and "Mirapol 175" sold by the company Miranol. (12) homopolymers or copolymers derived from acrylic acid mclicacrylic and containing molds: R, 'il 9 »CH2-C CH2 c CH2" C 1! O = c O =! = C O = C I or i NH O I V r 1- R 2 $ ^ 4 M. R »'N + - Ri4 1 R2S ** 7 R 23 y / o in which the groups R_: independently designate H or CH, groups A, independently designate a linear or branched aleoyl group of 1 to 6 carbon atoms or a hydroxyalkoyl group of 1 to 4 carbon atoms, the groups R_, R_ , R_5, identical or different, independently designate an alkoyl group of 1 to 18 carbon atoms or a benzyl radical, the groups R and R_- represent an atom a n í p? to ? X aesi na Ü? ?,, ejer ejer ejer por por por por por por por por por Ap Ap Ap Ap Ap Ap Ap Ap Ap Ap Ap Ap Ap Ap. The comonomer (s) that can be used in the T-p qi-nr-? OTA He le copolymer s corresponding to oAün n IB. f ili de i ^ s a ^ ^ i 1a i ^ ^. ™ p r ""? Lamiria5; ri - > acrylamides and methacrylamides substituted for nitrogen by alcoves 11 interiors, alcohol esters, acrylic methacrylic acids, vinylpyrrolidone or vinyl esters (JJ) Quaternary polymers ae e ~? ei .o os:? a. .as t c Q ñ 37. gives B. A with the no ore ae «Uru VPFUVI L? pf't VfC T TA O POLYAMINE "in the CT C on i t i ng FA 1 crosslinked .oruro t? e t? e? lio!" P! Vi "! e P" • "" > ! T ^ - ^ 1 i mp i I m, n i / such n the dii and iiaminoet il t t can quaternized by the chloride pía n i 1 A A? O 13 rii iTli a ln of methyl, the homo or copolymerization being followed by crosslinking by an unsaturation compound i, in particular methylene bis acrylamide. more particularly a copolymer can be used ammonium (20/80 by weight) in the form of dispersion with 50 u. by weight of said copolymer in mineral oil. This dispersion is marketed under the name of "SALGARE SC 92" by the company ALLIED COLLOIDS. A crosslinked homopolymer of methacryloyloxyethyl trimethylammonium cioride with about 50% by weight of the homopolymer in mineral oil can also be used.This disoersion is marketed under the "SALGARE SC 95" by the company ALLIED . { ) 1- vy rrss .onicos usable in my invention are poiyalkyleneimine; in? in? m. viniipipamio, conaensaaos de quaternary and .os derivatives of chitin. r cntc the polymers chosen from the one to which R, represent the methyl radical, Ai * _ / Bj. represents radical radical of tor- _a - C11_ > - and X "represents the anion l? ~ n - rip? Tri / - nnc rp ri n mA it M vám p '~ lpl cottiputate de fo r p 1a (VII.) n which R i-- R1 represent the ethyl radical, RAJ and R b represent the represent the radical of formula -. { CH_) 3- and X recre = enta the bromide anion (denominated DOS t er lormente líexc'iußrc * PAK I Among all the cationic polymers that can be used, it is preferred to apply the compounds described above in points (3) and (4) According to the invention, the cationic polymers can represent 0.001% to 10% by weight, preferably from 0.005% to 5% by weight, and even more preferably from 0.01% to 3% by weight, of the weight total of a? m? l A l A nf 1 A 2 1 TT 1 A cosmetically acceptable solvents, different from the propenetrating agent such as onoalcohols, mixture . Among these solvents, polyethylene glycol, glycerol and sorbitoi may be mentioned more particularly. The solvents are preferably used in proportions of 0.5 to 10% by weight with respect to the total weight of the composition. The pH of the compositions is preferably between 2 and 9 and in particular between 3 and 8. For clobctasol propionate, the pH is conveniently between 5.5 and 6.5. It is adjusted by cosmetically acceptable acidifying agents or acidifying agents.

