MX9801171A - Proceso para la produccion de acido 4-amino-1-hidroxibutiliden-1,1-bisfosfonico o sales del mismo. - Google Patents

Proceso para la produccion de acido 4-amino-1-hidroxibutiliden-1,1-bisfosfonico o sales del mismo.

Info

Publication number
MX9801171A
MX9801171A MX9801171A MX9801171A MX9801171A MX 9801171 A MX9801171 A MX 9801171A MX 9801171 A MX9801171 A MX 9801171A MX 9801171 A MX9801171 A MX 9801171A MX 9801171 A MX9801171 A MX 9801171A
Authority
MX
Mexico
Prior art keywords
hydroxybutylidene
salts
amino
production
acid
Prior art date
Application number
MX9801171A
Other languages
English (en)
Other versions
MXPA98001171A (es
Inventor
Rudolf Kubela
Yog Tao
Original Assignee
Apotex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apotex Inc filed Critical Apotex Inc
Publication of MX9801171A publication Critical patent/MX9801171A/es
Publication of MXPA98001171A publication Critical patent/MXPA98001171A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se proporciona un proceso para la preparacion de ácido 4-amino-1-hidroxibutiliden-1, 1-bisfosfonico o sus sales, el cual comprende: a) hacer reaccionar ácido 4-aminobutírico con ácido de fosforo y tricloruro de fosforo en la presencia de un poli (alquilenglicol); y b) recuperar el ácido 4-amino-1-hidroxibutiliden-1, 1-bisfosfonico o sus sales.
MXPA/A/1998/001171A 1997-02-11 1998-02-11 Proceso para la produccion de acido 4-amino-1-hidroxibutiliden-1,1-bisfosfonico o sales del mismo MXPA98001171A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA2197267 1997-02-11
CA2,197,267 1997-02-11
CA002197267A CA2197267C (en) 1997-02-11 1997-02-11 Process for the production of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof

Publications (2)

Publication Number Publication Date
MX9801171A true MX9801171A (es) 1998-12-31
MXPA98001171A MXPA98001171A (es) 1999-02-01

Family

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Also Published As

Publication number Publication date
US5908959A (en) 1999-06-01
DE69806470T2 (de) 2003-02-20
DK0971938T3 (da) 2002-10-14
BR9807568A (pt) 2000-03-21
WO1998034940A1 (en) 1998-08-13
AU728164B2 (en) 2001-01-04
PL335053A1 (en) 2000-03-27
EP0971938A1 (en) 2000-01-19
ATE220404T1 (de) 2002-07-15
AU5977298A (en) 1998-08-26
EP0971938B1 (en) 2002-07-10
CA2197267C (en) 2000-02-08
ES2180141T3 (es) 2003-02-01
PT971938E (pt) 2002-11-29
DE69806470D1 (de) 2002-08-14
CA2197267A1 (en) 1998-08-11

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees