MX9708753A - Procedimiento de preparacion de formas enantiomeras del acido amino alquilaminofenilo proparanoico. - Google Patents
Procedimiento de preparacion de formas enantiomeras del acido amino alquilaminofenilo proparanoico.Info
- Publication number
- MX9708753A MX9708753A MX9708753A MX9708753A MX9708753A MX 9708753 A MX9708753 A MX 9708753A MX 9708753 A MX9708753 A MX 9708753A MX 9708753 A MX9708753 A MX 9708753A MX 9708753 A MX9708753 A MX 9708753A
- Authority
- MX
- Mexico
- Prior art keywords
- alkylaminophenyl
- amino
- propanoic acid
- phenylalanine
- enantiomeric forms
- Prior art date
Links
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 title abstract 2
- 235000019260 propionic acid Nutrition 0.000 title abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 2
- ASNHGEVAWNWCRQ-UHFFFAOYSA-N 4-(hydroxymethyl)oxolane-2,3,4-triol Chemical compound OCC1(O)COC(O)C1O ASNHGEVAWNWCRQ-UHFFFAOYSA-N 0.000 abstract 1
- GTVVZTAFGPQSPC-UHFFFAOYSA-N 4-nitrophenylalanine Chemical compound OC(=O)C(N)CC1=CC=C([N+]([O-])=O)C=C1 GTVVZTAFGPQSPC-UHFFFAOYSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical compound OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 1
- 150000001412 amines Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- BLNWTAHYTCHDJH-UHFFFAOYSA-O hydroxy(oxo)azanium Chemical compound O[NH+]=O BLNWTAHYTCHDJH-UHFFFAOYSA-O 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedimiento de preparacion de una forma enantiomera del ácido 2-amino 3-(4-alquilamino fenil)propanoico de formula general (Y), en la cual Alk representa un radical alquilo contenido de 1 a 2 átomos de carbono, bajo forma (s) o (r) así como de sus sales, a partir respectivamente de la (L) fenilamina o de la (D) -fenilalanina, por nitracion, luego transformacion de radical nitro de la 4-notro fenilalanina obtenida, de la formula general (II), en la cual R es un átomo de hidrogeno o un radical protector, en un radical alquilamino, después de la proteccion dado el caso de la funcion amino de la fenilalanina.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9506890 | 1995-06-12 | ||
| FR9506890A FR2735126B1 (fr) | 1995-06-12 | 1995-06-12 | Procede de preparation des formes enantiomeres de l'acide amino alkylaminophenylpropanoique |
| PCT/FR1996/000872 WO1996041794A1 (fr) | 1995-06-12 | 1996-06-10 | Procede de preparation des formes enantiomeres de l'acide amino alkylaminophenyl propanoique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9708753A true MX9708753A (es) | 1998-03-31 |
| MXPA97008753A MXPA97008753A (es) | 1998-10-15 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| EP0837843A1 (fr) | 1998-04-29 |
| KR19990022841A (ko) | 1999-03-25 |
| FR2735126A1 (fr) | 1996-12-13 |
| AU6308396A (en) | 1997-01-09 |
| GR3036612T3 (en) | 2001-12-31 |
| DK0837843T3 (da) | 2001-11-19 |
| CZ399497A3 (cs) | 1998-07-15 |
| ATE205471T1 (de) | 2001-09-15 |
| PT837843E (pt) | 2001-12-28 |
| DE69615195T2 (de) | 2002-07-04 |
| WO1996041794A1 (fr) | 1996-12-27 |
| AR002468A1 (es) | 1998-03-25 |
| HUP9900051A2 (hu) | 1999-04-28 |
| BR9608974A (pt) | 1999-02-02 |
| HUP9900051A3 (en) | 2000-07-28 |
| ZA964931B (en) | 1997-01-08 |
| US5969179A (en) | 1999-10-19 |
| IL122531A0 (en) | 1998-06-15 |
| CA2220403A1 (fr) | 1996-12-27 |
| DE69615195D1 (de) | 2001-10-18 |
| JPH11509182A (ja) | 1999-08-17 |
| EP0837843B1 (fr) | 2001-09-12 |
| TW415930B (en) | 2000-12-21 |
| ES2164252T3 (es) | 2002-02-16 |
| NO975150D0 (no) | 1997-11-10 |
| FR2735126B1 (fr) | 1997-07-18 |
| NO975150L (no) | 1997-11-10 |
| SK170197A3 (en) | 1998-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW251274B (es) | ||
| IL113255A0 (en) | New compounds and their compositions having anti-inflammatory analgesic and anti-thrombotic activities | |
| TW200407287A (en) | A sulfonated amine acid derivative and the metalloproteinase inhibitor containing it (I) | |
| EE9700320A (et) | Meetod (S)-3-(aminometüül)-5-metüülheksaanhappe valmistamiseks | |
| PT76450B (de) | Spiro/4.(3+n)-2-aza-3-carbonsaeure-derivate verfahren zu ihrer herstellung diese enthaltende mittel und ihre verwendung | |
| AU5993896A (en) | Semicarbazones having cns activity and pharmaceutical preparations containing same | |
| ATE99698T1 (de) | Peptide. | |
| TW235297B (es) | ||
| HU914092D0 (en) | Process for producing cyclic compounds containing amino or nitro group and acting as enzyme inhibitor | |
| ES8600425A1 (es) | Un procedimiento para preparar semiamidas de acidos alquenilsuccinicos. | |
| ATE108178T1 (de) | Dipeptide, verwendbar als pflanzenwachstumsregulatoren. | |
| TW232009B (es) | ||
| ES8205808A1 (es) | Un procedimiento para la preparacion de nuevos derivados del acido 2-penem-3-carboxilico. | |
| TW355709B (en) | Quinoline carboxylic acid derivative | |
| NO960467L (no) | Bicyklo(2.2.2)oktanderivatcholecystokinin og/eller gastrin-antagonister | |
| MX9708753A (es) | Procedimiento de preparacion de formas enantiomeras del acido amino alquilaminofenilo proparanoico. | |
| ES8406415A1 (es) | Procedimiento analogo para preparar acido (r,s)-5-amino-hepta-5,6-dienoico,acido (s)-4-amino-hepta-5,6-dienoico o sus sales farmaceuticamente aceptables. | |
| MX9605737A (es) | Transfeccion de celulas. | |
| TW333533B (en) | Novel indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase | |
| CA2211681A1 (en) | Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents comprising the same as active ingredient | |
| ES8607332A1 (es) | Procedimiento para preparar sales de derivados de oxazafos- forina | |
| ES2073035T3 (es) | Nuevo procedimiento de preparacion de pro-medicamentos de tipo aza-iperita protegidos. | |
| DK0683785T3 (da) | Anvendelser af aminovinylphosphonsyreestere som lysbeskyttelsesmiddel og stabilisatorer for organisk materiale | |
| EP0220923A3 (en) | Dipeptides and process | |
| NO980994L (no) | Substituerte fosfinsyreforbindelser og deres anvendelse som farmas÷ytika |