The compositions according to the invention can also contain other adjuvants used in foaming compositions such as shampoos and especially ceramides, such as those described in French patent FR 2 673 179, glycoceramides, well-known nonionic surfactants which can * o- c AA rro r- C Q i O- xx T- x t- ~ v? - x 1_ d 3,. 1 Other fatty acids polyethoxy, polypropoxylated or polyglycerolated fatty chain with for example 8 to 18 carbon atoms, with the number rt and i i p r ri p n and i r n p r p? i I p p espe; le lens z number ae ¡c _. to. JU The copolymers of ethylene oxide and of propylene, the condensates of ethylene oxide and of propylene over fatty alcohols can also be mentioned; the polyethoxylated fatty amides with preferably 2 to 30 moles of ethylene oxide, the polyglycerolated fatty amides with an i -r-i-i-1 glycerol and in particular 1.5-yyroxy; the polyethoxylated fatty amines with pre te rcnt emeni to 3 moles of ethylene oxide; the fatty acid esters of sorbitan oxieti reacted with 2 to 30 moles of ethylene oxide; The fatty acid esters, the fatty acid esters of the 1 cs r and rr 1"go * the aiky-glycolicides, the N-alkylaminic derivatives, the amine oxides such as the alkyl (Cic-Cu) amines or the N-acylaminopropyimorpholine oxides, the alkylpolyglycosides and the polyglycerolated fatty acid alcohols The compositions may also contain thickening agents selected in particular from sodium aiginate, gum arabic, cellulose derivatives such as ethyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hi AA i -n AA il - > (alp > c * a 1 a cr 1 i guar gum or its derivatives, xanthan gums, scleroglucans, crosslinked polyacrylic acids, polyurethanes, acid-based or maleic anhydride copolymers, thickeners associative carriers of natural chain fat chains as the product PEMÚLEN The thickener can also be obtained by mixing polyethylene glycol and stearates or polyethylene glycol distearates or by mixing phosphoric esters and amides. The compositions according to the invention may also contain dyes, viscosity modifiers, pearlizing agents, moisturizing agents, anti-dandruff agents, anti-seborrheic agents, sunscreens, proteins, vitamins, α-hydroxy acids, salts, perfumes, preservatives, sequestering agents, softeners. , foam modifiers, detcxificantes ossm zcias. Also, conditioning agents such as natural oils ix xlx can be used? u u u u u j, cyclic or fatics, linear or radi- fied (saturated or not, volatile or non-volatile organomodified silicones, soluble or nc, perfumed or fused oils, polybutenes and polyisobutenes, fatty esters that occur in liquid, pasty or solid form, esters of polyhydric alcohols, glycerides, natural waxes and synthetics, silicone gems and resins, quaternary ammonium salts such as the compound classified in the CTFA dictionaries, 7th. In the context of the present invention, the compositions are presented more particularly in the context of the present invention, the term "Quaternium-22" and the name "Ceraph '60", or mixture of these different agents. liquid form, eventual thickened.

They can be used in your state or diluted before use. The compositions according to the invention are more particularly used as shampoos for the treatment of hair or scalp.

In wet or dry hair, then a light massage is preceded by forming a foam, rinsing and eventually applying again the shampoo followed by a nine rinse with water. An object of the invention is also a foaming composition tai as defined above for its application as a medicament. The present invention also has for its object to the elaboration of a medicine designed to treat the affections of the scalp. compositions according to the invention? n p? p ca a r-ti '..1 u1 1 id vm p A tiA t "AO t O Ai' atation of eczema, of eczematous or psoriatic erderderies, of pruritic lesions, of chronic erythematosus lupus, of psoriasis and plaque parapsoriasis.

These treatments generally require an an l l A A I I I I "5 times a week, and then several illustrative and non-limiting information will be given below.

P \ vr T 'The following shampoo is prepared: - Texapon N7C (Sodium lauryl ether sulfate (2 mol OE) ai 70% M .A.) - Dehyton AB 30"v (? 32% M.a.

- T? Diiscutol '"' (etox idiy 1 icol) 1 u g - Propionate d ciobetasoi 0.05 g - Jauuar C162"'(hidi.? Ximetilquai - * i H 1 Ó r- * t" i r ~ r \ cs pH6 Water desminerai_ tadc c 100 g h T T TvT w T C \ Dehyt? N AB 30"'.ocoiib taina ai 32% M.A.) Jaguar C162" (h.' Dr? Ximeti lyuar t rimet i i amon i o; 0.5 g Siphon x.0S 225 P "(28% sodium laureth sulfate MA) Ethanol (95/96%) ng Clobetasoid propionate ñ r- ^ g Benzaiconium chloride 0/00 Lactic acid? - SP 6 Demineralised water s 1 0 pg i_, Ji_, M LO lil frepar, .ente - Texduon N70"(Laurether sulfate from a? di? X / y - Dehyton AB 30"" '(Cocui lbetaína to 32% M.A.) 6 g - Transcutol (ethoxydigl icol) 1 0 g - Adapalene 0.05 g - Jaguar C162 '(hydr? Ximetilguar trimetiiamonio; u, 5 g cs pH6 - Water P.Liiií-ira iza cs 100 g GEMPLO IV The following shampoo is prepared: Sipón AOS 225 UP (sodium lauryl ether sulphate at 2% MA) J g- Dehvton AB 30"(Cocoi Ibetaina ai 31% MA) 6 grr, q A 1 (QL Q (Á5- Í 10 g - Benzalkonium chloride 0.01 g - Jaguar C162". {Hydroxymethyl ura trimethylammonium; 0.5 g-" opionate of - Lactic acid - Demineralized water cs 100 g T IGlU TTXGI TllTlJTx-? G-, VT The following shampoo is prepared: - Celquat SC 240"(P? Licuaternio 10) 2 g- - Texap? N N70 ^ (Laurylétei bulfato de c AGI i A í / T ?? I p ñTT I al "fj5 'M ü, 1 7 fT - Dehytoii AB 30"(Cocoylbetaine at 32% M.A.) 6 and - Rewoquat B50"(Benzalkonium Chloride 50%) 0.01 g - Citric acid, 1H_0 0.24 g - r -? t- -r ~ - - r? r c ^ i -i 014 *? CI CI - clobetasol propionate 0.05 g: s 100 Vi The following shampoo is prepared: - Celquat SC 240 (Poiicuaterni? 10) 2 g- - Texap? N N70 (Lauriieter sodium sulfate (2 moles OE, 70% MA ) 17 g - Dehyton AB 30"(Cocoi Ibetaina at 32% MA) 6 g Re oquat B50" (Clururu of benzalkonium 50%) 0, 01 g Ethanol (95/96%) 10 g - Propionate of 0.05 g - Water des ineralizada csp 100 g EXAMPLE VII The following shampoo is prepared: - sodium citrate, 2H_0 2.6 g 'arahidroxybenzoate 0.1 g- - Celqudt SC 240"(Pultrude nio 10) g- - Texapon N70 (Sodium lauryl ether sulfatu (2 moles OE) at 70% M.xA.) 17 g - Dehyt? P AB 30"(C? C? Ilibin 32% M.A..)) O g - Propionate of L /, J ^ g - Water p? U? V-? t? . "a p csp 100 g LULlhl JJU l X x. X The following shampoo is prepared: - Citric acid, 0.24 g - Sodium citrate 2.6 g - Ceiquat SC 240 (P? Licuaterni? 10) 2 g- - Texapon N70"(Sodium laurylétei sulphate (2 moles OE) at 70% M.A.) 17 g - Dehyton AB 30" "(32% cocoylbetaine M.A.) 6 g - clobetasol propionate 0.05 g - ¿Tapoi 'i / yóíí i * g - Purified water csp 100 g EXAMPLE IX The following shampoo is prepared: - Jaguar 0162 ^ (hydrimethyl trimethyl ammonium) 0.5 g - Qui exano HC (32% cocoylbetaine M.A.) 6.0 g - Sipón AOS 225 UP "(sodium lauryl ether sulfate ux 1 x ~ - p 5? - T xvxf.A • / I 43, 0 g x_> g? X_ \ gt; ~> / _? / 10, 0 g - "xDt_ n_jJJAxi ./- A -? Dr? R cs r L * x? C i-uüux 0, 05 g - e ocjuat B50 (Benzalkonium Chloride 50%) 0.01 g 100 g The following shampoo is prepared: - Jaguar CI62"(hydr? Xime ilguar trimetiiamonio) 0.5 - Texapun N70"(Sodium lauryl ether sulphate (2 moles OE) at 70% M.xzv.) 17 g - Dehyt? N AB 30"(C? C? Ilbetaine at 32% M.A.) 6 g - Rew? UuaL R50" (Benzalkonium chloride 50%) 0.01 g 3y Ethanol (95/96%) g Adapalene g Demineralized water 100 g tr TT7M-DT r \ Y T The following shampoo is prepared - Jaguar Cl 62"(hydroxim tilguar 0, - Texapon N70"(Sodium lauryl ether sulfate (2 moles OE) at 70% M.? A ?.) g - Dehyton AB 30"(C? Coylbetaine ai 32% M.A.) or g - Rew? Quat B50"(Benzalkonium Chloride 50%) 0.01 g - V i r "a a! O / Q £. ° - i 10 g - To L ^ _? _ U? / (j. ad rp.ant? -6-methox? ethoxy? methox? - '-naphthyl] benzoic 0.05 g csp 100 g t? TT7MDT Cl Y T T The following shampoo is prepared: - Jaguar C162"(hydr? Xiipe t íiguar trimotilamonio) 0, 5 - Texapori N70 (Sodium lauryl ether sulfate (2 moles OE) ai 70% M.A.) 17 g - Dehyt? N AB 30 * (C? Coiibetaína to 32% M.A.) 6 g - Rewoquat B50 (Chloride and beiizalc? Ni? 50%) 0.01 g - Ethanol (95/96%) - 2-Hydroxy-4- [3-OXO-3- i -methoxy-pl] -l-propynyl acid ] ben. - Demineralized water csp 100 g EXAMPLE XIII The following shampoo is prepared: - Jaquar C162"(hydroxy etiiguar trimethylammonium) 0.5 g -. 10 - Texapon N70"(Sodium lauryl ether sulphate { 2 m or 1 is OE) ai 70% A.) 17 g - Dehyt? N AB 30"í C? Coiibetaína to 32% M.A.) 6 g - Rew? Quat B50"(Benzalc? Ni? 50% Chloride) 0.01 g - Etapoi '95 / 96V1 10 g l -í - 7l A i A A A -. { ~ o The following shampoo is prepared: - Texapon N70 (Sodium iiiiétei sulfate and 2 moles OE) at 0% M.A.) 17 g - Dehyton AB 3C TTocoi Ibe taina at 32% M.A.) 6 g - Methocel E4M (? Rox? Propyl metli cellulose) 1 g 1H_0 0.24 g - 2H20 sodium citrate, or g - Cerafil 60 (Quaternium 22) 0.5 g - clobetasoi propionate 0.05 g TTr? ^ DA? XxA xI-? Q? / Q 10 g - Demineralized water cs 100 g The compositions of the aforementioned examples I to XIV are stable during storage and have a satisfactory foaming effect. A clinical study in which a composition according to example IX was used as a shampoo, once a day for two weeks applied to wet hair and left in contact for 10 minutes, to be rinsed, allowed to be observed in affected patients. psoriasis, a reduction in the level of the scalp of the erythema in 37%, of the ae: r ae. hyperkeratosis in 50% see the pruritus in a 3 'or It is noted that in relation to this date, the method known to the applicant to carry the invention is the conventional one for the manufacture of the objects or products to which it refers.

Claims (10)

1. Having described the invention as above,

   za < Foaming composition for washing and treating the hair and / or the scalp, characterized in that it contains in an aqueous medium: at least one active ingredient selected from corticosteroids and retinoids, - at least one anionic surfactant, less an amphoteric surfactant and a propenetrating agent.
2. 2. Composition according to claim 1, characterized in that the corticosteroids are chosen from among the diprcpionate of alclometasone, amcinonide, becylammethasone dipropionate, betamethasone benzoate, betamethasone dipropionate, betamethasone valerate, budesonide, propionate. of clobetasol, preferably clobetasoi propionate, clobetasol butyrate, desonide, deoxyethasone, dexamethasone, di-florasone diacetate, di-flucortolone valerate, fiurandrenolone, fiuprednidene acetate, fluocortolone, fluocortin butyl, fluocinonide, fluocinolone aceto ida, fluclorolone acetonide, flumethasone pivalate, feudilma hydrochloride, flumetolone, halcinonide, hydrocortisone, hydrocortisone acetate, hydrocortisone butyrate, hydrocortisone valerate, methylprednisolone acetate, mometasone furoate, methylprednisolone, prednisolone, acetonide a lamcinolone, or between mixtures pharmaceutically > acceptable from the latter.
3. 3. Composition according to claim 1 or 2, characterized in that the retmoids are chosen from the t-trans retinoic acid, adapalene, isotretinoin, retinol and its derivatives, such as acetate, palmitate or propienate. retine !, the motretmide, the etretinate, the acitretma, the t-trans zinc retinoate, the arotinoids, the synthetic retinoids or between pharmaceutically acceptable mixtures of the latter. or
4. 4. Composition according to claim 1 or 2, characterized in that the active principle is chosen among the clobetasol 17-prcpionate, adapalene, 4- [7- ladamantyl) -6-ethoxy-zefox-methox? -2-naphthyl] benzoic acid, 2-h? Drox? -5-4- [3-oxo-3- (3-tert-butyl-4-methoxyphenyl) -1-propynyl] benzoic acid and 4-hydroxy acid (3, 5, 5, 8, 8, -péncame i _ 5,6,7, 8-tetrahidrc -2 -naftiltio) benzoico. Composition according to any one of Claims 1 to 3, characterized in that the anionic surfactants are selected from the salts of the following compounds: alkyl sulfates, alkylene bisphosphates, alkyl sidoethersulfates, alkylaryl polyether sulfates, onions and the like. sulfates, the alkyphosphonates, the

   1U1Ai Al uri! S, aiquiiapisuitonatos, a-olefin-sulphonates, paraffin < sulfonates, acids, succinatides, alkyl sulphides, alkylsulfoacetates, aikido-phosphates, osmagents, aci. and the N-acyltaurates, and between the salts of the oieic, ricinoleic, palmitic, stearic acids, the copra oil acids or the hydrogenated copra oil, the acyl lactylates; and among the acids of iia niaceae uroniecs and their salts, as well as the polyoxyalkylenated carboxylic alkyl (C "-C_,) ether carboxylic acids, the polyoxyalkylenated alkyl aryl ether carboxylic acids, the alkyl C

   C \ pmi A? Polyoxyalkylenated carboxylic ether and its 6. Composition according to any of claims 1 to 5, characterized in that the anionic surfactants are chosen from the salts of aiquilsulfatbs and alkyl ether sulphates. Composition according to claim 6, characterized in that the anionic surfactants are chosen from sodium lauryl ether sulphate and sodium lauryl sulfate. 8. Composition in accordance with any

   10 of claims 1 to 7, characterized in that

   aliphatic secondary or tertiary amines, (C -C2 betamas, sulfobetaines, alkyl) amidoaikyl (C.-C betaines and alkyl (Cj-C_v)

   9. Composition according to any of claims 1 to 8, characterized in that the aforementioned thickeners are chosen from among the claims of claim 1, characterized in that the amphoteric surfactants are chosen from the cocamidopropyl betaines, the cocamidopropylhydroxy suitaine, the cocoylbetaines. 11. Composition according to any one of claims 1 to 10, characterized in that the propenetrating agent is chosen from the alcohols which are volatile in Ci-C4 and between the polyhydric alcohols. 12. Composition according to any of claims 1 to 11, characterized in that the propenetrating agent is chosen from ethanol, isopropane, propiienglycole and ethoxydiglycol. 13. Composition according to any of claims 1 to 12, characterized in that the r > v? ^ i r > ia * - f- i to 1 ~ "1 in ratio of 0.001 au, preferably between 0.01 to 0.3% and more preferably between 0.05 and 0.18 in weight with respect to the total weight of the composition 14. Composition in accordance with any of the characteristics characterized because the t e11 = iu ac 11vo used in proportions of o re < -ent between 30% and more em and:;.)% ac .A. By weight with respect to the 15. C '"1"' - osition according to any one of claims 14, characterized in that the n ¡nns? I 1 anza li za; in proportions of

   0.01 and 30%, preferably between 0.5 and 20% and more preferably -nrre 1 and 15% in M.A. of weight with respect to the total weight of the composition.

   16. Composition according to any of claims 1 to 15, characterized in that the propenetrating agent is used in concentrations of between 0.1 and 25% and preferably comprised between 5 and 10% by weight with respect to the total weight of the composition. 17. Composition according to any of claims 1 to 16, characterized in that the ratio between the proportions in M.A. of the anionic and amphoteric surfactants is comprised between 1 and 20 and preferably between 2 and 10. Composition according to any of claims 1 to 17, characterized in that the ratio between the proportion in M.A. of the anionic surfactants and the proportion of the propenetrating agents is between 0.1 and 10, preferably between, and. Composition according to any one of Claims 1 to 18, characterized in that the composition also contains cationic polymers chosen from quaternized proteins, polymers of the polyamine, polyaminoamide, quaternary polyammonium type, polyalkyleneimines, polyamine condensates and epichlorohydrin quaternary polyureylenes and chitin derivatives.

   ae reivinations i to 19, characterized in that the cationic polymers are chosen from the ether derivatives of quaternary celluloses, the cyclopolymers and the

   21. Composition according to claim 19 to 20, characterized in that the cationic polymer represents 0.001% to 10% by weight, preferably from 0.005% to 5% by weight, and even more preferably from 0.01% to 3% by weight with respect to the total weight of the final composition. 22. Composition according to any of claims ia 21, characterized in that the pH of the compositions is between 2 and 9, preferably between 3 and 8 and more preferably between 5 and 6, 5. 23. Composition in accordance with any from Claims 1 to 22, characterized in that the composition also contains nonionic surfactants and / or ceramides and / or glycoceramides. 24. Composition according to any of claims 1 to 23, characterized in that the composition contains thickening agents. 25. Composition according to any of claims 1 to 24, characterized in that the composition also contains dyes, viscosity modifying agents, nacreous agents, moisturizing agents, anti-dandruff agents, antiseborrhoeic agents, sunscreens, proteins, vitamins, a-hydroxy acids ,
5. 5 salts, perfumes, preservatives, sequestrants, softeners, foam modifiers, detoxifiers or their mixtures. 26. Composition according to any of claims 1 to 25, characterized in that ia

   The composition also contains conditioning agents such as hydrogenated or non-hydrogenated natural oils, linear or branched (saturated or non-saturated), silicones, whether volatile or not, organomodified or not, soluble or not, perfumed or fluorinated oils, polybutenes and polyethylene. sec es, fatty esters which are present in liquid, pasty or solid form, the esters of polyhydric alcohols, glycerides, natural or synthetic waxes, gums and resins of silicones, quaternary salts or the composition according to claim 26. , characterized in that the composition also contains quatern? -22 28. Composition according to any of claims 1 to 27, characterized in that it is in the form of liquids, possibly thickened 29. Composition according to any of the claims 1 to 28, for application as a medicament 30. Use of the composition as defined in any of the claims. 1 to 28, for the elaboration of a medicament intended to treat the affections of the scalp.